FOR IMMEDIATE RELEASE For more information: Richard Spaziano PharmLogic, LLC (401) 738-0215 rspaziano@pharmlogic.co PharmLogic Announces Sponsored Research Agreement with Boston University Warwick, R.I. (February 26, 2014) – PharmLogic, LLC has entered into a Sponsored Research Agreement with Boston University to fund the research of Chemistry Professor Scott Schaus and Biology Professor Ulla Hansen in developing a targeted therapy to treat hepatocellular carcinoma (HCC), one of the most common cancers. The incidence of HCC is increasing despite a decrease in overall incidence of all cancers. Professors Schaus and Hansen reported in the Proceedings of the National Academy of Science their discovery of a new protein target for chemotherapy in the treatment of liver cancer—the transcription factor LSF. The coinvestigators identified small molecules that inhibit LSF cellular activity, and in turn growth of the cancer. Drs. Schaus and Hansen will be furthering their research in this area in collaboration with PharmLogic over the next year. “We are pleased to be involved in this most worthwhile cancer project in collaboration with exceptional researchers Drs. Schaus and Hansen,” said PharmLogic CEO, David Corvese, “With the addition of this project, PharmLogic is now developing nine different products, three of which have a cancer indication” Professor Schaus received his B.A. in Chemistry, summa cum laude, from Boston University in 1995 and a Ph.D. in Organic Chemistry from Harvard University in 1999. He joined the faculty of Boston University in the fall of 2001. Professor Hansen received her A.B. in Chemistry from Oberlin College in 1974, and a Ph.D. in Biochemistry and Molecular Biology from Harvard University in 1979. After 15 years on the faculty of Harvard Medical School and the Dana-Farber Cancer Institute, she moved to Boston University in 1998. Drs. Schaus and Hansen joined forces a couple of years ago to focus on the mechanisms of cell growth as it relates to the potential treatment of liver cancer, for which there has been no effective, systemic treatment. About PharmLogic, LLC PharmLogic supports innovation and entrepreneurship in healthcare. It manages a diverse intellectual property portfolio on behalf of equity investors that include institutions, foundations, family offices and individuals. PharmLogic works with universities, research hospitals, laboratories and other intellectual property developers to advance new pharmaceutical treatments and medical device technologies through the development process to reach Phase I/II clinical trials, licensing agreement or liquidity event. For more information, visit www.PharmLogic.co. About Boston University 85 Toll Gate Road | Warwick, RI 02886 | Phone: (401)738-0215 | rspaziano@pharmlogic.co Founded in 1839, Boston University is an internationally recognized institution of higher education and research. With more than 33,000 students, it is the fourth-largest independent university in the United States. BU consists of 16 schools and colleges, along with a number of multi-disciplinary centers and institutes integral to the University’s research and teaching mission. In 2012, BU joined the Association of American Universities (AAU), a consortium of 62 leading research universities in the United States and Canada. - ### - 85 Toll Gate Road | Warwick, RI 02886 | Phone: (401)738-0215 | rspaziano@pharmlogic.co
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