CONFIDENTIAL The BDW Blog A property of BDW Biotechnologies LLC Healthy animals through healthy scienceTM Business Plan Prepared February 2015 The Problem: The challenges facing a sustainable society are numerous. Climate change, agricultural practices, and energy policy are a few of the topics that often come up on the nightly news. In many cases, the opinion of the public on such issues conflicts with the scientific consensus (Fig. 1). . Sometimes this is relatively trivial, such as the recent trend to exclude gluten from one’s diet. In many cases, however, it’s absolutely key that the public understand where the scientific consensus is coming from. The United States, as a democratic society, involves all citizens in much of its decision-making. For that reason, we need a public educated on the facts surrounding controversial issues. Fig. 1: It is clear that the public and experts don’t agree on many issues key to America’s future. Scientists need to do a better job conveying to non-scientists why they hold the positions they do. Many people view scientists as ultra-liberal, politically-motivated and financially-motivated to hold certain opinions. Trust of experts is at an all-time low. Science is complicated stuff and it’s not necessarily easy to convey the complex reasoning behind certain positions to someone who isn’t initiated in the topic. There is opportunity in this: How can we make the facts behind popular scientific controversies more accessible? 2 The Proposed Solution: A Blog. A blog which discusses science, technology, the environment, and health, but in a way which is different from other sources of information on the internet: We will be: • • • • • • • Independent of large corporate interests Optimistic Intelligent Conversational Simple Community-connected Recognizant that sustainable ag is more complicated than “Ban GMO”! In the face of increasing politicization, most people have a strong confirmation bias. That is, they will only read that which confirms what they believe themselves to already know. This is a challenge for our enterprise. To overcome it, we will work with our opponents (“reaching across the aisle,” so to speak) in order to help drive traffic to the site. For instance, we will reach out to anti-nuclear power blogs to promote things we write that confirm their opinions, just as we reach out to nuclear power proponents. Encouraging traffic from such varied sources will, hopefully, open minds about the gray areas of science that affect us all. Another challenge is that science is a relatively unpopular topic for common readership. In other words, many folks who desire to read about science already do so via Popular Mechanics, Popular Science, or any number of science news websites on the internet. Since we want to reach out to people who don’t necessarily have a scientific background or a strong interest in learning about science, we will keep the writing style very accessible. We don’t want lingo driving away potential readership. Further, we will only display one post at a time. This way, visitors to our site do not feel overwhelmed. Many places on the internet have dozens or even hundreds of links and thousands of disconnected words on a single page. It only takes a split second to drive a visitor away. A simple article, a clean interface, and an earth tone color palette welcome visitors to our page. As a community-connected platform, BDW is represented on social media. Through our Facebook page and Twitter account (@BDW_Biotech, 306 followers as of 2/13/15), we will promote and advance our content. We are also partnered with certain animal shelters in the Twin Cities to use their image content on our site. In return, the images we use of adoptable animals are linked to the adoption pages for those animals. Such partnerships help us engage with a more general readership. 3 Some planned topics we intend to discuss include: Genetically-modified organisms: The central belief of BDW is that all of science, including genetic engineering, is nothing more than a tool. And like all tools, the ethical consequences associated with science are not intrinsic to the tool itself, but in how that tool is used. One does not call a philosophy good or bad on the basis of whether it was written with pen or pencil but on the basis of the ideas contained therein. In the same way, the BDW Blog seeks to describe technologies on an individual level without a priori bias. The GMO potato is evaluated on the data collected and on the changes made, not on the way in which those changes were made. Through plain language and a scientific bent, we hope to provide a truly neutral voice in the discussion on GMOs. This blog will be written for a popular audience and will not overemphasize unimportant scientific details at the expense of clarity. It is hoped that through this, we can educate people better about biotechnology and perhaps change popular attitudes about GMOs. Organic food: The topic of organic food is one that is deeply intertwined with GMOs. Nevertheless, many products are non-GMO and also outside the official definition of organic. This is why there has been an explosion in the recent popularity of the NonGMO Project, a certification program whose requirements are not as stringent as those of the official Organic program. Organic food is expensive to raise and usually has reduced yields relative to non-organic produce. Further, organic products often have reduced shelf life. So what are the benefits to Organic certification? To what degree is this food healthier? Probiotic, antibiotics, and other bacterial health issues: Bacteria have always been an important part of our lives, for good or for ill. For most of our existence, we were unaware that bacteria existed, instead attributing illnesses to any manner of other causes. When we discovered antibiotics, we began to use them with reckless abandon, and have now done to the point where they are losing effectiveness. We have altered the global bacterial population to our detriment. Further, we exclude bacteria from our lives as much as possible, painting with a broad brush when the response must be more nuanced if we are to survive. Though the negative effects of bacteria have long been known, the myriad positives of certain strains are just coming to light. There is good evidence which indicates that some probiotics, bacteria which confer a benefit when consumed, can be extraordinarily beneficial to the host. Why do we need probiotics, when we’ve never needed them before? The “sterilization” of our food supply, while having major positive effects on global health, has resulted in a major reduction in the variety of bacteria which are consumed. The latest science strongly implies that regular consumption of key bacterial strains can impact things like weight gain, emotional health, and digestive health. How can we best balance antibiotics, probiotics, and other human tools to best ensure a sustainable bacterial ecosystem? Energy policy: What’s the best way to provide the world with electricity? This should be a straightforward question, but every single method has significant benefits---and 4 significant drawbacks. Coal is cheap but polluting. Wind has no emissions, but is expensive and can have a significant impact on bird populations. Solar also has no emissions, but requires vast tracts of land to operate properly and may be unsustainable due to the extremely caustic pollutants used in panel manufacture and the limited supply of rare earth elements. There are also political issues involved, since by far the largest supplier of such elements is China. Nuclear is cheap and non-emitting, but evokes significant public fear and may only be suitable for geologically-stable regions. Which way do we go? Vaccines: Vaccine opponents are among the most recalcitrant of folks out there. Nevertheless, we hope to reiterate some of the correct information out there to counteract the volume of misinformation, and to change a few minds. There are many other issues which are relevant and will be discussed, but these examples are some of those which are closest to us as a team and impact society the most and are listed exclusively for the sake of brevity. It is hoped that the controversial and relevant nature of the topics we cover will help encourage readership. We also intend to address major scientific topics in the news that fall outside the scope of these areas. Competition: Of course, the general idea of a scientifically-focused blog or news site is nothing new. Some competing sites include: Food Babe (www.foodbabe.com): Vani Hari is one of the most read bloggers on the internet for her opinions and research into food and food safety. She tends to use scare tactics and misinformation to promote her work, which includes her website as well as a few books. She is neither a food expert nor a scientist of any kind. This likely adds to her appeal for some, but much of what she writes is patent nonsense, such as her dislike for thiomersal, a mercury-containing compound found in some vaccines (http://foodbabe.com/tag/mercury/). The amount of mercury in such vaccines is less than in the average serving of fish, but you’d never know it from Vani. The BDW Difference: Our topic range is broader than Ms. Hari’s. Also, we’re not out to scare people, and we’re not selling books of lies. We’re scientists who are passionate about science and scientific policy, but we’re just regular people. We can be just as approachable as the food babe about controversial topics without resorting to invention. Though I think we’ll have to work a bit on the sex appeal. Genetic Literacy Project (http://geneticliteracyproject.org/): These guys have the right idea. Their goal is scientific literacy, just as ours is. However, their website is fantastically 5 busy! They have literally dozens and dozens of links on the front page. It’s a great site to go to if you want to just read a thousand different articles about GMOs. The BDW Difference: Simplicity! We’re not proposing to set up a vast link aggregator, and again, we want to touch on more topics than just genetic engineering. We’d love to partner with the GLP, however, and will approach them when we have the content to do so. Nuclear Information and Resource Service (http://www.nirs.org/home.htm): These are dudes on a mission against nuclear power. They’re not necessarily seeking to educate from a neutral platform. The BDW Difference: Our agenda is scientific literacy about important issues. Just like the NIRS, we’ll address the negatives of nuclear power, but it’s also very important that we discuss the positives, considering that the scientific consensus holds that nuclear is the most viable option for the US today (http://www.theguardian.com/environment/2013/nov/03/climate-scientists-supportnuclear-power). There are many advocacy sites like this one for everything from banning GMOs to solar power. BDW is only on the side of scientific consensus. Of course, being different doesn’t mean that we don’t want to work with our competitors. In the end, we all want to make the world a better place. Our goal is not to destroy our opposition, but to work to share information and links. The BDW Blog isn’t the only part of BDW Biotechnologies. We originally envisioned it as something of a marketing activity, using continual new content to drive traffic to the site for our other activities (animal probiotics, not yet launched). However, we realized that that we also wanted to write about other subjects of import. As scientists, we are very passionate about how science impacts society. However, every day we see dangerous falsehoods and complicated issues that are promoted as simple truth. 6 Fig. 2: Is Organic food the best agricultural policy moving forward? Maybe not, but you’d never know it from the branding. Just like with vaccines and global warming, there’s a lot of mixed messages out there. It became clear the Blog was going to grow beyond our original ideas for how it would function. Instead of commercial SEO, we realized we wanted to discuss a lot of different ideas and found that the degree of exclusivity that our original concept required would be confining. The Blog might generate a profit, but more importantly, we hope it generates change. Business model: The Blog will not earn money for its first half year to year of operations. Traction must be secured before any attempt at monetization is made. Otherwise, it will be difficult to encourage growth, since monetization strategies usually involve some degree of inconvenience to the user. Whether it’s with paid posts, ads, or membership programs, earning money can detract from the user experience. When exponential growth slows, the BDW Blog will begin to run Google AdSense in order to sustain the operation of the website. With only one full-time partner in the endeavor to begin, and part-time partners delivering content in their spare time, overhead will be low. AdSense can be expected to deliver about $5/1000 visits. 7 FoodBabe.com, a blog with a similar subject area but different angle, gets about 500000 unique visitors a month, leading to optimistic projections of $2500/month if properly maintained. Of course, we realize that that readership goal is difficult to achieve, and really only need to cover operational costs. As an internet platform, scaling will be straightforward. If content demand exceeds the available pipeline, the hosting solution and website design have been chosen with growth in mind. Pilot Description: The pilot is presently active at BDWbio.com. Fig. 3: A screenshot of the pilot Blog page As of 2/14/15, we have placed only one entry on the Blog. This entry was designed as a technical test for the website and appears to be working successfully. We will keep the Blog at one post until Thomas, our resident computer scientist and IT guy extraordinaire, is satisfied that everything is working as it should. We anticipate that this will take between one week and two weeks, at which point we will begin adding additional, more meaningful content. After we have at least ten posts (or a readership of 1000 unique visitors/week, whichever occurs first), we will attempt to begin coordination with other sites on the internet, such as Cracked.com. Providing them with an article that they agree to publish can net a hundred thousand pageviews or more, as they send traffic directly to the author’s pages. We will submit articles to Digg.com and Reddit, link aggregators which 8 also have high traffic. By reaching out to authors of similar content, we can benefit each other mutually through references to each other’s articles. If traffic doesn’t grow as anticipated, we will vary the content to see what topics draw the most hits. We can then focus on these topics for a period of time. Cost summary: We need approximately six months of operating expenses. This includes $25/mo for website hosting and $100/mo for relevant software licenses. We would like access to stock photography libraries as well which is valued at $199/mo (shutterstock.com). This equates to about $2000. Team: The BDW team is a group of scientists and educators committed to sharing ideas responsibly. Our backgrounds are diverse but our mission is the same: to change minds with truthful writing by experts, and through this, to change how people regard science in the United States. There are six individuals on the team. Adam Woodruff, BS in physics and 2013 MS in chemical engineering from the U of M, has extensive experience with science and technology, and published several papers in the field of synthetic biology. Further, he has moonlit as a science tutor (biology, chemistry, math, and physics) for seven years. Yogesh Dhande is a doctoral candidate in chemical engineering at the University, focusing on genetic editing. Joshua Magnuson is an MBA student at Carlson and has a decade of experience with medical devices and FDA regulations. Joanna Mooney is a 2014 MS grad of the U of M in biochemistry and is now teaching at George Washington University. Chris Hartlage earned his undergraduate degree in biology from the University of Kentucky and is now pursuing an MBA with a focus on marketing from the University of Notre Dame. Thomas Harris is an IT specialist at Marathon Petroleum and has extensive website development experience. By leveraging our collective technical, business, and educational experience, the BDW team is well-equipped to provide accurate information in an accessible way and market it effectively. It’s a small step, but every effort counts when you’re talking about the titanic effort involved in changing popular attitudes on critically important subjects. In time, we will make a difference. 9
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