For the week of 10/13/2014...10/20/2014 10/10/2014 The text of the Salk Weekly Bulletin is available via the Internet. World-Wide Web users will find it on the Salk Institute Home Page (http://www.salk.edu/events/scientific_seminars.html). If you no longer need to be sent a hard-copy version of this bulletin, have questions about listed seminars, or wish to submit a seminar for inclusion in this list, please contact Inger Johnson at (858) 453-4100 ext. 1658 or send email to events@salk.edu. Please e-mail any seminar cancellations to events@salk.edu and they will be sent out to the e-mail adresses. Monday October 13, 2014 October 13 & 14: The Immune Epitope Database (IEDB) User Workshop La Jolla Institute for Allergy & Immunology Various Speakers Registration fee is $50 and space is limited - Applications due by August 25, acceptance notifications will be emailed on or before August 28. LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY Contact: workshop@iedb.org 11:00 am “Rethinking Asymmetric Synthesis: The Development of General MetalCatalyzed Cross-Coupling Reactions that Enable the Use of Optically Active Nucleophiles” Professor Mark R. Biscoe, The City University of New York Organic Seminar UNIVERSITY OF CALIFORNIA, SAN DIEGO NSB Auditorium (NSB 1205) Host: Jerry Yang x44466 Contact Angela Douglas, (858) 534-357, adouglas@ucsd.edu 1:00 pm “Surface Chemistry and Global Impacts of Particles from the Micro to Nano Scale” Professor Vicki Grassian, University of Iowa Special Seminar UNIVERSITY OF CALIFORNIA, SAN DIEGO NSB Auditorium (NSB 1205) Host: Kimberly Prather x25312 Contact Angela Douglas, (858) 534-357, adouglas@ucsd.edu The Salk Institute BULLETIN 10/13/2014...10/20/2014 Page 1 of 7 2:00 pm “How Dynamic Networks Affect Disease Transmission” Dr. Nina Fefferman, Dept. of Ecology, Evolution & Natural Resources, Rutgers University UNIVERSITY OF CALIFORNIA, SAN DIEGO Natural Sciences Building, Room 4211 Contact: Dr. Noa Pinter-Wollman, nmpinter@ucsd.edu 4:00 pm “Specificity of Regulatory T Cells that Modulate Vascular Inflammation: A New Mechanism for Intravenous Immunoglobulin (IVIG) Therapy” Alessandra Franco, M.D., Ph.D., Pediatrics, University of California, San Diego UNIVERSITY OF CALIFORNIA, SAN DIEGO Leichtag Biomedical Building, Room 107 Contact: Graham Ryan, grryan@ucsd.edu 4:00 pm “From NAFLD to NASH to Cirrhosis-New Insights into Disease Mechanisms” Ariel Feldstein, M.D., Rady’s Children’s Hospital, University of California, San Diego UNIVERSITY OF CALIFORNIA, SAN DIEGO Leichtag Biomedical Building, Room 107 Contact: Graham Ryan, grryan@ucsd.edu Tuesday 2:00 pm October 14, 2014 “Physicochemical Alterations of the Extracellular Matrix: Implications in Fibrosis and Cancer Metastasis” Dr. Shyni Varghese, Bioengineering Department, UC San Diego UNIVERSITY OF CALIFORNIA, SAN DIEGO Marilyn G. Farquhar Seminar Room (formerly CNCB) Contact: Cookie Santamaria, 858-534-1981, cookie@ucsd.edu 2:00 pm “A Paradigm Shift in Asymmetric Synthesis: Progress towards a General Metal-catalyzed Cross-coupling Reaction that Enables the Use of Optically Active Secondary and Tertiary Nucleophiles” Mark R. Biscoe, Ph.D., Assistant Professor, Dept. of Chemistry, The City College of New York THE SCRIPPS RESEARCH INSTITUTE BCC1 – W.M. Keck Foundation Amphitheater Host: Phil Baran, Ph.D. 4:00 pm “Unwiring the Brain: How Can We Get the Circuit Diagram and Why Would We Want It?” Winfried Denk, Max Planck Institute UNIVERSITY OF CALIFORNIA, SAN DIEGO Marilyn G. Farquhar Seminar Room (formerly CNCB) Host: Akinori Mitani Contact: Linh Vandermar, linh@ucsd.edu The Salk Institute BULLETIN 10/13/2014...10/20/2014 Page 2 of 7 4:00 pm “Reaction Dynamics of Transient Species: From Elementary Reactions to Nanoparticles” Professor Robert Continetti, University of California, San Diego Department Colloquia UNIVERSITY OF CALIFORNIA, SAN DIEGO NSB Auditorium (NSB 1205) Host: Department of Chemistry & Biochemistry Contact: Angela Douglas, (858) 534-357, adouglas@ucsd.edu 5:00 pm “UPR Activation Induces Site-specific Regulatory Ubiquitylation of Ribosomal Proteins that Comprise the mRNA Exit Tunnel” Eric Bennett – Bennett Lab (UCSD) Please RSVP @ http://doodle.com/7ni2a2bke22hkbxt Sanford|Burnham Medical Research Institute Fishman Auditorium Host: Randal J. Kaufman Contact: Debbie Signer, dsigner@sanfordburnham.org 5:00 pm "ER Stress Defines the Response of Tumor Cells to Chemotherapies via Control of Glutamine Metabolism by the Ubiquitin E3 Ligase RNF5". Young Ju Jeon - Ronai Lab (SBMRI) Please RSVP @ http://doodle.com/7ni2a2bke22hkbxt Sanford|Burnham Medical Research Institute Fishman Auditoriu, Bldg. 4 Host: Randal J. Kaufman Contact: Debbie Signer, dsigner@sanfordburnham.org Wednesday 9:00 am October 15, 2014 "Substrate-dependent Control of HAS3 Activity" Drs. Markku & Raiji Tammi, University of Eastern Finland Halozyme Therapeutics, Inc Host: H. Michael Shepard Contact: Kerstin Gottke, 858-704-8149, kgottke@halozyme.com 12:00 pm “Somatic Hypermutation Rather than Class Switch Recombination is Essential for the Establishment of Peripheral B Cell Tolerance” Eric RF Meffre, Ph.D., Associate Professor, Department of Immunobiology, Yale University LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY Ishizaka Seminar Room Host: Shane Crotty Contact: Priscilla Colby, pcolby@liai.org The Salk Institute BULLETIN 10/13/2014...10/20/2014 Page 3 of 7 4:00 pm “Industry Funding of Academics: Should We Be Concerned?” Wael Al-Delaimy, Professor and Division Chief of Global Health, Department of Family and Preventive Medicine UNIVERSITY OF CALIFORNIA, SAN DIEGO Medical Teaching Facility 175 Contact: Mary Devereaux, mdevereaux@ucsd.edu 4:00 pm “Epithelial Cell Turnover – New Roles for Mechanical Tension Driving Cell Death and Division” Jody Rosenblatt, University of Utah, Huntsman Cancer Institute UNIVERSITY OF CALIFORNIA, SAN DIEGO Marilyn Farquhar (formerly CNCB) Seminar Room Hosts: Jim Wilhelm & Kevin Corbett Contact: Jennifer Roth, jhroth@ucsd.edu Thursday 12:00 pm October 16, 2014 “Intrinsic and Extrinsic Regulation of Early B Cell Tolerance Checkpoints” Eric R.F. Meffre, Ph.D., Associate Professor, Department of Immunobiology, Yale University THE SCRIPPS RESEARCH INSTITUTE The Committee Lecture Hall Contact: Daniella Carlson, dcarlson@scripps.edu 12:00 pm “Explorations of Self: The Human Microbiome in Health and Disease” Professor David Relman, Stanford University Biochemistry Seminar UNIVERSITY OF CALIFORNIA, SAN DIEGO NSB Auditorium (NSB 1205) Hosts: Pieter Dorrestein and Ulrich Müller Contact Angela Douglas, (858) 534-357, adouglas@ucsd.edu 1:30 pm “Molecular Control of G Protein Mediated Neurotransmission” Kirill Martemyanov, Ph.D., Associate Professor, Dept. of Neuroscience, Scripps Florida THE SCRIPPS RESEARCH INSTITUTE BCC1 – W.M. Keck Foundation Amphitheater Host: Mark Mayford, Ph.D. The Salk Institute BULLETIN 10/13/2014...10/20/2014 Page 4 of 7 3:30 pm “Action and Regulation of MicroRNA-mediated Gene Silencing” Martin Simard, Ph.D., Associate Professor, Research Scholar Senior of Fonds de Recherche du Québec-Santé, St-Patrick Research Group in Basic Oncology, Oncology-CHU de Québec (Hôtel-Dieu de Québec), Laval University Cancer Research Center, Quebec, Canada The Cell and Molecular Biology Affinity Group Seminar Series THE SCRIPPS RESEARCH INSTITUTE The W.M Keck Foundation Amphitheater Host: Ian MacRae Contact: Ella Blanc (858) 784-8377, ellab@scripps.edu, and Ellen Fiss.(858) 784-7968 4:00 pm "This Is Your Brain on Music" Daniel J. Levitin, Professor and James McGill Chair in Psychology; Assoc. Mbr, School of Computer Science, Faculty of Medicine, Interdisciplinary Program in Neuroscience, Schulich School of Music, and Faculty of Education, McGill University; Dean, College of Arts & Humanities, Minerva Schools at Keck Graduate Institute SALK INSTITUTE FOR BIOLOGICAL STUDIES Conrad T. Prebys Auditorium, East building Host: Ursula Bellugi Contact: Nova Summers, 858-453-4100 x1615, nsummers@salk.edu 4:00 pm “Coordinating Catabolic and Anabolic Responses in Skeletal Muscle by the cAMP Signaling Pathway” Michael Conkright, Ph.D., Assistant Professor, Department of Cancer Biology, Scripps Research Institute - Florida SANFORD | BURNHAM MEDICAL RESEARCH INSTITUTE Bldg. 2, Room 2224 Host: Judith Altarejos Contact:Rebecca Kaercher, rkaercher@sanfordburnham.org Friday 8:00 am October 17, 2014 2014 Annual Symposium of the Institute for Genomic Medicine In Partnership with Illumina Presents: Genomics of the Single Cell See website for speaker list UNIVERSITY OF CALIFORNIA, SAN DIEGO Duane L. Roth Auditorium Contact: Darla Schell, dschell@ucsd.edu 9:00 am “Demethylases and Beyond” Gongyi Zhang, Ph.D., Associate Professor, Integrated Department of Immunology, National Jewish Health UNIVERSITY OF CALIFORNIA, SAN DIEGO Skaggs School of Pharm. & Pharm. Sci. Building RM 1182 Host: David N. Bailey Contact: Doreen Lacy, dlacy@ucsd.edu The Salk Institute BULLETIN 10/13/2014...10/20/2014 Page 5 of 7 10:30 am "Hyaluronan Synthesis in Breast Cancer" Drs. Markku & Raiji Tammi, University of Eastern Finland RSVP Deadline 10/16/14 Halozyme Therapeutics, Inc. Halozyme Therapeutics, Inc. (Torrey Pines Conference Center) Host: H. Michael Shepard Kerstin Gottke, 858-704-8149, kgottke@halozyme.com 11:00 am “Covalency Trends in Actinides” Dr. Stosh A. Kozimor, Los Alamos National Lab Inorganic Seminar UNIVERSITY OF CALIFORNIA, SAN DIEGO Pacific Hall, Room 4500 Host: Professor Joshua Figueroa x27478 Contact Angela Douglas, (858) 534-357, adouglas@ucsd.edu 2:00 pm “Close Species Comparative Genomics (CSCG): Tiger and Whale Genomes” Jong Bhak, Ph.D., Professor, Ulsan National Institute of Science and Technology Bioengineering 281 Seminar Series UNIVERSITY OF CALIFORNIA, SAN DIEGO Powell-Focht Bioengineering Hall, Fung Auditorium Contact: Pam Murphy, pmurphy@eng.ucsd.edu 4:00 pm "A Hidden, Parallel Universe of Non-coding RNAs - circRNA" Darren Jiang, Ph.D., Former CIRM intern (Louise Laurent) UNIVERSITY OF CALIFORNIA, SAN DIEGO Sanford Consortium for Regenerative Medicine (SCRM) Contact: Miles Wilkinson, mfwilkinson@ucsd.edu Monday 12:00 pm October 20, 2014 “Combating Mosquito Borne Infectious Diseases by Rational Design of Selective Insecticides” Cecilia Engdahl, Chemistry Department, Umeå University, Umeå, Sweden UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences Pharmacy School Building Room 1120 Host: Zoran Radić Contact: Doreen Lacy, dlacy@ucsd.edu 4:00 pm “From NAFLD to NASH to Cirrhosis - New Insights into Disease Mechanisms” Ariel Feldstein, MD, Professor of Pediatrics, Chief, Division of Pediatric Gastroenterology, Hepatology and Nutrition, University of California, San Diego UNIVERSITY OF CALIFORNIA, SAN DIEGO Leichtag 1st floor, Room 107 Contact Graham Ryan grryan@ucsd.edu or (858) 822-5650 The Salk Institute BULLETIN 10/13/2014...10/20/2014 Page 6 of 7 The Salk Institute BULLETIN 10/13/2014...10/20/2014 Page 7 of 7