Application for Early Career Investigator Mentored Research Award Goal: This program aims to support the development of early career investigators to enter the field of maternal/child HIV research and advance the mission of the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network (http://impaactnetwork.org/aboutus/mission.htm). In coordination with a mentor, early career investigators are invited to propose a project that takes advantage of data and/or samples generated by the IMPAACT network. Eligibility: An early career investigator is someone who is within 10 years of completion of training (from terminal degree or residency training) and is currently an Instructor/Lecturer, Assistant Professor or equivalent at their institution. For this award, IMPAACT aims to fund early career clinician-investigators who engage in participant-oriented research. Funding: There will be a total dollar amount of $100,000 for each award over a 24 month funding period (~$50,000 per year). Funding will cover FTE support for the early career investigator and travel to IMPAACT annual meetings (in Washington, DC area). Funding for equipment will not be allowed. It is expected that the investigator and/or mentor will seek additional funding to cover other research costs, if required. For the funded Early Career Investigator projects, the IMPAACT Statistical and Data Management Center will provide limited data management support and will assign a statistician to provide statistical input and perform data analyses, as needed. This program is not intended for the development of new clinical trials, which should instead occur through standard IMPAACT procedures. Submissions that are aligned with the objectives of the network as outlined by the IMPAACT Scientific Committees at the following web link will be given high priority: http://impaactnetwork.org/research-areas/index.htm. Proposals should include use of existing data and/or stored samples from IMPAACT, PACTG clinical trials or affiliated studies. Use of the IMPAACT web tool for identification of available specimens is encouraged: http://demo.dnsalias.org/ActgImpaactRepositorySite/. Inquiries: Questions may be submitted through the IMPAACT Operations Center at IMPAACT.OperationsCenter@fstrf.org. Key Dates: Proposal Submission Due Date: May 15, 2015 Anticipated Funding Start Date: July 1, 2015 Submission of Proposals: Proposals must be submitted through the IMPAACT Operations Center at IMPAACT.OperationsCenter@fstrf.org by 5:00 PM ET on the due date. IMPAACT Early Career Investigator Program Application Page 1 of 3 16 March 2015 Application Format/Outline A. Early Career Investigator Information Name: Contact information: (Include institution, telephone, e-mail) NIH Biosketch; Include as Appendix 1. B. Research Proposal Summary of Research Plan (400 words) Specific Aims and Objectives (400 words) Research Design and Methods for each Objective (1000 words)* Background and Significance (750 words)* IMPAACT Scientific Committee agenda relatedness (400 words) Expected outcomes for each year of funding (500 words) *Figures used in support of these sections should be included in Appendix 2. References (up to 15) should be included in Appendix 3. C. Mentor Information Name: NIH Biosketch: Include as Appendix 4 Mentorship Plan (1000 words): Specify timelines and measurable outcomes. IMPAACT Early Career Investigator Program Application Page 2 of 3 16 March 2015 D. Budget and Justification For evaluation/illustrative purposes, please provide the budget and justification for the entire 2-year funding period (total costs = $100,000 or ~$50,000 per year), beginning 1 July 2015, as Appendix 5A. For potential award purposes, please provide a prorated budget for the period of July 1, 2015 - November 30, 2015 (5 months) in the amount of $20,834 using the attached budget and justification templates and include as Appendix 5B. The investigator will then be contacted at the time the annual progress report is being prepared (in August 2015) to submit the budget for the following grant year (December 1, 2015 to November 30, 2016) and, in turn in August 2016, for the following funding period, December 1, 2016 through June 30, 2017. Optional: Note outside resources available to the early career investigator that may contribute to the success of his or her program; e.g., institutional support, grant or foundation support (500 words), as Appendix 5C. E. Letters of Support A maximum of four Letters of Support should be included in Appendix 6. IMPAACT Early Career Investigator Program Application Page 3 of 3 16 March 2015
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