The Johns Hopkins ACG® Case-Mix System Version 6.0 Release Notes PC (DOS/WIN/NT) and Unix Version 6.0 – April, 2003 (Revised June 4, 2003) This document was produced by the Health Services Research & Development Center at The Johns Hopkins University Bloomberg School of Public Health © 1991-2003 The Johns Hopkins University. All Rights Reserved Documentation Production Staff Editor in Chief: Jonathan P. Weiner, Dr. P.H. Senior Editors: Chad Abrams, M.A., David Bodycombe, ScD Major contributors: Christopher B. Forrest, MD, PhD, Thomas M. Richards, MS Barbara Starfield, MD,MPH, Hoon Byun, M.A. Editorial Assistance: Klaus Lemke PhD, and Tracy Lieberman. If users have questions regarding the software and its application, they are advised to contact the organization from which they obtained the ACG software. Comments, criticisms, or corrections related to this document should be directed to the Johns Hopkins ACG team (see below). Such communication is encouraged. ACG Project Coordinator 624 N. Broadway - Room 600 Baltimore, MD 21205-1901 USA Telephone (410) 614-3957 Fax: (410) 955-0470 E-mail: askacg@jhsph.edu Website: http://acg.jhsph.edu i Important Warranty Limitation and Copyright Notices Considerable attempts have been made to ensure that the materials included in this document are accurate and appropriate to users’ needs. However, the responsibility for the appropriate application of the Johns Hopkins University ACG Case-Mix System, its supporting software and this documentation rests with the end-user and not the Johns Hopkins University or its agents. No warranty is given or implied that any of the information, methods or approaches discussed in this document are error-free. All terms and conditions associated with the software license, including the Johns Hopkins University and its agents not bearing any liability for actions taken by the user on the basis of software output, are in place and should be understood by the user. THE JOHNS HOPKINS UNIVERSITY HEREBY DISCLAIMS ALL WARRANTIES, INCLUDING THE WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE. Licensed users of the ACG software may copy and distribute this documentation within their organization. To facilitate this process, electronic files (in .PDF format) are available for download at http://acg.jhsph.edu. Individuals not within a licensee organization may download one copy for personal use only, and under no circumstances may they reproduce or distribute this documentation on paper or in any electronic format, beyond this single personal use copy. All copies so downloaded and /or distributed shall contain this notice and the identification of the source of the software shall not be deleted. The terms The Johns Hopkins ACG® Case-Mix System, ACG® System, ACG®, ADG®, Adjusted Clinical Groups®, Ambulatory Care GroupsTM , Ambulatory Diagnostic GroupsTM, Johns Hopkins Expanded Diagnosis ClustersTM , EDCsTM , Dino-ClustersTM , ACG Predictive Model, and acgPM, are trademarks of The Johns Hopkins University. All materials in this document are copyrighted by the Johns Hopkins University. It is an infringement of copyright law to develop any derivative product based on the grouping algorithm or other information presented in this document. Copyright 2003, The Johns Hopkins University. All rights reserved. ii iii Preface Welcome to ACG Version 6.0 We hope that you will share our excitement about this newest release of the Johns Hopkins ACG System. No previous ACG software update has been more significant in terms of additional features over the prior version. No other version has had as many practical benefits for its users. Health care risk adjustment and predictive modeling in general are not simple processes, but the goal of these release notes is to help ease your way into these domains and to get you started as quickly as possible in making full use of the array of features in ACG Release Version 6.0. How to Use This Document This document, the ACG Version 6.0 Release Notes, augments the last comprehensive Johns Hopkins ACG “handbook,” the Release 5.0 Documentation and Application Manual. The chapters provide existing ACG users with all of the information needed to begin to use the new features and capabilities of this latest release. We recommend that first-time users of ACGs also review the Release 5.0 Manual to learn about the core features of the ACG System, including the system’s conceptual basis. Both sets of documents are distributed with the Version 6.0 software, but if you need a copy of the Release 5.0 documentation, it is available on our website at http://www.acg.jhsph.edu. The release notes are organized into six sections as follows: 1. An overview of new features in ACG Release 6.0. This will quickly introduce you to both the new areas of functionality and the modifications and updates of previous features. 2. A comprehensive description of the new state-of-the-art predictive model, the acgPM, which includes performance data and application suggestions. 3. Details of the additions to and refinements of the expanded diagnosis cluster (EDC) disease-marker methodology, including several new reports that combine EDCs and ACGs. 4. Introduction of the new “internal” relative value weights for ACGs that are now included in the software. 1 5. Suggested guidelines on how to make the best use of the tools and methodologies now found in the ACG System. This section will help you quickly get to the bottom line, and thus supports mission-critical clinical and financial management decisions. 6. A detailed technical software installation guide that describes all updates and includes operating instructions like those found in the previous ACG version. You will need only this section (and no previous documentation) to run the software. We hope and expect that you will find the latest ACG software and this accompanying documentation of value to you and your organization. As always, the Johns Hopkins ACG development team welcomes your feedback. Please forward comments, questions, or suggestions for improvement about this release document or our software to askacg@jhsph.edu. 2 Section 1 Overview of New Features in ACG Version 6.0 The Johns Hopkins University ACG development team is very pleased to distribute version 6.0 of our ACG risk-adjustment/case-mix software. This software includes several enhancements that significantly expand both the breadth and depth of the Johns Hopkins ACG suite of diagnosis-based health care measurement tools. This version reflects our ongoing commitment to continued improvement and refinement of the ACG System. Now more than ever, the ACG toolkit can serve as the measurement engine for a full array of health care applications, including clinical care management, resource management, health services finance and payment, and applied evaluation and scientific research. Some of the new features in version 6.0 will advance and expand the clinical grouper and measurement tools available to the experienced user. Other improvements will make the ACG System easier to use for those just starting out. Many changes and enhancements will be of value to both groups. As noted in the Preface, the key enhancements included in Version 6.0 include: • predictive modeling (including new reports), • additions and refinements to the expanded diagnosis cluster (EDC) methodology (including new reports), • updating ICD-9 codes, • relative risk factors based on nationally representative data, and • an updated installation guide. a. AcgPM: Predictive Modeling for High-risk Case Identification and Future Costs The ACG Predictive Model (acgPM) permits the rapid identification of high-risk patients who may benefit from care management services. The acgPM is the focal point of several notable innovations: • focus on individualized care management, • incorporation of a new hospitalization propensity index, • ability to employ pharmacy use data where available, • integration of elements of our EDC technology, and • incorporation of a unique regression modeling strategy. 3 The acgPM remains grounded in the disease burden perspective unique to the ACG System, one that focuses on commonly occurring patterns of morbidity and assessment of all types of medical need. The model also shares the modest data requirements of the ACG System. This state-of-the-art predictive modeling risk identification module builds on the many facets of the ACG system and several years of intensive research and development at Johns Hopkins. According to all empirical assessments to date, the accuracy of the risk prediction measures calculated by the acgPM equals or surpasses other available methods. One of the outputs of the acgPM model is based on a sophisticated logistic regression equation that maximizes the tool’s ability to identify your members who will be among the very highest cost users in the next year (or some other future period). With the same data that you use to assign standard ACGs, the acgPM module assigns each individual within your organization a risk Probability Score that can be employed to array the members of your population from the lowest to the highest risk. As described in the following section, evaluations of the acgPM Probability Score indicate that it is more accurate than case identification derived from prior use/prior (cost) experience. Unlike other case identification methodologies based on extended hospital stays or repeat specialist visits, the acgPM method helps to identify many persons before they actually become expensive. Another set of outputs is based on linear OLS (ordinary least squares) regression and can be used to provide an estimate of cost for each individual in the subsequent time period. Termed the Predicted Resource Index (PRI), this index can be used to assist clinical administrators, actuaries, and others interested in valuing future expectations of resource use. This index can be used for a wide range of actuarial/financial applications such as setting risk-adjusted capitation payments or setting premiums. In addition to offering measures of risk related to overall service use, the acgPM includes a special component for predicting an individual’s risk of using pharmaceuticals. Moreover, the acgPM can incorporate prior pharmacy use data, when obtainable, to improve the accuracy of its predictions. If prior pharmacy use data are available within an organization, this combination of pharmacy and the typical ACG risk factor information derived from ICD diagnosis information is a powerful means for identifying individuals at risk of high future resource use. 4 As discussed in more detail in the main body of this document, automatically generated acgPM reports combine the Probability Score and the PRI. This enables users to focus attention quickly on those individuals with case-manageable conditions at greatest risk for future high expenditures and to provide estimates of what these individuals might cost if no intervention is taken. b. Additions and Refinements to the Johns Hopkins Expanded Diagnosis Clusters The expanded diagnosis cluster (EDC) “disease marker” system originally emphasized commonly occurring conditions treated primarily in ambulatory settings. For this version, the EDC mapping underwent considerable refinement. To provide a more comprehensive categorization approach for profiling morbidity, EDCs now include less commonly occurring conditions, many of which may require hospitalization. All in all, 40 new EDC categories have been added and affect 16 of the 27 major EDCs (MEDCs), and several existing EDCs have been subdivided to provide additional clinical specificity. To facilitate quick implementation of the EDC typology, the software print file now incorporates a series of EDC-based “standardized morbidity ratios” (prevalence of EDCs within your population, after controlling for age and sex) as well as a series of combined ACG/EDC tables to help support case-management and disease-management programs. c. Updating ICD-9 Codes The ICD-9 mapping tables for both the EDC and ACG/ADG groupers have been updated to include all new codes introduced in the Center for Medicare and Medicaid Services official ICD-9-CM (Version 20). As in years past, old or retired ICD-9 codes have been retained as part of our algorithm because they were once valid and/or their interpretation is reasonably clear. d. Available Relative Value Weights for ACGs and RUBs A key strength of the ACG suite of case-mix/risk adjustment measures is that the grouping algorithms and analytic approaches in the software are very accessible to most organizations. The straightforward ACG actuarial cell approach readily allows for the application 5 of an organization’s own information to calibrate “weights” (or coefficients) to fine-tune the analysis to best match the local situation and context. While many users of ACGs have applied actuarial cell-based models, there is a growing body of users who wish to implement risk adjustment and for whom no local cost data are available To facilitate quick implementation of ACG technologies, Version 6.0 for the first time incorporates concurrent (i.e., same-year resource use) ACG weights based on a large research database (more than 2 million persons) younger than 65 years of age who were enrolled in several U.S. commercial health insurance plans. Version6.0 also makes available individual assignment to one of six ACG categories (from low to high) termed ACG Resource Utilization Bands, or RUBs. Relative value weights for each RUB category can be calculated by using local cost data or by using the concurrent ACG weights built into the software. The supplied RUB categories cover six morbidity levels: non-users, healthy users, low morbidity, moderate morbidity, high morbidity, and very high morbidity. Figure 1 illustrates the percentage of the population and percentage of total dollars associated with each RUB (based on a large research population); the bottom 40% of the population consume less than 3% of all health care dollars while the top 0.7% in the highest RUB category consume over 15%. RUBs can be used in the same fashion as ACG assignments. For many applications, they dramatically simplify risk adjustment computational tasks while retaining considerable ability to explain variations in resource use that are attributable to casemix. 6 Figure 1: Distribution by ACG Comorbidity RUB Distribution of ACG Comorbidity RUB % of P opulation % of Dollars 50.0% 45.1% 40.0% 30.0% 28.3% 25.8% 27.6% 24.4% 20.0% 13.9% 15.2% 12.5% 10.0% 0.4% 3.7% 2.4% 0.7% 0.0% Nonusers Healthy Users Low M oderate High Very High ACG Comorbidity RUB Level The relative values and RUB assignments available within the current version of our software are also used to generate tables that combine ACG and EDC information to develop a series of summary reports. These reports are discussed in Section 5 of the Release Notes, Selecting the Right Tool from the Expanding ACG “Tool Box”. The software-provided weights may be considered viable “external” or “reference” weights for concurrent ACG or RUB analyses. These weights can be used as substitutes for locally calibrated weights by those organizations with no available resource-use measures, or whenever the population may be too small to produce reliable local weights. (In addition to the section on this topic in the Version 6.0 Release Notes, please see Chapters 6, 8, and 11 of the Version 5.0 Documentation and Application Manual for further discussion of the advantages and disadvantages of local versus “software-provided” reference weights). e. Technical Notes Although the functionality of Version 6.0 is greater, there are only modest changes from Version 5.0 in terms of how to load and execute the software. Those familiar with the operation of ACG Version 5.0 will find it easy to implement 6.0. All new features follow from the 7 incorporation of a few new “reserved words” in the ACG control card file (used to pass data to the software and to control what fields are written to the software’s output file). Readers should review the Installation and Usage section to familiarize themselves with the technical details and new specification requirements for 6.0. The guide included in this document can stand alone, and there should be no need for programmers or analysts running the software to refer to the previous Version 5.0 Manual. 8 Section 2 The ACG Predictive Model: Helping to Manage Care for Persons at Risk for High Future Cost This section introduces the ACG Predictive Model (acgPM), an advanced tool for projecting future resource use based upon concurrent data captured largely from standard claims files. In addition to background on predictive modeling and on the construction of the acgPM, the text also provides model performance specifications, and concludes with a discussion of output reports and how they may be used to support case and disease management. a. Introduction This chapter describes the newest addition to the ACG System’s toolkit, the ACG Predictive Model (acgPM). The acgPM uses sophisticated statistical techniques to project the impact of co-morbidity and other factors on an individual’s use of health care resources in a subsequent time period. The acgPM is designed for prospective high-risk case identification and will be of real value for assessing both the quality and appropriateness of patient care. We begin with an overview of the acgPM and then launch into a discussion of our acgPM development effort, the elements of the new models, and model performance assessment. We conclude the chapter by addressing application issues. i. Model Offers Fast Identification of High-risk Patients The acgPM permits the rapid identification of high-risk patients who may benefit from care management services. The acgPM remains grounded in the disease burden perspective unique to the ACG System, which focuses on commonly occurring patterns of morbidity and assessment of all types of medical need. This holistic method has repeatedly proved to have many advantages over comparable case-mix adjustment approaches that include only a limited set of disease or episode categories. Also, our predictive model’s straightforward approach to integrating clinically relevant risk factors offers advantages over “black box” strategies based on complex clinical algorithms for data-mining or on artificial intelligence. The Venn diagram provided in Figure 1 graphically depicts the predictive modeling challenge. Traditionally plans have made use of data on prior experiences (the Actual High-risk 9 Year 1 ellipse) to project individuals likely to remain costly in the following year. This projection represents an amalgam of patients that includes those who have continuing chronic conditions and also those who go through acute events or injuries that do not recur. The acgPM identifies another group of individuals (the Predicted High Risk ellipse) that overlaps the priorcost ellipse but also identifies individuals who were NOT high cost in Year 1 (the shaded area). Thus an important attribute of predictive model performance is the size of the shaded area. Figure 1. Identifying High-cost Persons Who Were Not Previously High Cost ii. Model Outputs Serve Dual Purposes The acgPM software produces two types of predictive risk indicators: (1) a probability score representing the likelihood that a member will be among those persons using extraordinary health care resources in the coming year and (2) a predicted resource index that expresses anticipated resource use as a relative value. Probability scores are used because the clinical decision-making process is often couched in terms of likelihood or odds. When employing the probability score, users can set their own definition of high resource use by setting some minimum threshold. Thus, for the purposes of case management, a health plan might choose to consider only those individuals with a probability of .6 or more of falling within the “high-risk” group during the following year. Our experience suggests this cut-off would identify about one half of 1% of the plan’s members. There are performance tradeoffs to be made (e.g., increased positive predicted values with lower sensitivities) when setting minimum thresholds. Setting higher probability thresholds permits 10 prediction with greater accuracy but with a greater chance of missing potentially high-risk cases. These tradeoffs are discussed later in this chapter. The acgPM probability score has been tailored to case identification and thus will be especially useful to case managers in targeting patients for intervention. The second acgPM output, the predicted resource index, can be applied to calculate expected resource dollars. Case managers will be able to calculate expected differences between current and projected future costs to prioritize interventions that could have the highest impact. Health plans and others will also find this model output to be a useful tool for rate setting and financially related decisions. iii. Models Forecast Overall and Pharmacy-specific Expenses The acgPM output provides two separate sets of probability scores and predictive resource indexes: the first for total cost, and the second for pharmacy-specific cost. The total cost output represents an overall measure of inpatient and outpatient resource use that is the main focus of the prediction model. The model also provides pharmacy resource predictors because pharmacy-specific cost has become a major component of overall expenditures and is currently the focus of many payment and delivery organizations. Although there is a correlation between medical care service use and pharmacy use, the relationship is not one-to-one. Disease management evaluations are showing that total cost savings can be achieved, primarily because of reduced inpatient care, while pharmaceutical use increases. iv. Identification by Prior Costs Alone Omits Many Cases Prior cost and other utilization experience (e.g., extended hospitalization) are often used as the basis for identifying individuals for inclusion in intensive case management. Chronically ill individuals who have had significant health care use in the past often do continue these patterns of high care use into the future. Prior use measures also identify patients with a highcost acute event, which may have no bearing on healthcare use in the future. Still others who had previously been less intensive users of health care resources may enter a high-use phase. For especially high-risk cases, reliance on prior use alone will yield a very incomplete picture. In 11 Figure 2 we have pooled together those persons within a large health plan data set whom were successfully predicted to be high use (cost) by either the acgPM or by prior cost experience.1 Figure 2. Percentage of Cases Correctly Predicted to Be at High-risk for Using Extraordinary Health Care Resources, by Prediction Strategy acgPM 46% Prior Cost 27% acgPM Both 27% Prior Cost Both Overall, the acgPM identified 73% of the high-risk cases that were successfully captured by either approach. The acgPM uniquely accounted for nearly half of the successfully identified high-risk patients. These cases were not previously high resource users and would be missed if prior cost alone were used in case identification. v. The acgPM Adds Another Tool to the ACG System Without Increased Data Collection The acgPM substantially improves high-use case identification and does so without increasing the minimal data collection effort currently required for the ACG software. The acgPM constructs its risk factor information from claims data streams containing only age, sex, and diagnostic information. If a plan has historical pharmacy-cost information for each person (the full drug claims history is not needed), this summary measure of pharmacy use can optionally be added to the input data stream for enhanced model performance. Moreover, the 1 The high risk group in this comparison included those with an acgPM probability score of 0.6 or more of being among those persons with the top 5% of total costs next year. An equivalent number of the highest prior cost cases in year –1 were then identified for comparison. These two groups each account for about ½ of 1% of the test population. 12 acgPM is bundled within the current ACG System, and thus the full capabilities of ACGs, including provider profiling and risk-adjusted capitation determination, are available as part of the standard software package. b. Developing the acgPM i. What is a Predictive Model? Predictive modeling in the health care management context is generally defined as a process that applies existing patient data to identify prospectively persons with high medical need who are “at risk” for above-average future medical service utilization. Such future resource use is often, although not always, linked to negative health outcomes. A predictive model can incorporate information from a wide array of sources and can rely on many statistical approaches—from the very simple to the very complex. As noted, one simple approach is to use contemporary cost data as a predictor of future high cost. For example, a plan could assume that if a person is very high cost this year, he or she is likely also to have a high care-utilization experience in the future. Other models use multivariable statistical analysis and data available from a range of sources for their predictions. The basis for many of these efforts is ordinary least squares regression. Some predictive models are based upon neural networks. These are sometimes termed “artificial intelligence” approaches, given that neural networks represent collections of mathematical models that emulate the processes observed in biological nervous systems, including the capability to “adapt and learn.” From the perspective of either empirical accuracy or performance, no modeling method has yet to demonstrate clear superiority. One of the main challenges facing any modeling strategy is the limited risk factor data on which the models can be based. Currently, the commercially available prediction tools depend largely on standard medical care claims (age, sex, diagnoses, procedures, prescriptions, service dates, and cost). Model coefficients are developed using one year’s data to “predict” a second year. With the limited source of risk factor data, model predictive capabilities are limited as well. All predictive models are tools that must be used with good clinical and managerial judgment and other sources of information in making decisions. 13 ii. Historical Use of ACG for PM Although a separate predictive model is new to the ACG System as of version 6.0, for years elements of the ACG case-mix grouping algorithms have been successfully adapted by users to apply their own customized predictive models. ACGs work very well for this purpose because, at their core, they focus on the dimensions that help predict high risk, such as: • • • • • persistence of the conditions, seriousness/severity of the conditions, the co-morbid nature of disease, the likelihood of a negative outcome, and the need for high levels of medical services. Prior work by Starfield et al. (Primary Care, Co-morbidity, and Case Management, presented at the Conference on Health Care Risk Adjustment, Minneapolis, MN, May 2, 2001 and available in the virtual ACG library at: http://acg.jhsph.edu) suggests that the components of the ACG System have inherent utility as predictors of high future costs. As is shown in Table 1, the co-occurrence of ADGs and the presence of selected ACGs are superior to prior hospitalizations in predicting high costs in subsequent years. Table 1. Potential Influence of Prior Co-Morbidity and Hospitalization on Future Cost. Measure 2+ Hospitalizations 12+ ADGs 4+ Major ADGs Selected ACGs Total Percentage of Members 0.7% 0.9% 0.4% 1.7% <3.7% Percentage High Cost in Year 2 53.3% 65.6% 72.4% 60.0% Percentage High Cost in Year 3 51.5% 66.1% 70.1% 52.0% For other successful applications of the ACG System components to predict high-risk cases, see the proceedings of the 2002 International Johns Hopkins ACG Risk Adjustment Conference, Baltimore, MD, April 28, 2002 (available in the virtual ACG library at: http://acg.jhsph.edu). 14 c. The “Nuts & Bolts” of the acgPM Model i. Specifying the Predictor Variables The acgPM modeling strategy makes use of the comprehensive array of morbidity metrics that are available within ACGs. The model incorporates the morbidity-based ACGs, selected disease-specific EDCs, and a newly developed diagnostic indicator of the likelihood that someone will be hospitalized in an ensuing year. We have also added an indicator of the level of prior pharmacy use. First, a brief word on the issue of prior-use measures. Prior use is a fallible indicator of future use because it includes many acute conditions that get resolved. The acgPM focuses on individuals with a high morbidity burden and with high-impact chronic conditions that are likely to continue to require significant health care resources. Prior-use measures are also not appropriate as “risk factors” for “risk-adjusted” rate setting or profiling as they potentially could provide incentives to overuse resources. That is, providers can readily increase the risk rating of their patient (and potentially reimbursement) simply by ordering more services. Including prior use is appropriate for high-risk case identification since the goal is to identify and potentially intervene among high-cost users. Several alternative prior-use measures were assessed for inclusion in the acgPM model, but levels of previous pharmacy expense proved to be the most powerful resource predictor with the clearest clinical implications and with a minimal addition to the burden of data collection. The acgPM “risk factor” variables used in the model are as follows: • • • • • • • age (seven age groups from infants to 64 years of age), sex, ACGs (three broad morbidity groupings from low to high in addition to selected individual ACGs), a “hospital dominant” marker (reflecting diagnoses where hospital care was “dominant,” though care could be provided in a variety of settings), identification of pregnancy, where no delivery has yet occurred, pharmacy expense levels, and EDCs (a limited set that represent high impact and chronic conditions). Specific EDC disease markers were incorporated into the model if they represented • • common high-cost chronic conditions that were frequent targets for disease management programs, uncommon, but high impact on both cost and health, conditions, 15 • • • conditions for which the evidence linking health care to outcomes is strong, complications that potentially signify instability in a chronic illness. (e.g., retinopathy), or conditions that are a major biologic influence on health status (e.g., transplant status, malignancy). The focus of the current acgPM software release is on the non-elderly (i.e., under 65 years of age) population. The specific ACGs and EDCs that were used in building acgPM are documented in Appendix 1. ii. Defining the Model Outputs As noted earlier, the acgPM model offers two types of outputs: a probability score of being a member of the high-risk1 group next year and a predicted resource index reflecting expected cumulative resource use. The two indicators are intended for different purposes (case selection for the former and cost estimation for the latter) and benefit from somewhat different statistical methodologies. Probability scores range between zero and one. For example, conceptually, an individual with a probability score of .4 has a 40 in 100 chance of being in the high-risk cohort next year. The predicted resource index ranges from zero to roughly 40 with a population mean of 1.0. The index can be readily converted to a predicted dollar amount. These two outputs are repeated for both total costs and for pharmacy costs only. The Johns Hopkins ACG development team chose to use logistic regression (logit) to develop the probability score for a patient becoming a member of the high-risk group next year. This is an important departure from the prevailing strategies for high-risk case identification that usually employ ordinary least squares (OLS) regression based on linear modeling strategies. Logit models are best for predicting events (yes/no occurrences)—in this case, being a high user of resources In terms of estimating resource use using multivariate methods, regression is the most effective strategy for estimating dollars. Therefore we used an OLS model for the resource-use prediction component of our model. The acgPM’s predicted resource index is presented as a 2 Based upon repeated testing of alternative thresholds, for model development we have defined “high risk” to represent individuals whose predicted costs for the following year are expected to fall within the top 5% of a plan’s members. This choice of high risk definition does not preclude users from adopting other definitions, e.g., the top 1%, ½ or 1% or even top 10% of plan members. 16 relative value that can be adjusted to reflect local mean costs. This adjusted scale can be readily converted into dollar amounts comparable to future cost estimates by a simple algebraic process. The process for deriving dollar values is discussed later in this chapter. d. A Framework for Discussing the Performance of Predictive Models There are many different ways to apply the acgPM model, and each organization will have unique data and contextual issues. Furthermore, there are few standard approaches in the literature for evaluating the “accuracy” of any predictive model for resource use. Thus assessing and reporting the performance of predictive models is not straightforward. We are providing users with several alternative ways to assess performance because ACG users tend to be discerning with regard to appropriate methods and statistical techniques. What follows is a summary of an evaluation that assessed the performance of our models in helping to identify persons who are members of high-risk/high-cost cohorts in the subsequent year. We tested the models using actual data from a very large data set, consisting of over two million lives enrolled in several health plans. We adopted a split half approach, using a random selection of half the observations to build the models and the other half of the observations to validate the model. The performance figures reported in the following section are based on the validation half of the data. Unless otherwise specified, we apply the version of our model that includes pharmacy cost as one of the risk factor inputs. One way to assess predictive models is to ascertain how well they classify cases as actually being a member of a high-risk group in a future period. This yes/no accuracy assessment is similar in many ways to the statistical/epidemiologic approaches that are used to assess the accuracy of diagnostic screening tests or exams. However, this quantitative approach does not tell the full story regarding model performance. Other important questions are, What are the prediction characteristics of the model? and Can it aid in the identification of cases where intervention is possible and where care can be improved? There is no explicit “test” to determine this result, but our performance assessment attempts to consider this capability as well. Epidemiologists often use sensitivity and specificity to assess the validity of screening tests. These performance indicators are defined as follows: • Sensitivity is the percentage of true high-risk cases that are successfully identified: 17 Sensitivity = true positives/(true positives + false negatives). • Specificity is the percentage of true low-risk cases that are successfully identified: Specificity = true negatives/(true negatives + false positives). Specificity is not especially useful in assessing this or any other predictive model since the focus is on only a very small subset of high-risk persons and a large number of true negatives. Positive predictive value (PPV) represents a potentially more useful alternative to sensitivity. • PPV is defined as the probability that someone predicted by the model to have high expected Year 2 resource use does, in fact, have high Year 2 resource use. Mathematically, this is expressed as: PPV = true positives/(true positives + false positives). A PPV score gives information about the likelihood that a person who tests “positive” (in this case is predicted to be high-risk) actually will be a high-resource user in Year 2. Finally, another widely used measure of the ability of such models to correctly classify patients is the c-statistic. The c-statistic provides an overall measure of model performance and represents the probability that an observation is correctly classified as a true positive or true negative along a continuum of “test thresholds” (in this case probability score thresholds). The closer the c-statistic is to 1.0, the better the model. For a summary of these and other performance indicators that are often applied to diagnostic tests and predictive models, see Appendix 2. e. Performance of the acgPM Model We sought to assess our model’s performance by asking several key questions: • • • • How well does acgPM improve upon prior cost alone in identifying high-risk cases? Do the cases identified by the model represent a group meriting intervention? How well does acgPM do in estimating future costs of care? What added predictive value is gained by including the optional pharmacy cost predictor? 18 i. How Well Does the acgPM Improve on Prior Cost Alone in Identifying High-risk Cases? The statistical properties of the acgPM total cost model are compared to prior cost only predictions in Table 2. The performance of the acgPM is shown with respect to a series of probability “thresholds” based on the prediction scores output by the model for all members of a large health plan “test” population. Table 2 shows the acgPM’s accuracy at six different probability score cut-offs within the large health plan test population of about 410,000 persons (under the age of 65 years). By setting the risk threshold low, e.g., .4 or higher, a higher percentage of cases is included (in the example, about 1.33% of the population). Set the risk threshold higher and select a lower percentage of cases (only 0.10% at a minimum threshold of .9 or higher). Thus certainty, expressed as the PPV, comes at a price. By setting a high threshold, you come close to certainty that every case you select will become high cost in Year 2. Set a lower threshold and there is less certainty but a higher likelihood that you’re picking up all the potentially high-cost cases. Even with probability floors as low as .4, the likelihood is still better than chance (via PPV) that an acgPM-predicted high-risk patient will actually turn out to be a high consumer of resources. For comparison purposes, in Table 2 we also show performance statistics associated with using prior cost as the only predictor in an identically sized group. That is, we identified the highest cost individuals from Year 1 on the basis of actual experience. This “prior cost” cohort was selected to be exactly the same size as the number of individuals identified using the various acgPM probability thresholds (see the proportion of population in column 2 of Table 2. Table 2 indicates that the acgPM consistently outperforms prior cost in predicting actual Year 2 cost. Sensitivity for both the acgPM and the prior cost groups is low given that these represent very small highly targeted groups and thus do not capture many cases. However, as the PPVs suggest, most of the identified cases turn out to be truly high cost in the following year. 19 Table 2. Model Performance (Total Cost) at Different acgPM Probability Scores vs. Samesized Prior Cost Cohort Prior Cost* acgPM Probability Score Threshold .4 .5 .6 .7 .8 .9 Percentage of Population 1.33% 0.89% 0.63% 0.42% 0.25% 0.10% Sensitivity PPV Sensitivity PPV 0.16 0.12 0.09 0.06 0.04 0.02 0.59 0.66 0.72 0.76 0.80 0.84 0.12 0.09 0.07 0.05 0.03 0.01 0.46 0.50 0.54 0.57 0.62 0.69 Based on a validation sample of approximately 410,000 covered lives. Prior cost cohorts were chosen to the same size as acgPM high-cost cohorts, i.e., if selecting cases with an acgPM probability score of .7 or higher yielded 100 predicted high-risk patients, the prior cost comparison would be the 100 cases at the highest Year 1 cost. * ii. Do the Cases Identified by the Model Represent a Group Meriting Intervention? There is a clear distinction in terms of mean cost between cases identified by the acgPM as potentially high-risk and those not so identified. As shown in Figure 3, predicted high-risk cases proved to be nearly 13 times as expensive in actual Year 2 dollars as those not so identified. Individuals identified as being high-risk for pharmacy service use were almost 14 times as expensive as those not so identified. The model, thus, is identifying cases that are quite distinct in terms of very high resource use. 20 Figure 3. Mean Costs of High-risk Versus All Other Cases by Cost Category Dollars $15,000 $13,787 Top 5% All Other $10,000 $5,000 $2,532 $1,072 $189 $0 Total Pharmacy Type of Cost *With an acgPM probability score of 0.4 or higher. The model also preferentially captures cases with chronic conditions for which case management services are often available. As shown in Table 3, the acgPM-identified “at-risk” group includes a higher percentage of these potentially case manageable chronic conditions than does prior cost. Table 3. Percentage of Selected Chronic Conditions in “High-risk” Cohorts Identified by acgPM and Prior Cost Approaches. Condition Hypertension Low Back Pain Diabetes Ischemic Heart Disease Arthritis Lipoid Metabolism Congestive Heart Failure Asthma COPD Depression Chronic Renal Failure Percentage of High-risk Cohort acgPM Prior Cost 37.91 26.96 27.42 17.19 24.00 13.39 17.83 22.72 17.26 13.33 21.49 13.30 8.45 7.42 14.03 6.87 10.01 7.05 11.00 4.85 5.66 5.40 21 iii. How Well Does acgPM Do in Estimating Future Costs of Care? The acgPM offers a predictive resource index that is a relative value for resource use related to both total and pharmacy costs in Year 2. This relative value can be used for many applications including the estimation of future expenditures for specific subgroups of patients who are targeted for case management. The probability model results and the linear modeling results can work in tandem. The acgPM’s probability score output is recommended for selecting patients, while the predictive resource index is recommended for calculating expected costs (or potential cost savings) for population subgroups. The R-squared statistic is commonly used to assess the performance of OLS-based linear models. The R-squared expresses the percentage of variation in the outcome variable that is explained by the model. We believe this is an appropriate evaluative benchmark for cost predictors calculated on a linear basis (in our case the relative weight for resource use) but not for yes/no logistic predictions (such as our risk probability score). When assessing our predicted resource index model, the performance characteristics of the acgPM are comparable to prior cost: the acgPM explains 14% of the variation in total charges compared to 12% for prior cost. iv. What Is the Performance “Bonus” if Pharmacy Cost Data Are Available as a Risk Factor? When they are available, we encourage the use of pharmacy cost data as a source of riskfactor information2. The acgPM performance statistics presented in the preceding text are based on models that include pharmacy cost as an input variable. We compare the performance of the acgPM probability score based on models with and without pharmacy cost data in Table 4. While there is added information if pharmacy costs are available, if they are not available, the performance penalty is not high, especially in predicting total costs. 3 The acgPM model includes a simple five category variable based on previous pharmacy cost history. Each person is placed into one of five groupings, from very low to very high. 22 Table 4. Performance Characteristics of acgPM with and without Inclusion of Prior Pharmacy Cost as a Risk Factor Model Sensitivity PPV C-Statistic 3 9 6 32 66 72 60 71 0.79 0.81 0.87 0.93 acgPM Total Cost acgPM Total Cost with Pharmacy acgPM Pharmacy Cost acgPM Pharmacy Cost with Pharmacy Model performance data are based on an acgPM probability score threshold of 0.6, representing approximately half of 1% of the population for total cost and the top 2% of the population for pharmacy costs. The inclusion of prior pharmacy costs as a predictor variable for the predicted resource index has little impact on the model’s R-squared associated with total cost (.14 up from .11). However, the addition of the pharmacy categorical cost information does have a significant impact on the R-squared associated with prediction of next year’s pharmacy use (.34 up from .17). Understandably, it does appear that prior pharmacy cost is an important factor in predicting future pharmacy costs. Users who wish to focus on pharmacy cost would be advised to incorporate prior cost data if they are available. f. Reports The software currently puts two reports into the ACG output stream: and (1) High Risk Individuals and Expected Resource Use by Disease Category and (2) Frequency and Percent Distribution of Probability Scores. Each report is discussed below. i. High Risk Individuals and Expected Resource Use by Disease Category This report (see Figure 4) shows how your population is distributed by EDC category and how they are predicted to consume resources among some of the “riskier” probability levels. The columns represent a range of probability scores from a minimum value to the highest reported value. The 11 EDCs represent chronic conditions that are often the subject of case and disease management initiatives. For an example of how to use this report see the following section (Application Issues). 23 Figure 4. acgPM Report One. ii. Frequency and Percent Distribution of Probability Scores This report (see Figure 5) is intended to provide you with a sense of how your population is distributed according to probability score. The information is intended to help you establish the size of potential cohorts for case/disease management. This distribution will, of course, change within specific EDCs. Figure 5. acgPM Report Two. g. Application Issues i. Using the acgPM Case Management Report As described in the section on model performance, the acgPM identifies a group of patients distinct from those who would have been selected by prior cost alone. Further, this group of patients appears to have a higher percentage of those who are typically case managed. To illustrate how the model might be used to better target individualized case management 24 interventions, we provide a sample output report (Table 5) as produced by the acgPM software (if users request this with a control card). For a series of probability thresholds, the table shows how individuals in a large health plan are distributed within selected chronic disease groups and how their acgPM predicted resource use varies for each risk-level cohort. The diseases represent a sampling of some of the conditions for which “disease management” or “case management” services are often available within an integrated delivery organization. These chronically ill patients are all projected to use resources well above the plan’s average (of 1.00). In a comparison of the three potential “case management” cohorts defined on the basis of the three alternative acgPM probability score thresholds (i.e., .4 or higher, .6 or higher, .8 or higher), the projected intensity of resource use generally doubles from the lowest to highest risk group within each disease. Moreover, when resource use in the top acgPM risk category (with a score of .8 or higher) is compared with the cohort of persons with the disease, but who were not identified as being in one of the top tier risk groups (i.e., those with probability score of less than .4), the predicted expenditure variation is dramatic—at times almost ten-fold. Persons with chronic renal failure experience very high predicted resource use within all of the probability score cohorts. To a lesser degree, the same is true for congestive heart failure. For conditions such as these, projected resource use appears to be high regardless of the probability level. Aside from employing individualized case management, it may be especially appropriate to employ disease management programs that address the cohort of patients with these diseases. It is evident that persons within each disease group will require a different approach to care management, but the various predictive measures produced by the acgPM system will provide valuable additional information to allow clinical professionals to better design and implement these interventions. All of the remaining diseases that are depicted in Table 5 appear to be appropriate candidates for case management. To have the greatest impact, it would be useful to focus on those individuals at higher predictive risk levels who are currently experiencing relatively low resource use. Our experience suggests that at least 10% of patients will fall into this group. Finally, it is important to consider the comorbidity profiles of these high-risk groups. It is likely that high risk cases are affected by multiple diseases and that the condition reported in 25 Table 5 may not be the primary cost driver. Thus patterns of comorbidities should also be assessed in the course of planning case management initiatives. Table 5. The Number of Cases and Associated Predicted acgPM Relative Resource Use by Alternative acgPM Risk Probability Thresholds for Selected Chronic Conditions Number of Cases Probability Score Category Disease Category Arthritis Asthma Diabetes Hypertension Ischemic Heart Disease Congestive Heart Failure Hyperlipidemia Low Back Pain Depression Chronic Renal Failure COPD Total 17,679 27,863 16,991 50,122 9,330 1,634 31,240 61,980 10,190 742 6,204 ≥0.4 ≥0.6 940 463 764 386 1,307 716 2,064 1,011 971 514 460 292 1,170 529 1,493 723 599 298 308 253 545 301 ≥0.8 Mean Predicted Relative Resource Use Probability Score Category <0.4 ≥0.4 ≥0.6 ≥0.8 172 2.18 9.22 136 1.43 9.02 345 2.67 11.03 457 2.06 10.34 242 3.27 10.70 184 5.17 13.94 186 1.97 9.15 279 1.76 8.64 113 2.09 8.82 183 13.11 22.33 147 2.58 10.84 11.69 11.25 13.87 13.57 13.64 16.90 11.59 10.89 11.03 23.60 13.38 15.71 14.85 17.36 17.57 17.33 19.61 15.46 14.27 14.30 25.21 16.68 There are trade-offs involved in setting probability threshold levels for case identification. The higher the minimum probability, the greater the projected resource use, but also the smaller the target group. As noted earlier, higher probabilities also improve the likelihood that cases identified do indeed turn out to be high resource users. The performance implications at a range of thresholds based on the acgPM probability score among a large test population are depicted graphically in Figure 6. 26 Performance Scale Figure 6. Trends in Model Performance, by Probability Threshold 0.9 0.8 0.7 0.6 0.5 0.4 0.3 0.2 0.1 0 Sensitivity Positive Predictive Value 0.1 0.2 0.4 0.5 0.6 0.7 0.8 0.9 Probability Threshold The user’s choice of a case identification probability threshold relates to the desired application, availability of resources for case management, and prevailing local practices. Depending on the intervention an organization might prefer to maximize sensitivity, while at other times, maximization of predictive value might be the goal. For example, when implementing a customized web-based informational campaign within a health plan, the goal may be to contact the highest 5% or 10% of the persons “at-risk.” This goal could represent all those persons with a probability score of .1 or higher. Based on the sensitivity of the model at these probability levels, it may be possible to capture over 50% of those persons who will be members of the highest resource use cohort next year. However, the PPVs for this group will be in the .25 range, and thus most of these individuals will not actually be members of the highest resource use group next year. But given the non-intensive nature of the intervention, that is of small concern. Moreover, even the individuals targeted for this program who do not end up in the highest resource group in the subsequent period (the false positives) will still have risk and associated resource use that is far higher than the underlying population. Many types of individualized case management can be quite resource-intensive in their own right, and so there should be a high likelihood that persons targeted for case management are, in fact, truly high risk. Thus for these types of programs, very high PPVs are desirable. Still, many patients who might be appropriate candidates for case management will be excluded from 27 selection, given the corresponding low sensitivities. It should be noted that even when cases are included that have probabilities as low as .4, the overall odds of these individuals being very high resource users next year are still much higher than random. In this case about 60% will be high risk next year compared to 5% of the population overall if selected at random. For individualized case management programs, having access to current and predicted resource use data for candidate individuals can be of real utility in setting priorities for inclusion. When there are more persons who would likely benefit than current program resources allow, these data could be used to help make an argument for expanding such resources on the basis of the potential return on investment (ROI). Using the approach described below (see the section entitled Adjusting Relative Weights to Compute Predicted Costs), you can assign a projected cost to each individual within your targeted high-risk group. Ordering this population by the difference between current and projected cost will quickly highlight those individuals for whom case management has the greatest potential. 28 APPENDICES Appendix 1. ACGs and EDCs Included in the acgPM ACGs 4220: 4-5 Other ADG Combinations, Age 1-17, 1+ Major ADGs 4330: 4-5 Other ADG Combinations, Age 18-44, 2+ Major ADGs 4420: 4-5 Other ADG Combinations, Age >44, 1 Major ADGs 4430: 4-5 Other ADG Combinations, Age >44, 2+ Major ADGs 4510: 6-9 Other ADG Combinations, Age 1-5, No Major ADGs 4520: 6-9 Other ADG Combinations, Age 1-5, 1+ Major ADGs 4610: 6-9 Other ADG Combinations, Age 6-17, No Major ADGs 4620: 6-9 Other ADG Combinations, Age 6-17, 1+ Major ADGs 4730: 6-9 Other ADG Combinations, Male, Age 18-34, 2+ Major ADGs 4830: 6-9 Other ADG Combinations, Female, Age 18-34, 2+ Major ADGs 4910: 6-9 Other ADG Combinations, Age >34, 0-1 Major ADGs 4920: 6-9 Other ADG Combinations, Age >34, 2 Major ADGs 4930: 6-9 Other ADG Combinations, Age >34, 3 Major ADGs 4940: 6-9 Other ADG Combinations, Age >34, 4+ Major ADGs 5010: 10+ Other ADG Combinations, Age 1-17 No Major ADGs 5020: 10+ Other ADG Combinations, Age 1-17, 1 Major ADGs 5030: 10+ Other ADG Combinations, Age 1-17, 2+ Major ADGs 5040: 10+ Other ADG Combinations, Age 18+, 0-1 Major ADGs 5050: 10+ Other ADG Combinations, Age 18+, 2 Major ADGs 5060: 10+ Other ADG Combinations, Age 18+, 3 Major ADGs 5070: 10+ Other ADG Combinations, Age 18+, 4+ Major ADGs 5320: Infants: 0-5 ADGs, 1+ Major ADGs 5330: Infants: 6+ ADGs, No Major 5340: Infants: 6+ ADGs, 1+ Major ADG Pregnancy w/out Delivery EDCs ADM04: Complications of Mechanical Devices ALL04: Asthma, w/o status asthmaticus ALL05: Asthma, WITH status asthmaticus ALL06: Disorders of the Immune System CAR03: Ischemic heart disease (excluding acute myocardial infarction) CAR04: Congenital heart disease CAR05: Congestive heart failure CAR06: Cardiac valve disorders CAR07: Cardiomyopathy CAR09: Cardiac arrhythmia CAR14: Hypertension, w/o major complications CAR15: Hypertension, WITH major complications END02: Osteoporosis END09: Type 1 Diabetes with major complicating condition 29 END08: Type 1 Diabetes w/o major complicating condition END07: Type 2 Diabetes with major complicating condition END06: Type 2 Diabetes w/o major complicating condition EYE13: Diabetic Retinopathy GAS02: Inflammatory bowel disease GAS05: Chronic liver diseases GAS06: Peptic ulcer disease GAS12: Chronic pancreatitis GSI08: Edema GSU11: Peripheral vascular disease GSU13: Aortic aneurysm GSU14: Gastrointestinal Obstruction/Perforation GTC01: Chromosomal anomalies GUR04: Prostatic hypertrophy HEM01: Hemolytic anemia HEM05: Aplastic anemia HEM06: Deep vein thrombosis HEM07: Hemophilia, coagulation Disorder INF04: HIV, AIDS MAL02: Low impact malignant neoplasms MAL03: High impact malignant neoplasms MAL04: Malignant neoplasms, breast MAL06: Malignant neoplasms, ovary MAL07: Malignant neoplasms, esophagus MAL08: Malignant neoplasms, kidney MAL09: Malignant neoplasms, liver and biliary tract MAL10: Malignant neoplasms, lung MAL11: Malignant neoplasms, lymphomas MAL12: Malignant neoplasms, colorectal MAL13: Malignant neoplasms, pancreas MAL14: Malignant neoplasms, prostate MAL15: Malignant neoplasms, stomach MAL16: Acute Leukemias MAL18: Malignant neoplasms, bladder MUS10: Fracture of neck of femur (hip) MUS14: Low back pain NUR05: Cerebrovascular disease NUR07: Seizure disorders NUR08: Multiple sclerosis NUR09: Muscular dystrophy NUR12: Quadriplegia and Paraplegia NUR15: Head Injury NUR16: Spinal Cord Injury/Disorders NUR17: Paralytic Syndromes, Other NUR18: Cerebral Palsy NUR19: Developmental disorders NUT02: Nutritional deficiencies 30 PSY01: Anxiety, neuroses PSY03: Tobacco abuse PSY05: Attention deficit disorder PSY07: Schizophrenia and affective psychosis PSY08: Personality disorders PSY09: Depression REC01: Cleft lip and palate REC03: Chronic ulcer of the skin REN01: Chronic renal failure RES03: Cystic fibrosis RES04: COPD RES09: Tracheostomy ACGs Included in the Three Resource Utilization Bands (RUBs) Reference Group ACG 0100 0200 0300 1100 1200 1600 5100 5110 5200 9900 ACG 0400 0500 0600 0900 1000 1300 1800 1900 2000 2100 2200 2300 2400 2500 2800 2900 3000 3100 3400 3900 4000 1711 1721 1731 1741 ACG 0700 0800 1400 1500 2600 2700 3200 3300 3500 3600 3700 3800 4100 4210 4310 4320 4410 4710 4720 4810 4820 5310 1751 1761 1771 ACG RUB Level 1 (Included in Intercept) ACG RUB Level 2 ACG RUB Level 3 31 Appendix 2. Summary of Performance Measures for Diagnostic Testing* “True” Condition “Screening Test” + - + - TP (True Positive) FN (False Negative) FP (False Positive) TN (True Negative) Predictive Value + = TP/ TP + FP Predictive Value - = TN/ FN + TN Sensitivity = TP/ TP + FN Specificity = TN/ FP + TN Receiver Operating Characteristic (ROC) = Function of Sensitivity vs. 1- Specificity at different screening thresholds (C Statistic = area under curve) * In the context of predictive modeling, a “+” for the “true” condition reflects a person being a member of the high-risk cohort (i.e., represents with the top 5% of costs in Year 2). The “+” for the “screening test” in this case would represent an individual with an acgPM probability score that is about the threshold considered actionable (e.g., a score that would place a person in the top half of 1% of the population. 32 Section 3 Improvements to the Johns Hopkins Expanded Diagnosis Clusters This section discusses Release 6.0 improvements to the Johns Hopkins expanded diagnosis clusters (EDCs) methodology, including: • refinements of the EDC taxonomy, and • enhanced reporting features. New users of the software are encouraged to review Chapter 13, “ ‘Dino-Clusters’: The Johns Hopkins Expanded Diagnosis Clusters (EDCs)” of the Version 5.0 Documentation and Application Manual for complete details of the EDC taxonomy, a discussion of the EDC output file, and technical specifications for customizing EDC reports. a. Overview Expanded diagnosis clusters (EDCs) were added to the ACG System in 2001 to provide the ability to partition populations into diagnosis-specific subgroups for a more complete understanding of case mix. Our intent was to condense the unwieldy list of ICD-9 codes into a much smaller number of clinically homogeneous clusters. As was the case for the original “diagnosis clusters,” our system places an emphasis on commonly occurring conditions treated primarily in ambulatory settings. The EDC system has undergone considerable refinement and now also includes less commonly occurring conditions, many of which may be treated in the hospital. In some instances, the original EDCs have been further subdivided to better reflect the effect of complicated illness, examples of which are presented on Table 1. Table 7. Subdivision of EDCs for Additional Clinical Specificity VERSION 5 EDC ALL02 Asthma CAR02 Hypertension END01 Diabetes Mellitus REVISED VERSION 6 EDCs ALL04 Asthma, w/o status asthmaticus ALL05 Asthma WITH status asthmaticus CAR14 Hypertension, w/o major complications CAR15 Hypertension, WITH major complications END06 Type 2 diabetes w/o major complicating conditions END07 Type 2 diabetes WITH major complicating conditions END08 Type 1 diabetes w/o major complicating conditions END09 Type 1 diabetes WITH major complicating conditions As these examples illustrate, in some instances the main refinement was to split the original category into complicated and uncomplicated subgroups. As a case in point, the asthma 33 EDC has been divided on the basis of the presence of status asthmaticus (i.e., an acute exacerbation of asthma). In the cardiology cluster, hypertension has been divided on the basis of the presence of a complicating condition. In other instances, the disease itself was further delineated, such as within the endocrine cluster where diabetes mellitus has been split into four categories—first by categorizing patients according to type 1 versus type 2 diabetes, and second according to the presence of a major, complicating comorbidity. (See Table A.1 in the Appendix to this chapter for a complete listing of these complicating conditions.) In addition to splitting existing EDCs, new categories have been added to the current software release. Table 2 provides a summary of new EDCs. In most instances, the additions within a given major EDC have been modest. For example, in the Administrative cluster, categories for transplant status and complications of mechanical devices were added. In the Cardiology cluster, a new category for acute myocardial infarction (CAR11) and Cardiac arrest/shock (CAR12) have been added. The malignancy and neurologic MEDC categories have been substantially expanded. All in all, 40 new EDC categories have been added and affect 16 of the 27 major EDC (MEDC) clusters, and several existing EDCs have been subdivided to provide additional clinical specificity. There are now a total of 236 EDC categories in ACG Release 6.0. For a sense of how these EDCs are distributed in the “real world,” their frequency of occurrence in a large under-65 population (2 million covered lives) is provided in Appendix A.2. 34 Table 8. Supplemental EDCs by MEDC Category MEDC/EDC CATEGORY Administrative ADM03 DESCRIPTION ADM04 Transplant status Complications of mechanical devices ALL06 Disorders of the immune system MEDC/EDC CATEGORY Malignancies (continued) MAL10 MAL11 Allergy MAL12 MAL13 MAL14 MAL15 Cardiovascular CAR11 CAR12 Disorders of lipoid metabolism Acute Myocardial Infarction Eye EYE13 GastrointestinalHepatic GAS11 GAS12 General Surgery GSU13 GSU14 Hematologic HEM06 HEM07 Infections HEM08 Malignancies MAL04 MAL05 MAL06 MAL07 MAL08 MAL09 b. Diabetic retinopathy Acute pancreatitis Chronic pancreatitis Aortic aneurysm Gastrointestinal obstruction/perforation Aplastic anemia Deep vein thrombosis Septicemia Malignant neoplasm, breast Malignant neoplasm, cervix, uterus Malignant neoplasm, ovary Malignant neoplasm, esophagus Malignant neoplasm, kidney Malignant neoplasm, liver and biliary tract MAL16 MAL18 Musculoskeletal MUS16 Neurologic NUR12 NUR15 NUR16 NUR17 NUR18 NUR19 Psychosocial PSY09 Renal REN03 REN04 Respiratory DESCRIPTION Malignant neoplasm, lung Malignant neoplasm, lymphomas Malignant neoplasm, colorectal Malignant neoplasm, pancreas Malignant neoplasm, prostate Malignant neoplasm, stomach Acute leukemia Malignant neoplasm, bladder Amputation status Quadriplegia and paraplegia Head injury Spinal cord injury/disorders Paralytic syndromes, other Cerebral palsy Developmental disorder Depression Acute renal failure Nephritis/nephrosis RES08 RES09 Pulmonary embolism Tracheostomy RES10 Respiratory arrest SKN18 Benign neoplasm of skin and subcutaneous tissues Skin New Reporting Features The EDC reporting capabilities of ACG Release 6.0 have been significantly enhanced to facilitate their easy implementation within your organization. The current automatically generated reports include EDC distributions, tables combining disease-specific EDCs and the morbidity-class, as well as age/sex-adjusted comparison of EDC distributions across populations. 35 EDCxRUB Reports A series of reports combining the disease-specific EDC and ACG methodologies provides managers with information that should be useful in better targeting their care management programs. Reports are generated first by major EDC (or MEDC) level to provide a summary overview, and then this set of summary tables is generated for each specific diagnosis cluster. Examples of the new reports are provided in Tables 3 and 4. Table 3: Percent distribution of each co-morbidity level within EDC (Samples) RUB-1 RUB-2 RUB-3 RUB-4 RUB-5 EDC Very Low Low Average High Very High --------------------------------- --------- --------- --------- --------- --------ADM01:General medical exam 19.8 32.9 39.9 6.2 1.3 ADM02:Surgical aftercare 4.7 19.3 46.6 18.9 10.4 ADM03:Transplant status 3.8 7.7 32.9 26.6 29.1 ADM04:Complications of mechanical 0.0 10.3 32.4 25.5 31.8 ALL01:Allergic reactions 0.0 36.2 53.6 8.5 1.6 ALL03:Allergic rhinitis 0.0 34.5 56.0 8.2 1.3 ALL04:Asthma, w/o status asthmati 0.0 23.6 63.2 10.7 2.5 ALL05:Asthma, with status asthmat 0.0 20.9 58.0 15.6 5.4 ALL06:Disorders of the immune sys 0.0 6.5 47.6 25.5 20.4 CAR01:Cardiovascular signs and sy 0.0 14.5 64.2 15.2 6.1 CAR03:Ischemic heart disease (exc 0.0 0.5 55.7 27.3 16.6 CAR04:Congenital heart disease 0.0 17.9 45.9 23.9 12.4 CAR05:Congestive heart failure 0.0 0.4 36.6 31.1 31.9 CAR06:Cardiac valve disorders 0.0 7.6 59.1 22.2 11.1 CAR07:Cardiomyopathy 0.0 2.2 43.8 30.1 23.9 CAR08:Heart murmur 12.3 25.8 44.5 11.9 5.4 CAR09:Cardiac arrhythmia 0.0 3.7 58.4 24.5 13.3 CAR10:Generalized atherosclerosis 0.0 7.0 43.7 25.4 23.9 CAR11:Disorders of lipoid metabol 0.0 17.3 68.0 10.4 4.2 CAR12:Acute myocardial infarction 0.0 0.2 21.3 39.3 39.2 CAR13:Cardiac arrest, shock 0.0 5.4 19.2 31.2 44.2 CAR14:Hypertension, w/o major com 0.0 20.6 64.7 10.2 4.5 CAR15:Hypertension, with major co 0.0 4.1 55.4 24.1 16.3 Each row in the tables represents a separate MEDC (or EDC) category, and the columns array individuals within a particular MEDC (or EDC) into five (from very low to very high) morbidity groupings that we term resource utilization bands (RUBs). RUB categories are based on ACG assignments (see Chapter 8, “Calibrating ACGs for Intended Use: ACG Weights, Resource Utilization Bands, and Carve-Outs,” in the Release 5.0 Documentation and Application Manual). The first part of this two-part table (Table 3) presents the percentage distribution for each EDCxRUB comorbidity level, and the second (Table 4) presents an estimate of each group’s expected relative resource use. Focusing on the EDC for general medical exam, ADM01, you see that the first row of Table 3 shows 19.8% of users with this EDC fell into RUB-1 or a very low resource group, 32.9% fell into the low resource RUB-2, 39.9% fell into 36 average resource RUB-3, and so on. Looking at the same row in Table 4, you see that the anticipated resource use for such individuals is ranges from a low of 0.19 to a high of 24.76 for those in the highest resource group. Resource estimates provided in these tables are based on nationally representative ACG weights built into the software (see the “Using the Available Relative Value Weights” section for additional details on concurrent weights and RUB assignments included as part of Release 6.0). These tables help to illustrate the variability of costs within disease categories and will be useful to managers for better understanding resource use. Generally it is not necessarily all individuals with selected diseases who are expensive; rather, it is individuals with multiple comorbidities who consume most of the health care resources. Table 4: Estimated Concurrent Resource Use by RUB by EDC (Samples) RUB-1 RUB-2 RUB-3 RUB-4 RUB-5 EDC Very Low Low Average High Very High --------------------------------- --------- --------- --------- --------- --------ADM01:General medical exam 0.19 0.54 1.97 7.12 24.76 ADM02:Surgical aftercare 0.20 0.63 2.31 7.94 27.30 ADM03:Transplant status 0.20 0.65 2.39 8.23 29.89 ADM04:Complications of mechanical 0.00 0.69 2.35 7.97 29.84 ALL01:Allergic reactions 0.00 0.54 2.07 7.49 25.41 ALL03:Allergic rhinitis 0.00 0.54 2.13 7.43 25.40 ALL04:Asthma, w/o status asthmati 0.00 0.62 2.03 7.43 26.10 ALL05:Asthma, with status asthmat 0.00 0.62 2.13 7.50 28.23 ALL06:Disorders of the immune sys 0.00 0.74 2.39 7.71 29.63 CAR01:Cardiovascular signs and sy 0.00 0.60 2.43 7.96 26.56 CAR03:Ischemic heart disease (exc 0.00 0.68 2.25 8.12 25.35 CAR04:Congenital heart disease 0.00 0.73 2.20 7.11 25.56 CAR05:Congestive heart failure 0.00 0.81 2.62 8.30 28.83 CAR06:Cardiac valve disorders 0.00 0.56 2.42 7.86 27.10 CAR07:Cardiomyopathy 0.00 0.73 2.37 8.23 28.69 CAR08:Heart murmur 0.21 0.64 2.22 7.20 23.05 CAR09:Cardiac arrhythmia 0.17 0.61 2.37 8.07 25.82 CAR10:Generalized atherosclerosis 0.00 0.46 2.47 8.23 27.06 CAR11:Disorders of lipoid metabol 0.00 0.49 2.29 8.17 25.14 CAR12:Acute myocardial infarction 0.00 0.82 1.85 7.87 26.28 CAR13:Cardiac arrest, shock 0.00 0.62 2.12 7.74 27.84 CAR14:Hypertension, w/o major com 0.00 0.48 2.28 8.16 25.75 CAR15:Hypertension, with major co 0.00 0.62 2.35 8.31 27.40 Standardized Morbidity Ratios The current release generates a series of age/sex standardized EDC-based “morbidity ratio” tables to assist with population-level profiling based on a user-defined population stratifier that can be provided by means of the software’s input file (see the “Installation and Usage Guide” for the technical details of implementing this feature). Separate reports are generated for each population group defined by the user. Such information can help practitioners and managers understand which specific conditions within a subgroup of interest are more or less common (beyond statistical chance) than the overall population average. As illustrated in Table 5, summary statistics generated for each group in this case, by MEDC category, include 37 • observed prevalence rates, • age/sex-expected prevalence, • standardized morbidity ratio (SMR), as well as • low and high indicators for statistical significance at the 95% confidence interval. Table 5. Age/sex-adjusted Comparison of Disease Distributions across Populations ***Observed to Expected Standardized Morbidity Ratio by MEDC*** Population: ALL Number of persons=2,141,852 Major EDC Administrative.................... Allergy........................... Cardiovascular.................... Dental............................ Ears, Nose, Throat................ Endocrine......................... Eye............................... Female Reproductive............... Gastrointestinal/Hepatic.......... General Signs and Symptoms........ General Surgery................... Genetic........................... Genito-urinary.................... Hematologic....................... Infections........................ Malignancies...................... Musculoskeletal................... Neurologic........................ Nutrition......................... Psychosocial...................... Reconstructive.................... Renal............................. Respiratory....................... Rheumatologic..................... Skin.............................. Toxic Effects..................... Unassigned........................ Observed Age-Sex Standardized Prevalence Expected Morbidity 95% per 1000 Prevalence Ratio Confidence Interval Population per 1000 (SMR) (Low) (High) --------- --------- --------- --------- --------284.43 64.19 72.79 7.69 216.82 29.74 120.49 85.97 56.26 69.65 99.12 0.25 47.42 10.41 37.95 10.21 180.73 58.19 10.87 40.73 27.35 5.16 140.57 11.67 150.22 5.52 98.88 284.43 64.19 72.79 7.69 216.82 29.74 120.49 85.97 56.26 69.65 99.12 0.25 47.42 10.41 37.95 10.21 180.73 58.19 10.87 40.73 27.35 5.16 140.57 11.67 150.22 5.52 98.88 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 0.997 0.995 0.995 0.985 0.997 0.992 0.996 0.995 0.994 0.995 0.996 0.915 0.994 0.987 0.993 0.987 0.997 0.994 0.987 0.993 0.992 0.981 0.996 0.988 0.997 0.982 0.996 1.003 1.005 1.005 1.015 1.003 1.008 1.004 1.005 1.006 1.005 1.004 1.085 1.006 1.013 1.007 1.013 1.003 1.006 1.013 1.007 1.008 1.019 1.004 1.012 1.003 1.018 1.004 A Note on Customizing These Reports The technical specifications for creating these tables on other population subgroups and/or based on locally calibrated cost data are provided in “Section d. Dino-Cluster Applications/Approaches” of Chapter 13 in the Release 5.0 Documentation and Application Guide. Although these tables are built into the software to allow quick implementation, to maximize the usefulness of this type of information it is recommended that they be re-created and calibrated to local data. 38 Appendix A.1 Table A.1: List of Complicating Conditions Used to Split Diabetes EDCs ICD-9 Code 2501 25010 25011 25012 25013 2502 25020 25021 25022 25023 2503 25030 25031 25032 25033 2504 25040 25041 25042 25043 410 4100 41000 41001 41002 4101 41010 41011 41012 4102 41020 41021 41022 4103 41030 41031 41032 4104 41040 41041 41042 Description DIABETES W KETOACIDOSIS* DMII KETO NT ST UNCNTRLD DMI KETO NT ST UNCNTRLD DMII KETOACD UNCONTROLD DMI KETOACD UNCONTROLD DIAB W HYPEROSMOLAR COMA* DMII HPRSM NT ST UNCNTRL DMI HPRSM NT ST UNCNTRLD DMII HPROSMLR UNCONTROLD DMI HPROSMLR UNCONTROLD DIABETES WITH COMA NEC* DMII O CM NT ST UNCNTRLD DMI O CM NT ST UNCNTRLD DMII OTH COMA UNCONTROLD DMI OTH COMA UNCONTROLD DIAB W RENAL MANIFEST* DMII RENL NT ST UNCNTRLD DMI RENL NT ST UNCNTRLD DMII RENAL UNCNTRLD DMI RENAL UNCNTRLD ACUTE MYOCARDIAL INFARCT* AMI ANTEROLATERAL WALL* AMI ANTEROLATERAL,UNSPEC AMI ANTEROLATERAL, INIT AMI ANTEROLATERAL,SUBSEQ AMI ANTERIOR WALL NEC* AMI ANTERIOR WALL,UNSPEC AMI ANTERIOR WALL, INIT AMI ANTERIOR WALL,SUBSEQ AMI INFEROLATERAL WALL* AMI INFEROLATERAL,UNSPEC AMI INFEROLATERAL, INIT AMI INFEROLATERAL,SUBSEQ AMI INFEROPOSTERIOR WALL* AMI INFEROPOST, UNSPEC AMI INFEROPOST, INITIAL AMI INFEROPOST, SUBSEQ AMI INFERIOR WALL NEC* AMI INFERIOR WALL,UNSPEC AMI INFERIOR WALL, INIT AMI INFERIOR WALL,SUBSEQ 39 ICD-9 Code 4105 41050 41051 41052 4106 41060 41061 41062 4107 41070 41071 41072 4108 41080 41081 41082 4109 41090 41091 41092 411 4110 4111 4118 41181 41189 412 413 4130 4131 4139 414 4140 41400 41401 41402 41403 41404 41405 4141 41410 41411 41419 4148 Description AMI LATERAL WALL NEC* AMI LATERAL NEC, UNSPEC AMI LATERAL NEC, INITIAL AMI LATERAL NEC, SUBSEQ TRUE POSTERIOR INFARCT* TRUE POST INFARCT,UNSPEC TRUE POST INFARCT, INIT TRUE POST INFARCT,SUBSEQ SUBENDOCARDIAL INFARCT* SUBENDO INFARCT, UNSPEC SUBENDO INFARCT, INITIAL SUBENDO INFARCT, SUBSEQ MYOCARDIAL INFARCT NEC* AMI NEC, UNSPECIFIED AMI NEC, INITIAL AMI NEC, SUBSEQUENT MYOCARDIAL INFARCT NOS* AMI NOS, UNSPECIFIED AMI NOS, INITIAL AMI NOS, SUBSEQUENT OTH AC ISCHEMIC HRT DIS* POST MI SYNDROME INTERMED CORONARY SYND AC ISCHEMIC HRT DIS NEC* CORONARY OCCLSN W/O MI AC ISCHEMIC HRT DIS NEC OLD MYOCARDIAL INFARCT ANGINA PECTORIS* ANGINA DECUBITUS PRINZMETAL ANGINA ANGINA PECTORIS NEC/NOS OTH CHR ISCHEMIC HRT DIS* CORONARY ATHEROSCLEROSIS* COR ATH UNSP VSL NTV/GFT CRNRY ATHRSCL NATVE VSSL CRN ATH ATLG VN BPS GRFT CRN ATH NONATLG BLG GRFT COR ATH ARTRY BYPAS GRFT COR ATH BYPASS GRAFT NOS ANEURYSM OF HEART* ANEURYSM, HEART (WALL) CORONARY VESSEL ANEURYSM ANEURYSM OF HEART NEC CHR ISCHEMIC HRT DIS NEC 40 ICD-9 Code 4149 581 5810 5811 5812 5813 5818 58181 58189 5819 582 5820 5821 5822 5824 5828 58281 58289 5829 583 5830 5831 5832 5834 5836 5837 5838 58381 58389 5839 584 5845 5846 5847 5848 5849 585 586 V56 V560 V561 V562 V568 Description CHR ISCHEMIC HRT DIS NOS NEPHROTIC SYNDROME* NEPHROTIC SYN, PROLIFER EPIMEMBRANOUS NEPHRITIS MEMBRANOPROLIF NEPHROSIS MINIMAL CHANGE NEPHROSIS NEPHROTIC SYN W OTH LES* NEPHROTIC SYN IN OTH DIS NEPHROTIC SYNDROME NEC NEPHROTIC SYNDROME NOS CHRONIC NEPHRITIS* CHR PROLIFERAT NEPHRITIS CHR MEMBRANOUS NEPHRITIS CHR MEMBRANOPROLIF NEPHR CHR RAPID PROGR NEPHRIT CHR NEPHRITIS W OTH LES* CHR NEPHRITIS IN OTH DIS CHRONIC NEPHRITIS NEC CHRONIC NEPHRITIS NOS NEPHRITIS NOS* PROLIFERAT NEPHRITIS NOS MEMBRANOUS NEPHRITIS NOS MEMBRANOPROLIF NEPHR NOS RAPIDLY PROG NEPHRIT NOS RENAL CORT NECROSIS NOS NEPHR NOS/MEDULL NECROS NEPHRITIS NOS W OTH LES* NEPHRITIS NOS IN OTH DIS NEPHRITIS NEC NEPHRITIS NOS ACUTE RENAL FAILURE* LOWER NEPHRON NEPHROSIS AC RENAL FAIL, CORT NECR AC REN FAIL, MEDULL NECR AC RENAL FAILURE NEC ACUTE RENAL FAILURE NOS CHRONIC RENAL FAILURE RENAL FAILURE NOS DIALYSIS ENCOUNTER* RENAL DIALYSIS ENCOUNTER FT/ADJ XTRCORP DIAL CATH FIT/ADJ PERIT DIAL CATH DIALYSIS ENCOUNTER, NEC 41 Appendix A.2 Table A.2: Major Expanded Diagnosis Clusters and their Component Expanded Diagnosis Clusters Number and Prevelance per Thousand of Major Expanded Diagnosis Clusters and their Component Expanded Diagnosis Clusters EDC Description No. No. Persons Persons per 1000 Population ADM Administrative.................................... ADM01 General medical exam ADM02 Surgical aftercare ADM03 Transplant status ADM04 Complications of mechanical devices 609207 591820 33143 821 3163 284.43 276.31 15.47 0.38 1.48 ALL Allergy........................................... ALL01 Allergic reactions ALL03 Allergic rhinitis ALL04 Asthma, w/o status asthmaticus ALL05 Asthma, with status asthmaticus ALL06 Disorders of the immune system 137496 23434 80055 49058 4303 1510 64.19 10.94 37.38 22.90 2.01 0.70 CAR Cardiovascular.................................... CAR01 Cardiovascular signs and symptoms CAR03 Ischemic heart disease (excluding acute myocard CAR04 Congenital heart disease CAR05 Congestive heart failure CAR06 Cardiac valve disorders CAR07 Cardiomyopathy CAR08 Heart murmur CAR09 Cardiac arrhythmia CAR10 Generalized atherosclerosis CAR11 Disorders of lipoid metabolism CAR12 Acute myocardial infarction CAR13 Cardiac arrest, shock CAR14 Hypertension, w/o major complications CAR15 Hypertension, with major complications 155912 18491 16628 3192 2642 5142 1786 3113 11709 2182 49358 2692 276 82457 5674 72.79 8.63 7.76 1.49 1.23 2.40 0.83 1.45 5.47 1.02 23.04 1.26 0.13 38.50 2.65 DEN Dental............................................ DEN01 Disorders of mouth DEN02 Disorders of teeth DEN03 Gingivitis DEN04 Stomatitis 16467 5599 7324 641 3349 7.69 2.61 3.42 0.30 1.56 EAR Ears, Nose, Throat................................ EAR01 Otitis media EAR02 Tinnitus EAR03 Temporomandibular joint disease EAR04 Foreign body in ears, nose, or throat EAR05 Deviated nasal septum EAR06 Otitis externa EAR07 Wax in ear EAR08 Deafness, hearing loss EAR09 Chronic pharyngitis and tonsillitis EAR10 Epistaxis EAR11 Acute upper respiratory tract infection 464405 174138 3029 5405 2427 4266 21013 19863 11679 8961 4477 335295 216.82 81.30 1.41 2.52 1.13 1.99 9.81 9.27 5.45 4.18 2.09 156.54 END Endocrine......................................... END02 Osteoporosis END03 Short stature END04 Thyroid disease END05 Other endocrine disorders END06 Type 2 diabetes, w/o complication END07 Type 2 diabetes w/complications END08 Type 1 diabetes, w/o complication END09 Type 1 diabetes w/complications 63700 2300 0 25859 6997 19985 2538 6948 2105 29.74 1.07 0.00 12.07 3.27 9.33 1.18 3.24 0.98 258070 48584 1133 7868 8569 116028 120.49 22.68 0.53 3.67 4.00 54.17 EYE Eye............................................... EYE01 Ophthalmic signs and symptoms EYE02 Blindness EYE03 Retinal disorders (excluding diabetic retinopat EYE04 Disorders of the eyelid and lacrimal duct EYE05 Refractive errors 42 EYE06 EYE07 EYE08 EYE09 EYE10 EYE11 EYE12 EYE13 Cataract, aphakia Conjunctivitis, keratitis Glaucoma Infections of eyelid Foreign body in eye Strabismus, amblyopia Traumatic injuries of eye Diabetic retinopathy 10316 55252 14709 9893 4990 9393 9635 3002 4.82 25.80 6.87 4.62 2.33 4.39 4.50 1.40 FRE Female Reproductive............................... FRE01 Pregnancy and delivery, uncomplicated FRE02 Female genital symptoms FRE03 Endometriosis FRE04 Pregnancy and delivery with complications FRE05 Female infertility FRE06 Abnormal pap smear FRE07 Ovarian cyst FRE08 Vaginitis, vulvitis, cervicitis FRE09 Menstrual disorders FRE10 Contraception FRE11 Menopausal symptoms FRE12 Utero-vaginal prolapse 184131 36641 24750 4517 24972 5620 19224 5972 39660 38792 33246 22311 4599 85.97 17.11 11.56 2.11 11.66 2.62 8.98 2.79 18.52 18.11 15.52 10.42 2.15 GAS Gastrointestinal/Hepatic.......................... GAS01 Gastrointestinal signs and symptoms GAS02 Inflammatory bowel disease GAS03 Constipation GAS04 Acute hepatitis GAS05 Chronic liver disease GAS06 Peptic ulcer disease GAS07 Diarrhea GAS08 Gastroesophageal reflux GAS09 Irritable bowel syndrome GAS10 Diverticular disease of colon GAS11 Acute pancreatitis GAS12 Chronic pancreatitis 120499 16983 4025 8568 1940 1820 24892 45645 26499 8755 6894 855 431 56.26 7.93 1.88 4.00 0.91 0.85 11.62 21.31 12.37 4.09 3.22 0.40 0.20 GSI General Signs and Symptoms........................ GSI01 Nonspecific signs and symptoms GSI02 Chest pain GSI03 Fever GSI04 Syncope GSI05 Nausea, vomiting GSI06 Debility and undue fatigue GSI07 Lymphadenopathy GSI08 Edema 149173 41431 48997 20183 6150 14094 22794 7574 5185 69.65 19.34 22.88 9.42 2.87 6.58 10.64 3.54 2.42 GSU General Surgery................................... GSU01 Anorectal conditions GSU02 Appendicitis GSU03 Benign and unspecified neoplasm GSU04 Cholelithiasis, cholecystitis GSU05 External abdominal hernias, hydroceles GSU06 Chronic cystic disease of the breast GSU07 Other breast disorders GSU08 Varicose veins of lower extremities GSU09 Nonfungal infections of skin and subcutaneous t GSU10 Abdominal pain GSU11 Peripheral vascular disease GSU12 Burns--1st degree GSU13 Aortic aneurysm GSU14 Gastrointestinal obstruction/perforation 212307 23172 2340 49680 6494 9671 16834 14648 3837 47125 72252 2703 792 357 4324 99.12 10.82 1.09 23.19 3.03 4.52 7.86 6.84 1.79 22.00 33.73 1.26 0.37 0.17 2.02 GTC Genetic........................................... GTC01 Chromosomal anomalies 538 538 0.25 0.25 GUR Genito-urinary.................................... GUR01 Vesicoureteral reflux GUR02 Undescended testes GUR03 Hypospadias, other penile anomalies GUR04 Prostatic hypertrophy GUR05 Stricture of urethra GUR06 Urinary symptoms GUR07 Other male genital disease GUR08 Urinary tract infections GUR09 Renal calculi GUR10 Prostatitis 101573 752 613 480 8538 1326 30256 11967 50656 6768 5553 47.42 0.35 0.29 0.22 3.99 0.62 14.13 5.59 23.65 3.16 2.59 HEM Hematologic....................................... HEM01 Hemolytic anemia 22305 1007 10.41 0.47 43 HEM02 HEM03 HEM04 HEM05 HEM06 HEM07 Iron deficiency, other deficiency anemias Thrombophlebitis Neonatal jaundice Aplastic anemia Deep vein thrombosis Hemophilia, coagulation disorder 15175 2611 2247 349 1511 968 7.08 1.22 1.05 0.16 0.71 0.45 INF Infections........................................ INF01 Tuberculosis infection INF02 Fungal infections INF03 Infectious mononucleosis INF04 HIV, AIDS INF05 Sexually transmitted diseases INF06 Viral syndromes INF07 Lyme disease INF08 Septicemia 81276 523 6315 3438 826 13725 55597 819 2688 37.95 0.24 2.95 1.61 0.39 6.41 25.96 0.38 1.25 MAL Malignancies...................................... MAL01 Malignant neoplasms of the skin MAL02 Low impact malignant neoplasms MAL03 High impact malignant neoplasms MAL04 Malignant neoplasms, breast MAL05 Malignant neoplasms, cervix, uterus MAL06 Malignant neoplasms, ovary MAL07 Malignant neoplasms, esophagus MAL08 Malignant neoplasms, kidney MAL09 Malignant neoplasms, liver and biliary tract MAL10 Malignant neoplasms, lung MAL11 Malignant neoplasms, lymphomas MAL12 Malignant neoplasms, colorectal MAL13 Malignant neoplasms, pancreas MAL14 Malignant neoplasms, prostate MAL15 Malignant neoplasms, stomach MAL16 Acute leukemia MAL18 Malignant neoplasms, bladder 21861 5542 3489 2949 5040 1434 552 94 353 111 649 1750 1102 92 1265 86 390 579 10.21 2.59 1.63 1.38 2.35 0.67 0.26 0.04 0.16 0.05 0.30 0.82 0.51 0.04 0.59 0.04 0.18 0.27 MUS Musculoskeletal................................... MUS01 Musculoskeletal signs and symptoms MUS02 Acute sprains and strains MUS03 Degenerative joint disease MUS04 Fractures (excluding digits) MUS05 Torticollis MUS06 Kyphoscoliosis MUS07 Congenital hip dislocation MUS08 Fractures and dislocations/digits only MUS09 Joint disorders, trauma related MUS10 Fracture of neck of femur (hip) MUS11 Congenital anomalies of limbs, hands, and feet MUS12 Acquired foot deformities MUS13 Cervical pain syndromes MUS14 Low back pain MUS15 Bursitis, synovitis, tenosynovitis MUS16 Amputation status 387105 101099 93832 23198 31563 1948 4386 341 9461 51613 581 4273 12711 50260 109842 67999 1041 180.73 47.20 43.81 10.83 14.74 0.91 2.05 0.16 4.42 24.10 0.27 2.00 5.93 23.47 51.28 31.75 0.49 NUR Neurologic........................................ NUR01 Neurologic signs and symptoms NUR02 Headaches NUR03 Peripheral neuropathy, neuritis NUR04 Vertiginous syndromes NUR05 Cerebrovascular disease NUR06 Parkinson's disease NUR07 Seizure disorder NUR08 Multiple sclerosis NUR09 Muscular dystrophy NUR10 Sleep problems NUR11 Dementia and delirium NUR12 Quadriplegia and paraplegia NUR15 Head injury NUR16 Spinal cord injury/disorders NUR17 Paralytic syndromes, other NUR18 Cerebral palsy NUR19 Developmental disorder 124627 4697 51219 26715 20154 4141 815 9071 2387 497 7872 422 751 6388 2077 989 1108 3018 58.19 2.19 23.91 12.47 9.41 1.93 0.38 4.24 1.11 0.23 3.68 0.20 0.35 2.98 0.97 0.46 0.52 1.41 NUT Nutrition......................................... NUT01 Failure to thrive NUT02 Nutritional deficiencies NUT03 Obesity 23286 4397 2327 16765 10.87 2.05 1.09 7.83 PSY Psychosocial...................................... PSY01 Anxiety, neuroses 87242 50088 40.73 23.39 44 PSY02 PSY03 PSY04 PSY05 PSY06 PSY07 PSY08 PSY09 Substance use Tobacco abuse Behavior problems Attention deficit disorder Family and social problems Schizophrenia and affective psychosis Personality disorders Depression 6473 10391 2418 12015 2354 2496 785 17849 3.02 4.85 1.13 5.61 1.10 1.17 0.37 8.33 REC Reconstructive.................................... REC01 Cleft lip and palate REC02 Lacerations REC03 Chronic ulcer of the skin REC04 Burns--2nd and 3rd degree 58571 393 52124 2112 4582 27.35 0.18 24.34 0.99 2.14 REN Renal............................................. REN01 Chronic renal failure REN02 Fluid/electrolyte disturbances REN03 Acute renal failure REN04 Nephritis, nephrosis 11047 1286 9136 398 1205 5.16 0.60 4.27 0.19 0.56 RES Respiratory....................................... RES01 Respiratory signs and symptoms RES02 Acute lower respiratory tract infection RES03 Cystic fibrosis RES04 Emphysema, chronic bronchitis, COPD RES05 Cough RES06 Sleep apnea RES07 Sinusitis RES08 Pulmonary embolism RES09 Tracheostomy RES10 Respiratory arrest 301082 24552 141625 363 10158 29636 4636 142549 494 216 4268 140.57 11.46 66.12 0.17 4.74 13.84 2.16 66.55 0.23 0.10 1.99 RHU Rheumatologic..................................... RHU01 Autoimmune and connective tissue diseases RHU02 Gout RHU03 Arthropathy RHU04 Raynaud's syndrome 24989 10331 4274 11170 908 11.67 4.82 2.00 5.22 0.42 321746 55057 69204 1289 34217 4267 14670 43120 6316 38376 16057 20999 5535 9158 1628 3247 9665 26155 43002 150.22 25.71 32.31 0.60 15.98 1.99 6.85 20.13 2.95 17.92 7.50 9.80 2.58 4.28 0.76 1.52 4.51 12.21 20.08 TOX Toxic Effects..................................... TOX01 Toxic effects of nonmedicinal agents TOX02 Adverse effects of medicinal agents 11831 4877 7118 5.52 2.28 3.32 UDC Unassigned........................................ UDC00 Unassigned diagnosis code 211794 211794 98.88 98.88 SKN Skin.............................................. SKN01 Contusions and abrasions SKN02 Dermatitis and eczema SKN03 Keloid SKN04 Acne SKN05 Disorders of sebaceous glands SKN06 Sebaceous cyst SKN07 Viral warts and molluscum contagiosum SKN08 Other inflammatory conditions of skin SKN09 Exanthems SKN10 Skin keratoses SKN11 Dermatophytoses SKN12 Psoriasis SKN13 Disease of hair and hair follicles SKN14 Pigmented nevus SKN15 Scabies and pediculosis SKN16 Diseases of nail SKN17 Other skin disorders SKN18 Benign neoplasm of skin and subcutaneous tissue 45 Section 4 Using the Software-provided ACG Relative Value Weights With Release 6.0 of the ACG software, weights are for the first time being made available as part of the ACG output stream. Weights is the term that we have traditionally used to represent measures of the level of resource use that are associated with an ACG assignment. Essentially they represent an average resource use “expectation” for a particular ACG category and are generally based on local data. Weights can be expressed as actual dollars expected to be spent over a period of time or as relative values (the ratio of expected use in that ACG to an overall population mean). This section discusses the use of new internal relative value weights and the conversion of these scores to dollar amounts. Readers are especially encouraged to review the section on the “rescaling process” before using these weights. For an extensive discussion on the computation of weights and calibration of local data, see Chapter 8, “Calibrating ACGs for Intended Use: ACG Weights, Resource Utilization Bands, and Carveouts,” in the Release 5.0 Documentation and Application Manual). a. Concurrent ACG Weights A fixed set of concurrent ACG weights is now available as part of the software output file (see Installation and Usage Guide for instructions on how to turn on this option). These are relative weights, i.e., relative to a population mean, and are standardized to a mean of 1.0. The software-supplied weights may be considered a national reference or benchmark for comparisons with locally calibrated ACG weights. However, in some instances (e.g., for those with limited or no cost data), these weights may also be used as a reasonable proxy for local cost data. Table 2 at the end of this section is a complete listing of ACGs and their corresponding nationally representative concurrent ACG weight. (See the additional discussion below about the importance of rescaling so that dollars are not over- or under-predicted). Our experience indicates that concurrent or retrospective ACG weights, especially when expressed as relative values, have remarkable stability. Where differences in ACG weights across plans are present, it is almost universally attributable to differences in covered services reflected by different benefit levels. The new software-provided concurrent weights were developed from a nationally representative database comprising approximately two million lives with comprehensive benefit coverage. 47 Ideally, ACG weights should be calculated from plan-specific local data to account most accurately for benefit levels and area practice patterns. The reference population (on which the weights are developed) should be as similar as possible to the assessment population to which the weights are applied. However, and as noted, in the absence of local cost data the softwareprovided internal weights may prove useful for calculating reasonably representative profiling statistics (see Chapter 12, “ACG Risk Adjustment and Provider Profiling,” in the Release 5.0 Documentation and Application Manual). b. Converting Scores to Dollars Both the ACG concurrent weights and the new acgPM Predicted Risk Index (PRI, see Section 2 of this document) are expressed as relative values, where the mean is centered at 1.0. Individuals with scores higher than 1.0 are more expensive than average whereas those with scores less than 1.0 are less expensive than average. Such relative indices can easily be converted to dollar amounts by multiplying by the underlying mean of the population to which the risk adjustment values will be applied. Before converting scores to dollar amounts, it is important to rescale the data so as to account for differences between the reference population (in this case the Johns Hopkins nationally representative database comprising over two million covered lives) and the population to which the weights are applied (e.g., your population of interest). Rescaling is necessary to assure that the underlying mean of the predictions is 1.0. A similar process is undertaken when you use your own reference population, when it has somewhat different characteristics or circumstances (e.g., it is from a previous time period, or benefit coverage is somewhat different). Unless rescaling is done, resource use (or payments) may be over- or under-predicted. Table 1 below and the accompanying discussion provide a simplified example for a population with only 12 members. c. The Rescaling Process Step 1: Compute population mean weight. Compute a separate grand mean for each of the weights (either concurrent ACG weights or the acgPM PRI) generated for your population 48 (the observations represent individuals). The mean for this example is shown in Table 1 at the bottom of column B. Step 2: Apply weighting factor. Divide each individual weight by the rescaling factor (i.e., the mean) that you computed in Step 1. The result is the rescaled relative weight (column C). Step 3: Compute population mean cost. For the same population on which the weights were based, compute the mean cost for the current data year. For this example, the mean cost was $1,265.11. Step 4: Compute cost. Multiply the rescaled relative weights generated for each member of the population (Column C) by the average population cost generated from Step 3 to calculate an estimated individual cost (column D). Table 1: Estimating Costs in a Sample of Cases A B C D Relative Rescaled Estimated Observation Weight Weight Cost 1 0.185 0.171 $216.36 2 0.291 0.268 $339.61 3 0.387 0.357 $451.64 4 0.457 0.422 $533.33 5 0.541 0.499 $631.33 6 0.609 0.562 $711.58 7 0.696 0.642 $812.58 8 0.842 0.777 $982.84 9 1.025 0.946 $1,196.68 10 1.293 1.194 $1,510.19 11 1.892 1.746 $2,209.38 12 4.783 4.415 $5,585.78 1.000 $1,265.11 1.083 Mean The rescaling factor functions as a summary case-mix index for understanding how the rating population (e.g., your local population) compares to the development data (JHU’s nationally representative database). The interpretation of this factor is analogous to how one interprets both relative weights and profiling indicators. If the rescaling factor is greater than 1.0 49 (as it was in the example), then your population is sicker; if the factor is less than 1.0, then your population is healthier than the reference population. d. Adjustments for Inflation If you are going to use the scores for predicting future expenditures it may be appropriate to inflation-adjust these values. Based on Bureau of Labor Statistics results, for the calendar year 2002 medical care costs rose by approximately 4.7% over the previous year (see http://data.bls.gov). In the preceding example, if you were going to apply this inflation adjustment, you would multiply the mean cost computed in Step 3 by 1.047 to reflect inflation. For this example, the inflation-adjusted mean cost for the next year would have been $1,324.57 instead of $1,265.11. Depending on the local situation, it may also be appropriate to modify future cost expectations for other actuarial factors such as changes in benefit structure of costsharing provisions. Please note that the above discussion was meant to offer general instructional guidance on the rescaling of relative values and inflation adjustment. Given that no two analytic or actuarial applications are exactly alike, and given the potentially major impact such a process may have on the management or financial applications within your organization, it is essential that you seek and follow advice from experienced statistical or actuarial specialists before finalizing the general processes described above. 50 Table 2: Relative Concurrent PMPY Weights ACG 0100 0200 0300 0400 0500 0600 0700 0800 0900 1000 1100 1200 1300 1400 1500 1600 1710 1711 1712 1720 1721 1722 1730 1731 1732 1740 1741 1742 1750 1751 1752 1760 1761 1762 1770 1771 1772 1800 1900 2000 2100 2200 ACG Label Acute Minor, Age 1 Acute Minor, Age 2 to 5 Acute Minor, Age > 5 Acute Major Likely to Recur, w/o Allergies Likely to Recur, with Allergies Asthma Chronic Medical, Unstable Chronic Medical, Stable Chronic Specialty Eye/Dental Chronic Specialty, Unstable Psychosocial, w/o Psych Unstable Psychosocial, with Psych Unstable, w/o Psych Stable Psychosocial, with Psych Unstable, w/ Psych Stable Preventive/Administrative Pregnancy: 0-1 ADGs Pregnancy: 0-1 ADGs, delivered Pregnancy: 0-1 ADGs, not delivered Pregnancy: 2-3 ADGs, no Major ADGs Pregnancy: 2-3 ADGs, no Major ADGs, delivered Pregnancy: 2-3 ADGs, no Major ADGs, not delivered Pregnancy: 2-3 ADGs, 1+ Major ADGs Pregnancy: 2-3 ADGs, 1+ Major ADGs, delivered Pregnancy: 2-3 ADGs, 1+ Major ADGs, not delivered Pregnancy: 4-5 ADGs, no Major ADGs Pregnancy: 4-5 ADGs, no Major ADGs, delivered Pregnancy: 4-5 ADGs, no Major ADGs, not delivered Pregnancy: 4-5 ADGs, 1+ Major ADGs Pregnancy: 4-5 ADGs, 1+ Major ADGs, delivered Pregnancy: 4-5 ADGs, 1+ Major ADGs, not delivered Pregnancy: 6+ ADGs, no Major ADGs Pregnancy: 6+ ADGs, no Major ADGs, delivered Pregnancy: 6+ ADGs, no Major ADGs, not delivered Pregnancy: 6+ ADGs, 1+ Major ADGs Pregnancy: 6+ ADGs, 1+ Major ADGs, delivered Pregnancy: 6+ ADGs, 1+ Major ADGs, not delivered Acute Minor and Acute Major Acute Minor and Likely to Recur, Age 1 Acute Minor and Likely to Recur, Age 2 to 5 Acute Minor and Likely to Recur, Age > 5, w/o Allergy Acute Minor and Likely to Recur, Age > 5, with Allergy 51 Relative Weight 0.335 0.174 0.182 0.416 0.245 0.300 0.250 1.023 0.334 0.246 0.200 0.341 0.444 1.291 2.490 0.144 3.390 5.461 0.972 3.922 6.058 1.283 5.667 6.722 2.671 4.240 6.575 1.941 5.997 7.637 3.181 4.616 7.144 2.854 7.411 9.037 5.634 0.710 0.665 0.401 0.427 0.541 ACG 2300 2400 2500 2600 2700 2800 2900 3000 3100 3200 3300 3400 3500 3600 3700 3800 3900 4000 4100 4210 4220 4310 4320 4330 4410 4420 4430 4510 4520 4610 4620 4710 4720 4730 4810 4820 4830 4910 4920 4930 4940 5010 5020 5030 ACG Label Acute Minor and Chronic Medical: Stable Acute Minor and Eye/Dental Acute Minor and Psychosocial, w/o Psych Unstable Acute Minor and Psychosocial, with Psych Unstable, w/o Psych Stable Acute Minor and Psychosocial, with Psych Unstable and Psych Stable Acute Minor and Likely to Recur Acute Minor/Acute Major/Likely to Recur, Age 1 Acute Minor/Acute Major/Likely to Recur, Age 2 to 5 Acute Minor/Acute Major/Likely to Recur, Age 6 to 11 Acute Minor/Acute Major/Likely to Recur, Age > 11, w/o Allergy Acute Minor/Acute Major/Likely to Recur, Age > 11, with Allergy Acute Minor/Likely to Recur/Eye & Dental Acute Minor/Likely to Recur/Psychosocial Acute Minor/Acute Major/Likely Recur/Eye & Dental Acute Minor/Acute Major/Likely Recur/Psychosocial 2-3 Other ADG Combinations, Age < 18 2-3 Other ADG Combinations, Males Age 18 to 34 2-3 Other ADG Combinations, Females Age 18 to 34 2-3 Other ADG Combinations, Age > 34 4-5 Other ADG Combinations, Age < 18, no Major ADGs 4-5 Other ADG Combinations, Age < 18, 1+ Major ADGs 4-5 Other ADG Combinations, Age 18 to 44, no Major ADGs 4-5 Other ADG Combinations, Age 18 to 44, 1+ Major ADGs 4-5 Other ADG Combinations, Age 18 to 44, 2+ Major ADGs 4-5 Other ADG Combinations, Age > 44, no Major ADGs 4-5 Other ADG Combinations, Age > 44, 1+ Major ADGs 4-5 Other ADG Combinations, Age > 44, 2+ Major ADGs 6-9 Other ADG Combinations, Age < 6, no Major ADGs 6-9 Other ADG Combinations, Age < 6, 1+ Major ADGs 6-9 Other ADG Combinations, Age 6 to 17, no Major ADGs 6-9 Other ADG Combinations, Age 6 to 17, 1+ Major ADGs 6-9 Other ADG Combinations, Males, Age 18 to 34, no Major ADGs 6-9 Other ADG Combinations, Males, Age 18 to 34, 1+ Major ADGs 6-9 Other ADG Combinations, Males, Age 18 to 34, 2+ Major ADGs 6-9 Other ADG Combinations, Females, Age 18 to 34, no Major ADGs 6-9 Other ADG Combinations, Females, Age 18 to 34, 1+ Major ADGs 6-9 Other ADG Combinations, Females, Age 18 to 34, 2+ Major ADGs 6-9 Other ADG Combinations, Age > 34, 0-1 Major ADGs 6-9 Other ADG Combinations, Age > 34, 2 Major ADGs 6-9 Other ADG Combinations, Age > 34, 3 Major ADGs 6-9 Other ADG Combinations, Age > 34, 4+ Major ADGs 10+ Other ADG Combinations, Age 1 to 17, no Major ADGs 10+ Other ADG Combinations, Age 1 to 17, 1 Major ADGs 10+ Other ADG Combinations, Age 1 to 17, 2 Major ADGs 52 Relative Weight 0.528 0.278 0.582 1.282 2.427 0.912 1.326 0.894 0.835 1.355 1.347 0.582 0.970 2.564 2.164 0.687 1.028 0.851 1.111 0.995 2.137 1.263 2.349 4.892 1.487 2.759 6.433 1.935 4.684 1.818 5.595 1.984 3.880 9.507 2.045 3.456 7.024 3.432 7.231 14.774 27.726 3.872 7.739 27.144 ACG 5040 5050 5060 5070 5100 5110 5200 5310 5311 5312 5320 5321 5322 5330 5331 5332 5340 5341 5342 9900 ACG Label 10+ Other ADG Combinations, Age > 17, 0-1 Major ADGs 10+ Other ADG Combinations, Age > 17, 2 Major ADGs 10+ Other ADG Combinations, Age > 17, 3 Major ADGs 10+ Other ADG Combinations, Age > 17, 4+ Major ADGs No Diagnosis or Only Unclassified Diagnosis & Non-Users (1 input file) No Diagnosis or Only Unclassified Diagnosis (2 input files) Non-Users (2 input files) Infants: 0-5 ADGs, no Major ADGs Infants: 0-5 ADGs, no Major ADGs, low birth weight Infants: 0-5 ADGs, no Major ADGs, normal birth weight Infants: 0-5 ADGs, 1+ Major ADGs Infants: 0-5 ADGs, 1+ Major ADGs, low birth weight Infants: 0-5 ADGs, 1+ Major ADGs, normal birth weight Infants: 6+ ADGs, no Major ADGs Infants: 6+ ADGs, no Major ADGs, low birth weight Infants: 6+ ADGs, no Major ADGs, normal birth weight Infants: 6+ ADGs, 1+ Major ADGs Infants: 6+ ADGs, 1+ Major ADGs, low birth weight Infants: 6+ ADGs, 1+ Major ADGs, normal birth weight Invalid Age or Date of Birth 53 Relative Weight 5.583 8.915 15.633 35.800 0.017 0.144 0.000 1.197 7.987 1.053 5.596 23.145 2.658 2.593 8.387 2.206 17.332 42.535 8.729 0.000 Section 5 Selecting the Right Tool from the Expanding ACG “Tool Box” The preceding sections of this Release Document and the many sections of the comprehensive Version 5.0 Documentation and Application Manual offer significant levels of detail on each of the alternative applications of the various ACG measures. But even with this large mount of material to help guide your way, we recognize that a simple overview is needed to suggest which tool you should select from the Version 6.0 ACG “tool box” for each application within your organization. Targeted at both new and old users alike, this section offers a quick overview of the myriad ACG applications and suggests how the various components of the ACG tool box might be combined to maximize their usefulness to you. In a succinct fashion, this section also attempts to summarize some material that is presented elsewhere in our documentation. Where possible, linkages to more detailed discussion are offered to readers. a. “One Size Does Not Fit All” For over a decade the Johns Hopkins ACG risk-adjustment/case-mix methodology has been applied by many hundreds of users to meet an extremely diverse range of health care management and organizational needs. The ACG System represents a suite of tools that have been used to support basic and complex applications in finance, administration, care delivery, and evaluative research. These applications have been both real-time (concurrent) and forwardlooking (prospective). They may involve simple spreadsheet calculations or complex multivariable statistical models. No other risk adjustment method has been used for so many purposes in so many places, while at the same time showing such high levels of quantitative and qualitative success. The flexibility offered by our tool box means that we recognize that “one size does not fit all.” This also means that a bit of custom tailoring may be needed to get the best fit within your organization. The current ACG release represents a major expansion of the array of tools available within the Johns Hopkins ACG technology. As described earlier in this document, the acgPM model included in this software release produces two new “predictive” measures: a probability score indicating the likelihood that an individual will be a member of your very “high risk” cohort next year, and a Predicted Resource Index (PRI) that reflects the likely amounts of 55 resource use by persons next year relative to the other individuals in your population. In addition to these two brand new prospective measures of risk, this release also provides you with the option of using software-supplied concurrent weights for ACG cells (using the same reference population we used to develop acgPM) and provides a fixed set of ACG-based RUB categories. With more power and functionality come more options for users to navigate. The purpose of this section is to provide some help in making decisions about using the ACG System to support your individual requirements. b. Describing a Population’s Health The ACG System is designed as a tool for understanding and explaining population health. The System’s various diagnosis-based risk assessment markers provide a useful means for comparing the morbidity of different subpopulation of interest to you. Simple descriptive analyses like those shown in the following sample tables compare the distribution of morbidity across selected populations groupings. These are offered as models for how you may wish to apply our system to describe the morbidity characteristics of those cared for by your organization. Table 1: Comparison of ADG Distribution Across Two Enrollee Groups ADG 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 Description Time Limited: Minor Time Limited: Minor -Primary Infections Time Limited: Major Time Limited: Major-Primary Infections Allergies Asthma Likely to Recur: Discrete Likely to Recur: Discrete-Infections Likely to Recur: Progressive Chronic Medical: Stable Chronic Medical: UnStable Chronic Specialty: Stable-Ortho Chronic Specialty: Stable-ENT Chronic Specialty: Stable-Eye No Longer in Use Chronic Specialty: UnStable-Ortho 56 Total 14.7% 32.2% 5.5% 6.1% 3.6% 4.4% 8.6% 20.7% 2.0% 12.9% 8.6% 0.9% 0.7% 2.6% 0.0% 0.8% Group 1 14.8% 33.2% 4.0% 5.1% 3.6% 4.2% 6.6% 22.0% 0.8% 7.4% 4.0% 0.5% 0.6% 2.0% 0.0% 0.4% Group 2 14.4% 27.4% 12.3% 10.6% 3.3% 5.0% 17.2% 14.9% 7.7% 37.1% 28.8% 2.8% 1.4% 5.3% 0.0% 2.4% ADG 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 Description continued Chronic Specialty: UnStable-ENT Chronic Specialty: UnStable-Eye No Longer in Use Dermatologic Injuries/Adverse Effects: Minor Injuries/Adverse Effects: Major Psychosocial: Time Limited, Minor Psychosoc:Recur or Persist: Stable Psychosoc:Recur or Persist: UnStable Signs/Symptoms: Minor Signs/Symptoms: Uncertain Signs/Symptoms: Major Discretionary See and Reassure Prevention/Administrative Malignancy Pregnancy Dental Total Group 1 Group 2 0.0% 1.6% 0.0% 4.5% 10.8% 9.3% 3.5% 9.8% 5.8% 16.9% 17.5% 14.8% 5.8% 1.8% 43.5% 1.0% 2.2% 1.4% 0.0% 0.8% 0.0% 4.4% 10.2% 8.1% 3.0% 7.4% 2.5% 15.3% 14.1% 11.6% 4.8% 1.3% 46.7% 0.3% 2.6% 1.4% 0.1% 5.2% 0.0% 5.0% 13.7% 14.3% 5.5% 20.3% 20.1% 24.4% 32.3% 28.9% 10.4% 3.8% 29.5% 4.0% 0.3% 1.7% Table 1 illustrates how ADGs, the building blocks of the ACG system, can quickly demonstrate differences in types of morbidity categories across sub-groupings within your organization. In this example, the case-mix profile of Group 2 tends to be more complex than that of Group 1, with the prevalence of the chronic medical and psychosocial ADGs being especially high. An advantage of ADGs is they can quickly identify clinically meaningful morbidity trends that may be obscured at the disease-specific or relative morbidity index levels. As discussed in the “Overview of New Features in ACG Release 6.0” section of this document, the ACG software will automatically assign a six-level (Low to High) simplified morbidity category we term RUBs (for Resource Utilization Bands). The six RUBs are formed by combining the ACG mutually exclusive cells that measure overall morbidity burden. Utilizing the Release 6.0 RUB categories, Table 2 demonstrates how a simple RUBbased analysis highlights differences in the distribution of morbidity of the Group 1 and Group 2 exemplary sub-populations. Confirming the impression drawn from Table 1, the Group 2 population clusters in the bands associated with higher overall morbidity burdens. 57 Table 2: Percentage Distribution of Two Sub-groups, by RUB Categories RUB Category 1 - Non-users 2 - Healthy Users 3 - Low Morbidity 4 - Moderate 5 - High 6 - Very High Total Group 1 Group 2 25.8 35.6 22.5 13.9 17.5 11.1 28.3 30.1 25.0 27.6 13.8 33.5 3.7 2.5 7.4 .7 .5 1.5 As discussed earlier in this document, through use of disease-specific EDCs a “standardized morbidity ratio” report is now included as part of the standard ACG print file.3 Based on the “Major” subheadings of Expanded Diagnosis Clusters, this report presents MEDC level disease prevalence of a sub-population of interest after taking into account the age and gender mix of the group relative to the underlying population. Thus, this report will assist users in isolating statistically significant (demographically adjusted) disease category differences within a sub-population of interest. The diagnostic/morbidity distribution reports outlined here should be useful for many clinically oriented applications within your organization. These could include population clinical needs assessments and targeting where disease management or outreach programs might be developed. 3 See “Refinements to the Johns Hopkins Expanded Diagnosis Clusters (EDCs)” in the Version 6.0 Release Notes and Chapter 13, “Dino-Clusters: The Johns Hopkins Expanded Diagnosis Clusters (EDCs)” in the Version 5.0 Documentation and Application Manual for additional details on interpreting this table and how to generate this table on other desired population groups. 58 Table 3. Observed to Expected Standardized Morbidity Ratio (SMR) by MEDC Population: AW Number of persons=167109 Observed Age/Gender Approximate Prevalence Expected 95 percent per 1000 per 1000 confidence interval Major EDC Population Population SMR (low) (high) --------------------------------- ---------- ---------- --------- --------- --------Administrative.................... 269.87 280.93 0.961 0.952 0.969 Allergy........................... 75.56 63.50 1.190 1.169 1.211 Cardiovascular.................... 86.29 79.18 1.090 1.072 1.108 Dental............................ 6.65 7.60 0.876 0.824 0.927 Ears, Nose, Throat................ 172.29 211.01 0.817 0.807 0.826 Endocrine......................... 40.65 31.44 1.293 1.262 1.324 Eye............................... 54.53 121.67 0.448 0.439 0.457 Female Reproductive............... 88.28 81.09 1.089 1.071 1.106 Gastrointestinal/Hepatic.......... 67.47 57.13 1.181 1.159 1.203 General Signs and Symptoms........ 80.15 70.37 1.139 1.120 1.158 General Surgery................... 108.65 100.40 1.082 1.066 1.098 Genetic........................... 0.25 0.24 1.045 0.729 1.360 Genito-urinary.................... 50.53 48.01 1.053 1.030 1.075 Hematologic....................... 11.49 10.53 1.091 1.042 1.139 Infections........................ Malignancies...................... Musculoskeletal................... Neurologic........................ Nutrition......................... Psychosocial...................... Reconstructive.................... Renal............................. Respiratory....................... Rheumatologic..................... Skin.............................. Toxic Effects..................... Unassigned........................ c. 28.20 14.01 164.24 66.96 10.04 51.25 24.36 8.87 126.73 14.72 144.07 4.49 128.37 36.80 11.10 184.12 58.69 10.86 40.68 27.22 5.27 140.04 12.44 149.81 5.51 99.34 0.766 1.263 0.892 1.141 0.924 1.260 0.895 1.684 0.905 1.183 0.962 0.815 1.292 0.744 1.212 0.881 1.120 0.880 1.233 0.867 1.598 0.893 1.136 0.950 0.756 1.275 0.788 1.314 0.903 1.162 0.969 1.287 0.922 1.770 0.917 1.230 0.974 0.873 1.309 Profiling Resource Use One of the most popular uses of the ACG software is to set risk-adjusted resource consumption norms for sub-groups of patients/members within an organization. These norms are compared to actual resource use in order to “profile” provider efficiency and to help suggest where over-use and under-use may be a problem. Profiling applications are very amenable to simple actuarial cell strategies for risk adjustment. Most ACG users apply the ACG mutually exclusive cells for this purpose while others have chosen to combine ACGs and use RUBs for these applications. The simpler RUB method is sometimes selected when the population’s numbers are small or when the need to communicate the inner-workings of the methods to a wide audience of providers is critical. If a user has historical claims data (or other similar data sources), it is generally preferable to calculate “expected” resource use values for each ACG (or RUB) for each resource measure of interest (e.g., total cost, hospital use, specialist referrals, pharmacy) based on actual 59 patterns of practice within your organization. If such data are unavailable or inadequate, then the relative weights supplied as part of this release can be used as a proxy.4 Table 4 presents a summary of the most common profiling statistics:5 1) the actual to group average resource use (unadjusted efficiency ratio); 2) the expected to plan average (the case-mix index or morbidity factor); and 3) the actual to expected average resource use (efficiency ratios). The first is a measure of how the profiling group compares to the “average” population. The second, the morbidity factor provides an indication of how “sick” the profiling population is compared to the “average” population. The last statistic, the observed to expected ratio (“O/E Ratio”) provides an indication of how many health care resources were consumed by this group compared to how many resources they would have consumed had they utilized the “average” resource use of the population based on their case-mix characteristics. All three of these statistics are expressed as relative values with the “average” or normative value centered at 1.0. Scores greater than 1.0 indicate higher than average whereas those less than 1.0 indicate lower than average. Tests of statistical significance can be developed to assess outlier status. Clearly the use of risk adjustment provides a dramatically different basis for assessing the performance of the three profiled sites. Profiles such as those summarized above are a useful tool for evaluating performance and allocating resources within a wide range of ACG users. The most common applications include: • financial exchange between MCO and providers, • assessing provider efficiency, • resource planning, • evaluating access to care, and • detecting fraud, waste, and abuse. In the absence of local resource data that can be used to determine local weights, the concurrent weights available within the ACG System can be used to develop summary measures of case-mix for comparisons between groups. 4 See Chapter 8, “Calibrating ACGs for Intended Use: ACG Weights, Resource Utilization Bands, and Carve-outs,” of the Version 5.0 Documentation and Application Manual and the “Using the Available Relative Value Weights” section of this document for a detailed discussion of relevant methodologic issues related to weight calculation. 5 For further details see Chapter 12, “ACG Risk Adjustment and Provider Profiling,” in the Version 5.0 Documentation and Application Manual. 60 Table 4. Comparison of Observed to Expected Visits and Calculation of Three Profiling Ratios SITE A SITE B SITE C 1) Actual Visits per Person 5.35 6.10 6.90 (Observed) 2) Plan Average 5.50 5.50 5.50 3) Actual to Group Average* 0.97 1.11 1.26 (Unadjusted Efficiency Ratio) 4) Number of Expected Visits** 4.30 6.25 5.54 5) Expected to Plan Average*** .78 1.14 1.01 (Morbidity Factor) 6) Observed to Expected Ratio**** 1.24 0.98 1.25 (Adjusted Efficiency Ratio) * ** *** **** Row 1 divided by Row 2 Expected based on ACG characteristics at each site Row 4 divided by Row 2 Row 1 divided by Row 4 d. Disease Management and Case Management Applications As discussed previously, concurrent ACG / RUB morbidity information can be combined with EDCs to control for morbidity differences across a given disease-specific group of interest (e.g., diabetics enrolled in a disease management program). EDCs will be useful in portraying the disease characteristics of a population of interest. Within disease management programs, if significant differences in expected resource consumption exist across the morbidity sub-classes, this analytic approach should be quite useful in better targeting interventions towards sub-groups at higher risk. Along these lines, two new tables (see Tables 5 and 6 for examples) are now part of the print file that the ACG software produces. Each row of these tables represents persons falling into EDC (or MEDC) disease-specific categories; the columns array these individuals into RUB co-morbidity categories according to their ACG assignment. Table 5 presents the percentage distribution for a series of selected EDCs across the five RUB categories. Table 6 presents the expected relative resource use within each RUB. This table illustrates co-morbidity’s profound influence on resource use within individual disease groups. The ACG-based RUBs do a very good job of explaining variations in resource use within specific diseases. The ACG software 61 automatically generates these reports based on nationally representative weights, but such tables are likely to become even more useful when calibrated to local cost and practice patterns.6 Table 5: Percentage Distribution of Each Co-morbidity Level within an EDC (Samples) RUB-1 RUB-2 RUB-3 RUB-4 RUB-5 EDC Very Low Low Average High Very High --------------------------------- --------- --------- --------- --------- --------ADM01:General medical exam 19.8 32.9 39.9 6.2 1.3 ADM02:Surgical aftercare 4.7 19.3 46.6 18.9 10.4 ADM03:Transplant status 3.8 7.7 32.9 26.6 29.1 ADM04:Complications of mechanical 0.0 10.3 32.4 25.5 31.8 ALL01:Allergic reactions 0.0 36.2 53.6 8.5 1.6 ALL03:Allergic rhinitis 0.0 34.5 56.0 8.2 1.3 ALL04:Asthma, w/o status asthmati 0.0 23.6 63.2 10.7 2.5 ALL05:Asthma, with status asthmat 0.0 20.9 58.0 15.6 5.4 ALL06:Disorders of the immune sys 0.0 6.5 47.6 25.5 20.4 CAR01:Cardiovascular signs and sy 0.0 14.5 64.2 15.2 6.1 CAR03:Ischemic heart disease (exc 0.0 0.5 55.7 27.3 16.6 CAR04:Congenital heart disease 0.0 17.9 45.9 23.9 12.4 CAR05:Congestive heart failure 0.0 0.4 36.6 31.1 31.9 CAR06:Cardiac valve disorders 0.0 7.6 59.1 22.2 11.1 CAR07:Cardiomyopathy 0.0 2.2 43.8 30.1 23.9 CAR08:Heart murmur 12.3 25.8 44.5 11.9 5.4 CAR09:Cardiac arrhythmia 0.0 3.7 58.4 24.5 13.3 CAR10:Generalized atherosclerosis 0.0 7.0 43.7 25.4 23.9 CAR11:Disorders of lipoid metabol 0.0 17.3 68.0 10.4 4.2 CAR12:Acute myocardial infarction 0.0 0.2 21.3 39.3 39.2 CAR13:Cardiac arrest, shock 0.0 5.4 19.2 31.2 44.2 CAR14:Hypertension, w/o major com 0.0 20.6 64.7 10.2 4.5 CAR15:Hypertension, with major co 0.0 4.1 55.4 24.1 16.3 As discussed elsewhere, EDCs are very useful for many purposes. If users so choose, they can develop their own reports, and the EDCs that define the rows in Tables 5 and 6 could be replaced by episodes of illness categories that an organization may obtain from other sources. ACG-based RUBs are equally effective in explaining variations in resource use within episodes of care. 6 See Chapter 13, “Dino-Clusters: The Johns Hopkins Expanded Diagnosis Clusters (EDCs),” in the Version 5.0 Documentation and Application Guide for detailed instructions on how to create these tables calibrated to your own data. 62 Table 6: Estimated Concurrent Resource Use by RUB by MEDC (Samples) RUB-1 RUB-2 RUB-3 RUB-4 RUB-5 EDC Very Low Low Average High Very High --------------------------------- --------- --------- --------- --------- --------ADM01:General medical exam 0.19 0.54 1.97 7.12 24.76 ADM02:Surgical aftercare 0.20 0.63 2.31 7.94 27.30 ADM03:Transplant status 0.20 0.65 2.39 8.23 29.89 ADM04:Complications of mechanical 0.00 0.69 2.35 7.97 29.84 ALL01:Allergic reactions 0.00 0.54 2.07 7.49 25.41 ALL03:Allergic rhinitis 0.00 0.54 2.13 7.43 25.40 ALL04:Asthma, w/o status asthmati 0.00 0.62 2.03 7.43 26.10 ALL05:Asthma, with status asthmat 0.00 0.62 2.13 7.50 28.23 ALL06:Disorders of the immune sys 0.00 0.74 2.39 7.71 29.63 CAR01:Cardiovascular signs and sy 0.00 0.60 2.43 7.96 26.56 CAR03:Ischemic heart disease (exc 0.00 0.68 2.25 8.12 25.35 CAR04:Congenital heart disease 0.00 0.73 2.20 7.11 25.56 CAR05:Congestive heart failure 0.00 0.81 2.62 8.30 28.83 CAR06:Cardiac valve disorders 0.00 0.56 2.42 7.86 27.10 CAR07:Cardiomyopathy 0.00 0.73 2.37 8.23 28.69 CAR08:Heart murmur 0.21 0.64 2.22 7.20 23.05 CAR09:Cardiac arrhythmia 0.17 0.61 2.37 8.07 25.82 CAR10:Generalized atherosclerosis 0.00 0.46 2.47 8.23 27.06 CAR11:Disorders of lipoid metabol 0.00 0.49 2.29 8.17 25.14 CAR12:Acute myocardial infarction 0.00 0.82 1.85 7.87 26.28 CAR13:Cardiac arrest, shock 0.00 0.62 2.12 7.74 27.84 CAR14:Hypertension, w/o major com 0.00 0.48 2.28 8.16 25.75 CAR15:Hypertension, with major co 0.00 0.62 2.35 8.31 27.40 e. High-risk Case Identification for Case Management The various components of the “acgPM”—the new ACG predictive modeling module— represent a real advance for users wishing to establish or augment care management programs within their organization. Furthermore, existing ACG measures have many applications in this domain as well. There are many ways to adapt the ACG suite of tools in the pursuit of improved patient care. This sub-section provides a summary and overview of some of the recommended approaches that an organization may wish to consider in the care-management and quality improvement (QI) domains. As discussed in some detail earlier in this document, the new acgPM risk measurement tools provide information at the individual patient level to help identify persons who potentially would be well served by special attention from the organization’s care management infrastructure. This “high-risk case identification” process could be used to target a person for interventions such as a referral to a case-manager, special communication with the patient’s physician, structured disease management programs, or educational outreach. As part of the new acgPM module the Release 6.0 software now includes a report that provides a disease-specific (based on selected individual and aggregated EDCs) distribution of 63 risk probability scores and average expected resource use for different risk cohorts. This latter report, shown here as Table 7, will be potentially be useful in helping to frame a strategy for targeting various risk cohorts within disease management programs. Table 7. Number of Cases and acgPM Predicted Relative Resource Use, by Risk Probability Thresholds for Selected Chronic Conditions Number of Cases Disease Category (EDC) Arthritis Asthma Diabetes Hypertension Ischemic Heart Disease Congestive Heart Failure Hyperlipidemia Low Back Pain Depression Chronic Renal Failure COPD Predicted Relative Resource Use Probability Score Category Probability Score Category ≥0.4 ≥0.6 ≥0.8 <0.4 ≥0.4 ≥0.6 ≥0.8 17,679 940 463 172 2.18 6.82 9.31 15.71 27,863 764 386 136 1.43 6.75 9.29 14.85 16,991 1,307 716 345 2.67 7.59 10.62 17.36 50,122 2,064 1,011 457 2.06 7.25 10.27 17.57 9,330 971 514 242 3.27 7.40 10.35 17.33 1,634 460 292 184 5.17 8.81 12.26 19.61 31,240 1,170 529 186 1.97 7.13 9.49 15.46 61,980 1,493 723 279 1.76 6.53 8.77 14.27 10,190 599 298 113 2.09 6.63 9.03 14.30 742 308 253 183 13.11 16.48 19.40 25.21 6,204 545 301 147 2.58 7.71 10.24 16.68 Total The acgPM’s probability score was fine-tuned to identify persons who will likely be the ones in your organization who would most benefit from special attention. To capitalize on this new method, an organization will want to develop periodic reports of members with high acgPM scores who also meet other organizational criteria, such as • enrollment with certain providers, • falling into certain eligibility categories, • residing in certain geographic areas, or • meeting previous patterns of utilization. After these other stratifiers are taken into consideration as appropriate, a “case finding” report should list all in-scope individuals arrayed from highest to lowest based on the overall acgPM high-risk probability score within your organization. In addition to running the report automatically generated by the software, users are encouraged to develop their own “individual risk summary” reports on each potential case over a certain threshold (say the top 1% of individuals). This target group can be winnowed further by 64 case managers on the basis of various sources of information available from the ACG software and elsewhere. These additional data might include primary care provider information, service history, history of prior inclusion in care management programs, and results from any ongoing surveys (such as health-risk appraisals). Please see the “The ACG Predictive Model: Helping to Manage Care for Persons at Risk for High Future Cost” section of this document for a comprehensive discussion of the new acgPM module and its applications. f. Capitation, Actuarial Underwriting, and Rate Setting ACGs have been successful for so long because they do a good job at capturing the complex interplay of co-morbidities that explain the impact of case-mix on resource use. This factor clearly distinguishes ACGs from other risk-adjustment strategies that treat diseases individually, as if they each have a completely independent effect on health. The validity of the ACG view of illness has been borne out through the successful application of this riskadjustment strategy across a range of applications for over a decade. i. Using ACGs as “Actuarial Cells” The ACG System has made it possible to accomplish risk adjustment with fairly simple and straightforward analytic strategies. For example, ACGs can readily be used as actuarial cells, which have long been the primary actuarial method for both capitation rate setting and underwriting. Actuarial cells represent a fixed number of discrete categories into which individuals are placed based on their expected use of resources. ACGs are very well suited for assigning individuals into these types of actuarial cells. There are a number of advantages associated with using an actuarial cell-based approach to risk adjustment for capitation and underwriting: • Simplicity. Once the population has been classified into around 100 ACG “cells,” it is possible to risk-adjust the population by using a spreadsheet. Some users have chosen to simplify this approach even further by collapsing the ACGs into smaller homogeneous groupings, resource utilization bands (RUBs). Even when grouped into RUBs, studies indicate that ACGs retain much of their explanatory power. 65 • Less prone to gaming or manipulation. Particularly in applications involving rate setting, there could be incentives to “game” risk-adjustment strategies to increase payment. Unlike some other disease-specific risk adjusters, aggressive efforts to capture additional diagnostic codes on the part of providers will have a more limited impact on ACG assignments. Where “code creep” associated with general increases in completeness and accuracy of coding exists, the simplicity of the ACG system makes it very easy to identify this trend and to implement appropriate action, such as re-calibration of weights. • Stability. The conceptual elegance and underlying simplicity of ACGs have made the system very stable over long periods. The underlying clinical “truth” captured by ACGs does not change dramatically with each new data set and each new application. • Ease of making local calibrations. It is very easy to recalibrate ACG-based actuarial cells to reflect local differences in patterns of practice, benefit structure, and provider fees. Especially for capitation and rate-setting tasks, we encourage users to calibrate the ACG output to reflect the unique nature of the local cost structure. The same simplicity that makes it possible to risk-adjust using a spreadsheet makes it equally possible to accomplish recalibration using the same types of simple tools. The ultimate testimony to the value of ACGs used as the basis of actuarial cells is the fact that for almost a decade they have been used to facilitate the exchange of many billions of dollars within numerous private and public health plans in both the United States and Canada. ii. ACGs in Multivariate Models Multivariate regression for risk adjustment has been used for many years by some of the more sophisticated users of ACGs. If additional risk descriptors are available beyond diagnosis, age, and sex, this approach has the potential for improved predictive models. The strength of regression-based strategies is the ease with which additional risk factor information can be incorporated and thereby introduce better control for the effects of case-mix. This ease is also a potential drawback since regression may introduce some assumptions and statistical pitfalls that can be troublesome without seasoned analytical support. Their inherent 66 complexity makes them difficult to calibrate to local cost patterns, and regression models are also potentially easier to game because more factors can be manipulated. Finally, while it is possible to introduce a wide range of variables that improve the model’s explanatory power, this explanatory power is often confined to the data set and time period on which the model is based. The model’s results may end up differing significantly from year to year depending on the interrelations of the myriad risk factors that have been included, a phenomenon referred to as “overfitting.” To address some of these analytic challenges, the acgPM provided as part of this release represents a regression-based strategy that can be applied for prospective financial applications. As discussed, one acgPM output, the probability score, has been specifically tailored for case and disease-management applications. The other acgPM output, the predicted resource index (PRI), assigns a relative value that can be readily converted to dollars. This PRI output is most relevant for financial risk-adjustment applications and can be considered a substitute for ACG cells for prospective rate setting or payment. One important caveat is worth noting here. Prior pharmacy cost has been made an optional “risk factor” variable in the new acgPM. Although it is useful for calculating the most accurate predictions for future costs, we do NOT recommend that models using the optional pharmacy cost predictor be applied to capitation rate setting. Instead, we suggest that the acgPM model relying only on ICD input variables be used for such a purpose. We take this position for the same reason we believe that episode groupers that rely on procedure codes (such as CPT) and “Rx-groupers” based on use of specific medications (as defined by NDC codes) should not be used for rate-setting purposes or efficiency profiles. Risk factor variables of this type, which are directly defined by the providers’ clinical practices, are potentially intertwined with patterns of “over use” or “under use.” Risk-adjusted rates based on these factors may, in a circular manner (termed endogoneity by the economists), lead to setting rates that are inappropriate—either too high or too low. Moreover, when risk factors are determined by such drug use (or procedural) delivery patterns, providers who practice “efficiently” could potentially be penalized for their efficiency. This circularity issue is not a major concern when only diagnostic information (not linked to specific types or settings of service) is used as the main source of information on risk factors. 67 iii. To Regress or Not to Regress: That Is the Question One of the key decision points in using risk adjustment for financial applications is whether to use a simple actuarial cell approach or a more complex multivariate model. If you have been applying ACG-based actuarial cells successfully for some time, there may be little incentive to change since ACGs alone remain a highly effective case-mix adjustment tool. "If it ain’t broke, don’t fix it." If you are just starting out in your selection of methods, you will need to balance the stability and ease of use of ACG-based actuarial cells against the potentially enhanced ability to explain variations in resource use by applying regression modeling strategies. If you have access to additional well-validated risk factor data and if you have previous experience using regression models within your organization, then you should consider using regression. In regression strategies, ACGs, ADGs, and EDCs remain valuable as distinct risk factors to be supplemented by additional data. Although EDCs are useful for identifying individuals with specific high impact diseases, it is important to note that they do not account for burden of co-morbidity as do ACGs. Therefore, we do not generally recommend that EDCs be used as the only means of controlling for case-mix in regression analysis. The ultimate choice of risk-adjustment approach depends on the specific application, and it is prudent to compare both actuarial cell and regression approaches over a span of several years before making a final decision. For multivariate models, the R-squared statistic is often used as an indicator of performance. In fact, extreme caution is recommended when evaluating models based on R-squared values. The R-squared statistic is very sensitive to outlier individuals. Aside from considering measures of model fit, such as the R-squared value, you should consider whether the results are reasonably stable over time. It is also advisable to simulate the degree to which each approach results in over- or under-payment to key segments of your population. iv. Concurrent versus Prospective Applications The time frame used for most rate setting and other financial analyses is a “prospective” or predictive one. That is, this year’s diagnostic information is used to determine risk factors and expected resource consumption in some future period. Thus the weights associated with each risk factor are calibrated to that future period. But this is not the only temporal approach that organizations can use for rate setting. Some ACG users have implemented concurrent rating processes for financial exchanges. In such cases, this year’s expected resource use among the 68 benchmark population is attached to each ACG cell as a relative value rather than next year’s resource use. While we do encourage experienced actuaries and financial analysts to learn more about the advantages and challenges of these innovative concurrent approaches, we do not recommend that organizations apply concurrent approaches to payment without first simulating the impact that these methods might have on the rate-setting process. A real-world example of a concurrent approach to rate setting is one being implemented in Minnesota Medicaid where plan-level payments are based on concurrent ACG-adjusted profiles of the plan. Under this scenario, payment to a health plan is the same for each individual enrollee within a particular plan; however, the amount paid is case-mix adjusted by the plan’s overall morbidity burden (relative to an average, across the population, of 1.0). This approach assumes that the morbidity burden of large groups (i.e., any individual health plan) is fairly stable and that the group’s overall morbidity does not change much by the addition/exit of any one individual. For additional discussion on this and related issues related to risk adjustment as applied to financial exchanges, we encourage readers to review our chapter incorporated into Charles Wrightson’s recently published book Financial Strategy for Managed Care Organizations: Rate Setting, Risk Adjustment, and Competitive Advantage (see http://www.ache.org/pubs/wrightson.cfm for ordering details). Our chapter is available online at http://www.acg.jhsph.edu. Readers are also encouraged to review the ACG bibliography at that site for a variety of articles illustrating ACGs used for capitation. g. In Closing As part of our ongoing commitment to furthering the international state-of-the-art of riskadjustment methodology and supporting ACG users worldwide, we will continue to perform evaluation, research, and development. We will look forward to sharing the results of this work with our user-base via white papers, our web site, peer-reviewed articles, and in-person presentations. After you have carefully reviewed the documentation supplied with this software release, we would welcome your inquiries on any topic of relevance to your use of ACGs within your organization. (Contact us at askacg@jhsph.edu.) We thank you for using ACGs and for 69 helping us to work toward meeting the Johns Hopkins University’s ultimate goal of improving the quality, efficiency, and equity of health care across the United States and around the globe. 70 Section 6 Installation and Usage Intended for old and new users alike, this chapter is written for the programmer/analyst who will be using the software. This chapter begins with an overview of the technical enhancements new to Release 6.0 and is required reading for all users of the software. The remainder of the chapter is divided into the following main sections: • installing the software, • using the software, • required components of the input files and how to pass data to the software, and • output files. Readers are referred to the relevant sections of the ACG Version 6.0 Release Notes and the Version 5.0 Documentation and Application Manual for additional details on calculating or using ACG weights, discussions of the built-in reporting features and how to customize these reports, and other relevant criteria for implementing ACG technologies within your organization. a. For Users Already Familiar with the ACG Software Although the functionality of Release 6.0 has been greatly enhanced, these improvements only slightly affect the installation and use of the software. This section highlights the few important changes so that current ACG System users will be able to get up and running quickly. A full set of current installation and usage instructions follows so that new (and current) users will have all the information that they need readily at hand. What is needed to take advantage of ACG System enhancements involves two new “control card keywords” and four “names” that have been added to the OUTREC control card. The control card keywords allow for additional (and optional) data to be passed to the grouper from the input file; the four names accommodate additional (and optional) output fields produced by the software. 71 i. New Control Card Keywords Two new record layout control card keywords permit the input of two new data fields: 1. POP is used for a group membership identifier such as underwriting group or PCP assignment; and 2. PCOST is used for pharmacy cost data. The group identifier, called POP, serves as a stratifier for producing age/sex-adjusted prevalence rates and standard morbidity ratio reports using the Johns Hopkins Expanded Diagnosis Clusters (EDCs) typology.7 The optional pharmacy cost information, called PCOST, is a useful adjunct that improves performance of the acgPM (see description of the HRCI card below). If pharmacy cost information is available, we recommend its inclusion. ii. New OUTREC Features Four new names have been added to the control card that controls the output file. OUTREC additions are as follows: 1. CWT, to output a set of fixed concurrent ACG weights based on our nationally representative database (written to the output file as ##.###). 2. RUB, to output six resource use levels (Resource Utilization Bands, or RUBs for short) expressed as an ordinal number with values between zero and five as follows: 0 = nonusers 1 = healthy users 2 = low morbidity 3 = moderate morbidity 4 = high morbidity 5 = very high morbidity 3. HOS, to output a Boolean indicator (e.g., a value of zero or one) for the presence of conditions likely to lead to a hospitalization. 4. HRCI, to output the four scores for predictive modeling (written to the output file as ###.###) in the following order: 7 Note: Please refer to Section 2 of this Addenda Additions and Refinements to the Expanded Diagnosis Cluster (EDC) Methodology (including new reports) and ICD-9 Coding Updates and Chapter 13, “ ‘Dino-Clusters’: The Johns Hopkins Expanded Diagnosis Clusters (EDCs),” of the Version 5.0 Documentation and Application Manual for technical specifications necessary to customize these tables to your application. 72 a. Total cost predicted resource index – an estimate for Year 2 total expenditures (including pharmacy charges) expressed as a relative weight; b. Pharmacy cost predicted resource index – an estimate for Year 2 predicted pharmacy expenditures also expressed as a relative weight; c. Probability of being in the high total cost cohort – a probability score with values between zero and one, indicating the likelihood that a person will have high cost in the subsequent time period; and d. Probability of being in the high pharmacy cost cohort – a probability score indicating the likelihood that a person will have high pharmacy cost in the subsequent time period. Also note that users may include the POP and PCOST control cards in the OUTREC statement if they are interested in having this information appear in the output (as well as the input) file produced by the software. iii. Processing Speed and Space Requirements Unlike prior versions of the software that allocated memory dynamically for each individual, the expanded reporting features and modeling components of Release 6.0 require more processing time. Processing time depends on a variety of factors including but not limited to CPU speed, disk read-write speed, available memory and disk space, as well as the size of the input files. As a general guideline the software can be expected to take two to three times longer than previous versions. For groups that are fewer than 100,000 the increase in processing speed is negligible, but for very large populations the software may take substantially longer than prior versions to process similarly sized input files. Note that processing time may be reduced if duplicate diagnoses cards are removed from the input data stream. The expanded reports and model-building component of Release 6.0 now also necessitate the use of temporary files. While the ultimate output file(s) produced by the software will be similar in size to those produced by prior versions of the software (with the addition of space needed to accommodate new OUTREC fields), sufficient disk space must be available for the writing of temporary files. At a minimum the software will need 1 MB of available disk space for general overhead. On top of this, an estimated additional 600 bytes per person for member identifier, age, and sex fields plus an additional 51 bytes per each unique ICD per person are 73 required. To simplify things somewhat, as a general guideline Release 6.0 requires temporary disk space approximately five to six times the size of the input file. Because of the modeling component of the software, there is now for the first time a limit to the maximum number of people that can be processed in one run. We estimate the upper limit to be approximately 3.5 million individuals. The limit is imposed not on the maximum number of individuals, but rather on the maximum allowable temporary file size, which has been set at 2 GB in most operating systems. If you have membership in excess of 3.5 million, please contact your software distributor for further guidance on how best to divide your input file into smaller population subgroupings. iv. The Print File The number of fixed reports has increased in this release, and so the size of the software’s print file can be expected to be larger. The size of the print file will be at least partially determined by the number of levels provided in the population stratifier control card (e.g., POP discussed in the preceding paragraphs) because these reports are generated for each individual stratifier. If hundreds of stratifiers are used, the software will generate hundreds of pages of printed reports. Even if hundreds of stratifiers are included, the print file can be easily managed by loading it into text processing software and globally changing the print font to Courier 8. With this simple adjustment, reports should be legible and page breaks should appear in logical places. Extracts of this file can easily be extracted by using the cut and paste feature to separate files as desired. v. Other The input file or files no longer need to be sorted. Consequently, the NOSORT card is not needed (and is no longer provided). The age reference date must be provided on the DOB card and must be of the form CCYYMMDD. Previously this information could be left blank, and the system date would be used, or it could be provided as YYMMDD. The format of the EDC output file has changed, so current users must change their programs to read data from these files. Although the EDCs are still written from columns one through five, the unique member ID does not begin until column 12 so as to allow for future expanded EDC categories. 74 b. Installing the Software The ACG grouper software is supplied on a diskette or CD. Installation involves copying all files from this disk to your hard disk; other installation steps depend on the platform. If you are upgrading from an earlier release and want to maintain the prior release for comparison purposes, then rename the old executable file before installing the new version. This can be done by using the DOS rename command or the UNIX mv command. Consult your system documentation for more information on renaming files. Alternatively, you could create separate directories for each version of the software, although you should be sure to use the appropriate version. The version of the software used at any one time is listed in the heading of the print file output. i. UNIX Platforms The file supplied on the disk is named ACGGROUP. Copy this file to your UNIX partition. You may then need to change the file mode to allow “execute permission.” This is usually done with the chmod command, e.g., chmod +x acggroup. The software can then be invoked by merely entering acggroup controlcardfilename. By pressing the break key combination for your system (e.g., Ctrl-Break or Ctrl-C), the system can be halted. That completes the UNIX installation. ii. PC Platforms The file supplied on the disk is named ACGGROUP.EXE. Copy this file to your hard disk for the PC-DOS installation. 75 c. Using the Software Figure 1. Opening Screen for ACG Version 6.0. After copying the file to the appropriate subdirectory, to access the software (acggroup.exe) simply double click8 on the file listing or icon using Windows Explorer or File Manager. Figure 1 is a screen capture of what should appear. The software prompts for the controlcardfilename. The controlcardfilename specifies the location of a file containing a series of ACG control cards that communicate to the software a) the location of the input and output files and what fields to read from the input file, b) which ACG branching options are to be used, and c) what ACG-based risk assessment variables are to be written to the output file(s). (See Table 1. More detail to follow.) After you type in the full filename and hit return, the software executes and a series of progress bars will appear at the bottom of the screen indicating the percentage of data processed. When 100% of the data is processed, the window automatically closes, and files created by the software will reside in the appropriate directories (as indicated by the control card). If a problem is found with any of the control cards, then an error message is written to the screen and the user must press enter to halt execution of the program (at which time viewing the print file may help users to better ascertain where the problem resides and/or at what point the software stopped executing). 8 Alternatively, type the following from the command line: ACGGROUP CONTROLCARDFILENAME (where CONTROLCARDFILENAME is the filename that contains all of the control cards) 76 Control Card File Table 1: Sample Control Card File ********************************************************************* * CONTROLFILESAMPLE.TXT * FILE DEFINITIONS INPUT1=sample1.txt INPUT2= OUTPUT=sample_acg.txt PRINT=sample_prn.txt EDC=sample_edc.txt * ACG BRANCHING SPECIFICATIONS DELIVERED * INPUT FILE LAYOUT ID=1,11 AGE=12,2 SEX=14,1 PCOST=23,5 POP=28,1 ICD=29,5,3 * OUTPUT FILE LAYOUT OUTREC=ID,ACG,HRCI,CWT The format of the input and output records is controlled through the use of control cards. Table 1 provides an example of a “control card file.” Although, strictly speaking, the order of the control cards does not matter, it may be helpful to think of this file as having four main 77 components. The first part, *FILE DEFINITIONS, specifies the location of the input and output files. The second part, *ACG BRANCHING SPECIFICATIONS, provides specifications on optional branching algorithms (e.g., DELIVERED, LOWWEIGHT discussed in more detail later). The third part, * INPUT FILE LAYOUT, provides additional detail about the positioning of data in the input files. The final component of the control card file, * OUTPUT FILE LAYOUT, specifies the output(s) produced by the software. A few simple rules apply to all control cards. Most have the same general form9: Keyword=parameter1,parameter2,parameter3 Each control card or keyword must start with a valid keyword and must be contained entirely on one line. Control card keywords are not case sensitive, and the order of the control cards in the control file does not affect the program. Comment lines, starting with either an asterisk (*), a forward slash followed by an asterisk (/*), or two forward slashes (//) are ignored. The parameters of the card depend on which keyword is being used, and all three parameters are not always required. The number required depends on the keyword. For example, on the ID control card, only two parameters are allowed: the starting column and the length. On the ICD card, three parameters are allowed: the starting column, the length, and the number of occurrences. On the DELIVERED card, no parameters are required. Most parameters are simply integers defining the starting column and length of an item. Some parameters, such as on the FEMALE card, must be enclosed in quotation marks. Table 2 presents all valid control card keywords followed by a detailed description of each. Control cards may also be used to control certain user-defined options. Specifically, EDC reporting, the splitting of pregnancy into “delivered” and “not delivered” categories, and the optional bifurcation of newborns into “low” and “normal” birth weight categories are all controlled by the appropriate control card(s). 9 OUTREC=field, field, … is one exception. 78 Control Card Keywords Table 2: Control Card Keywords (1) Filenames EDC INPUT1 INPUT2 NONMATCH OUTPUT PRINT (1) (2) Record Layout AGE DOB FEMALE ICD ID ID2 OUTREC SEX (3) Optional Fields DELIVERED DELIVERED2 FIELD LOWWEIGHT LOWWEIGHT2 POP PCOST PREGNANT PREGNANT2 (4) Miscellaneous LRECL1 LRECL2 NOCRLF NOWARN Filenames (1) EDC This card invokes the optional Dino-Cluster algorithm and instructs the system to output a Dino-Cluster file. The format of this card is as follows: EDC=filename where filename is the complete path and filename for the Dino-Cluster output file. The use of this card is optional. In addition to providing a file of individual level EDC assignment, inclusion of this card produces a series of additional descriptive tables in the print file. (2) INPUT1 This file is used to specify the location of the input file for the software as follows: INPUT1= filename where filename is the complete path and filename for the input record. The input data must consist of records that contain a person’s ID, age or date of birth, sex, and ICD-9 code(s) of the patient. The user may also provide additional information about pregnancy, delivery status, birth weight, population grouping variable (e.g., PCP assignment) and pharmacy cost. General considerations of the components, structure, and format of this file are discussed in more detail 79 in the next section of this chapter. Control card keywords are used to indicate the starting and ending columns of the various pieces of data required in the input file. (3) INPUT2 The control card for INPUT2 is functionally identical to INPUT1 and is invoked as follows: INPUT2=filename where filename is the complete path and filename for the second input file. The second input file, while similar to the first, is typically limited to diagnosis information only (but occasionally is used to carry user-defined flags for pregnancy, delivery, and low birth weight status). (4) NONMATCH The NONMATCH card is used to specify the file to which unclassifiable diagnoses are to be written. Analysis of this file, consisting of unique combinations of member ID and diagnosis codes not found in the ICD-9 to ADG mapping, is often useful for evaluating the quality of the input diagnosis and/or effectiveness of the assignment algorithm. The format of this control card is as follows: NONMATCH=filename where filename is the complete path and filename for the nonmatch file. (5) OUTPUT The OUTPUT card is used to specify the file into which ACG assignments (and, at the user’s discretion, ADG and other assignments) are to be written and is of the form: OUTPUT= filename where filename is the full path/directory and name into which this file is to be written. (6) PRINT The general summaries of the run, warnings, and error messages are written to the designated print file. The format of this control card is as follows: PRINT=filename 80 where filename is the complete path and filename. Discussed in more detail in a subsequent section, the print file includes summary statistics and simple statistical reports on the ADG, ACG, and EDC distributions of this population. (2) Record Layout (1) AGE This card is used to specify the position and length of the age on the INPUT file (discussed in more detail later in this document) as follows: AGE=start,length where start and length indicate starting columns and number of columns to read from the input. The age must be right justified or incorrect results may occur. Note that either an AGE or a DOB card can be specified, but not both. If two input files are used, the AGE code must appear on the first file. (2) DOB This card is used as an alternative to the AGE card. It specifies that the date of birth is to be used in the age calculation as follows: DOB=start,format,agedate where start indicates the starting column from the input, and format indicates the format of the date as follows: 1=YYMMDD 2=CCYYMMDD (CCYY=century & year, e.g., 1990) 3=MMDDYY 4=MM/DD/YY 5=MM/DD/CCYY 6=YYDDD (Julian date) 7=YYMM (a day of 01 is assumed) 8=CCYYDDD (Julian date) If the DOB card is used then an agedate, indicating the date from which the age is to be computed, must be provided and the format must be CCYYMMDD. Note: Either an AGE or a DOB card can be specified, but not both. If two input files are used, the DOB code must appear on the first file. 81 (3) FEMALE This card is used to recode the sex for females as follows: FEMALE=“code” The optional code indicates the code on the input to consider female. This card is used to override the default assumption of 2 or F for female. All other codes are considered male. To recode blanks, insert the proper number of blanks between the two quotation marks. There may be more than one FEMALE card to supply additional codes. This code is found on the first file, if two input files are used. (4) ICD This card is used to control the position and length of the ICD-9 codes as follows: ICD=start,length,number where start is the starting column of the input, length is the length of each field, and number is the number of consecutive codes. If number is not specified, then the software assumes there is only one diagnosis code per line. The user can specify more than one ICD card, a useful option if the diagnosis codes are in different positions on the same record. If two files are used, ICD codes should always be on the second file. (5) ID This card is used to specify the position and length of the person ID as follows: ID=start,length where start and length indicate starting columns and number of columns to pick up from the input. Note that the ID fields can exist in multiple columns and do not have to be contiguous on a record. Multiple ID cards would be used to define the position and lengths of the parts of a noncontiguous ID. (6) ID2 This card is used to specify the position and length of the person ID on input file 2 as follows: ID2=start,length 82 where start and length indicate starting columns and number of columns to pick up from the input. Note that the ID does not have to be contiguous on a record. If only one input file is used, then the ID2 card is not needed. If an ID2 card is specified, but no second input file is specified, then a warning message is given. If a second input file is specified but no ID2 card is included, then the ID position in file 2 is assumed to be the same as the ID position in file 1. (7) OUTREC This card is used to control the format of the OUTPUT record as follows: OUTREC=field,field,field,... where the fields are used to specify the order of the output. If no OUTREC control card is used, the default is to write out only the ID and ACG. Any of 14 predefined fields or any user-defined field (see the FIELD control card) may be specified in any order. The predefined field names are: ACG, ADG, AGE, CWT, DEL, DOB, HOS, HRCI, ICD, ID, LOW, POP, PCOST PRE, RUB, and SEX. Except for the ICD-9 codes, the fields will be written out in the order specified. If ICD-9 codes are indicated for output, they will always be written at the end of the output record regardless of where they are specified on the OUTREC card. Please see the separate section subsequent in this document entitled “Output Files” for additional details on what is written to the output files produced by the software. (8) SEX This card controls the position and length of the sex field as follows: SEX=start,length where start and length indicate starting columns and number of columns. Note: Sex codes are always found in the first input file. (3) Optional Fields (9) DELIVERED This card instructs the system to classify patients who are associated with a pregnancy according to whether they delivered during the period of observation. If the DELIVERED card is used, ACGs associated with pregnancy (those beginning with ‘17’) will end with ‘1’ (delivered) or ‘2’ (no delivery). The format is: DELIVERED 83 If the DELIVERED card is not used, the software will not assign an ACG that specifies delivery status, and the ACGs associated with pregnancy (those beginning with ‘17’) will end in ‘0’. The user may also use this control card to specify the location of a user-supplied flag on the first input file (INPUT1) indicating that the woman has delivered a baby during the period of observation. The format is: DELIVERED=start,"code" where start is the starting column number on the input record of the data used to indicate a delivery, and "code" is the value of the data that indicates a delivery. For example, DELIVERED=106,"1" indicates that if column 106 in the input data contains “1”, the patient delivered a baby. There is no limit to the number of DELIVERED cards that can be used. Note: If the user-supplied flags indicate a woman delivered, but there is no other indication that she was pregnant, then a warning message is printed, and the woman is automatically considered to have been pregnant. (10) DELIVERED2 This card is identical to the DELIVERED control card, except that it is used to identify values in data file 2, when two input data files are used. (11) FIELD This card specifies a user-defined field as follows: FIELD=field name,start,length where field name is a user-defined name for this field. The user-defined name cannot be one of the predefined names (see OUTREC card description). Start and length indicate the starting column and number of columns for the field. A field name can be defined only once. Userdefined fields are picked up from the INPUT1 file only. Field names may then be used on the OUTREC card to write those fields to the output record. Examples of using the field card include picking up and carrying through to the output record a population stratifier variable or some resource measure, such as total charges, thereby enabling further analysis of the output file without having to re-merge these data. Note a few restrictions on the field name: 1) it must be 10 84 characters or fewer, 2) it must start with an alphabetic letter, and 3) it can contain only letters and numbers. (12) LOWWEIGHT This control card instructs the system to classify infant patients according to whether they had low birth weight, i.e., less than 2,500 grams. To do this, the user must specify the location of a user-supplied flag on the first input data file that indicates that a newborn had a low birth weight. This flag should only be used for patients who are infants (1 year or younger) during the observation period. The format is: LOWWEIGHT=start,"code" where start is the starting column number on the input record and "code” is the value of the data used to indicate low birth weight. For example, LOWWEIGHT=107,"1" indicates that if column 107 is “1”, the infant should be considered to have had low birth weight. There is no limit to the number of possible LOWWEIGHT cards. Please note that the use of the LOWWEIGHT card is optional. If the LOWWEIGHT card is not used, the software will not assign an ACG that specifies birth weight status. (13) LOWWEIGHT2 This control card is identical to the LOWWEIGHT control card, except that it is used to identify the low birth weight flags on the second input file, when two input data files are used. (14) POP This card is used to specify the position and length of the population stratifier field as follows: POP=start,length where start and length indicate starting columns and length. This field is treated as a character field and may contain any data. (15) PCOST This card is used to specify the position and length of pharmacy cost field as follows: PCOST=start,length 85 where start and length indicate starting columns and number of columns. The PCOST must be all numeric (leading blanks are allowed). It is assumed to be a whole dollar amount (no cents). If it does not meet these conditions, it is set to zero and a WARNING09 will appear in the warning message section of the print file. (16) PREGNANT This control card specifies the location of a flag on the first input file indicating that a woman is pregnant during the period of observation. This flag would be necessary only if comprehensive pregnancy diagnosis data were not available during the period of analysis. For example, some health plans using a global fee for all perinatal services may not have pregnancy diagnoses in their claims data until after delivery has occurred. The format is: PREGNANT=start,"code" where start represents the starting column number on the input record of the data used to indicate a pregnancy and "code” is the value of the data that indicates pregnancy. For example, PREGNANT=105,"1" specifies that if column 105 is “1”, the woman should be considered pregnant. Any other entry indicates that the woman is not pregnant. There is no limit to the number of PREGNANT= cards that can be used at one time. If this card is not used, and no PREGNANT2= card is used (see below), then the software will, by default, use the ICD-9 codes alone to classify patients according to pregnancy status. (17) PREGNANT2 This control card is identical to the PREGNANT= control card, except that it is used to identify the pregnancy values from data file 2, when two input data files are used. (4) Miscellaneous (18) LRECL1 This card is used to specify the record length for input file 1 in the case of fixed-length input records. It is needed only if the input is a fixed length with no end-of-record mark— normally a carriage return and line feed—at the end of each record. It is useful for inputting data directly from database files, which usually store data as fixed length records, or after a header with no end-of-record mark. The format of this card is: 86 LRECL1=length,skip where length is the length of each record, and skip is the number of bytes to skip at the start of the file. At the end of the file, if a complete record cannot be read, then the trailing bytes are ignored. (19) LRECL2 This card is used to specify the record length for input file 2 in the case of fixed-length input records. Its format is identical to that of the LRECL1 card described above. (20) NOCRLF This card is used to specify that output records be written without an end-of-record mark. The format for this card is: NOCRLF (21) NOWARN This card is used to adjust the warning threshold. Normally, the software will abort execution if warnings are produced for more than 20 consecutive people in the first half of the input file. If a NOWARN card is included in the control card file, then although warnings will still be generated, execution will not abort if this threshold is reached. Its format is: NOWARN d. Required Components of the Input File The following are general considerations: • The software accepts only flat ASCII (or .txt) files. • A record may contain more than one diagnosis code. Blank diagnosis codes are simply ignored. • If only one input file is specified, then it is assumed to contain the ID, age or DOB, sex, and ICD-9 codes. This file may contain multiple records per ID. The age and sex are picked up from the first record for a particular ID. When two input files are specified, the first must contain the ID, age or DOB, and sex, and the second must contain the ICD-9 codes and an ID. If two input files are used, then the first should 87 Chapter 9 contain only one record per unique ID, whereas the second can contain multiple records per ID. • The system can use either the age or the date of birth. If the date of birth is supplied, then a date (the AGEDATE) from which to compute the age MUST be supplied on the DOB control card. • The age/DOB and sex are extracted from the first record for each individual in the data set. If a person has more than one record, the age/DOB and sex on subsequent records are ignored. Preliminary validation of age, or the month and day of a date of birth code, should be performed. The software will stop execution if more than 20 consecutive people are identified as having no demographic information or being "older" than 107 years of age in the first half of the input data file. • Special sex codes can be indicated on a control card. i. Augmenting Diagnosis Data Certain aspects of the ACG sorting algorithm are optional and are intended to help the user make a better assessment of the case-mix patterns of the study population. These options are initiated by user-supplied flags for pregnancy, delivery, and/or low birth weight, which serve to augment the diagnosis information typically found in claims or encounter data. Please note that the use of user-supplied data for classifying pregnant women and infants is optional. The discussion here complements that outlined in the Version 5.0 Documentation and Application Manual, Chapter 7, “Basic Data Requirements for ACG Categorization and Analysis,” and discusses the technical ‘how to’ of this process. ii. Pregnancy and Optional User-supplied Information on Pregnancy Status By default, the ACG software searches for a defined set of ICD-9 codes to determine pregnancy status. The diagnosis codes used to indicate a pregnancy include: 640xx-677xx, V22x, V23x, V24x, V27x, and V28x. Individuals with a diagnosis in this range, and who are not otherwise excluded on the basis of age or sex, are assigned an ACG beginning with ‘17.’ If an individual’s diagnoses indicate pregnancy but she is younger than 10 years or older than 55, a warning is issued that the patient is of a suspicious age to be pregnant. Similarly, if an individual’s diagnoses indicate pregnancy but that person is coded as male, a warning is issued of suspicious sex to be pregnant. Those who are coded as male and those who are younger than 5 88 years or older than 60 (regardless of sex) are assumed to have received a pregnancy diagnosis in error and will not be assigned an ACG beginning with ’17.’ Alternatively, the user may decide that available ICD-9 code data are insufficient indicators of pregnancy status. That is, in some cases patients may actually be pregnant when no ICD-9 code is present. User-supplied ‘flags’ can be defined by using control cards (designated PREGNANT or PREGNANT2 and discussed later in this chapter) that serve to augment the ICD-9 diagnosis data. If a user-supplied ‘flag’ indicates pregnancy on the input file, the ACG software will classify such a patient as pregnant regardless of any other indication of pregnancy (including typical exclusions due to inappropriate age and sex). Warnings of suspicious age and/or sex may be issued but the user-defined information will be assumed to be correct. If the ICD-9 data indicate pregnancy when a user-supplied flag does not, the individual will also be assumed to be pregnant as long as she meets the default criteria for age and sex (i.e., female between the ages of 5 and 55). In other words, a user-supplied indication of pregnancy serves as a supplement to the diagnostic data, rather than as a strict replacement. iii. Delivery Status and Optional User-supplied Information on Delivery Status Because of the significant increase in resources used in association with delivery, the user may want to specify that the ACG system categorize pregnant women as either having delivered or not having delivered during the period of observation. Unless otherwise instructed by the user, the ACG system will not automatically attempt to classify pregnant women by delivery status. However, two control cards, DELIVERED and DELIVERED2, can be used to instruct the software to search for either ICD-9 diagnosis codes or a user-supplied flag indicating delivery status. As with the classification of pregnancy status, the user-supplied data serves as a supplement to ICD-9 coding indicating delivery. The ICD-9 codes that the software uses to subdivide these ACG categories include: 664.0, 664.01, 664.11, 664.21, 664.31, 650, 654.21, 656.31, 658.11, 658.21, 658.31, 661.01, 661.11, 661.21, 661.31, 663.11, 663.31, 669.5, 669.7, 669.70, V27* (where * = 0-9). iv. User-supplied Information on Birth Weight Status (Optional) When adequate information is available, the user may also want to specify that the ACG software categorize infants as having either low or normal birth weight, in order to enhance the case-mix adjustment process. Unless otherwise instructed by the user, the ACG system will not 89 automatically attempt to classify infants by birth weight status. However, either one of two control cards, LOWWEIGHT and LOWWEIGHT2, can be used to instruct the software to search for a user-supplied flag indicating birth weight status. Unlike the DELIVERED control card discussed above, the software will not classify patients as low or normal birth weight on the basis of ICD-9 codes. v. ICD-9 Codes and Decimal Points The recoding and handling of explicit or implicit decimal points is automatic and cannot be modified by the user. If no decimal point is detected in the ICD-9 code, then the software assumes that a) the decimal point is implied after the third character, b) the first three characters of the diagnosis code are right justified, and c) the fourth and fifth characters are left justified. For example, "4011 " is assumed to be 401.1, "0112 " is assumed to be 011.2, and "112 " is assumed to be 112. If the input ICD-9 code does contain a decimal point, then the software will take up to three characters to the left of the decimal point and right justify them with leading zeros. It will then take up to two characters to the right of the decimal point and left justify them. For example, “401.1" will be recoded to 4011, “11.2" will be recoded as 0112, and “112.” will be recoded as 112. e. Output Files There are potentially four output files produced by the software, including 1) a print file containing summary statistics of the run; 2) an output file containing (at a minimum) individual level ACG assignment; 3) an optional Expanded Diagnosis Clusters output file containing each unique combination of member IDs and EDC assignment; and 4) a nonmatched file containing unique combinations of member IDs and diagnosis codes not identified by the software. i. Print File The print file of the software provides the following: · A copy of the control cards used for that run. · A listing of the input and output files defined for that run. · Selected summaries of input and output data including: -- the number of input records on the first input file; -- the number of input records on the second input file; -- the number of output records (this is equivalent to the number of persons 90 appearing in either file one or file two); -- the sum of unique diagnosis codes across all input records; -- the sum of unique diagnosis codes across member IDs; -- the sum of unique non-grouped diagnosis codes across member IDs; -- non-grouped diagnosis code percentage; and, -- number of people with non-grouped diagnosis codes. · Frequency and percentage distributions of ACGs and ADGs. · Selected summary statistics of the distribution of ADGs including: -- the number and percent distribution of people with numbers of ADGs ranging from zero to 10 or more per person; -- the number and percent distribution of people with numbers of ACGs ranging from 1 to 4 or more per person; -- the average number of ADGs per person; -- the average number of major ADGs per person; -- the average number of ADGs for those who have an ADG; -- the average number of major ADGs; -- the average number of ADGs for those with an ADG; -- the average number of major ADGs for those with an ADG; -- the average number of ADGs for those with a major ADG; and -- the average number of major ADGs for those with a major ADG. · Selected summary statistics and distribution of unique diagnoses including: -- the average number of unique diagnosis codes per person; -- the average number of unique diagnosis codes per person for those with diagnoses; and -- the number and percent distribution of people with unique diagnosis codes ranging from zero to 10 or more per person; · Age/Sex Distribution. · Frequency distribution of EDCs and MEDCs and prevalence per 1,000 persons. · Average numbers of EDCs per person overall and for those with EDCs. · Percentage distribution of EDC and MEDC in 5 resource utilization bands (RUBs)10. · Estimated concurrent resource use by EDC and MEDC in 5 RUBs. · Observed and age/sex-adjusted prevalence, standardized morbidity ratios (SMRs), and SMR confidence intervals by MEDC. · Frequency and percent distribution of acgPM probability scores. · 10 Number of cases and associated predicted acgPM relative resource use by Note: the non-user RUB is excluded. 91 alternative acgPM risk probability thresholds for selected chronic conditions. · Warning Messages -Warnings associated with each individual who generates a warning are listed on one line per person at the end of the print file. The warning lines include the ID, ACG assignment, age, sex, date of birth (if entered as input), and a list of warnings numbers. The warning numbers can be compared to the text for each warning printed above the individual-level warning data. ii. Output File The output record produced by ACGGROUP is controlled through the OUTREC control card (discussed previously). The fields will be written out only if specified, and in the order specified. The only exception to this rule of order is that ICD-9 codes will be written at the end of the record. The field lengths are as follows: Name Field ACG ACG code Length 4 ADG ADG vector 34 one-character fields for ADG 1–34 (where a 1=the person had this ADG; 0=otherwise) (Please note: Because they are no longer in use, the values for ADG 15 and ADG 19 will always be 0.) AGE Age 3 (right justified, leading zeros) CWT Concurrent weight Based on a nationally representative database. Written to the output file as ##.###. DEL Delivery status 1=person delivered; 2=person did not deliver; 9=optional branching turned off DOB Date of birth 8 in CCYYMMDD format if possible ICD ICD-9 codes 6 characters each (where the first 5 are the ICD-9 code, and a mismatch flag is in the sixth position [1=no ADG code and blank=successfully matched]) ID ID code Same as designated for input HRCI acgPM scores All written to the output file as ###.### in the following order: 1) Total cost predicted resource index – an estimate for Year 2 total expenditures (including pharmacy charges) expressed as a relative weight; 92 2) Pharmacy cost predicted resource index – an estimate for Year 2 predicted pharmacy expenditures also expressed as a relative weight; 3) Probability of being in the high total cost cohort – a probability score with values between zero and one indicating the likelihood that a person will have high cost in the subsequent time period; and 4) Probability of being in the high pharmacy cost cohort – a probability score indicating the likelihood that a person will have high pharmacy cost in the subsequent time period. HOS Hospital Dominant A Boolean indicator (e.g., a value of zero or one) for the presence of conditions likely to lead to a hospitalization. LOW Low birth weight 1=low birth weight; 2=normal birth weight; 9=optional branching turned off PRE 1=person is pregnant; 2=person is not pregnant; Pregnancy status RUB Resource utilization 0 = nonusers band 1 = healthy users 2 = low morbidity 3 = moderate morbidity 4 = high morbidity 5 = very high morbidity SEX Sex code 1 (F=female, M=male) User-defined fields specified on the FIELD card can also be specified for output. The length of user-defined fields is the same as specified by the user on the FIELD cards. If no OUTREC card is included, then the software automatically writes the unique member ID and ACG to the output file. Because the software is not limited to a maximum number of unique ICD-9 codes per person, the number of codes on the output will depend on the number of unique ICD-9 codes for any particular patient. Only unique codes are written to the output. Even if codes are duplicated on the input, only one occurrence of each code is written to the output in the order read. If ICD-9 codes are indicated for output, they will always be written at the end of the output record regardless of where they are specified on the OUTREC card. There is one output record produced for each unique ID. 93 iii. Differentiating Nonusers from Those with Only One Input File If only one input file is used to enter both demographic and diagnostic data, all patients without associated diagnoses or without groupable diagnoses are assigned to ACG 5100. To more cleanly separate nonusers from those who used services but had no classifiable diagnoses, it is recommended that individuals classified into ACG 5100 be subdivided into two groups according to the following criteria. Nonusers, defined as individuals with no claims or encounters, should be reassigned to ACG 5200. This will leave only those individuals in ACG 5100 (which can be renamed 5110) who, although they are users of services, have no diagnosis and/or only unclassified diagnoses. iv. The EDC File The Dino-Cluster output file is optional and will be produced by the software only if the EDC control card is present. The format of this file is as follows: Columns 1-5 6-11 12-n v. Field EDC code space Person ID where n depends on the length of the ID n=11+length of ID Mismatched ICD-9 List All input ICD-9 codes without a corresponding ADG code will be written to an output file called the mismatched ICD-9 file. Because all currently defined ICD-9-CM codes are now included in the ICD to ADG mapping, this mismatch file will typically be limited to: 1) ‘E’ codes that, because they typically indicate the cause of an injury rather than an underlying morbidity, are excluded from the mapping; 2) local coding that is not otherwise included; and 3) genuine errors in coding. Mismatched codes are written out one time for each person who has that code. In this way, the file can be used to get a listing of codes and/or a listing of people who have mismatched codes. It can also be used to count the number of patients with each mismatched code. The format of this file is as follows: Columns 1-5 6-n Field ICD-9 code Person ID where n depends on the length of the ID n=5+length of ID 94 This file should be analyzed carefully. Briefly, using this file to create a frequency distribution of non-grouped ICD-9 codes can help identify diagnosis codes that are not in standard format. Historically, the five most frequently occurring codes will account for more than 50% of all codes not identified by the software. How the codes are justified and/or padded and whether decimal places are explicit or implied are the two leading causes of problems pertaining to mismatched codes. For a more theoretical discussion of ICD-9 coding considerations, see Chapter 7, “Basic Data Requirements for ACG Categorization and Analysis,” of the Version 5.0 Documentation and Application Manual. The software will assign ADGs to "legal" ICD-9-CM and ICD-9 (non-CM) diagnostic codes. In certain circumstances, ADGs will also be assigned to "illegal" codes, where the intent of the codes was clear (for example, a three-digit code that is unambiguous, but where only a four- or five-digit code is considered valid according to official ICD-9 publication vendors). vi. Error Messages Error messages generated by ACGGROUP are either written to the print file or displayed on the screen. Errors are basically of two types: those that involve the control cards and those that involve the data. Each message is numbered. The following sections describe the error messages in order by message number for each of the two types of errors/warnings. Most messages are selfexplanatory and can be resolved by checking the documentation for the specific control card in error. Further clarification is supplied below, as appropriate. vii. Control Card Errors and Warnings The control cards are written to the print file in a numbered list. Control card error messages will, many times, contain a number that refers to the specific control card in that list. While many error messages are generic to multiple control cards, by using the control card number and referring to the list of control cards in the print file, you can easily identify the specific control card in error. For example, given the following control cards: id=x,11 age=12,3 sex=15,1 icd=21,6 The print file would list the control cards as follows: 1: id=x,11 95 2: age=12,3 3: sex=15,1 4: icd=21,6 The following error message would also be printed: ERROR02: Parameter 1 is missing or non-numeric on control card: 1 This message indicates that on control card #1, which is the ID card, the first parameter, which is an “x,” is non-numeric. It should indicate the starting column of the patient ID. The following is a complete list of the control card error messages 1. ERROR01: Two control cards were found and only one is allowed: # Certain control cards are allowed to be used only once per run. The software found more than one of these cards. The number given in the error message points to the control card in error. 2. ERROR02: Parameter 1 is missing or non-numeric on control card: # The control card referenced has an invalid first parameter, which is usually the starting column number. 3. ERROR03: Parameter 1 was not specified on control card: # 4. ERROR04: Parameter 2 is missing or non-numeric on control card: # The control card referenced has an invalid second parameter, which is usually the length. 5. ERROR05: Parameter 2 was not specified or is invalid on control card: # 6. ERROR06: Value must be enclosed in quotes on control card: # 7. ERROR07: Could not obtain memory to hold control cards. Your system does not have sufficient free RAM to read in all of the control cards. Eliminating other programs that are running at the same time as ACGGROUP or adding more system memory will clear up this problem. 8. ERROR08: Not enough memory to continue program: Your system does not have sufficient free RAM. Eliminating other programs that are running at the same time as ACGGROUP or adding more system memory will clear up this problem. 9. ERROR09: Both AGE and DOB control cards were found and only one is allowed: 10. ERROR10: Parameter 3 is non-numeric or not specified on control card: # 11. ERROR11: The date format code specified on the DOB card is invalid: # 12. ERROR12: Age date is non-numeric on control card: # 96 The agedate parameter on the DOB card provides a date upon which to calculate the age. If provided, it must be a numeric field. 13. ERROR13: The month of the age date on the DOB card is invalid: # 14. ERROR14: The day of the age date on the DOB card is invalid: # 15. ERROR15: An undefined field name was specified on the OUTREC card: fieldname The OUTREC card contains a field name that is undefined. It is not one of the predefined names, and it is not a user-defined field name. The field name in question is shown on the card. 16. WARNING16: Field specified at least twice on the OUTREC card: fieldname 17. ERROR17: Unidentifiable keyword on control card: keyword The control file contains a line that cannot be understood by ACGGROUP. Check the proper spelling of the keyword on the control card shown in the message. 18. WARNING18: An ID2 card was used, but no second input file was specified. If no second input file is specified, then an ID2 card is not needed. One was specified that will be ignored. 19. ERROR19: Duplicate, missing, or reserved user field name on FIELD card: # The field card specified by # contains a field name that is already defined, either as a predefined field or on another FIELD card, or it contains no field name. 20. ERROR20: Parameter 3 is not allowed on control card: # The control card specified by # contains something where a third parameter would be specified, but a third parameter is not allowed on this control card. In particular, if this is an ID card, note that previous versions would allow multiple, noncontiguous pieces of the ID to be defined on a single ID card, whereas this version of the software only allows one piece of the ID to be defined per ID card. Multiple ID cards can be used to define other parts of the ID. As an example, in previous versions, the card ID=1,10,20,5 would be acceptable. In this version, this input would generate the error message. The proper coding would be with two ID cards: ID=1,10 and ID=20,5. 97 Appendix A ACG Publication List Adams EK, Bronstein J, Raskind-Hood C. “Adjusted Clinical Groups: Predictive Accuracy for Medicaid Enrollees in Three States.” Health Care Financing Review, 2002, 24(1): 43-61. Adams EK, Bronstein J, Becker E. AMedi-Cal and Managed Care: Risk, Costs, and Regional Variation.@ Public Policy Institute of California, December, 2000. "Adjust Utilization For Case Mix and Make Physicians Responsible For Remaining Variation." February, 1998. Data Strategies & Benchmarks. 25-28. Anderson G, Weller W. “Methods of Reducing the Financial Risk of Physicians Under Capitation.” AMA, Archives of Family Medicine, 1999, Vol 8: 149-155. http://archfami.ama-assn.org/cgi/content/short/8/2/149 AAssessment of Ambulatory Care Groups with Comparison to Existing Ambulatory Case-Mix Classification System.@ Report prepared for the Office of the Assistant Secretary of Defense (Health Affairs) by Systems Research and Applications Corporation and Birch Davis Associates Inc. (CIM Contract Number MDA-903-91-D-0061), Arlington, VA, July, 1994. Blustein J, Hanson K, Shea S. APreventable Hospitalizations and Socioeconomic Status.@ Health Affairs. March/April 1998; 17(2): 177-189. Bono C, Shenkman E, Hope-Wegener D. “The Actual Versus Expected Health Care Use Among Healthy Kids Enrollees.” Institute for Child Health Policy. Tallahassee, Florida, March 2000. http://www.ichp.edu/rquality/materials/ActualvsExpectedHlthCare32000.pdf Briggs LW, Rohrer JE, Ludke RL, Hilsenrath PE, Phillips KT. AGeographic Variation in Primary Care Visits in Iowa.@ Health Services Research. 1995; 30(5): 657-71. Buntin MJB, Newhouse JP. AEmployer Purchasing Coalitions and Medicaid: Experiences with Risk Adjustment.@ The Commonwealth Fund. May, 1998. http://www.cmwf.org/programs/medfutur/buntin286.asp Carlsson L, Borjesson U, Edgren L. “Patient based ‘burden-of-illness’ in Swedish Primary Health Care. Applying the Johns Hopkins ACG Case-mix System in a retrospective study of electronic patient records.” International Journal of Health Planning and Management 2002: 17: 269-282. http://www3.interscience.wiley.com/cgi-bin/fulltext?ID=97518189&PLACEBO=IE.pdf Center for Health Quality, Outcomes, & Economic Research. AHealth Quality Section Update, ACGs: An Ambulatory Care Case-Mix Measure.@ CHQOER Quarterly. ENRM VA Hospital, Bedford, MA. Fall, 1997. A-1 “Characteristics of Maryland Residents Who Obtain Health Insurance from the Small and Large Group Markets.” Report prepared for State of Maryland, Maryland Health Care Commission by The Project HOPE Center for Health Affairs. Bethesda, MD, October 2001. http://www.mhcc.state.md.us/database/extramural/grpmarkfinalrpt.pdf Clark DO, Von Korff M, Saunders K, Baluch WM, Simon GE. AA Chronic Disease Score with Empirically Derived Weights.@ Medical Care. 1995; 33(8): 783-795. Conrad DA, Maynard C, Cheadle A, Ramsey S, Marcus-Smith M, Kirz H, Madden C, Martin D, Perrin E, Wickizer T, Zierier B, Ross A, Noren J, Liang SY. APrimary Care Physician Compensation Method in Medical Groups: Does It Influence The Use and Cost of Health Services For Enrollees in Managed Care Organizations?@ Journal of the American Medical Association. 1998; 279(11): 853-858. http://jama.ama-assn.org/cgi/content/short/279/11/853 Diamond LH. “Profiling: Doing It Right” Medstat.com Healthplan. 2000, May/June 75-79. ADifferences in Case Mix Between CHC Users and Non Users: Washington and Missouri, 1992 Final Report.@ Report prepared for the Bureau of Primary Health Care by MDS Associates, Inc. (HRSA Contract #240-94-0036), Wheaton, MD, June, 1998. Dunn D, Rosenblatt A, Taira D, Latimer E, Bertko J, Stoiber T, Braun P, Busch S. AA Comparative Analysis of Methods of Health Risk Assessment: Final Report.@ Harvard University School of Public Health. 1995. Ellis, RP. “Formal Risk Adjustment by Private Employers.” Boston, MA. June 2001. http://econ.bu.edu/Ellis/Papers/EllisFormalRiskAdjustment.pdf Ettner SJ, Frank RG, McGuire TG, Hermann RC. ARisk Adjustment Alternatives in Paying for Behavioral Health Care Under Medicaid.@ Health Services Research. August 2001; 36(4): 793811. “The Faces of Medicaid” Publication for the Center of Health Care Strategies, Inc., Finance. 71-75. November, 2000. http://www.chcs.org/publications/pdf/cfm/Finance.pdf Fakhraei SH, Kaelin J, Conviser R. “Comorbidity-Based Payment Methodology for Medicaid Enrollees with HIV/AIDS.” Health Care Financing Review. Winter 2001; 23(2): 53-68 Falik M, Needleman J, Wells B, Korb J. “Ambulatory Care Sensitive Hospitalizations and Emergency Visits: Experiences of Medicaid Patients Using Federally Qualified Health Centers.” Medical Care, 2001, 39(6): 551-561. A-2 Fishman PA, Shay DK. ADevelopment and Estimation of a Pediatric Chronic Disease Score Using Automated Pharmacy Data.@ Medical Care. 1999; 37(9): 874-883. FitzHenry F, Shultz EK. AHealth-Risk-Assessment Tools Used to Predict Costs in Defined Populations.@ Journal of Healthcare Information Management. Summer, 2000; 14(2): 31-57. Foldes, S. AManaged Care Holds Down Costs, Doesn=t Hurt Quality.@ January 3, 1998. Minneapolis Star Tribune p. A13. Forrest C, Majeed A, Weiner J, Carroll K, Bindman A. “Referral of Children to Specialists in the United States and the United Kingdom.” Archives of Pediatrics and Adolescent Medicine, March 2003, 157: 279-285. Editorial by Ferris T and Wasserman R, Archives of Pediatrics and Adolescent Medicine, March 2003, 157: 219-220. Forrest CB, Majeed A, Weiner J, Carroll K, Bindman A. “Comparison of Specialty Referral Rates in the United Kingdom and the United States: retrospective cohort analysis.” British Medical Journal. August 2002; 325: 370-371. http://bmj.com/cgi/content/full/325/7360/370 Forrest CB, Reid RJ. APrevalence of Health Problems and Primary Care Physicians= Specialty Referral Decisions.@ J Fam Pract. May, 2001; 50(5): 427-432. http://www.jfampract.com/content/2001/05/jfp_0501_04270.asp Forrest CB, Weiner JP, Fowles J, Vogeli C, Frick KD, Lemke KW, Starfield B. ASelf-Referral in Point-of-Service Health Plans.@ Journal of the American Medical Association. May, 2001; 285(17): 2223-2231. http://jama.ama-assn.org/cgi/content/short/285/17/2223 Forrest CB, Whelan EM. APrimary Care Safety-Net Delivery Sites in the United States: A Comparison of Community Health Centers, Hospital Outpatient Departments, and Physicians= Offices.@ Journal of the American Medical Association. 2000; 284(16): 2077-2083. http://jama.ama-assn.org/cgi/content/short/284/16/2077 Fowler, L., Anderson G. ACapitation Adjustment For Pediatric Populations.@ Pediatrics. 1996; 98(1): 10-17. http://www.pediatrics.org/cgi/content/abstract/98/1/10 Fowles J, Weiner J, Knutson D, Fowler E, Tucker A, Ireland M. ATaking Health Status into Account When Setting Capitation Rates: A Comparison of Risk Adjustment Methods.@ Journal of the American Medical Association. 1996; 276(16): 1316-1321. Franks P, Fiscella K. “Effect of Patient Socioeconomic Status on Physician Profiles for Prevention, Disease Management, and Diagnostic Testing Costs.” Medical Care, 2002, 40(8): 717-724. A-3 Green B, Barlow J, Newman C. AAmbulatory Care Groups and The Profiling of Primary Care Physician Resource Use: Examining the Application of Case-Mix Adjustments.@ Journal of Ambulatory Care Management. 1996; 19(1): 86-89. Harry N. AHopkins health pricing tool a managed care hit.@ July, 1997. Baltimore Business Journal 15(9), p. 20. Holahan J, Rangarajan S, Schirmer M. AMedicaid Managed Care Payment Methods and Capitation Rates: Results of a National Survey.@ Urban Institute, Washington, DC. June, 1999. http://newfederalism.urban.org/html/occa26.html Juncosa S, Bolibar B. AUn Sistema De Clasificacion De Pacientes Para Nuestra Atencion Primaria: Los Ambulatory Care Groups (ACGs)@. Gaceta Sanitaria. 1997; 11(2): 83-94. http://www.uv.es/~docmed/documed/documed/491.html Klabunde C, Warren J, Legler J. “Assessing Comorbidity Using Claims Data.” Medical Care, 2002, 40 (8) Supplement, IV:26-35. Knutson, D. ACase Study: The Minneapolis Buyers Health Care Action Group.@ Inquiry. Summer, 1998; 35: 171-177. Kuhlthau K, Ferris TGG, Beal AC, Gortmaker SL, Perrin JM. AWho Cares for MedicaidEnrolled Children With Chronic Conditions?@ Pediatrics. October 4, 2001, 108(4); 906-912. http://www.pediatrics.org/cgi/content/full/108/4/906 Leibson C, Katusic S, Barbaresi W, Ransom J, O=Brien P. AUse and Costs of Medical Care for Children and Adolescents With and Without Attention-Deficit/Hyperactivity Disorder.@ Journal of the American Medical Association. January, 2001, 285 (1): 60-66. http://jama.ama-assn.org/cgi/content/short/285/1/60 Madden CW, Mackay BP, Skillman SM. AMeasuring Health Status for Risk Adjusting Capitation Payments.@ July 2001, Center for Health Care Strategies, Inc., Princeton, NJ. Madden CW, Mackay B, Skillman S,Ciol M, Diehr P, ARisk Adjusting Capitation: Applications in Employed and Disabled Populations.@ Health Care Management Science. February 2000, 3(2): 101-9. Madden CW, Skillman SM, MacKay B. ARisk Distribution and Risk Assessment Among Enrollees in Washington State=s Medicaid SSI Population.@ 1998, Center for Health Care Strategies, Inc., Princeton, NJ. http://froya.boat.washington.edu/risk-adjust/html/project2.html Madden CW, Stanley MT, Skillman SM, Blough DK, Mackay B, Wilson V, et. al. AImplementing a Model for Risk Distribution Among Competing Health Plans.@ Final Report for the Robert Wood Johnson Foundation. 1998, University of Washington, Seattle, WA. A-4 Majeed A, Bindman AB, Weiner JP. AUse of risk adjustment in setting budgets and measuring performance in primary care I: how it works.@ British Medical Journal. 2001; 323: 604-607. http://www.bmj.com/cgi/reprint/323/7313/604.pdf Majeed A, Bindman AB, Weiner JP. AUse of risk adjustment in setting budgets and measuring performance in primary care II: advantages, disadvantages, and practicalities.@ British Medical Journal. 2001; 323: 607-610. http://bmj.com/cgi/reprint/323/7313/607.pdf Massachusetts Rate Setting Commission. AEvaluation of Casemix Adjustment Methods.@ Final Report and Recommendation for the Massachusetts Division of Medical Assistance. March, 1996. McCracken S. AHealth Information Services Technologies.@ Journal of Ambulatory Care Management. 1996; 19(1): 90-97. AMinimal-Burden Risk Adjusters for the Medicare Risk Progam.@ Report prepared for the Health Care Financing Review by Medical College of VA Associated Physicians and Mathematica Policy Research, Inc. (HCFA Contract No. 17C-90366/3/01), November, 1999. Minnesota Department of Health. ARisk Adjustment and Rate Setting Methods in Public Programs.@ A Report to Legislature prepared by the Health Economics Program for the Minnesota Department of Health. January, 1998. Moore HW, Kaelin J, Johnson S, Mussman M, O’Brien J. “Risk Adjustment for Asthma: Variations by Methodology and Implications for Providers.” Informed Purchasing Series, Center for Health Care Strategies, Inc. Working Paper, December 2001. http://www.chcs.org/publications/pdf/ips/riskadjustforasthma.pdf Orueta J, Lopez-De-Munain J, Baez K, Aiarzaguena J, Aranguren J, Pedrero E. AApplication of the Ambulatory Care Groups in the Primary Care of a European National Health Care System: Does It Work?.@ Medical Care. 1999; 37(3): 238-248. Page L. AMaryland to Test New Medicaid Managed Care Pay Formula.@ American Medical News. December, 1996. Palsbo S, Post R. “Implementing Risk Assessment and Risk Adjustment for People with Disabilities in State Programs: Six Case Studies.” NRH Center for Health and Disability Research, November 2001. http://www.nrhchdr.org/Implementing%20RA-6%20cases.pdf A-5 Parente S, Weiner J, Garnick D, Fowles J, Lawthers A, Palmer R. AProfiling Medicare Beneficiary Resource Use by Primary Care Practices: Implications For a Managed Care Medicare.@ Health Care Financing Review. 1996; Summer: 23-42. Parkerson G, Harrell F, Hammond W, Wang X. “Characteristics of Adult Primary Care Patients as Predictors of Future Health Services Charges.” Medical Care. 2001, 39 (11): 1170-1181. Powe N, Weiner J, Starfield B, Stuart M, Baker A, Steinwachs D. ASystemwide Performance in a Medicaid Program: Profiling The Care of Patients with Chronic Illnesses.@ Medical Care. 1996; 34(8): 798-810. Reid R, Roos N, MacWilliam L, Frohlich N, Black C. “Assessing Population Health Care Need Using a Claims-based ACG Morbidity Measure: A Validation Analysis in the Province of Manitoba.” Health Services Research, 2002, 37(5): 1345-1364. Reid R, Bogdanovic B, Roos NP, Black C, MacWilliam L, Menec V. ADo Some Physician Groups See Sicker Patients than Others? Implications for Primary Care Policy in Manitoba.@ Manitoba Centre for Health Policy and Evaluation, Department of Community Health Services Faculty of Medicine, University of Manitoba. August, 2001. http://www.umanitoba.ca/centres/mchp/reports/pdfs/acg2001.pdf Reid R, MacWilliam L, Roos N, Bogdanovic B, Black C. AMeasuring Morbidity in Populations: Performance of the Johns Hopkins Adjusted Clinical Group (ACG) Case-Mix Adjustment System in Manitoba.@ Manitoba Centre for Health Policy and Evaluation, Department of Community Health Services Faculty of Medicine, University of Manitoba. June, 1999. http://www.umanitoba.ca/centres/mchp/reports/pdfs/acg.pdf Reid R, MacWilliam L, Verhulst L, Roos N, Atkinson M. APerformance of the ACG Case-Mix System in Two Canadian Provinces.@ Medical Care. 2001, 39(1): 86-99. Rosen A, Rakovski C, Loveland S, Anderson J, Berlowitz D. “Profiling Resource Use: Do Different Outcomes Affect Assessments of Provider Efficiency?” American Journal of Managed Care, 2002, 8(12): 1105-1115. Rosen AK, Loveland S, Anderson JJ, Rothendler JA, Hankin CS, Rakovski CC, Moskowitz MA, Berlowitz DR. AEvaluating Diagnosis-Based Case-Mix Measures: How Well Do They Apply to the VA Populations?@ Medical Care. 2001; 39(7): 692-704. Salem-Schatz S, Moore G, Rucker M, Pearson S. AThe Case For Case-Mix Adjustment In Practice Profiling: When Good Apples Look Bad.@ Journal of the American Medical Association. 1994; 272(11): 871-874. Shen Y, Ellis RP. “Cost-Minimizing Risk Adjustment” November 2001. http://econ.bu.edu/ellis/Papers/shen2.pdf A-6 Shen Y, Ellis RP. AHow Profitable is Risk Selection? A Comparison of Four Risk Adjustment Models.@ Health Economics. In Press. April 2001. http://econ.bu.edu/ellis/Papers/Shen1.pdf Shenkman E, Breiner JR. ACharacteristics of Risk Adjustment Systems.@ Working Paper Series, #2. Division of Child Health Services Research and Evaluation, Institute for Child Health Policy, University of Florida. January, 2001. http://www.ichp.edu/rtitlexxi/materials/Crisk.pdf Shenkman E, Pendergast J, Wegener DH, Hartzel T, Naff R, FreedmanS, Bucciarelli R. AChildren=s Health Care Use in the Healthy Kids Program.@ Pediatrics. 1997; 100 (6): 947-953. http://www.pediatrics.org/cgi/content/full/100/6/947 Shields A, Finkelstein J, Comstock C, Weiss K. “Process of Care for Medicaid-Enrolled Children with Asthma.” Medical Care, 2002, 40(4): 303-314. Smith N, Weiner J. AApplying Population-Based Case-Mix Adjustment in Managed Care: The Johns Hopkins Ambulatory Care Group System.@ Managed Care Quarterly. 1994; 2(3): 21-34. Starfield B, Weiner J, Mumford L, Steinwachs D. AAmbulatory Care Groups: A Categorization of Diagnoses For Research and Management.@ Health Services Research. 1991; 26(1): 53-74. Stuart M, Steinwachs D. APatient Mix Differences Among Ambulatory Providers and Their Effects on Utilization and Payments For Maryland Medicaid Users.@ Medical Care. 1993; 31: 1119-1137. Tucker A, Weiner J, Abrams C. Health-Based Risk Adjustment: Application to Premium Development and Profiling. In Wrightson B (edt) Rate Setting, Risk Adjustment and Financial Strategies in Managed Care Organizations. Health Administration Press, Ann Arbor, 2002. Tucker A, Weiner J, Honigfeld S, Parton R. AProfiling Primary Care Physician Resource Use: Examining the Application of Case-Mix Adjustment.@ Journal of Ambulatory Care Management. 1996; 19(1): 60-80. Verhulst L, Reid RJ, Forrest CB. AHold It - My Patients are Sicker! The Importance of Case Mix Adjustment to Practitioner Profiles in British Columbia.@ BC Med Journal. July/August 2001; 43(6): 328-333. Weiner J. AAmbulatory Case-Mix Methodologies: Applications to Primary Care Research.@ In Grady, M. (ed) Primary Care Research: Theory and Methods USDHHS Agency for Health Care Policy and Research. 1991; AHCPR Publication #91-0011, Rockville, MD. A-7 Weiner, J, Dobson A, Maxwell AS, Coleman K, Starfield B, Anderson G. 1996. ARisk-Adjusted Medicare Capitation Rates Using Ambulatory and Inpatient Diagnoses.@ Health Care Financing Review. Spring 1996;17(3), pp. 77-99. Weiner JP, Starfield BH, Lieberman RN. AJohns Hopkins Ambulatory Care Groups: A CaseMix System For UR, QA, and Capitation Adjustment.@ HMO Practice. 1992; 6(1): 13-19. Weiner J, Starfield B, Steinwachs D, Mumford L. ADevelopment and Application of a Population-Oriented Measure of Ambulatory Care Case-Mix.@ Medical Care. 1991; 29(5): 452472. Weiner J, Starfield B, Stuart M, Powe N, Steinwachs D. AAmbulatory Care Practice Variation Within a Medicaid Program.@ Health Services Research. 1996; 30: 751-770. Weiner J, Tucker A, Collins A, Fakhraei H, Lieberman R, Abrams C, Trapnell G, Folkmer J. AThe Development of Risk-Adjusted Capitation Payment System For Medicaid MCOs: The Maryland Model@ Journal of Ambulatory Care Management. January, 1998. Weyrauch K, Boiko P, Feeny D. AHMO Family Physicians: Men and Women Differ in Their Work.@ HMO Practice. 1995; 9(4): 155-161. Willson DF, Horn SD, Hendley JO, Smout R, Gassaway J. AEffect of Practice Variation on Resource Utilization in Infants Hospitalized for Viral Lower Respiratory Illness.@ Pediatrics. October 4, 2001, 108(4): 851-855. http://www.pediatrics.org/cgi/reprint/108/4/851.pdf Woolf SH, Rothemich SF, Johnson RE, Marsland DW. ASelection Bias from Requiring Patients to Give Consent to Examine Data for Health Services Research.@ Archives of Family Medicine. November/December, 2000; 9(10):1111-1118. A-8
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