® Paracetamol BP + DL-Methionine BP Description: Paracetamol 500mg & Methionine 100mg Tablet is a fast acting and safe analgesic with marked antipyretic property. Pharmacology: Paracetamol produces analgesic action by elevation of the pain threshold and antipyresis through action on the hypothalamic heat regulating center. Paracetamol is rapidly and completely absorbed from the GIT following oral administration. The mean half-life of absorption from the upper small intestine is only 7 minutes. The drug is extensively metabolized in the liver and it has a plasma half life of 1.5 to 3.0 hours. Paracetamol is not bound to plasma proteins to any extent. DL-Methionine is used to prevent liver damage in acetaminophen poisoning. It is also used for increasing the acidity of urine, treating liver disorders, and improving wound healing. Indications: All conditions requiring relief from pain and fever such as neuritis, neuralgia, headache, earache, toothache, pain due to rheumatic disorder, cold, influenza, dysmenorrheal pain, post-vaccination pain and fever of children etc. Dosage and Administration: Adults: Take one or two, every four hours. Maximum dose: Do not take more than 2 tablets at any one time. Do not take more than 8 tablets in 24 hours. Contraindications: Contraindicated for liver diseased patients. Precautions: Severe renal or liver impairment, pregnancy and lactation. Use in Children: Not recommended for children under 12 years old. Side Effects: Side effects are significantly mild, though hematological reactions have been reported. Pancreatitis, skin rashes, and other allergic reactions occur occasionally. Commercial Packs: Each Box containing 10 Alu-PVC blister strips of 10 tablets. ® Trade Mark Manufactured By Renata Limited Rajendrapur, Gazipur, Bangladesh.
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