Name: Pedro Michael Cavaleiro de Miranda Place of Birth: Cambridge, UK Date of Birth: 19 Sept. 1959 Nationality: Portuguese, British Address: Institute of Biophysics and Biomedical Engineering Faculty of Science, University of Lisbon Campo Grande 1749-016 Lisbon Portugal Tel: +351 217500177, +351 217500310 Fax: +351 217500030 E-mail: pcmiranda@fc.ul.pt Academic degrees: “Agregação em Engenharia Biomédica e Biofísica”, Faculty of Science, University of Lisbon, 2014 M.Sc., Computer Science, University College London, UK, 1992 Ph.D., Physics, University of Sussex, UK, 1987 B.Sc., Physics, University of Sussex, UK, 1981 International Baccalaureate, Lycée International de Saint-Germain-en-Laye, France, 1977 Present position: Associate Professor, Faculty of Science, University of Lisbon, since June 2014. Previous positions: Assistant Professor, Faculty of Science, University of Lisbon, 1993-2014. Senior scientist, Neuroelectrics Barcelona SL, Barcelona, 2011-2012. Coordinator of the Biomedical Engineering course (5 years, BSc+MSc), Faculty of Science, University of Lisbon, 2007-2011. Director, Institute of Biophysics and Biomedical Engineering, Faculty of Science, University of Lisbon, 2005-2011. 1 18-12-2014 Subdirector, Institute of Biophysics and Biomedical Engineering, Faculty of Science, University of Lisbon, 1999-2005. Research Fellow, Biomedical Magnetic Resonance Research Group, St. George’s Hospital Medical School, London, UK, 1987-1991. Research Fellow, Rutherford and Appleton Laboratory, Oxford, UK, 1985-1986. Main scientific area of research: Stimulation of excitable tissues Other scientific areas of interest: MRI, Medical Imaging Recent publications: 1. Miranda PC, Mekonnen A, Salvador R, Basser PJ, “Predicting the Electric Field Distribution in the Brain for the Treatment of Glioblastoma”, Phys Med Biol, 2014, 59:4137-4147. 2. Ruffini G, Fox MD, Ripolles O, Miranda PC, Pascual-Leone A, “Optimization of multifocal transcranial current stimulation for weighted cortical pattern targeting from realistic modeling of electric fields”, NeuroImage, 2014, 89:216-225. 3. Miranda PC, Mekonnen A, Salvador R, Ruffini G, “The electric field in the cortex during transcranial current stimulation”, NeuroImage, 2013, 70: 48-58. 4. Merlet I, Birot G, Salvador R, Molaee-Ardekani B, Mekonnen A, Soria-Frish A, Ruffini G, Miranda PC, Wendling F, “Simulation of tCS effects on cortical activity and subsequent scalp EEG signals”, PLoS One, 2013, 8(2): e57330. 5. Miranda PC, “The physics of effects of transcranial brain stimulation”, Ch. 29, in Brain Stimulation: Handbook of Clinical Neurology, AM Lozano and M Hallett, Editors. 2013, Elsevier Science. 6. Angelakis E., Liouta E., Andreadis N., Leonardos A., Ktonas P., Stavrinou L., Miranda P. C., Mekonnen A., Sakas D., “Transcranial alternating current stimulation reduces symptoms in intractable idiopathic cervical dystonia: A case study”, Neurosci Lett, 2013, 533: 39-43. 7. Ruffini G., Wendling F., Merlet I., Molaee-Ardekani B., Mekonnen A. , Salvador R., Soria-Frisch A., Grau C., Dunne S., Miranda P. C., “Transcranial current brain stimulation (tCS): Models and technologies”, IEEE Trans Neural Syst Rehabil Eng, 2013, 21(3): 333-45. 8. Márquez-Ruiz J., Leal-Campanario R., Sánchez-Campusano R., Molaee-Ardekani B., Wendling F., Miranda P. C., Ruffini G., Gruart A., Delgado-García J. M., 2 18-12-2014 “Transcranial direct-current stimulation modulates synaptic mechanisms involved in associative learning in behaving rabbits”, Proc Natl Acad Sci U S A, 2012, 109(17): 6710-5. 9. Wagner TA, Miranda PC, “Biophysical foundations of TMS and tES: from electromagnetic fields to neural response”, Ch. 5, in Transcranial Brain Stimulation, C Miniussi, W Paulus and PM Rossini, Editors. 2012, Frontiers in Neuroscience series, CRC Press. 10. Peterchev A. V., Wagner T. A., Miranda P. C., Nitsche M. A., Paulus W., Lisanby S. H., Pascual-leone A., Bikson M., “Fundamentals of transcranial electric and magnetic stimulation dose: definition, selection, and reporting practices”, Review Article, Brain Stimul, 2012, 5(4): 435-453. 11. Faria P., Hallett M., Miranda P. C., "A finite element analysis of the effect of electrode area and inter-electrode distance on the spatial distribution of the current density in tDCS", J Neural Eng, 2011, 8(6): 066017 (11 pp). 12. Salvador R, Silva S. Basser PJ, Miranda PC, "Determining which mechanisms lead to activation in the motor cortex: A modeling study of transcranial magnetic stimulation using realistic stimulus waveforms and sulcal geometry", Clin Neurophysiol, 2011, 122(4): 748-758. 13. Rossi S, Hallett M, Rossini PM, Pascual-Leone A and The Safety of TMS Consensus Group, "Safety, ethical considerations, and application guidelines for the use of transcranial magnetic stimulation in clinical practice and research." Clin Neurophysiol, 2009, 120(12): 2008-39. 14. Salvador R, Miranda PC, Roth Y, Zangen A, "High permeability cores to optimize the stimulation of deeply located brain regions using transcranial magnetic stimulation." Phys Med Biol, 2009, 54(10): 3113-28. 15. Miranda PC, Faria P, Hallett M, "What does the ratio of injected current to electrode area tell us about current density in the brain during tDCS?" Clin Neurophysiol, 2009, 120(6): 1183-7. 16. Silva S, Basser PJ, Miranda PC, "Elucidating the mechanisms and loci of neuronal excitation by transcranial magnetic stimulation using a finite element model of a cortical sulcus." Clin Neurophysiol, 2008, 119(10): 2405-13. 17. Miranda PC, Correia L, Salvador R, Basser PJ, “Tissue heterogeneity as a mechanism for localized neural stimulation by applied electric fields”, Phys Med Biol, 2007, 52(18): 5603-17. 3 18-12-2014 18. Miranda PC, Lomarev M, Hallett M, “Modelling the current distribution during transcranial direct current stimulation”, Clinical Neurophysiology, 2006, 117(7): 1623-29. 19. Miranda PC, “Basic electromagnetism”, in “Magnetic stimulation in clinical neurophysiology”, M. Hallett and S. Chokroverty, Editors. 2005, ButterworthHeinemann: Philadelphia, PA. pp. 1-15. 20. Miranda PC, Hallett M, Basser PJ, “The electric field induced in the brain by magnetic stimulation: a 3D Finite Element analysis of the effect of tissue heterogeneity and anisotropy”, IEEE Trans Biomed Eng, 2003, 50(9): 1074-85. 21. Castro-Caldas A, Reis A, Miranda PC, Ducla-Soares E, “Learning to read and write shapes the anatomy and function of the corpus callosum”, in “The Parallel Brain: the cognitive neuroscience of the corpus callosum”, E. Zaidel and M. Iacoboni, Editors. 2003, A Bradford Book, The MIT Press: Cambridge, MA. pp. 473-7. 22. Carvalho M, Miranda PC, Sales Luís ML, Ducla Soares E, “Neurophysological features of fasciculations potentials evoked by transcranial magnetic stimulation in Amyotrophic Lateral Sclerosis”, Journal of Neurology, 2000, 247(3): 189-94. 23. Carvalho M, Miranda PC, Falcão F, Jardim L, “Reproducibility of cortico_ motor threshold: some observations”, Muscle & Nerve, 1999, 22(4): 538-9. 24. Carvalho M, Miranda PC, Sales Luís ML, Ducla Soares E, “Cortical muscle representation in ALS patients: Changes over the disease evolution”, Muscle & Nerve, 1999, 22(12): 1684-92. 25. Castro-Caldas A, Miranda PC, Carmo I, Reis A, Leote F, Ribeiro C, Ducla-Soares E, “Influence of learning to read and write on the morphology of the corpus callosum”, Eur J Neurol, 1999, 6(1): 23-8. 26. Miranda PC, Carvalho M, Conceição I, Sales Luis ML, Ducla-Soares E, “A new method for reproducible coil positioning in transcranial magnetic stimulation mapping”, Electroenceph. clin. Neurophysiol., 1997, 105(2): 116-23. Patents: 1. "Coil for magnetic stimulation and methods for using the same" - NIH Patent numbers: WO200232504, EP1326681, AU2002229129, CA2425276, US2004078056, HK1056849, US 2008312706, JP 2008093466, AU 2912902 2. "Transcranial magnetic stimulation system and methods" - Brainsway Patent numbers: WO2006134598, US2006287566, AU2006257210, CA 2610991 4 18-12-2014
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