How to Do a Cementless Hip Arthroplasty Klaus-Peter Günther, Firas Al-Dabouby, and Peter Bernstein Introduction Since the early 1960s, when Sir John Charnley was performing cemented total hip replacement (THR) regularly with good results, techniques and component designs have been improved substantially. At that time THR was mainly an operation for elderly patients crippled with arthritis. Today, however, young patients with hip disease increasingly hope to restore their quality of life, which typically includes physically-demanding activities. As cement fixation can break down over time, there has been considerable effort and research especially in trying to enhance the methods of fixation. The goal was to create a living type of bond between implant and bone, which would be longer-lasting and stronger than the cement-bone-interface. Advances in bioengineering technology have driven the development of cementless hip implants with textured surfaces, which allow bone ingrowth. Recent studies suggest, that uncemented hips can provide durable fixation as well as cemented implants. In addition, better materials and designs have allowed the use of large-diameter bearings which provide an increased range of motion with enhanced stability and very low wear. Less invasive surgery can limit soft-tissue damage and might facilitate accelerated discharge and rehabilitation. Currently, studies are being performed to evaluate whether computerassisted surgery can contribute to reproducible and accurate placement of implants, which is still a crucial factor for long-term survival especially in uncemented THR. We will briefly describe the different anchorage concepts of the most popular uncemented implants and available Klaus-Peter Günther () Department of Orthopaedic Surgery, University Hospital Carl Gustav Carus Dresden, Fetscherstr. 74, D-01307 Dresden, Germany e-mail: klaus-peter.guenther@uniklinikum-dresden.de bearing materials. Then – after an overview on widely-used surgical approaches – a very basic description of implantation technique, potential complications and rehabilitation principles is provided. In order to compare different implant and approach philosophies, a short summary of available long-term studies will be presented. As this lecture is focussing on conventional hip replacement, recent alternatives (surface replacement and shortstemmed implants such as “bone-preserving” prosthesis) are not discussed in depth. Implant Selection Cementless Acetabular Cups The rationale for cementless fixation lies in the surface structure of implant components that should allow bone ongrowth. To secure a long-term fixation of uncemented implants, two important factors must be provided: primary stability and secondary long-term osseointegration. Primary acetabular stability is obtained by either inserting pressfit cups (with or without additional screws) or inserting threaded cups (Fig. 1). To support osseointegration, most current implants are made of pure titanium or a titaniumaluminum alloy. A rough surface area – produced by corundum blasting, titanium-plasma spray, titanium balls, nets or other grid designs – is essential for osseointegration. To allow for any osseous ongrowth, a 20 μm minimum porosity is required. To actually achieve osseointegration and vascularization, porosity can be between 100 and 1,500 μm. During the recent years, hydroxyapatite (HA) coating has been advocated to improve and secure osseointegration. HA-coating achieves the closing of micro-defects in the implant-bone interface, thus preventing clefts for wear debris entry. G. Bentley (ed.), European Instructional Lectures. European Instructional Course Lectures 9, DOI: 10.1007/978-3-642-00966-2_19, © 2009 EFORT 189 190 Klaus-Peter Günther et al. Fig. 1 Cementless press-fit cup and stem with proximal fixation (left side); threaded cup and stem with meta-diaphyseal fixation (right side) Press-fit Cups Threaded Cups Most press-fit cups have a hemispherical design. The principle of implant press-fit is based on force transmission over the equator of the cup (mainly in the ilioischial direction) which requires: ● A 1–2 mm oversize of the implant diameter compared to the reamed bone bed. When this difference is missed (exact fit technique), additional screwing might be necessary to secure primary implant fixation. If the acetabular under-reaming exceeds 3–4 mm, the risk of acetabular fracture rises. ● A flat-bottom pole to avoid the rim bulging over the bony circumference. This design allows for a more tilt-secure position and is responsible for polar bone atrophy, which itself demonstrates the new force transmission balance. A circumferential closed bone rim avoids PE-distribution to the bone bed. ● A certain surface porosity that ensures additional primary stability through friction. The main advantage of threaded cups is an arbitrary selection of implant position, which can be helpful especially in acetabular protrusion or hip dysplasia with poor bone quality. Additionally hemispherical threaded cups require less bone resection than press-fit designs. Cup design and thread geometry are decisive for the implant performance during the screw-in process and positioning. A conical-shaped threaded cup guarantees high tilting stability and requires a less exact preparation of the bone bed [1]. However, threaded cup implantation requires good sensing of insertion torque slope and the final seating point to achieve optimal stability and avoid overturning. In addition a correction of cup position after the first threads – which can be still applied in press-fit cups – is not anymore possible. Some Surgeons prefer cups with additional stabilization through screws, pegs, rings, fins, spikes or hollow cylinders. These modifications, however, can alter the mechanical responses of the acetabular host bone significantly. Several stem designs are available on the market. The stem, is responsible for the fixation of the prosthesis and for transmitting forces to the bone. Therefore in nearly all stem types adaptive bone changes of the proximal femur can Cementless Stems How to Do a Cementless Hip Arthroplasty be observed after several years and they vary according to design geometry, biomaterials and surface texture. The types of fixation are epiphyseal (the femoral head is covered by a cup prosthesis), metaphyseal and meta-diaphyseal (with straight or anatomically-shaped monoblock-prostheses of different lengths, modular and custom-made prostheses) and diaphyseal (using predominantly modular systems). In primary cementless THR most stems are either straight or anatomically-shaped monoblock-prostheses, which rely on metaphyseal or meta-diaphyseal anchorage concepts (Fig. 1): ● Proximal (metaphyseal) fixation: The concept is based on the preservation of proximal bone and fixation without an attempt to fill the canal distally. Although many implants have been developed, one of the most popular representatives of this philosophy in Europe is the “Spotorno stem” [2]. It’s high initial stability depends on a series of flutes or ribs on the proximal anterior and posterior aspects of the tapered, straight, grit-blasted titanium stem which, with its rectangular cross-section, provides an interference fit in the femur. A slim diaphyseal part of the stem, without distal canal fill, leads to mainly metaphyseal load transfer without distal cortical hypertrophy as a result of stress-shielding. ● In contrast to the straight design of the Spotorno stem, several other prosthesis are anatomically-shaped. Although these stems with a mild curvature do not show a generally better survival, they are easier to implant with the antero-lateral and anterior approach. ● In recent years, short-stemmed prostheses have been developed, which claim neck-sparing and thus bonepreserving implantation. As this concept – as well as the resurfacing technique – is still under observation, we will not specifically address it within this article. ● Meta-diaphyseal fixation: The classic representative of this philosophy is the “Zweymüller” stem. This cementless, tapered, rectangular titanium stem was introduced in the early eighties and the concept is still very popular in Europe [3]. The rectangular geometry avoids the need to ream the femoral canal and advocators of this concept argue, that the conservative bone preparation reduces damage to the endosteal circulation. Cortical thickening, however, could be observed in severeal series and seems to be probably due to the concentration of focal stress in the transitional zone between the stiff area around the stem and the elastic area distal to the implant [4]. In spite of the frequency of this radiographic phenomenon, it is not related to stem loosening or inferior clinical outcome. 191 Stems with diaphyseal fixation are mostly modular and mainly used in revision surgery. For primary THR they offer an advantage of independent adjustment of anteversion, which can be important in deformed femora after a history of dysplasia or femoral osteotomy. Conical stems can also be implanted independent from the underlying femoral anteversion and might therefore be indicated in special situations. All implants should provide a possibility to reconstruct adequately the femoral offset. This can be obtained through stem designs with different neck-stem angles, different offset versions (regular and increased offset) or modular neck concepts. Although different implant materials are available, most cementless stems are made of titanium or titanium alloys. The flexibility of titanium stems seems to prevent severe stress-shielding, as the Young’s modulus of elasticity of titanium is near to human bone. More rigid implants made of other materials (e.g., cobalt-chromiumalloys) tend to produce higher rates of proximal stressshielding and distal cortical thickening especially with diaphyseal fixation. Most cementless stems have some kind of surface modification to enhance osseointegration. As in cementless cups a rough surface area – produced by corundum blasting, titanium-plasma spray, titanium balls, nets or other grid designs – can stimulate osteoblast activity. Additionally, some implants are also coated with Hydroxyapatite. As proximal bone stress-transfer has been thought to be less in association with proximally-coated stems as compared with extensively-coated stems, the latter have nearly disappeared from the market. Bearing Materials Survivorship of total joint arthroplasty depends on the durability of fixation and durability of articulation. Therefore not only the appropriate choice of cup and stem implants is important, but also the bearing material. In cemented THR, metal-on-polyethylene articular couple has been the most widely-used. Polyethylene wear, however, has been identified as a major factor adversely influencing the durability of joint replacement. Therefore alternative bearings with lower wear rates have been developed and they offer improved survival especially for young and active patients with higher life expectancy, where cementless THR might be indicated. All “hard-on-hard bearings” have been shown to be associated with reduced wear [5]. 192 Metal-on-metal bearings have wear rates that are 20–100 times lower than metal on conventional polyethylene. However, metal-on-metal articulations may lead to local adverse responses (metallosis) and increased systemic levels of cobalt and chromium. Therefore patients with kidney dysfunction, child-bearing age or known metal sensitivities should not receive these couplings. Ceramic-on-ceramic bearings have been in clinical use for nearly 40 years. The wear rates are also very low, but potential disadvantages are the risk of component fracture (especially rim fractures due to impingement in cup malpositioning) and audible squeaking in a small number of patients. Recently ceramic-on-metal bearings have been introduced, which address these risks. Finally “Highly Cross-Linked” Polyethylene bearings have evolved into the most frequently used bearing material for total hip arthroplasty. The liners can be combined with metal as well as ceramic heads and show significantly less wear than conventional polyethylene. Due to a still limited observation time, we do not know enough at the moment about potential long-term risks (i.e., ageing of the material). Although the combination of cups, heads and stems from different manufacturers is theoretically possible, it should be avoided! In case of material problems (i.e., early component fracture) medical device directives acknowledge the responsibility of a manufacturer only if his certified implants had been combined. If surgeons combine products from different manufacturers, they become liable for the “new product”. Surgical Technique Indication for Cementless Implants The first step of cementless THR is always to check the indication for this technique. Quantity as well as quality of host bone must be good enough to guarantee primary stability of the implant as well as susequent osseointegration. In patients with certain bone disorders or impaired bone metabolism (e.g., osteoporosis, osteomalacia) or a history of radiation exposure, initial bone strength and consecutive biological response might not be sufficient. With regard to the cup it must be considered if primary stability and circumferential bone contact can be achieved: ● Is the bone bed strong enough to resist the impaction force of a 1–2 mm oversized implant? ● Is there enough structural support to relay forces through the ischio-ilio-pubic columns of the acetabulum? Klaus-Peter Günther et al. ● Is there any defect (e.g., in a dysplastic acetabulum) which might impair primary stability through insufficient contact area? In order to achieve a proper stem position and long-term fixation, the following questions must be addressed: ● Is the cortical bone strong enough to resist proper broaching and impaction of a cementless stem? ● Is the shape of the medullary canal appropriate for the selected stem type? ● Can previous osteotomies prevent proper broaching and cortical stem contact? ● Does the design of the selected stem allow for adequate reconstruction of offset and leg-length? Generally, the implantation of cementless THR is more appropriate in younger than in elderly patients, although there are no evidence-based age limits. A definite indication can be the documented allergy against components of bone cement. Pre-Operative Planning Proper pre-operative planning and templating is one of the most important issues in THR. The choice of implants with adequate design and size depends on correct radiographs. For several reasons, an antero-posterior (a-p) view of the pelvis together with an axial view of the involved hip is mandatory. A weight-bearing a-p view of the pelvis allows grading of osteoarthritis, evaluation of acetabular as well as proximal femoral anatomy and proper measurement of leg-length discrepancies (together with the clinical investigation, which determines the presence of contractures). Modern computer programmes are offered for electronic templating (Fig. 2), but the elementary planning steps can also be performed very easily with appropriate drawing on template films (Fig. 3). Basic steps of planning are: ● Determination of correct hip centre: If possible, by projection from normal contra-lateral side. Alternatively, (in dysplastic hips with high dislocation), through determination of “true acetabular region” according to Ranawat (1980): A perpendicular line with a length of 20% of the pelvic height is plotted on the vertical of the Köhler line connecting the bottom of the teardrops. A parallel line of the same length is then drawn laterally, starting from the most proximal point of the first segment. Finally, the end-points of these two segments are connected with a line. The triangular area enclosed by these lines defines the anatomically correct acetabular region (Fig. 4). How to Do a Cementless Hip Arthroplasty Fig. 2 Pre-operative planning: example of electronic templating in a patient with hip osteoarthritis after failed pelvic osteotomy Fig. 3 Conventional pre-operative planning in a patient with secondary hip osteoarthritis due to developmental dysplasia 193 194 a Klaus-Peter Günther et al. b Fig. 4 (a) Estimation of correct hip centre and “true acetabular region” (see pre-operative planning) in a patient with hip dislocation due to acetabular dysplasia. (b) Post-operative radiograph with reconstruction of correct hip centre via implantation of bone- and screw-augmented press-fit cup and conical stem ● Selection of appropriate cup size and position. ● Definition of femoral shaft axis and appropriate neckshaft angle (off-set). ● Determination of neck resection level and leg-length adjustment. exposure of the acetabulum, facilitating cup positioning which may decrease rates of dislocation and the decreased risk of sciatic nerve injury which is not close to the operative field. Critics of the direct lateral approach suggest that the violation of the hip abductors may lead to delay in recovery of abductor strength and late Trendelenburg gait. The antero-lateral approach addresses the intermuscular plane between the gluteus medius and tensor fascia lata. The vastus lateralis muscle is left undisturbed. This approach provides sufficient anatomic orientation and exposure with minimal dissection and without excessive retraction. There is no danger of injury to the superior gluteal nerve or its branches. Due to the intact attachment of the gluteus medius, however, the insertion of straight stems (and reamers) can be difficult and might put the muscle under pressure. With this approach the implantation of so-called “anatomic” (curved) stems is preferred. The anterior approach between sartorius and tensor fascia latae muscles is avoiding any tension on the abductors at all. The acetabular exposure is very good and even the femur can easily be accessed with the hip in extension and/ or traction. Care must be taken to avoid damage of cutaneous femoral nerve branches. It is claimed that minimally-invasive surgical approaches for THR reduce soft-tissue trauma, decrease post-operative pain and blood loss, speed-up recovery and reduce the length of the hospital stay. These new procedures either use one small 6–10 cm incision through a posterior, lateral, Choice of Surgical Approach Many different surgical approaches to the hip joint have been described. Currently, THR is most commonly performed via a posterior, an antero-lateral or a direct lateral (transgluteal) approach. Anterior as well as medial approaches are possible, but not as popular. The posterior approach is considered to be associated with less problems regarding gait, since the abductor muscles are not dissected and damage to the superior gluteal nerve is very unlikely. Disadvantages are a less reliable cup positioning and increased rates of dislocation. Adequate soft tissue repair by re-attachment of posterior capsule and external rotators, however, greatly reduces the relative risk of dislocation using the posterior approach. In the lateral approach a longitudinal incision of the fibres of the gluteus medius and minimus and the vastus lateralis muscles takes advantage of the tendinous junction of these muscles over the greater trochanter. The incision should not be extended too far cranially in order to protect the superior gluteal nerve. Proposed advantages are the good How to Do a Cementless Hip Arthroplasty 195 Fig. 5 Simultaneous bilateral hip replacement through a minimally-invasive (anterior) approach. (a) Pre-operative and (b) postoperative radiographs antero-lateral or anterior approach. The “two-incisionapproach” (a short posterior incision for placement of the femoral component and an anterior incision for placement of the acetabular component) is more popular in the U.S.A. than in Europe. Controversy exists on whether these small incision THRs are actually minimally-invasive. It is debated whether a small skin incision that requires the application of high forces on the soft tissues for exposure of the joint but less muscle dissection will produce less overall trauma to the patient than a larger incision with wider muscle dissection but with lower retraction forces. Another question is whether decreased visualization provided by these techniques can ensure proper implant position and prevent neurovascular complications. A review of the literature to date provides no convincing evidence of any significant advantages of small incision THR compared with standard incision THR other than a shorter surgical scar [5]. There is also little evidence of the benefit of one minimallyinvasive approach over another in the literature. We have recently performed a prospective randomized trial to compare the functional outcome of two different less-invasive approaches (anterior and antero-lateral) with the conventional lateral approach and could only observe minor functional differences [6]. We therefore offer surgery through a minimally-invasive approach mainly for patients who demand this technique as well as in patients with bilateral simultaneous hip replacement (Fig. 5). Basic Surgical Steps in Cementless THR As the sequence of surgical steps depends at least partially on the selected approach, we describe more general aspects of cup and stem implantation and give some additional remarks referring to different approaches when indicated. Cup First or Stem First? Most surgeons tend to perform a stepwise approach with preparing and implanting the acetabular cup first followed by broaching and implanting the femoral stem. While the acetabular component inclination is relatively independent from femoral geometry and should be targeted between 30 and 50° (“safe zone” according to Lewinnek et al. [7]), proper anteversion of the cup depends at least partially on the amount of femoral version. In cementless THR the positioning of the stem with regard to anteversion or retroversion is more limited than in cemented implantation techniques, as uncemented stems must follow the natural geometry of the medullary canal to a certain degree. Therefore some surgeons prefer to broach the proximal femur after neck osteotomy first and to estimate the stem anteversion before implanting the acetabular cup. This offers the opportunity to adjust an appropriate cup anteversion in cases with abnormal femoral version and to avoid impingement and/or dislocation. Femoral Neck Osteotomy After the capsule of the hip joint has been exposed, a capsulotomy is performed with an electrical knife. In anterior, antero-lateral and lateral approaches the anterior portion of the capsule can be excised. In the posterior approach the incision should leave an intact capsular flap – together with the released tendons of the short external rotators – which can be repaired at completion of arthroplasty. The femoral head is then dislocated (depending on the approach anteriorly or posteriorly), and the neck of the femur is osteotomized at the pre-determined level. In cases where the femoral head is deformed or enlarged, it can be broken into fragments to facilitate removal, removing the 196 head piece by piece. Another alternative is to perform two parallel cuts through the neck and remove the fragment inbetween the cuts first. This can reduce tension and allows removal of the head easily. Then the distance between the lesser trochanter and the performed cut is controlled by palpation in order to check whether the pre-operatively planned level of neck osteotomy has been realized. This is also a good moment to perform an additional release of tight capsular remnants or contracted short external rotators in anterior, antero-lateral or lateral approaches if necessary. The femoral head should be kept for potential grafting purposes during the following procedure. Preparation of the Acetabulum and Cup Implantation Long, curved, narrow, sharp Hohmann retractors are applied to the anterior wall and the inferior acetabular notch, and the femur is retracted posteriorly (in anterior, antero-lateral and lateral approaches) or anteriorly (in the posterior approach). Most surgeons now excise the capsule entirely from the antero-superior rim and remove the labrum. It is essential to get full exposure of the acetabular rim and the transverse ligament in order to reach an optimal position of the cup. To get an estimation of the adequate reaming depth, the acetabular fossa can be considered as reference point and therefore should also be cleared of soft tissues. Sometimes a chisel has to be used to remove osteophytes. The acetabulum is prepared using spherical reamers of increasing diameter. In routine cases we use reamers with outside diameters measuring from 44 to 68 mm, incrementing 2-mm at each step. We start always with a 44 mm reamer, which is pointing centrally to the bottom of the acetabulum. Once central exposure of cancellous bone is achieved, we continue with progressively larger reamers to remove the subchondral plate until enough cancellous bone with adequate blood supply is exposed. This ensures necessary activity of inflammatory mediators and bone-forming cells in contact with the implant surface as a pre-requisite for sufficient bone ongrowth. In average cases a penetration of the rim/circular wall as well as the acetabular floor should be avoided. The better the remaining bone stock, the better will be cup stability and secondary osseointegration. In acetabular dysplasia, however, a mild medialisation of the cup even with a perforation of the medial wall is proposed by some surgeons. In order to avoid cranialization of the implant, the inferior margin of the last reamer should be level with the transverse ligament. After a horizontal direction of the first 1–2 reamers (to ensure distal positioning) the remaining Klaus-Peter Günther et al. reamers are angulated at an inclination angle (abduction) of about 45°. Prior to acetabular reaming the corresponding diameter of the last reamer to the planned cup size must be checked (depending on implants and bone quality some manufacturers propose over- or even under-reaming by 1 or 2 mm in order to achieve stable cup seating). When the desired reaming depth has been reached and inspection confirms appropriate bone quality, a trial cup can be inserted to check adequate positioning. The trial cup – as well as the definitive implant – should be positioned according to the “safe zone” [7]. ● Inclination of 30–50° with reference to the transverse teardrop line (higher inclination can lead to excessive loading at the superior edge with liner wear and/or instability) ● Anteversion of 10–30° depending on the anticipated antetorsion of the femoral components (less anteversion can lead to ventral impingement in flexion and/or dorsal instability, higher anteversion can lead to ventral dislocation) Once an acetabular trial component – which should fit snugly – is placed to assess the coverage and optimum position, image intensifier control can be performed. This is especially helpful in obese patients where the position on the operating table is difficult to determine. In a dysplastic acetabulum the lateral coverage can be insufficient. If less than 70% of the trial component is in contact with bone, the stability can be improved by performing bony augmentation. For that purpose an appropriate cortico-cancellous fragment is cut out of the femoral head and fixed to the cranial wall with two screws (Fig. 6). It might also be necessary to remove inflamed synovial tissue from arthritic cysts. If the cysts are large enough, grafting by cancellous bone chips out of the preserved femoral head can be performed. After removal of debris the definitive implant can be seated. Press-fit cups are impacted with a heavy hammer. During impaction, one should be aware of the correct position and angulation. If in doubt, the position of the patient on the table is checked again and even fluoroscopy can be performed. Confirmation of stable seating is achieved by a combination of acoustic (sound change during impaction) and tactile indicators (increasing resistance of the impactor against manual movements). Some cup designs allow checking the approximation towards the central bone bed through the impactor’s screw-hole. One should not try to maximize stability by overhammering as this will eventually result in loosening or acetabular fracture. Adaption of pelvic bone to raising mechanic stress can be supported by waiting intervals between repeated hammerings. How to Do a Cementless Hip Arthroplasty 197 a f b d c e Fig. 6 Bony augmentation of the acetabulum in a patient with unilateral osteoarthritis due to hip dysplasia (a) primary reaming in the true acetabular region (b) would lead to insufficient cranial acetabular coverage of the cup (c). Screw fixation of a cancello-cortical fragment retrieved from the deformed femoral head (d) results in circular bony augmentation and adequate stability of the cup (e, f) 198 Klaus-Peter Günther et al. If no stable implant fixation can be achieved, the following potential reasons should be checked: ● Is there still enough stable bony support on the anterior, posterior and cranial rim? ● Has an acetabular fracture appeared? ● Has the right implant size been chosen? ● Was the impact position (angulation) of the implant identical with the desired position? ● Does soft tissue prevent bony contact? ment of the liner against the neck of the stem, which is especially critical for hard bearings. Prior to impaction of the liner, the shell must be thoroughly cleaned and soft tissue remnants at the circumference removed. After impaction check carefully circumferential seating of the liner and stable fixation. If no distinct reason for insufficient stability can be identified and the bone stock is good enough, repeated reaming to a deeper position with the finally-used size can be tried. A larger cup size or mild reduction of anteversion (to get better dorsal support) can also be tried, if no fracture has occurred. Some surgeons propose the application of additional screws to enhance stability and many implants provide screw holes for that purpose. Those screws should be placed in the direction of the main force vector and not override the medial wall nor the ischial foramen to avoid injury of major vessels and nerves. We should be aware of the fact, however, that additional screws change the pelvic strain distribution (thereby potentially influencing secondary osseointegration) and can lead to backside wear (particle transport through screw holes). Finally a grossly unstable cup will never be sufficiently fixed by augmenting screws. Threaded cups require basically the same acetabular preparation as press-fit cups. The definitive implantation process is somewhat different, however. Because of thread geometry it is not possible to correct implant angulation during turning the cup. As the threads support good stability very early during impaction, sensing of the correct seating point is the most critical part of cup implantation. In hemispherical designs it is more demanding to maintain the correct angulation during turning than in conical cups. Achievement of correct seating point and angulation, however, will always require a certain learning curve in threaded as well as in press-it cups. Exposure of the femur depends on positioning of the patient and surgical approach. In anterior and lateral approaches, the leg is externally rotated, in the postero-lateral approach (lateral position) the leg is turned inwards (up to 90°) together with bending and adduction of the hip. It is generally recommended to bend the knee joint 90° in order to use the lower leg as a reference line for appropriate anteversion. A short, narrow Hohmann retractor is applied to the posterior aspect of the femur to protect the soft tissues and the skin from damage during rasping. The femoral canal is mostly prepared using a canal finder and a series of chipped tooth broaches which increase in size. The canal finder (sometimes an awl) has to be inserted laterally and slightly dorsal in order to avoid varus positioning of the stem. A good estimate for the entry point is the piriformis fossa as it is normally in line with the medullary canal. To prepare the entry point, most manufacturers provide a chisel, which removes a corticocancellous bone block from the neck. While pushing the canal finder (awl) into the medullary cavity, it must be pressed in the direction of the greater trochanter. In straight stems it is sometimes even necessary to remove a small piece of the trochanter base from the femoral neck, as the medullary cavity has to be opened more from dorsally than in anatomic (curved) stems. In hips with a deformation of the trochanteric region (i.e., after proximal femoral osteotomy) anatomic stems can be easier to implant than straight stems (Fig. 7). Then the bed for the stem is prepared, using rasps of increasing size, until the highest possible degree of stability is obtained. Mostly this process is started with the smallest rasp available. Curved handles or even off-set handles help to avoid contact with soft tissues. With the first rasp, care must be taken, to ensure a correct anteversion (usually 10–15°). This is necessary, as the sum of femoral and acetabular anteversion should aim at 20–30° (in posterolateral approaches even a little bit more). Constant bending of the lower leg (90° flexion in the knee joint) helps to determine the desired anteversion very precisely. In patients with pathological anteversion or retroversion, a second osteotomy more distal towards the lesser trochanter or Liner Choice Most cup implants offer several liner options (conventional Polyethylene as well as hard bearings). The choice depends on patient’s age and activity as well as Surgeon’s preference. Modern liners offer the advantage of optional elevated lips and compatibility with different head ball sizes (mostly 28–36 mm) in order to improve the range of motion and reduce wear. It must be re-emphasized, however, that wrong cup position can lead to edge loading and impinge- Preparation of the Femur and Stem Implantation How to Do a Cementless Hip Arthroplasty 199 a b Fig. 7 Choice of femoral stem type: in hips with a deformity of the trochanteric region after femoral osteotomy (a), anatomic stems might be easier to implant than straight stems (b) removal of some cortical bone may be necessary. Another option in these cases is, to change the prosthesis system and implant a conical stem, which allows free rotation (Figs. 4b and 6f). Progressive and step-wise rasping with increasing dimensions now compresses the cancellous bone. The rasps are inserted with small hammer blows and care is taken not to fracture the cortex. If it is necessary, the cortex can even be reamed. The desired stability of cementless stems is based on a press-fit-concept in cortical and cancellous bone. It is therefore very important to get the best press-fit possible. Undersizing of the stem must be avoided, as this can lead to subsidence and loosening over time. On the other hand, oversizing bears the risk of damaging cortex stability, which can lead to an intra-operative or early postoperative fracture. If a stable position of the final rasp has been reached, it must be checked to ensure that the distance between the proximal shoulder of the prosthesis and the greater trochanter is equal to the pre-operatively templated position. If the actual distance is shorter, the neck osteotomy can be repeated in a lower position and a smaller rasp introduced. If the distance is higher than pre-operatively determined either a larger rasp with a less deeper position or a long neck can be tried. 200 This is the opportunity to check alignment with a trial reduction. For that purpose most systems offer trial necks of different length and/or off-set, which can be inserted into rasp holes after removing the handles. Once the trial neck which corresponds to the pre-operatively planned offset is selected, a trial head can be positioned. After reduction of the trial prostheses, three main issues should be checked: ● Range of motion ● Leg-length ● Stability Although this can be performed clinically, we also control the reconstruction under fluoroscopy. The radiographic evaluation allows us to document, if the pre-operatively planned off-set and leg-length reconstruction have been achieved. If the alignment has to be changed, a repeat trial with heads of different length (or even a different neck) is possible. The range of motion is checked to avoid bony impingement and instability. Depending on the surgical approach, especially external rotation in extension (anterior and lateral approaches) or internal rotation in hip flexion (posterolateral approach) should be performed in order to simulate anterior or posterior dislocation mechanisms. After removal of the rasp, a prosthesis of the appropriate size is inserted and driven into the medullary canal, until it is completely stable. This manoeuvre has to be performed with the necessary light touch, as most implants have a slightly larger dimension than the corresponding rasp. Because of the wedge mechanism an excessive load might be exerted in addition. This load on the neck cortex – or the greater trochanter when a straight stem is implanted – can lead to a fracture. It is therefore very important to adjust the force of the hammer blows according to the bone quality. The hammer blows should be stopped immediately, if a change in the sound of the blows from dull (cancellous bone) to sharp (cortical bone) is perceived. This is one of the most critical steps in cementless THR and can only be learned by experience. Rarely the stem needs to be removed intra-operatively (i.e., when the position after insertion is different from the previous rasp position). For this situation a specific extraction instrument should be available, which protects the neck and cone of the stem. Then the prosthesis can be used again after necessary changes (as for example repeated rasping) have been performed. After insertion of the stem, another trial reduction can be performed with a test head as before (especially if the final level of the imlant shoulder is different from the level of the rasp – indicating a different depth of insertion). Finally the taper must be cleaned and dried thoroughly, Klaus-Peter Günther et al. before the definitive femoral head is mounted and tapped into position. Before wound closure we perform another range-of-motion as well as final stability testing. A final fluoroscopic control serves as post-operative radiographic documentation of correct alignment and bone integrity. Computer Navigation Navigation is sometimes used in an effort to increase the accuracy and consistency of hip arthroplasty component position. Most recent studies have demonstrated equal or superior accuracy in association with the use of navigation systems as compared with manual techniques. It still has to be evaluated, however, if patients have any clinical benefit from that improvement and under which circumstances navigation is cost-effective. Therefore currently, navigated THR cannot be recommended as a routine procedure [5]. Peri- and Post-Operative Management Prophylaxis of Heterotopic Ossification To avoid heterotopic ossification it is crucial to protect the soft tissues throughout the whole procedure and to prevent the apposition of bone fragments around the joint. We therefore remove meticulously any debris from acetabular reaming and femoral rasping prior to insertion of the implants, trial reduction and final reduction. Additionally patients receive NSAIDs for 2 weeks post-operatively, if no contraindication exists. Peri-Operative Antibiotics As one of the major risks in THR is the development of peri-prosthetic infection, we deliver a single-dose prophylaxis with cephalosporine intravenously. Post-Operative Rehabilitation Our post-operative management in routine cases involves protected full weight-bearing (with crutches) for 3–4 weeks. After that time full weight-bearing without crutches is encouraged. Physical therapy is performed to strengthen the thigh and hip muscles. Depending on the surgical approach, certain muscles might need protection (i.e., re-attached external rotators in the postero-lateral approach or abductors in the lateral approach). In minimally-invasive anterior How to Do a Cementless Hip Arthroplasty or antero-lateral approaches there is no specific limitation of range of motion. Complications Generally, the complications of cementless THR are very similar to the comlications of cemented implantation tecniques. Therefore patients should be informed about specific risks of artificial joints (i.e., venous thromboembolic disease, damage of neurovascular structures, dislocation, peri-prosthetic infection, leg-length discrepancy, component loosening and heterotopic ossification). One specific issue is the prevalence of peri-prosthetic fractures, which seems to be higher in cementless THR: In a recent large cohort study risk factors associated with femoral fractures and their effect on femoral stem survivorship were determined. The incidence of proximal femoral fracture was 2.3%. Risk factors associated with fractures included an antero-lateral approach, uncemented femoral fixation and female sex. In case of intra-operative fracture most often cerclage wiring is sufficient. If the fracture occurs post-operatively, treatment depends on the type of fracture and stability of the implant. While mal-positioning of the acetabular cup can lead to edge load (increased wear), impingement and dislocation, the sequelae of stem mal-positioning are less clear. Some surgeons have observed that stem mal-positioning, particularly varus, has been associated with higher failure rates. Min et al., however, reviewed a consecutive series of THR’s performed with a cementless tapered-wedge stem and a mean duration of follow-up of 7.7 years, where the stem position was neutral in only 63% of the hips, valgus in 21% and varus in 16%. No revision was necessary, there was no difference in the three groups in clinical outcome (HHS or thigh pain) and similar bone re-modeling changes were observed in all patients, regardless of stem position [8]. Implant Survival The short- and medium-term results of modern cementless THR are normally good and similar to those reported after cemented THR, with respect to relief from pain and function. Mallory et al. reported on 2,000 consecutive arthroplasties with a tapered stem that were performed between 1984 and 2001. The rate of femoral stem survival was 98.6% at 5 years, 98.6% at 10 years and 96.6% at 15 years. 201 This success was attributed to the stem geometry and surface texture [9]. Long-term results with a follow-up of more than 10 years are only available for a limited number of uncemented implants. Aldinger et al. reviewed a series of cementless, double-tapered straight femoral stems (CLS) in 326 patients at a mean follow-up of 12 years (10–15 years). The mean age of the patients was 57 years (13–81). The overall survival was 92% and survival with femoral revision for aseptic loosening as an end-point was 95% [2]. The survival of cementless cups is still somewhat lower than the stem survival. Considering the mode of primary fixation, results between press-fit and threaded cups are still controversial [1, 10]. Using revision for any reason as an end point, 10–12 year survivorship rates from 93 to 99% and 15–18 year survivorship rates from 83 to 88% seem to be possible, especially in younger patients for both implant types [11–14]. In patient cohorts with uncemented implants many factors can influence survivorship, such as geometry, materials, surface finishes and bearings. Other factors including patient age and activity, surgical approach, expertise of the Surgeon and study design may also add to baseline differences between studies. Due to these limitations, National hip replacement Registries seem to be a valid instrument to compare the performance of different implants. In the most popular Swedish Registry the number of documented cementless THR is still significantly lower than the number of cemented arthroplasties. While the 10-year survival of all cementless prostheses in this registry is still somewhat lower than that of cemented prostheses, certain cementless implants show equal performance (i.e., CLS stems and Trilogy cups). In the Finnish registry a recent analysis at a mean follow-up of 12 years was performed [15]. The authors found that cementless THRs, as well as the stems and cups when analyzed separately, had a lower risk of revision for aseptic loosening than did the cemented THRs in patients with osteoarthritis who were 50–74 years-old. In patients who were 75 years of age or older, there were no significant differences in the results, other than the reduced risk of revision for aseptic loosening of hydroxyapatite-coated cementless cups compared with cemented all-polyethylene cups. Excessive wear of the polyethylene liner, however, resulted in numerous revisions of the modular cementless cups in patients who were 55–74 years-old. Thus, the long-term survival of the cementless THRs, with revision for any reason as the end-point, did not differ from that of the cemented THRs in any of the age groups. In conclusion, modern-design threaded and press-fit cups as well as cementless stems show promising survival 202 rates. With the increasing use of hard bearings especially in younger patients we can expect even further improvement. References 1. Effenberger H, Imhof M, Richolt J, Rehart S. Cement-free hip cups. Current status. Orthopäde 2004;33(6):733–50. 2. Aldinger PR, Breusch SJ, Lukoschek M, Mau H, Ewerbeck V, Thomsen M. A ten- to 15-year follow-up of the Cementlesse Spotorno stem. J Bone Joint Surg Br 2003;85-B:209–14. 3. Grübl A, Chiari C, Giurea A, Gruber M, Kaider A, Marker M, Zehetgruber H, Gottsauner-Wolf F. Cementlesse total hip arthroplasty with the rectangular titanium Zweymüller stem. J Bone Joint Surg Am 2006;88:2210–5. 4. Garcia-Cimbrelo E, Cruz-Pardos A, Madero R, Ortega-Andreu M. Total hip arthroplasty with use of the Cementlesse Zweymüller Alloclassic system: A ten to thirteen-year follow-up study. J Bone Joint Surg Am 2003;85:296–303. 5. Huo MH, Parvizi J, Bal BS, Mont MA. What’s new in total hip arthroplasty. J Bone Joint Surg Am 2008;90:2043–55. 6. Kirschner S, Witzleb WC, Krummenauer F, Mettelsiefen J, Günther KP. Early results of a prospective randomized controlled trial comparing a standard approach against two minimal invasive approaches in total hip arthroplasty. (manuscript in review). 7. Lewinnek GE, Lewis JL, Tarr R, Compere CL, Zimmerman JR. Dislocations after total hip-replacement arthroplasties. J Bone Joint Surg Am 1978;60:217–20. Klaus-Peter Günther et al. 8. Min BW, Song KS, Bae KC, Cho CH, Kang CH, Kim SY. The effect of stem alignment on results of total hip arthroplasty with a cementless tapered-wedge femoral component. J Arthroplasty 2008;23(3):418–23. 9. Mallory TH, Lombardi AV, Leith JR, Fujita H, Hartman JF, Capps SG, Kefauver CA, Adams JB, Vorys GC. Minimal 10-year results of a tapered cementless femoral component in total hip arthroplasty. J Arthroplasty 2001;16(8 Suppl 1): 49–54. 10. Reikerås O, Gunderson RB. Long-term results of HA coated threaded versus HA coated hemispheric press fit cups: 287 hips followed for 11 to 16 years. Arch Orthop Trauma Surg 2006;126(8):503–8. 11. Engh CA, Hopper RHJ, Engh CAJ. Long-term porous-coated cup survivorship using spikes, screws, and press-fitting for initial fixation. J Arthroplasty 2004;19(7 Suppl 2):54–60. 12. Gabbar OA, Rajan RA, Londhe S, Hyde ID. Ten-to twelveyear follow-up of the furiong hydroxyapatite-coated femoral stem and threaded acetabular cup in patients younger than 65 years. J Arthroplasty 2008;23(3):413–7. 13. Reigstad O, Siewers P, Røkkum M, Espehaug B. Excellent long-term survival of an uncemented press-fit stem and screw cup in young patients: follow-up of 75 hips for 15–18 years. Acta Orthop 2008;79(2):194–202. 14. Zweymüller KA, Steindl M, Schwarzinger U. Good stability and minimal osteolysis with a biconical threaded cup at 10 years. Clin Orthop Relat Res 2007;463:128–37. 15. Mäkela KT, Eskelinen A, Pulkkinen P, Paavolainen P, Remes V. Total hip arthroplasty for primary osteoarthritis in patients fifty-five year of age or older. An analysis of the finnish arthroplasy registry. J Bone Joint Surg Am 2008;90: 2160–70.
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