1. society

Continuing its long history of influential scientific publishing, Phil. Trans. R. Soc. B
publishes high quality theme issues on topics of current importance and general
interest within the life sciences, guest-edited by leading authorities and comprising
new research, reviews and opinions from prominent researchers. Each issue
aims to create an original and authoritative synthesis, often bridging traditional
disciplines, which showcases current developments and provides a foundation for
future research, applications and policy decisions.
COMMISSIONING EDITOR
Helen Eaton
EDITORIAL COORDINATOR
Ruth Milne
PRODUCTION EDITOR
Tom Lowen
EDITORIAL BOARD
Organismal, environmental
and evolutionary biology
Spencer Barrett
Nick Barton
Tim Benton
Isabelle Côté
Richard Cowling
Sandra Diaz
Luc-Alain Giraldeau
Patrick Keeling
Peter Keightley
Hanna Kokko
Elena Kramer
Stephen Simpson
Gabriele Sorci
Marcel Visser
Andrew Watkinson
Ziheng Yang
Cellular and developmental biology
Martin Buck
Stephen Cohen
Marie-Anne Félix
Jeremy Green
Brigid Hogan
Jack Kaplan
Narry Kim
Pierre Leopold
Portland Customer Services
Charles Darwin House
12 Roger Street
London WC1N 2JU
United Kingdom
T +44 20 7685 2444
F +44 20 7685 2468
E sales@portland-services.com
rstb.royalsocietypublishing.org
EDITOR
Linda Partridge
SUBSCRIPTIONS
In 2015 Phil. Trans. R. Soc. B
(ISSN 0962-8436) will be published
26 times a year. For more details of
subscriptions and single issue sales
please contact our fulfilment agent:
Ottoline Leyser
Verena Niggli
Peter Rigby
Dale Sanders
Krishnaswamy VijayRaghavan
Jean-Paul Vincent
Neuroscience and cognition
Colin Blakemore
Graham Collingridge
Andreas Engel
Barry Everitt
Tecumseh Fitch
Vittorio Gallese
Christian Keysers
Kristine Krug
Hanspeter Mallot
William Marslen-Wilson
Tetsuro Matsuzawa
Michael Petrides
Gary Westbrook
Xu Zhang
Min Zhuo
Health and disease
Jean-Laurent Casanova
Chetan Chitnis
Rodrigo Correa-Oliveira
Thomas Curran
Sunetra Gupta
Julius Hafalla
Jonathan Hodgkin
Edward Holmes
Dennis Lo
C. Jessica Metcalf
Cliona O'Farrelly
Anne O'Garra
Mario Recker
Andrew Wilkie
Alternatively, please contact our customer
service team at:
E sales@royalsociety.org
PRICES FOR 2015
Online
only
Online
and print
£ UK/Europe
and rest of World
£2,394
£3,351
€ Europe
€3,111
€4,355
$ US/Canada
and rest of World
$4,529
$6,340
SUBMISSIONS
For submission guidelines and access to
journal content visit:
rstb.royalsocietypublishing.org
Phil. Trans. R. Soc. B
ISSN: 0962-8436
© The Royal Society, 2015
Except as otherwise permitted under the
Copyright, Designs and Patents Act, 1988,
this publication may only be reproduced,
stored or transmitted, in any form or by any
other means, with the prior permission in
writing of the publisher, or in the case of
reprographic reproduction, in accordance
with the terms of a licence issued by the
Copyright Licensing Agency. In particular,
the Society permits the making of a single
photocopy of an article from this issue
(under Sections 29 and 38 of this Act) for an
individual for the purposes of research or
private study. Open access articles, which
are published under a CC-BY licence, may
be re-used without permission, but subject
to acknowledgement.
Cover image
Size, longevity, and the promise of comparative oncology; stepping into Peto’s Paradox. (Cover illustration prepared by Alice MacGregor Harvey, Medical Illustrator, MA, USA.)
Typeset in India by Techset Composition Limited. Printed in the UK by Latimer Trend.
This paper meets the requirements of ISO 9706:1994(E) and ANSI/NISO Z39.48-1992 (Permanence of Paper) effective with volume 335, issue 1273, 1992.
Phil. Trans. R. Soc. B (ISSN 0962-8436) is published 26 times a year for US$6340 per year by the Royal Society, and is distributed in the USA by Agent named Air Business, C/O
Worldnet Shipping USA Inc., 149-35 177th Street, Jamaica, New York, NY11434, USA. US Postmaster: Send address changes to Phil. Trans. R. Soc. B, C/O Air Business Ltd, C/O
Worldnet Shipping USA Inc, 149-35 177th Street Jamaica, New York, NY11414.
RSTB_370_1673_Cover.indd 5-7
01/06/15 5:25 PM
ISSN 0962-8436 | Volume 370 | Issue 1673 | 19 July 2015
The Society’s strategic priorities emphasise its
commitment to the highest quality science, to
curiosity-driven research, and to the development
and use of science for the benefit of society.
These priorities are:
• Promoting science and its benefits
Phil. Trans. R. Soc. B | Volume 370 | Issue 1673 | 19 July 2015
The Royal Society is a self-governing Fellowship
of many of the world’s most distinguished scientists
drawn from all areas of science, engineering, and
medicine. The Society’s fundamental purpose, as it
has been since its foundation in 1660, is to recognise,
promote, and support excellence in science and to
encourage the development and use of science for
the benefit of humanity.
Cancer across life: Peto’s paradox and the promise of comparative
oncology
Theme issue compiled and edited by Joshua Schiffman, Carlo C. Maley, Leonard Nunney, Michael Hochberg
and Matthew Breen
• Recognising excellence in science
• Providing scientific advice for policy
• Fostering international and global cooperation
• Education and public engagement
For further information on the Royal Society
The Royal Society
6 – 9 Carlton House Terrace
London SW1Y 5AG
T +44 20 7451 2500
W royalsociety.org
For further information on Philosophical Transactions
of the Royal Society B
T +44 20 7451 2602
E philtransb@royalsociety.org
W rstb.royalsocietypublishing.org
Cancer across life: Peto’s paradox and the promise of comparative oncology
• Supporting outstanding science
0962-8436(20150719)370:1673
ISBN: 978-1-78252-144-0
ISSN 0962-8436
The Royal Society Registered Charity No 207043
RSTB_370_1673_Cover.indd 2-4
01/06/15 5:25 PM