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I don't want to grow old.
Selberg, Hanne; Sharp-Johansen, Marie-Louise; Evron, Lotte
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Abstrakt katalog Forskningsdagen SundTek 2015
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2015
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Selberg, H., Sharp-Johansen, M-L., & Evron, L. (2015). I don't want to grow old.In Abstrakt katalog
Forskningsdagen SundTek 2015. (pp. 32)
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Download date: 31. Dec. 2015
Abstract katalog
Forskningsdagen 2015
Det Sundhedsfaglige og Teknologiske Fakultet
Kolofon
Dato & tid
23. september 2015, 8.30-15.30
Sted
Sigurdsgade 26, 2200 København N
ISBN-NR.
978-87-7548-240-5
Arrangør
Prodekan Linda Schumann Scheel
Det Sundhedsfaglige og Teknologiske Fakultet
Professionshøjskolen Metropol
Mikkel Aas Schultz, Projektleder på Forskningsdagen 2015
Idé- og sparringsgruppe
Anders Blædel Gottlieb Hansen, Forsknings- og udviklingskonsulent (Sund-Tek stab)
Hanne Gillett, Uddannelsesleder (Global Nutrition and Health)
Lisbet Madsen, Uddannelsesleder (Institut for Sygepleje)
Lars Holm Rasmussen, Adjunkt (Laborantuddannelsen)
Mette Kreutzfeldt Zebis, Docent (Fysioterapeutuddannelsen)
2
Indhold
FORORD .................................................................................................................................................. 7
PROGRAM ............................................................................................................................................... 8
FORSKNINGS- OG UDVIKLINGSMILJØER .................................................................................................... 9
Personcentrede pleje- og behandlingsforløb ................................................................................................................ 9
Bachelor’s Degree in Global Nutrition and Health - Mad og ernæring til sårbare grupper .......................................... 9
OPLÆGSHOLDERE .................................................................................................................................. 11
Plenum: Promoting food security of low-income women in central Uganda. Vanmala Hiranandani, Ph.D.; lecturer,
Ransom Lekunze Nambuanyi, Ph.D.; Lecturer, Runa Midtvåge, M.Sc., M.Ed., Lecturer; Ecaterina Lazau, Student
intern........................................................................................................................................................................... 11
SPOR 1. SAMFUND OG LÆRING: FRA PROFESSIONSFORSKNING TIL SAMFUNDSMÆSSIG GENNEMSLAGSKRAFT .................. 12
1. Udvikling af sygeplejerskers og sygeplejestuderendes kompetencer til at anvende en klinisk retningslinje i den
kliniske beslutningstagning. Anne-Marie Voss Schrader, Lektor, MPH; Gitte Rom, Lektor, cand.pæd.psyk.; Helle
Vedsegaard, Lektor, cand.mag., Institut for Sygepleje ............................................................................................... 12
2. Helbredsrelateret livskvalitet og tilbagevenden til arbejde efter brystkræft (Ph.D. thesis carried out at Uppsala
University: Health-Related Quality of Life and Return to Work following Breast Cancer). Marie Høyer Lundh,
Adjunkt, MMSc, ph.d., Institut for Sygepleje............................................................................................................... 13
3. Oversættelse og Validering af Canadian Occupational Performance Measure. Anette Enemark Larsen, MScOT,
Lektor, Institut for Fysioterapi og Ergoterapi, Ergoterapeutuddannelsen .................................................................. 14
4. Fra højrisiko til lavrisiko – når stofbrugere benytter stofindtagelsesrum – en undersøgelse af betydningen af
etablering af stofindtagelsesrum (SIR). Nanna Kappel, ph.d., lektor; Jette Tegner, cand.mag, lektor, projektleder;
Eva Toth, cand.scient.san., lektor, Institut for Sygepleje. ........................................................................................... 15
5. Perspektiver for ”reflection-in-action” - Læring fra hverdagens operative indsatser. Mikkel Bøhm, lektor,
cand.scient.soc., ph.d.-studerende, Institut for Teknologi, Katastrofe- og Risikomanageruddannelsen. ................... 16
SPOR 2. TEKNOLOGI OG SUNDHED: FRA MOLEKYLE TIL SAMFUND ............................................................................ 17
6. Leaching of the carcinogen ptaquiloside from bracken ferns (Pteridium sp.) and fate in Danish surface waters.
Lars Holm Rasmussen, Ph.D. (lecturer), Dan Nybro Lindqvist, chem. eng. (senior lecturer), Janni Sandersen, cand.
pharm. (lecturer), Department of Technology, Academy Profession Degree Programme in Chemical and
Biotechnical Science .................................................................................................................................................... 17
7. HER2 antigen ekspressionen blandt cirkulerende tumorceller er heterogen hos brystkræftpatienter. Julie Smith,
postdoc, adjunkt, cand.med.vet, ph.d., Institut for Teknologi, Bioanalytikeruddannelsen ......................................... 18
8. Strukturelle markører for sclerosetræthed målt med magnetisk resonans (MR). Christian Bauer,
Cand.scient.san, ph.d.-studerende .............................................................................................................................. 19
9. Neurobiological substrates for treatment resistance in MTLE. Christina Kjær, lecturer, Department of
Technology lecturer, Bachelor's Degree Programme in Biomedical Laboratory Science ............................................ 20
10. Gll. parotideae efter stråling i hoved-halsområdet. Fysiologiske og funktionelle forandringer detekteret ved
brug af diffusions-vægtet MR scanning (DWI). Maja Bruvo Lazovic, cand.scient., ph.d., Adjunkt, Institut for
Teknologi, Radiografuddannelsen. ............................................................................................................................. 21
.................................................................................................................................................................................... 21
SPOR 3 NUTRITION AND HEALTH IN DIFFERENT CONTEXTS ...................................................................................... 22
11. Implementation of multi-level approaches across EU: hurdles and facilitators. Ann Fenger Benwell, Ph.D.,
Department of Nutrition and Midwifery, Bachelor's Degree in Global Nutrition and Health ..................................... 22
12. Optimized Food Baskets for Romania: Implementation of a Fully Nutritious, Health-Promoting and
Affordable Diet with Linear Programming. Alexandr Parlesak, Ph.D., Dr. habil., Department of Nutrition and
Midwifery, Bachelor's Degree in Global Nutrition and Health .................................................................................... 23
3
13. Hospitable meals in hospitals. Lise Justesen, Senior Lecturer, Ph.D., MSc Food Science, Department of Nutrition
and Midwifery, Bachelor’s Degree Programme in Nutrition and Health .................................................................... 24
14. Fostering Children’s Food Literacy through School Gardens in Denmark. Pernille Malberg Dyg, Lecturer, Ph.D.,
Department of Nutrition and Midwifery, Bachelor's Degree in Global Nutrition and Health ..................................... 25
SPOR 4: SUNDHED, KROP OG TRÆNING ............................................................................................................... 26
15. The effect of near-infrared NIR light and the light-activated antimicrobial agent on wound pathogenic
biofilms; Implication for nonpharmacologic chronic wound treatment. Ghada Said Mohammed Omar, PhD in
Medical Sciences, Department of Physiotherapy and Occupational Therapy............................................................. 26
16. Patientpræference og adherence-rate for træningslokation i træningsbaseret hjerterehabilitering – data fra
Copenheart studierne. Lars Tang, Physiotherapist, Cand scient san. Ph.D.-student, Department of Physiotherapy
and Occupational Therapy .......................................................................................................................................... 27
17. Early physical training and psycho-educational intervention for patients undergoing coronary artery bypass
grafting. The SheppHeartpilot randomised clinical trial. Ida Elisabeth, Højskov, cand.cur., Ph.D.-student,
Department of Nursing ............................................................................................................................................... 28
18. Patient reported shoulder function in patients with subacromial impingement: The role of maximum
isometric force, range of motion and pain. Mikkel Bek Clausen, MS.c., Ph.D.-student, Department of Physiotherapy
and Occupational Therapy, Bachelor's Degree Programme in Physiotherapy ............................................................ 29
POSTERPRÆSENTATIONER – HOLD 1....................................................................................................... 30
INSTITUT FOR SYGEPLEJE ..................................................................................................................................... 30
19. De levede erfaringer ved idiopatisk lungefibrose set fra et patient- og pårørendeperspektiv – et kvalitativt
framework studie. Dorthe Overgaard, docent, seniorforsker, ph.d. Institut for Sygepleje, Ingrid Egerod, Klinisk
professor, sygeplejerske Rigshospitalet Gudrun Kaldan, forskningssygeplejerske Nordsjællands Hospital. .............. 30
21. I don´t want to grow old - Old age simulation in Nursing Education. Hanne Selberg, RN, MEd, Senior Lecturer,
Marie-Louise Sharp Johansen, RN, MSc, Lecturer, Lotte Evron, RN, PhD, Lecturer, Department of Nursing .............. 32
22. Hvorfor fravælger KOL patienter lungerehabilitering? Helle Mathar, sygeplejerske, cand. mag.fil, Pernille
Fastholm, sygeplejerske, cand. scient.san og Niels Sandholm Larsen, sygeplejerske, cand.mag, ph.d. ..................... 33
INSTITUT FOR FYSIOTERAPI OG ERGOTERAPI........................................................................................................... 34
23. Metoder til Optimering og Vurdering af patienter med bipolar sindslidelses funktions evne: MOVE. Lone
Decker, Ergoterapeut, Master i Voksenuddannelse, Lektor ........................................................................................ 34
24. Dysphagia - Single-group pre-post-test study - Effect of rater training on scoring performance and scalespecific expertise amongst occupational therapists participating in a multicentre study. Tina Hansen, Lecturer,
MSc.OT, Ph.d., Occupational therapy Programme ..................................................................................................... 35
25. Force steadiness målt ved elektromyografi og dynamometri hos personer med subacromial impingement
syndrom sammenlignet med skulderraske - et systematisk litteraturstudie. Camilla Keller og Rasmus Tolstrup
Larsen, Fysioterapeuter .............................................................................................................................................. 36
26. A validation study of a protocol that determines the capacity to oxidize fat during exercise in obese adults.
Charlotte Præst, Graduate from Bachelor’s Degree in Physiotherapy, employed at Glostrup Hospital. .................... 37
27. Nexfin device is a reliable measurement of systolic blood pressure increase during heavy resistance exercise.
Kasper Ipsen, BSc i fysioterapi, Bispebjerg Idrætsmedicinsk Forskningsenhed ........................................................... 38
INSTITUT FOR TEKNOLOGI.................................................................................................................................... 39
28. Patienter med atrieflimmer kan nu tilbydes behandling med det nye lægemiddel Rivaroxaban- Ny
analysemetode til bestemmelse af Rivaroxaban lægemiddelkoncentrationen i plasma. Amalie Jesting,
Bioanalytiker ............................................................................................................................................................... 39
29. Retracing Circulating Tumor Cells for Biomarker Characterization after Enumeration. Julie Smith, Post.doc,
Lecturer, Doctor of Veterinary Medicine (DVM), Ph.D. ............................................................................................... 40
30. Predicting preeclampsia and spontaneous preterm delivery by cell free fetal hemoglobin, cell free fetal DNA
and maternal obstetric history. Leif Kofoed Nielsen, Master of Science, Ph.D, Bachelor's Degree Programme in
Biomedical Laboratory Science ................................................................................................................................... 41
4
31. What is it to be sturdy/robust – and can it be trained? Niss Skov Nielsen, Ph.D., Ann Bojsen, M.A., Pablo V.
Holm-Nielsen, Ph.D., Lars Zwisler, M.C., Kurt Pedersen, Professor, Ph.D., Bachelor's Degree Programme in
Emergency and Risk Management ............................................................................................................................. 42
32. Cancerdiagnostik: JAK2 mutationsanalyse ved qPCR metoden. Jan Knudsen cand.scient. (lektor/vejleder),
Amalie Due, Dorte Larsen, Kristina Tornqvist og Nicoline Denning, laborantstuderende ved Professionshøjskolen
Metropol. .................................................................................................................................................................... 43
33. Bracken (Pteridium aquilinum) is the only common fern with ptaquiloside in Denmark. Lars Holm Rasmussen,
PhD, lecturer, Academy Profession Degree Programme in Chemical and Biotechnical Science, Henrik Ærenlund
Pedersen, PhD, associate professor, Natural History Museum of Denmark, University of Copenhagen. ................... 44
34. Using Dynamic Contrast enhanced CT (DCE-CT) to assess the response to treatment of chemotherapy of
colorectal cancer liver metastases. Carsten Lauridsen Ph.D., Bachelor's Degree Programme in Radiography ........ 45
INSTITUT FOR ERNÆRING OG JORDEMODERKUNDSKAB ............................................................................................ 46
35. Barndommens betydning for den tidlige tilknytning - graviditet og moderskab. Vibeke de Lichtenberg, Lektor,
cand.pæd.soc., Jordemoderuddannelsen .................................................................................................................... 46
36. Udviklingen fra underviser til forsker. Studerendes rolle i processen. Line Palle Andersen, lektor og mag.art,
Professionsbacheloruddannelsen i Ernæring og Sundhed .......................................................................................... 47
37. D-vitaminstatus hos danske elitesvømmere. Rikke Larsen, cand.scient. Human Ernæring, Lektor,
Professionsbacheloruddannelsen i Ernæring og Sundhed .......................................................................................... 48
38. Is Adolescent Body Weight Associated With Parental Beliefs About Overweight, Attitudes Towards Food, and
the Home Environment? Alexandr Parlesak, Ph.D., Dr. Habil., Bachelor's Degree in Global Nutrition and Health ... 49
INSTITUT FOR SUNDHEDSFAGLIG OG TEKNOLOGISK EFTER- OG VIDEREUD-DANNELSE ................................................... 50
39. Hvordan kan sundhedsplejersken understøtte handlekompetence, når piger i udskoling møder udfordringer i
forhold til mental sundhed i det postmoderne samfund? Julie Rothaus Voss Rathsach, Sundhedsplejerske,
Sygeplejerske .............................................................................................................................................................. 50
FORSKNINGSSERVICE FRA BIBLIOTEKET METROPOL ................................................................................................. 51
40. Forskningsservice fra Biblioteket Metropol. Anna Møbjerg, informationsspecialist, Bente Larsen,
informationsspecialist, Lene Kaad, informationsspecialist, Trine Azbi, afdelingsleder i biblioteket (kontaktperson). 51
POSTERPRÆSENTATIONER – HOLD 2....................................................................................................... 52
INSTITUT FOR SYGEPLEJE ..................................................................................................................................... 52
41. Involvering og egenomsorg blandt ældre kronisk syge borgere i hjemmesygeplejen. Kathrine H. Pii,
cand.mag., ph.d., Gerd Halskov, cand.cur., ph.d., Institut for sygepleje..................................................................... 52
42. A constipation is casting a shadow over everyday life – a systematic review on elderly people’s experience of
living with constipation. Nina Tvistholm, sygeplejerske, Master of Humanities and Health Studies MHH, Lene
Munch, sygeplejerske, cand.scient.san. ...................................................................................................................... 53
43. Adult Attachment and PTSD or depression symptoms during Rehabilitation of Women newly Diagnosed with
Gynaecological Cancer. Kamila Adellund Holt, Lecturer, cand.scient.san., Ph.D. ...................................................... 54
INSTITUT FOR FYSIOTERAPI OG ERGOTERAPI........................................................................................................... 55
44. Præsentation af ergoterapeut-studerendes projekter fra Sommerskolen 2015. ............................................... 55
45. Tilfredshed med daglige aktiviteter hos asylansøgere i Danmark. Anne-Le Morville, ergoterapeut, ph.d., lektor,
Ergoterapeutuddannelsen .......................................................................................................................................... 56
46. Rapid knee extensions to increase quadriceps muscle activity after total knee arthroplasty: A randomized
cross-over study. Louisa Wilquin, adjunkt, cand.scient., Fysioterapeutuddannelsen................................................. 57
47. Effects of two different intensities of a single bout of acute exercise performed post-learning on
consolidation and retention of motor memory. Marie Kraft, Fysioterapeut, cand.scient. i Humanfysiologi ............ 58
48. Association between maximal hamstring muscle strength and hamstring muscle pre-activity during a
movement associated with non-contact ACL injury. Mette Kreutzfeldt Zebis, M.Sc., Ph.D. ................................... 59
49. Comparison of cardiopulmonary exercise testing (CPET) and oxygen consumption in arm-cranking and
ergometer cycling: a systematic review and meta-analysis. Rasmus Tolstrup Larsen, Physiotherapist .................. 60
INSTITUT FOR TEKNOLOGI.................................................................................................................................... 61
5
50. Fuldgenomsekventering af methicillinresistente Staphylococcus aureus (MRSA) med fokus på mobile
genetiske elementer. Lone Dons, cand.polyt., ph.d., Bioanalytikeruddannelsen ....................................................... 61
Samarbejdsuniversitet ............................................................................................................................................... 61
51. Resistensbestemmelse af gærsvampe – En metodesammenligning af Sensititre YeastOne og Epsilometer test.
Danilo Kalezic & Sandie Nhatien Vu, Bioanalytikere og dimittender fra Bioanalytikeruddannelsen, vejleder Minna
Fyhn Lykke Llado, lektor, Bioanalytikeruddannelsen .................................................................................................. 62
52. Detection/characterization of Tn5801-like mobile genetic elements in tetracycline resistant staphylococci
from pets and humans in Denmark. Lisbeth Elvira de Vries, Lecturer, Ph.D., Academy Profession Degree
Programme in Chemical and Biotechnical Science, Henrik Hasman and Yvonne Agersø, Senior Senior Reseachers,
DTU-FOOD ................................................................................................................................................................... 63
53. Optimering af produktion af koldpresset juice ift. vitamin, mineral- og bakterieindhold. Merete Norsker
Bergsøe, adjunkt, ph.d., Lamia Mohamad Saad, adjunkt, cand. pharm., Pernille Sebnem Salvarli, laborant, tekniker
og Lars Holm Rasmussen, adjunkt, ph.d. Laborant- og Procesteknologuddannelserne ............................................. 64
54. Comparison of STIR and T2 FAT SAT in bone bruise imaging for occult scaphoid fracture. Louise Meincke,
graduate from the Bachelor's Degree Programme in Radiography. ........................................................................... 65
55. Dynamic Contrast Enhanced Computed Tomography: Effects of Non Rigid Motion Correction on image
quality and reproducibility. Kevin Robert Brow og Simon Munch-Jensen, graduates from the Bachelor's Degree
Programme in Radiography. ....................................................................................................................................... 66
INSTITUT FOR ERNÆRING OG JORDEMODERKUNDSKAB ............................................................................................ 67
56. National klinisk retningslinje for behandling af dystoci hos førstegangsfødende (NKR-Dystoci) – udforskning
af baggrund, antagelser og effekt af en evidensbaseret klinisk retningslinje. Lena Mariann Eriksen, Jordemoder,
cand.scient.san., lektor, ph.d.-studerende, Jordemoderuddannelsen ........................................................................ 67
57. Hospital meals experiences and appetite – findings from a Danish study using qualitative visual methods.
Louise H. Nielsen, Bithe Poulsen og Danielle Søndergaard, Bachelors in Nutrition and Health & Lise Justesen, Senior
Lecturer, PhD, MSc Food Science ................................................................................................................................ 68
58. ”Rigtige Måltider”. Udkast til en integral-perspektivistisk evidensmodel. Ulrik Houlind Rasmussen, lektor,
ph.d., Professionsbacheloruddannelsen i Ernæring og Sundhed ................................................................................ 69
59. The Consumption of Enery Drinks Amongst 14-17 Year Old Danish Adolescents: An Examination of the Top
Two Brands Consumed by this Target Group. Maria Juul Nielsen, stud.cand.scient.san.publ, Graduate from
Bachelor's Degree in Global Nutrition and Health ...................................................................................................... 70
INSTITUT FOR SUNDHEDSFAGLIG OG TEKNOLOGISK EFTER- OG VIDEREUDDANNELSE .................................................... 71
60. Hvordan oplever førstegangsforældre at deltage i forældreuddannelse? Og hvilken betydning har
sundhedsplejersken i forhold til at øge forældrenes handlekompetence? Julie Ingvardsen, Sundhedsplejerske,
Sygeplejerske. ............................................................................................................................................................. 71
FORSKNINGSSERVICE FRA BIBLIOTEKET METROPOL ................................................................................................. 72
61. Forskningsservice fra Biblioteket Metropol. Anna Møbjerg, informationsspecialist, Bente Larsen,
informationsspecialist, Lene Kaad, informationsspecialist, Trine Azbi, afdelingsleder i biblioteket (kontaktperson). 72
6
Forord
På denne dag, Forskningsdagen 2015, som afholdes d. 23. september samles de sundhedsfaglige og teknologiske uddannelser på Metropol for tredje år i træk og præsenterer deres forskningsaktiviteter for hinanden
og for eksternt inviterede. Vi har mange forskellige forskningsaktiviteter og dagen udgør en kærkommen lejlighed til at dele gode erfaringer og netværke på tværs af institutter og uddannelser. Der er mange gode eksempler og brugbare erfaringer at lade sig inspirere af.
Siden Professionshøjskolerne kom på Finansloven i 2013, er der sket en kontinuerlig stigning i antallet af
forskning- og udviklingsprojekter (FoU-projekter) på alle uddannelserne i Det Sundhedsfaglige og Teknologiske Fakultets (Sund-Tek) – projekter som involverer et bredt spektrum af mange samarbejdspartnere fra
praksis og fra den øvrige uddannelsessektor.
På dette års forskningsdag er det med glæde, at vi atter præsenterer forskningsprojekter fra ansatte og studerende såvel som dimittender fra alle fakultets uddannelser. Sidste år blev 32 projekter præsenteret – et tal der
er fordoblet i år. Vi har valgt at gruppere oplæggene i fire tematiske spor:
Spor 1: Samfund og Læring: Fra professionsforskning til samfundsmæssig gennemslagskraft,
Spor 2: Teknologi og Sundhed: Fra Molekyle til Samfund,
Spor 3: Nutrition and Health in Different Contexts
Spor 4: Sundhed, Krop og Træning
Sporene repræsenterer forskningsområder, hvor Sund-Teks uddannelser har en særlig ekspertise og bidrager
til at løse presserende samfundsudfordringer.
Vi går nu ind i en ny fase af FoU-indsatsen på Sund-Tek. Der vil i højere grad blive fokuseret på at samle miljøerne og skabe rammerne om en ny FoU-infrastruktur. Vi skal sammen sikre, at gensidig videndeling på
tværs af uddannelserne er en naturlig del af forskning og udvikling på Metropol. Derved kan der opstå synergieffekter og indgås tværfaglige forsknings- og udviklingssamarbejder som kan løse samfundsudfordringer og
skabe ny viden til professionerne. Med Forskningsdagen er der en unik chance for at lære hinanden bedre at
kende og få et endnu bredere kendskab til igangværende forskning på Sund-Tek.
En stor tak til alle bidragsydere til dagen, alle oplægsholdere, medarbejdere i Bygninger, Supportenhed for
Digital Læring, Kommunikation og arbejdsgruppen for forskningsdagen, som alle hjælper til med at gøre denne dag mulig.
Vi glæder os til at byde jer velkommen.
Med venlig hilsen
Linda Schumann Scheel
Prodekan
Det Sundhedsvidenskabelige og
Teknologiske Fakultet
7
'
Program
Overordnet chair for dagen: Anders Blædel Hansen, FoU-konsulent, Sund-Tek Stab
8.30-9.00
Let morgenmad og networking
(kantinens 1.sal og området omkring hovedindgangen)
9.00-9.15
Velkomst og orientering om Forsknings- og Udviklingsaktiviteter på Metropol
v/ Linda Schumann Scheel, Prodekan på Det Sundhedsfaglige og Teknologiske Fakultet
(Auditorium B056)
9.15-9.45
Oplæg i plenum: Promoting Food Security of Low-Income Women in Central
Uganda v/ Lekunze Ransom Nambuanyi; Vanmala Sunder Hiranandani; Runa Midtvåge; Ecaterina
Elena Lazau; Mira Lundsgaard; Bachelor's Degree in Global Nutrition and Health (Auditorium B056)
Chair: Anders Blædel Hansen, FoU-konsulent, Sund-Tek Stab
9.45-10.00
Pause
10.00-11.15
Oplæg spor 1 - Auditorium B056 (Abstract 1,2,3,4,5)
Oplæg spor 2 - Auditorium C060 (Abstract 6,7,8,9,10)
11.15-11.30
Pause
11.30-12.30
Oplæg spor 3 - Auditorium B056 (Abstract 11,12,13,14)
Oplæg spor 4 - Auditorium C060 (Abstract 15,16,17,18)
12.30-13.15
Frokost (kantinens 1.sal og området omkring hovedindgangen)
13.15-13.50
Hold 1 præsenterer posters - Gymnastiksalene E016/E017
13.50-14.25
Hold 2 præsenterer posters - Gymnastiksalene E016/E017
(Sideløbende servering af the, kaffe, frugt og kage).
14.25-14.40
Pause
14.40-15.25
Keynote speech: ”Closing the Gap: the Role of Research in Professional Education”
v/ Philip Moons, Professor in Nursing Science, University of Leuven (Lokale B056)
15.25-15.30
Fælles afrunding af forskningsdagen
v/ Linda Schumann Scheel, Prodekan på Det Sundhedsfaglige og Teknologiske Fakultet
(Lokale B056)
8
Forsknings- og Udviklingsmiljøer
I det Sundhedsfaglige og Teknologiske Fakultet har vi udpeget en række forskningsområder, hvor vi er
stærke og som adresserer de større samfundsudfordringer inden for sundhed, miljø og teknologi, som vi
står overfor.
Hver uddannelse har derfor et forsknings- og udviklingsmiljø (FoU-miljø) med forskningsprojekter, ph.d.forløb, samarbejde med praksispartnere og universiteter m.fl. På Sund-Tek har vi valgt, at forskning og
udvikling skal knyttes tæt til de enkelte uddannelser igennem miljøerne, hvor indsatsen foregår i arbejdsfællesskaber blandt undervisere, der forsker sammen med studerende og praksispartnere.
FoU-miljøerne blev etableret i 2013 og er i løbende udvikling. Nedenfor er kort beskrevet titel og fokus
for miljøerne i dag.
Institut for Sygepleje
Personcentrede pleje- og behandlingsforløb
FoU-miljøet leverer klinisk forskning af høj kvalitet og skaber evidensbaseret viden, der bidrager til brug
af forskningsresultater ind i sygeplejerskeuddannelsen og beriger og udvikler professionspraksis.
Formålet med FoU-miljøet er, at skabe viden om hvordan der kan sikres optimale pleje- og behandlingsforløb, på tværs af sektorer og specialer, med udgangspunkt i den enkelte persons behov og perspektiver. FoU-miljøet er samlet under flg. tre tematikker: Patienter i overgange, Patenter og teknologier, Patienter og pårørende. Tematikkerne samler og fokuserer forskningsaktiviteter og fungerer i samspil og
synergi i ét samlet FoU-miljø på ISY.
Institut for Ernæring og Jordemoderkundskab
Ernærings- og Sundhedsuddannelsen - Mad i centrum
FoU-miljøet arbejder med forskningsbaseret viden om sund kost og ernæring, og om hvordan det bliver
udbredt i praksis. Det er en presserende samfundsmæssig udfordring da antallet af overvægtige er stigende og en relativt stor procentdel af befolkningen lider af diabetes og hjerte-kar sygdomme, der delvist
tilskrives forkert kost.
Bachelor’s Degree in Global Nutrition and Health - Mad og ernæring til sårbare grupper
FoU-miljøet fokuserer på at udvikle bæredygtige interventioner, strækkende sig fra det lokale til det globale niveau, især for grupper, der er særligt udsatte for indtagelse af usund kost eller mangelfuld ernæring. Med afsæt i en tværvidenskabelig tilgang vil uddannelsen udforske hvilke tiltag og interventioner,
der indenfor det kost- og ernæringsmæssige område kan bidrage til at udligne den ulighed i sundhed,
der intensiveres med den stigende globalisering.
Jordemoderuddannelsen - Teknologi og medikalisering i graviditet, fødsel og barsel
FoU-miljøet har som mål at igangsætte projekter og producere viden, der belyser teknologiens muligheder og konsekvenser i moderne graviditet, fødsel og barsel. Uddannelsen beskæftiger sig med den betydning, det har at blive forældre og familie i et moderne teknologiseret samfund, samt betydning og
konsekvenser af den stigende medikalisering der forekommer i graviditet, fødsel og barsel.
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Institut for Fysioterapi og Ergoterapi
Fysioterapeutuddannelsen - Smerte og funktionsevne
Smerte og nedsat funktionsevne skaber højt sygefravær og lavere livskvalitet. Målet for FoU-miljøet er at
kvalificere viden om smerte og funktionsevne. Vi vil udfordre den gængse tankegang om en lineær
sammenhæng mellem smerte og funktionsevne, som afholder mange mennesker fra at leve deres vante
liv. I takt med at fysioterapeuter får flere diagnostiske opgaver inden for det kliniske felt, øges behovet for
viden på området. Vi ønsker at opbygge et forsknings- og udviklingsmiljø der blandt andet bidrager med
ny viden, således at praksis og kommende fysioterapeuter kan løfte denne opgave med afsæt i den nyeste forskning.
Ergoterapeutuddannelsen - Rehabilitering i hverdagsaktivitetsperspektiv
FoU-miljøet har som mål at producere viden om, hvordan vi forbedrer vilkår for deltagelse i hverdagslivet, i hjemmet, på arbejdspladsen og i fritiden. Desuden vil vi på uddannelsen udvikle, teste og validere
undersøgelsesredskaber, og udvikle effektive interventionsformer til rehabilitering i et aktivitetsperspektiv. Der er fokus på undersøgelse af kognitive, mentale og fysiske lidelsers betydning for menneskers
hverdagsaktiviteter og på udvikling af interventionsformer, der kan afhjælpe aktivitetsproblematikker.
Institut for Teknologi
Radiografuddannelsen - Beskrivende radiografi
FoU-miljøet fokuserer på såvel det humanistiske som teknologiske perspektiv inden for det diagnostiske
felt af radiografien. På uddannelsen arbejdes der med at udvikle metoder og kompetenceforløb, som kan
kvalificere radiografers kompetencer inden for billeddiagnostik, og som kan kvalificere andre faggrupper
til at løse opgaver inden for det radiografiske felt.
Bioanalytikeruddannelsen - Laboratoriemedicinsk teknologi – Diagnostik og kvalitet
Forsknings- og udviklingsmiljøet på bioanalytikeruddannelsen er med til at sikre en forskningsbaseret
platform for tidssvarende undervisning samt at højne det faglige niveau for kommende bioanalytikere.
Udgangspunktet for forsknings- og udviklingsmiljøet er den centrale rolle i sygdomsudredning og diagnostik, som bioanalytikerprofessionen i tiltagende grad bidrager med.
Katastrofe- og Risikomanageruddannelsen - Professionel Risikostyring
FoU-miljøet på Katastrofe og Risikomanageruddannelsens har som fokusområde det danske og det
internationale beredskab og et mål om at bidrage til et mere trygt og sikkert samfund, via forebyggende,
forberedende, afhjælpende og genopbyggende aktiviteter. Indsatsområder er udvikling og implementering af operativ risikostyring på virksomheds, sektor-, nationalt og internationalt niveau.
Laborant- og procesteknologuddannelserne - Analyseteknisk specialviden
Udviklingsmiljøet udgør en platform for udvikling af specialviden hos fremtidens laboranter og samarbejder med eksterne partnere og aftagere af dimittender om udvikling af analysetekniske metoder og applikationer. Undervisningen på Laborant- og Procesteknologuddannelserne tager afsæt i den nyeste viden
og skaber et dynamisk fagligt udviklingsmiljø, hvor undervisere og studerende sammen deltager i uddannelsernes forsknings- og udviklingsaktiviteter med udgangspunkt i et dedikeret laboratorium:
FrontLAB-Metropol. Herved får de studerende adgang til de nyeste analysetekniske metoder ligesom de
mødes af undervisere med den nyeste faglige viden.
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Oplægsholdere
Plenum: Promoting food security of low-income women in central Uganda. Vanmala Hiranandani,
Ph.D.; lecturer, Ransom Lekunze Nambuanyi, Ph.D.; Lecturer, Runa Midtvåge, M.Sc., M.Ed., Lecturer; Ecaterina Lazau, Student intern
Partner University/ Collaboration Partner
 Makerere University and Community Health and
Information Network (CHAIN), Uganda
Background, aim and relevance
The purpose of our research project is to investigate the interrelated effects of agricultural practices, land tenure systems, and climate change on women’s food security in the urban and peri-urban areas of central
Uganda.
Methods
With the assistance of local partners, we employed a mixed method approach to collect information in three
municipalities and four parishes. Qualitative information included guided discussion from three community
meetings and eight focus group discussions (FGDs) with key local leaders, as well as semi-structured interviews among 20 female heads of households and 10 key informants. We also collected food security information from 108 households using questionnaires.
All tools were first created in English, pilot-tested in the field and translated into Luganda. Back translation of
the tools was also conducted for the household questionnaires. For the qualitative information, we employed
thematic analysis using NVivo version 10. Descriptive statistics and predictive analysis will be conducted using SPSS for the quantitative data.
(Preliminary) Results
We highlight results from the qualitative data, involving the focus groups, Community meetings, and Key informants. Preliminary results show four of the most common emerging issues as follows:
a) Re-establishment of the traditional notion of a “Household” in Uganda
b) A stronger empowerment of women
c) Revaluation of the role of “Land”
d) Strengthening the Institutional framework
Conclusions
Current findings indicate the need to prioritize policy consideration. Implications include generation of interventions to improve practice and policy on food security for low-income women.
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Spor 1. Samfund og Læring: Fra professionsforskning til samfundsmæssig gennemslagskraft
1. Udvikling af sygeplejerskers og sygeplejestuderendes kompetencer til at anvende
en klinisk retningslinje i den kliniske beslutningstagning. Anne-Marie Voss Schrader,
Lektor, MPH; Gitte Rom, Lektor,
cand.pæd.psyk.; Helle Vedsegaard, Lektor,
cand.mag., Institut for Sygepleje
Partneruniversitet/praksispartner
 Hjertecentret Rigshospitalet, København
 Center for Kliniske Retningslinjer, Ålborg
Universitet
Baggrund, formål og relevans
Implementering af kliniske retningslinjer er en kompleks opgave. Forskningen giver ikke entydige svar på,
hvordan implementeringen lykkes, men organisatoriske, kulturelle og uddannelsesmæssige forhold kan have
indflydelse. Vi har undersøgt, hvordan en anerkendende tilgang bidrager til, at sygeplejersker anvender en
klinisk retningslinje om delirium i den kliniske beslutningstagning.
Metoder
Interventionen foregik ved 18 sygeplejekonferencer med 3-12 deltagende sygeplejersker på en hjerteafdeling.
En klinisk sygeplejespecialist fra afdelingen faciliterede sygeplejekonferencerne med en lektor fra Institut for
Sygepleje som med-facilitator. Efterfølgende gav lektoren sygeplejespecialisten feedback på facilitator-rollen.
Analysen struktureres efter principperne i Grounded Theory, hvor feltnoter analyseres gennem åben, aksial og
selektiv kodning.
Foreløbige resultater
Læring og kompetencer til at implementere den kliniske retningslinje skabes, når det bliver meningsfuldt for
sygeplejerskerne, hvilket viser sig gennem:
 Anvendelse af autentiske patientdata
 Fælleslæring – Læring gennem fællesskab
 Når den patientansvarlige sygeplejerske leder konferencen om egen patient
Konklusioner
Ved anvendelsen af anerkendende tilgang ved sygeplejekonferencer og efterfølgende feedback-seancer blev
det meningsfuldt for sygeplejersker at anvende en klinisk retningslinje som en del af den kliniske beslutningstagning. Desuden dokumenterer journalaudit mindre delirium hos patienterne.
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2. Helbredsrelateret livskvalitet og tilbagevenden til arbejde efter brystkræft (Ph.D. thesis
carried out at Uppsala University: Health-Related Quality of Life and Return to Work following Breast Cancer). Marie Høyer Lundh, Adjunkt, MMSc, ph.d., Institut for Sygepleje.
Collaboration Partner
 Regional Cancer Centre Uppsala Örebro (Sweden)
Background, aim and relevance
An increasing prevalence of breast cancer and continuous developments within breast cancer management
emphasize the importance of improved knowledge about recovery following this disease. The overall aim of
the thesis was to study health-related quality of life (HRQoL) and return to work in the first three years following a breast cancer diagnosis, and to identify clinical and contextual factors associated with these outcomes.
Methods
All four papers in the thesis were part of a population-based cohort study including women registered in the
Breast Cancer Quality Register in central Sweden. A total of 1,573 women were asked to participate in a
questionnaire study with a baseline assessment (response rate 69%) and two follow-ups (response rates 62%
nd
and 54%, respectively). Women participating in the 2 follow-up were individually matched to five breastcancer-free controls. Questionnaire data on HRQoL, socio-demographics and work-related variables were
combined with clinical register, normative and social insurance data.
Results
Following deteriorations within eight months post-diagnosis, HRQoL generally improved during the three years
studied. The majority of women returned to work and sickness absence steadily decreased, but, compared
with the controls, the odds of being on sick leave were increased all three years’ post-diagnosis. Chemotherapy, young age and sick leave/disability pension pre-diagnosis were associated with poorer HRQoL, decreased
working time/job discontinuation and sickness absence post-diagnosis.
Conclusions
Most women with breast cancer gradually recover. In a clinical setting, increased attention should be directed
towards vulnerable subgroups identified in this thesis.
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3. Oversættelse og Validering af Canadian Occupational Performance Measure. Anette Enemark Larsen, MScOT, Lektor, Institut for Fysioterapi og Ergoterapi, Ergoterapeutuddannelsen
Partneruniversitet/ praksispartner
 Ergoterapeutforeningen, Gentofte Hospital
 Hvidovre Hospital
 Bispebjerg Hospital
 Helsingør Rehabilitering og Træningscenter
 Tranehaven
 Sankt Hans Hospital
 DSI Nettet
Baggrund, formål og relevans
I Danmark oplever patienter uadresserede problemer og inadækvat rehabilitering, trods patientinddragelse er
et væsentligt kvalitetsmål i sundhedssektoren. Canadian Occupational Performance Measure (COPM) er et
anerkendt og effektivt redskab til klientinvolvering og anbefales i dansk rehabiliteringspraksis. COPM udkom i
5. udgave i 2014. Tidligere udgaver er oversat til dansk, men disse oversættelser er ikke valideret. Dette projekt undersøger om den danske oversættelse af den 5. udgave af COPM opretholder samme egenskaber som
den oprindelige engelske (face validity).
Metoder
Tolv ergoterapeuter og tre ergoterapeutstuderende har gennemført dansksprogede COPM-interviews med 31
klienter på syv institutioner. Hvert interview er efterfulgt af et valideringsinterview, hvor ergoterapeuterne interviewede de deltagende klienter vedrørende deres oplevelse af redskabet primært med fokus på den sproglige
forståelse. Dernæst gennemførte jeg tilsvarende validerings-interviews med de deltagende ergoterapeuter på
hver arbejdsplads enten som individuelle eller fokusgruppe interviews. Samtlige data analyseres deskriptivt,
hvor indholdet opsummeres og kondenseres.
Foreløbige resultater
Generelt fandt både ergoterapeuter og klienter sproget i den nyoversatte COPM-version passende og anvendeligt med ganske få forslag til korrektioner. Klienterne bekræftede også den forventede positive oplevelse af
at blive hørt.
Konklusioner
Den nyoversatte COPM manual er med enkelte rettelser sprogligt relevant, acceptabel, forståelig og dækkende, og oppebærer således en høj face validity.
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4. Fra højrisiko til lavrisiko – når stofbrugere benytter stofindtagelsesrum – en undersøgelse
af betydningen af etablering af stofindtagelsesrum (SIR). Nanna Kappel, ph.d., lektor; Jette
Tegner, cand.mag, lektor, projektleder; Eva Toth, cand.scient.san., lektor, Institut for Sygepleje.
Samarbejdspartnere og -universitet
Mændenes hjem, København, Århus og Odense Kommune, Kirkens korshær i Odense og Århus,
Lektor Morten Hesse og Birgitte Thylstrup, Center for Rusmiddelforskning, Århus Universitet
Baggrund, formål og relevans
Stofbrugere udgør en højrisiko gruppe med en højere sygelighed, højere dødelighed og lavere gennemsnitslevealder end resten af den danske befolkning. Efter ændringer i narkotikalovgivningen blev det i 2012 muligt
at åbne stofindtagelsesrum, hvor det er muligt at indtage de illegale rusmidler i sikre omgivelser med adgang
til rent værktøj og under overvågning af uddannet personale. Der er indtil videre åbnet stofindtagelsesrum i
Århus, Odense og København i alt 5 stofindtagelsesrum.
Metoder
En mixed method-undersøgelse. Data er indsamlet gennem deltagerobservation, kvalitative interviews og en
spørgeskemaundersøgelse. Der er foretaget 250 timers observation i SIR. Der er foretaget interviews med 42
stofbrugere og 25 personale, og der er gennemført en spørgeskemaundersøgelse med 154 stofbrugere.
(Foreløbige) resultater
Stofbrugere er overordnet godt tilfredse med at komme i SIR. De oplever at blive mødt med anerkendelse af
personalet. Det er trygt og sikkert at indtage rusmidlerne i stofindtagelsesrummene, der er under overvågning
af uddannet personale. Ud over at forebygge og håndtere overdosis og forgiftningssituationer arbejder personalet på at etablere relationer med udsatte stofbrugere, hvilket er forudsætningen for at kunne hjælpe og vejlede storbrugerne i forbindelse med hygiejne og injektionsteknik. Relationsarbejdet foregår konstant i et ofte
meget hektisk miljø. Desuden arbejdes der med brobygning dels til sundhedsklinikker, dels til sundhedssektoren og til misbrugsbehandling og det sociale system
Konklusioner
Meget udsatte og marginaliserede stofbrugere benytter SIR. Stofindtag transformeres fra højrisiko situationer,
hvor rusmidlerne indtages under uhygiejniske og stressfyldte forhold, til lavrisikosituationer, hvor rusmidlerne
indtages i sikre omgivelser under overvågning af kvalificeret personale. Stofbrugerne får hjælp til at komme
videre i systemet, når de er motiverede for det. Personalet arbejder relationelt med henblik på at yde forebyggende og behandlende indsatser i forhold til at undgå overdosisdødsfald, og SIR bidrager til at nedbringe
antallet af overdosis dødsfald i Danmark
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5. Perspektiver for ”reflection-in-action” - Læring fra hverdagens operative indsatser. Mikkel Bøhm, lektor, cand.scient.soc.,
ph.d.-studerende, Institut for Teknologi, Katastrofe- og Risikomanageruddannelsen.
Samarbejdspartnere og -universitet
Ph.d.-projektet er finansieret af Professionshøjskolen Metropol og Roskilde
Universitet. Hovedvejleder Peter Hagedorn-Rasmussen. Medvejleder professor Kurt Petersen, LUCRAM, LUND. Feltstudier i Danmark gennemføres
ved Københavns Brandvæsen samt ved ”Den Præhospitale Virksomhed i
Region H (akutlægerne). Feltstudier i Norge gennemføres ved ”Rogaland
Politidistrikt” og ”Rogaland Brann og Redning IKS”. Gennemføres i samarbejde med professor Ove Njå, SEROS, UIS.
Baggrund, formål og relevans
Indsatsledere fra Redningsberedskabet indgår året rundt i håndteringen af akutte hændelser. Denne håndtering er knyttet til konstruktionen og forhandlingen af den sociale realitet på skadestedet – forstået som ”hvad
står vi overfor og hvad bør vi gøre”? Disse meningsskabelsesprocesser forløber hurtigt og ofte tavst, hvilket
gør det vanskeligt at arbejde med læring fra disse situerede hændelser. Ofte ender man med at med retrospektivt at diskutere, hvad gjorde vi? Uden dog at adressere, hvorfor vi skabte den mening, som vi gjorde, og
derved bliver det vanskeligt eksplicit at tilgå og transformere den operative praksis. Ved at undersøge de situationer, hvor indsatslederen som privilegeret meningsskaber bliver udfordret, er det muligt at diskutere de
muligheder og begrænsninger, som indsatslederen har, for at reflektere i nuet.
Metoder
For at kunne undersøge konstruktionen og forhandlingen af den sociale realitet benytter projektet data, der er
indsamlet ved hjælp af hjelmkamera, der er fastgjort til indsatslederens hjelm (brandvæsenet) eller skulder
(politiet). Kameraet gør det muligt at fastfryse meningsskabelsesprocesserne, mens de bliver skabt. Gennem
en dialogisk analysestrategi, hvor indsatslederen aktivt deltager, optøs og udkondenseres begivenheder, der
understøtter såvel som blokerer for konstruktionen af den sociale realitet.
(Foreløbige) resultater
De empiriske fund viser, at konstruktionen og forhandlingerne af den sociale realitet er meget sårbar. Dette
bliver tydeligt, hvis der optræder noget atypisk på en operativ hændelse, der udfordrer den mentale simulation
og den indledende situationsbedømmelse. I disse situationer er der behov for at eksplicitere de kognitive,
emotionelle og fysiologiske processer, som den enkelte indsatsleder oplever, for derigennem at invitere til en
fælles konstruktion af et ledelsesrum, der gør det muligt for indsatslederen at agere proaktivt.
Konklusioner
Projektets undersøgelser viser, at der er behov for metodiske tilgange, der kan facilitere sprogspil på skadestedet, som derigennem kan virke som en katalysator på konstruktionen og forhandlingen af den sociale realitet.
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Spor 2. Teknologi og Sundhed: Fra Molekyle til Samfund
6. Leaching of the carcinogen ptaquiloside from bracken
ferns (Pteridium sp.) and fate in Danish surface waters.
Lars Holm Rasmussen, Ph.D. (lecturer), Dan Nybro Lindqvist,
chem. eng. (senior lecturer), Janni Sandersen, cand. pharm.
(lecturer), Department of Technology, Academy Profession
Degree Programme in Chemical and Biotechnical Science
Partner University/Collaboration Partner
 Department of Plant and Environmental Sciences, University of
Copenhagen (UCPH).
Background, aim and relevance
Ptaquiloside (PTA) is a carcinogen present in bracken ferns. PTA is readily leached from fronds by rain and
was in 2014 detected in shallow groundwater and surface waters in Danish Bracken areas. At present, the
leaching pattern is unknown.
PTA is quite mobile and rather stable in the terrestrial environment. PTA undergoes acid as well as alkaline
hydrolysis to form a number of carcinogenic metabolites with unknown fate. Further insight into the biogeochemistry of PTA and metabolites is needed to assess the impact of the compound on human health.
The aim of the project is to develop analytical methods for quantification of PTA and metabolites in bracken
and surface water to determine the environmental load and fate.
Methods
The project comprises three action areas:
1. Development of analytical methods: Set-up of analytical capacity at METROPOL in collaboration with
UCPH (LC-MS/MS and LC-MS).
2. Identification of factors influencing frond leaching: Frond dip concentrations and the effects on the PTA
content in fronds after biogenic disturbance (field-study, LC-MS).
3. Stability of PTA in surface water: The degradation pattern was studied and metabolites identified in
natural waters (laboratory study, LC-MS/LC-MS/MS).
(Preliminary) Results
PTA was purified from bracken by using an improved extraction method (recovery: approx. 10%, purity: approx. 80%). Analytical standards were made from this product and used for method development/validation
and degradation studies. Quantification of PTA and metabolite formation was done by internal/external standardization (loganin as IS).Formation of metabolites will be studied under natural conditions and by reacting
PTA with different organic and inorganic acids and bases (Autumn 2015). Leaching will be studied under natural conditions at Ravnsholt Forest (August 2015).
Conclusions
Two new MS-based methods were developed and validated for identification and quantification of PTA and
metabolites in plant and water samples.
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7. HER2 antigen ekspressionen blandt cirkulerende tumorceller er heterogen hos brystkræftpatienter. Julie Smith, postdoc, adjunkt, cand.med.vet, ph.d., Institut for Teknologi, Bioanalytikeruddannelsen
Partner University/ Collaboration Partner
 CytoTrack ApS, Lyngby, Denmark
 CTC Center of Excellence, Department of Clinical Biochemistry, Nordsjællands
Hospital, University of Copenhagen, Denmark
Background, aim and relevance
Treatment of metastatic breast cancer is guided by characterization of the primary tumor. Potentially, a blood
sample can personalize therapy further by characterization of the human epidermal growth factor receptor 2
(HER2) expression profile on circulating tumor cells (CTCs). This study describes a novel method that determines HER2 surface antigen expression on individual CTCs in peripheral blood.
Methods
A HER2 immunofluorescence staining method was developed by using cell lines with known HER2 expression spiked in donor blood. With the CytoTrack system, the tumor cells were detected and enumerated and
subsequently stained with HER2 antibody in a PBS solution. The HER2 expression profiles were then evaluated by retracing individual tumor cells. Additionally, clinical blood samples from 10 metastatic breast cancer
patients were analyzed.
(Preliminary) Results
The tumor cells spiked in donor blood showed the expected HER2 expression profiles after CTC enumeration
followed by HER2 characterization. Moreover, CTCs were detected in six of ten patient specimens. Two patients showed significant HER2 expression heterogeneity, i.e. CTCs stained positive for HER2 in 12 of 14 and
in 7 of 22 respectively. In the remaining 4 patients, either all or none CTCs stained positive for HER2.
Conclusions
A novel method for CTC enumeration and HER2 characterization of individual CTCs is tested. HER2 heterogeneity was observed among CTCs in patients with breast cancer.
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8. Strukturelle markører for sclerosetræthed målt med magnetisk resonans (MR)1. Christian
Bauer, Cand.scient.san, ph.d.-studerende
Partner University/ Collaboration Partner
 Danish Research Centre for Magnetic Resonance,
Copenhagen University Hospital, Hvidovre
 Danish Multiple Sclerosis Centre, Department of Neurology,
Copenhagen University Hospital Rigshospitalet
Copenhagen
 Department of Neurology, Copenhagen University Hospital
Bispebjerg, Copenhagen
Background, aim and relevance
Multiple Sclerosis (MS) is a chronic and disabling disease that diffusively attacks the central nervous system.
Fatigue is one of the most common and most disabling symptoms in MS. The aim of this Magnetic Resonance
Imaging (MRI) study is to demonstrate structural substrates explaining motor fatigue. Novel sophisticated Diffusion Weighted Imaging (DWI) models will be applied to test the hypothesis that fatigue in MS is associated
with impaired structural cortico-cortical and cotrico-spinal connectivity.
Methods
50 mildly disabled MS patients with relapsing remitting MS will be recruited from the Danish Multiple Sclerosis
Centre, Rigshospitalet, and via the Danish Multiple Sclerosis Association. Patients are split in two age- and
sex-matched groups: patients reporting fatigue (n=25) and patients without fatigue (n=25). 25 healthy ageand sex-matched individuals are recruited as controls. All participants undergo a MS standard battery of test,
questionnaires and multimodal whole-brain MRI, including T1- and T2-weighted imaging, Fluid Attenuated
Inversion Recovery (FLAIR). In addition, we will perform DWI and Magnetic Transfer Ratio Imaging (MTR) for
microstructural evaluation of the brain. New analysis models will be applied to the DWI data to extract detailed
information about intra- and extracellular tissue compartments as well as fibre dispersion in specific white
matter (WM) tracts.
Hypotheses:
In MS patients with fatigue, we expect alterations in regional microstructure and structural connectivity in the
premotor frontal lobe which will correlate with fatigue severity.
(Preliminary) Results
Data collection will soon be finished. So far 41 patients (f/m) 29:12 and 22 healthy controls (f/m) 15:7 have
been included. The mean age was 36 years in both groups. Data analysis has started in terms of preprocessing, but no statistical analyses have been performed yet.
Conclusions
This study is work in progress – generating a unique multimodal MRI data set in MS. Data acquisition has
been challenging but feasible.
1
Note that the presentation is in Danish.
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9. Neurobiological substrates for treatment resistance in MTLE. Christina Kjær, lecturer, Department of Technology lecturer, Bachelor's Degree Programme in Biomedical Laboratory Science
Partner University/ Collaboration Partner
 University of Copenhagen
 Copenhagen University Hospital Rigshospitalet
Background, aim and relevance
Epilepsy is the most common serious chronic neurological condition associated with major comorbidities including mood disorders and cognitive dysfunction. In Europe alone, epilepsy affects six million people of all
ages (about 50.000 in Denmark), and the economic costs attributable to epilepsy exceed ~€14 billion per
year. Despite medical advances in treatment, approximately 30% of patients continue to have seizures. It is
currently not possible to predict which patients respond to which medication. The biology underlying drug resistance is still poorly understood and there are no biomarkers to predict treatment response
Methods
In the present project, we want to use transcriptome profiling combined with in vitro drug exposure to identify
gene expression differences in the brains of medial temporal lobe epilepsy (MTLE) patients that are either
responders or non-responders versus non-epileptic patients who undergo temporal lobectomy due to brain
tumors.
Our hypothesis is that epilepsy alters the molecular regulation in brain tissue, such that epileptic foci react
differently to medical treatment compared with healthy tissue.
We will test this hypothesis by specific research questions:
1. Does the epileptic focus (hippocampus) of patients with MTLE have a different gene expression profile compared with “healthy” cortical tissue from the same patients?
2. Does the relative effect of antiepileptic drugs (AEDs) in hippocampus and cortex from MTLE patients
predict clinical effects of these AEDs in the patients?
3. Do patients with intractable MTLE, patients with treatable MTLE, and non-epileptic patients have a different gene expression profiles in the epileptic focus?
.
(Preliminary) Results
The present project will enable identification of new molecular candidates for drug response and potentially
help to guide existing strategies for treatment of epilepsy.
Conclusions
Prediction, or even early identification of intractability, could ensure better clinical management of patients by
combined drug therapy and surgery to achieve remission.
20
10. Gll. parotideae efter stråling i hoved-halsområdet. Fysiologiske og funktionelle forandringer detekteret ved brug af diffusions-vægtet MR scanning (DWI). Maja Bruvo Lazovic,
cand.scient., ph.d., Adjunkt, Institut for Teknologi, Radiografuddannelsen.
Samarbejdspartner
 Herlev-Gentofte Hospital, Radiologisk- og Stråleterapeutisk afdeling
 Tandlægeskolen, Københavns Universitet.
Baggrund, formål og relevans
Ørespytkirtler (Gll. parotideae), ligesom de øvrige spytkirtler, er meget sensitive over for strålingen og derfor
er nedsat spytsekretion den hyppigste senfølge som opstår efter strålebehandling af hoved-halsområdet. Hvis
spytkirtlerne er inkluderet i strålefeltet ved behandlingen af hoved-halskræft, kan det medføre varig skade på
spytkirtlerne. Spyttets sammensætning ændres også som følge af stråleskader på spytkirtelvævet i form af
lavere pH, nedsat bufferkapacitet, ændret proteinkoncentration og øget viskositet. Strålebehandling-induceret
mundtørhed kan yderligere føre til orale infektioner, dental caries, tale-, smage-, synke- og spisebesvær, som
alle er bivirkninger som forringer patienternes livskvalitet. Imidlertid kan der indtræde en delvis restituering af
spytkirtelfunktion inden for to år efter strålebehandlingen, og der vil ofte forekomme en reduktion i graden af
mundtørhed.
Metoder
Ørespytkirtler hos patienter med diagnosticeret hoved-halskræft undersøges før og efter stråleterapi, for at
visualisere de bivirkninger som stråling har på spytkirtelvæv. Undersøgelsen indebærer en MR scanning med
en diffusionsvægtet sekvens, måling af spytsekretionshastighed, spytopsamling, samt undersøgelsen af
mundtørhedsgraden. Efterfølgende vil spyttets sammensætning blive undersøgt. Alle undersøgelser gentages
igen et år efter afsluttet stråleterapi.
(Foreløbige) resultater
Det forventes, at resultaterne af disse undersøgelser til sammen kan bruges til at vurdere strålebehandlings
relaterede skader på ørespytkirtler, deres fysiologiske forandringer, samt om mundtørheden hos patienten vil
være varig.
Konklusioner
Muligheden for korrekt diagnosticering af mundtørhed ved brug af disse non-invasive metoder vil gavne patienterne, da det vil give mulighed for et mere individuelt behandlingsvalg og på sigt også en bedre livskvalitet.
21
Spor 3 Nutrition and Health in Different Contexts
11. Implementation of multi-level approaches across EU:
hurdles and facilitators. Ann Fenger Benwell, Ph.D., Department of Nutrition and Midwifery, Bachelor's Degree in
Global Nutrition and Health
Partner University/ Collaboration Partner
 VU University Medical Center (The Netherlands) Coordinating
Centre
 The University of Oxford (United Kingdom)
Background, aim and relevance
In order to address obesity in Europe, efforts target individual and environmental-level factors that promote
healthy lifestyle behaviours. In order to evaluate the effectiveness of interventions that include contextual factors, we evaluated barriers and facilitators of these interventions in the UK, the Netherlands, and Denmark.
Methods
We conducted 22 in-depth interviews about dynamics and perceptions of planning and implementing interventions from October 2013 and January 2014.
(Preliminary) Results
Twenty-eight pre-identified themes were confirmed, while six new themes were identified. Respondents identified proactive project management, collaboration and bottom-up approaches as facilitators. Hurdles were lack
of resources, target group participation and shared visions and ownership. Using the reach, effectiveness,
adoption, implementation and maintenance (RE-AIM) evaluative framework, these identified hurdles resulted
in interventions that were less successful in promoting healthy lifestyle behaviors.
Conclusions
Projects commonly shared a lack of needs assessment, project fatigue, and in terms of inequality, not reaching women and men most in need. Implications of this study indicate the need for rigorous evaluation of multilevel based interventions, especially in light of addressing inequality.
22
12. Optimized Food Baskets for Romania: Implementation of a Fully Nutritious, HealthPromoting and Affordable Diet with Linear Programming. Alexandr Parlesak, Ph.D., Dr. habil.,
Department of Nutrition and Midwifery, Bachelor's Degree in Global Nutrition and Health
Partner University/ Collaboration Partner
 WHO Europe, João Breda, PhD,
 WHO, Country Office Romania, Victor Olsavszky, MD
Background, aim and relevance
High cost of low-energy food that is rich in micronutrients is considered to be the main obstacle to achieve a
health-promoting diet in Romanian families with limited financial resources.
Methods
Using linear programming, we developed a cost-optimized method how to achieve best food baskets that
cover all recommended intakes of nutrients and contribute to a nutrition that helps to prevent obesity and the
metabolic syndrome. Price-controlling nutrients are identified, the cost for the “health” property of the food
baskets was calculated and a price-optimized approach to diversify these baskets was applied.
(Preliminary) Results
The most affordable version of a fully nutritious, health-promoting food basket for a Romanian family of four (2
adults, 2 children) costs 19.65 Lei (~€ 4.46) (spring 2014). Of this amount, 6.3% account for its healthpromoting properties. This price is primarily dictated by vitamin D, calcium, potassium and iron. As compared
to the current consumption in Romania, the diversified, cost-optimized baskets contain significantly more
roots, tubers, and fish but considerably less meat, fat & oils, and sugar.
Conclusions
Only linear programming can guarantee both adequate nutrition and cost-efficient diversification of healthpromoting food baskets. Keeping the health-promoting properties constant, increased consumption of roots,
tubers, and fish and a reduction in meat intake can contribute considerably to reduce cost for a healthy nutrition in Romania.
23
13. Hospitable meals in hospitals. Lise Justesen, Senior Lecturer, Ph.D., MSc Food Science, Department of Nutrition and Midwifery, Bachelor’s Degree Programme in Nutrition and Health
Partner University/ Collaboration Partner
 Planning and Development, MENU, Research group for Public
Health Nutrition and Meal sciences, Aalborg University.
Background, aim and relevance
Hospital food has been criticized for being of poor quality, and 30-40 percent of hospitalized patients are considered to be at risk of undernutrition. Existing scientific research related to hospital meals are based on
knowledge gained from verbal or written methods whereby food, people and the environment are considered
static agents. This research project explores hospital meals and hospital meal experiences through other epistemological positions, such as visual methods and by considering hospital meal experiences as dynamically
and socially-material constructed in combination with a hospitality approach. The aim is to reconsider hospital
meals and to bring new value into future hospital meals.
Methods
This research project is based on an ethnographic study of hospital meals served in gynecological and cardiological departments at Holbæk Hospital in 2012. The empirical data is based on three visual methods, six
months of observations, and 22 semi-structured interviews.
(Preliminary) Results
Hospital meals are perceived as social and imaginary and thus food becomes representative of an invisible
host. Hospital meals can be described as pop-up restaurants in which the hospital rooms physically and sensorial transforms into a meal-place where patients become guests. These transformation-processes are negotiated co-creatively by giving artefacts new meanings and by giving the patients the opportunity to shift between host and guest roles. The ability to co-create hospitable meals is challenged by efficiency rationales as
well as non-articulated culturally learned meal practices. Hospitable meals can be co-created in shifting atmospheres and evocative events.
Conclusions
This research project provides added value to future hospital meal experiences. The ability to balance between structured clinical meal practices and the ability to co-create (un)predictable meal events, can give the
patients an opportunity co-create hospitable meals. Furthermore it can become a platform for considering
levels of appetite and undernutrition as well.
24
14. Fostering Children’s Food Literacy through School Gardens in Denmark. Pernille Malberg
Dyg, Lecturer, Ph.D., Department of Nutrition and Midwifery, Bachelor's Degree in Global Nutrition
and Health
Partner University/ Collaboration Partner
 Institut for Uddannelse og Pædagogik, Århus
Universitet
Background, aim and relevance
We investigated pedagogy and the outdoor setting in school gardens and effects on child learning about food
and taste.
Methods
Qualitative study of five school gardens using observation, interviews with teachers and educators and focus
group discussions with children after program completion.
(Preliminary) Results
Preliminary findings show that children gain an understanding and motivation related to the seed-to-table process, food diversity, taste for new foods and cooking skills.
Conclusions
Children benefit through increased motivation, connectedness to nature and a desire to obtain knowledge
regarding the origin of their food, seeing themselves as part of a bigger food system. Implications may involve
political support through national educational and health promotion strategies.
25
SPOR 4: Sundhed, Krop og Træning
15. The effect of near-infrared NIR light and the light-activated antimicrobial agent on wound
pathogenic biofilms; Implication for nonpharmacologic chronic wound treatment. Ghada
Said Mohammed Omar, PhD in Medical Sciences, Department of Physiotherapy and Occupational
Therapy
Partner University/ Collaboration Partner
 University College London
 Cairo University
Background, aim and relevance
Chronic infected wounds represent a significant cause of morbidity in developed countries and are estimated
to affect 1-2 % of the population. In Denmark, 2–3% of the health care budget is used on wound treatment
and the socioeconomic problem will keep growing worldwide due to the increase of lifestyle diseases, as diabetes, obesity, and cardiovascular diseases. The presence of bacterial biofilms is considered an important
factor responsible for wounds chronicity. Therefore, this study investigates the efficacy of near-infrared (NIR)
laser in vitro, in disrupting wound pathogenic biofilms.
Methods
Biofilms of Staphylococcus aureus and Pseudomonas aeruginosa were grown in a 96-well microtiter plate for
18-22 h. The study included 4 arms: (a) control; (b) 200 µg/mL Indocyanin green (ICG) kept in the dark, (c)
NIR laser alone; (d) NIR laser combined with 200 µg/mL. ICG. The biofilms were exposed to different light
2
doses from the 808 nm NIR laser at a fluence rate of 0.3 W/cm . Crystal violate assay and viable count were
used to detect the effect.
(Preliminary) Results
2
A light dose of 90 J/cm killed approximately 99.9% of P. aeruginosa bacterial cells encased in biofilms, while
a combination of both light and dye resulted in a 99.3% kill. Exposure of Staph. aureus biofilms to ICG in
combination with NIR laser light or to the NIR light alone resulted in 99.9% and 99.7% reductions in the number of viable bacteria, respectively.
Conclusions
NIR laser alone was superior to the combination of ICG and NIR light in killing P. aeruginosa biofilms. However the combination of NIR with ICG was more effective in disrupting Staph. aureus biofilms. Thus NIR light
laser may be a promising nonpharmacologic treatment method for disrupting biofilms present in chronic
wounds.
26
16. Patientpræference og adherence-rate for træningslokation i træningsbaseret hjerterehabilitering – data fra Copenheart studierne. Lars Tang, Physiotherapist, Cand scient san. Ph.D.student, Department of Physiotherapy and Occupational Therapy
Partner University/ Collaboration Partner
 Projekt CopenHeart, Hjertecenteret, Rigshospitalet.
 CopenRehab, Afdelingen for Social Medicin,Instituttet for Folke
sundhedsvidenskab, Københavns Universitet.
Background, aim and relevance
Attendance to exercise-based cardiac rehabilitation (CR) is associated with beneficial health effects. CR delivery service has the past years changed from traditional CR to more self-initiated exercise programs. Therefore, it is important to clarify patients’ preference for mode of delivery and the attendance rates between traditional CR and self-initiated programs.
We hypothesize that a higher number of patients would prefer a center-based training approach but attendance rates would be similar between delivery modes. The study is still in progress.
Methods
The study combines rehabilitation data from two randomized controlled trials. Patients that underwent radiofrequency ablation (RFA) for atrial fibrillation or heart valve surgery (VR) and participating in exercise intervention in the two trials were included. The rehabilitation intervention included a 12 weeks outpatient programme
with three sessions per week. Patients could choose between centre-based-training at 29 collaborating training locations or self-initiated training in accordance with their preferences. Patient characteristics were obtained at baseline (e.g. marital- and employment status). Attendance to each exercise session was assessed
with individual training diaries and/or heart rate monitors. Comparative analysis and logistic regression were
performed.
(Preliminary) Results
Mode of delivery was equally preferred between the 158 patients (p=0.223). Fifty-five percent (95% CL 45%63%) preferred center-based training against 44% (95% CL 37%-53%) who perform self-initiated training. We
found no differences in attendance rate between mode of delivery when adjusting for sex, age and patient
type (Odds ratio=1.53 (95% CI: 0.75-3.09)).
Conclusions
Nearly half of patients undergoing RFA or VR participating in CR prefer self-initiated training, but delivery of
exercise-based CR based on patient’s preference provides similar attendance rate across settings. Findings
provide insights in the provision of exercise-based CR but must be confirmed in a large-scale study.
27
17. Early physical training and psycho-educational intervention for patients undergoing coronary artery bypass grafting. The SheppHeartpilot randomised clinical trial. Ida Elisabeth,
Højskov, cand.cur., Ph.D.-student, Department of Nursing
Partner University/ Collaboration Partner
 Metropolitan University College, Copenhagen Trial Unit, Rigshospitalet, Univer
sity of Copenhagen
Background, aim and relevance
Patients undergoing coronary artery bypass graft surgery often experience a range of problems and symptoms as immobility, pain and insufficient sleep. Results from trials investigating testing in-hospital physical
exercise or psychological intervention have been promising. However, no randomized clinical trials have tested a comprehensive rehabilitation programme consisting both of physical exercise plus psychoeducation in
the early rehabilitation phase.
Methods
60 patients admitted for coronary artery bypass graft were randomized 1:1:1:1 to: 1) physical exercise plus
usual care, or 2) psycho-educational intervention plus usual care, or 3) physical exercise and psychoeducational plus usual care, or 4) usual care alone during a 4 week period after surgery.
(Preliminary) Results
The acceptability of trial participation was 67% during the three month recruitment period. In the physical exercise groups, patients complied with 59% of the total expected training sessions during hospitalization. Nine
patients (30%) complied with >75% and nine patients (30%) complied with 50% of the planned exercise sessions. Eleven patients (42%) participated in ≥75% of the four consultations and six patients (23%) participated
in 50% of the psycho-educational programme.
Conclusions
Comprehensive phase one rehabilitation combining physical exercise and psycho-education in coronary artery
bypass graft patients shows reasonably high inclusion, feasibility, safety and a sufficient inclusion rate, but
moderate compliance with most elements.
28
18. Patient reported shoulder function in patients with subacromial impingement: The role of
maximum isometric force, range of motion and pain2. Mikkel Bek Clausen, MS.c., Ph.D.-student,
Department of Physiotherapy and Occupational Therapy, Bachelor's Degree Programme in Physiotherapy
Partner University/ Collaboration Partner
 Copenhagen University Hospital, Hvidovre
 Amager Hospital
Background, aim and relevance
Subacromial impingement (SIS) is related to impairments in maximum isometric force and range of motion
(ROM). The extent of these impairments, and how force and pain influences patient-reported shoulderfunction, is unknown. The purpose was: First, to quantify impairments in maximum isometric force in shoulder
abduction (ABD-force), external-rotation (ER-force), protraction (PRO-force), horizontal-extension (HE-force),
active abduction ROM (AB-ROM) and passive internal-rotation ROM (IR-ROM) in SIS-patients; secondly, to
investigate the influence of these impairments on patient-reported shoulder-function in SIS-patients.
Methods
From 169 consecutive SIS-patients, 156 (92%) completed the Shoulder Pain And Disability Index (SPADI).
Impairments in isometric force and ROM of the affected shoulder compared to unaffected shoulder were investigated in patients with unilateral shoulder pain. A priori, SPADI function score (SPADI-F), was chosen as
the dependent variable in a multiple regression, with ABD-force, ER-force and ABD-ROM, pain during each
test (Numeric Rating Scale (NRS): 0-10) and pain during last week (NRS: 0-10) as independent variables. All
analyses were adjusted for Age, Gender, Sick leave, Medication use, Kinesiophobia and if the affected shoulder was the dominant.
(Preliminary) Results
SIS-patients with unilateral pain had significant impairments in ABD-ROM (-28%), IR-ROM (-11%), ER-force (33%), ABD-force (-29%) and HE-force (-18%) (p<0.001), and also in PRO-force (-8%, p<0.05). Only pain during tests and during last week were found to influence SPADI-F score (total variance explained=23.4%,
p<0.001).
Conclusions
SIS-patients had substantial impairments in maximum force and ROM, but only pain variables influenced the
SPADI-F score. As SPADI-F score does not reflect the substantial strength and ROM impairments observed
in SIS-patients, supplemental assessment of these impairments seems important.
2
Note that the presentation is in Danish
29
Posterpræsentationer – Hold 1
Institut for Sygepleje
19. De levede erfaringer ved idiopatisk lungefibrose set fra et patient- og pårørendeperspektiv – et kvalitativt framework studie. Dorthe Overgaard, docent, seniorforsker, ph.d. Institut for
Sygepleje, Ingrid Egerod, Klinisk professor, sygeplejerske Rigshospitalet Gudrun Kaldan, forskningssygeplejerske Nordsjællands Hospital.
Samarbejdspartnere
 Nordsjællands Hospital, Lunge- og Infektionsmedicinsk
afdeling, Hillerød. (Lungemedicinere Kristoffer Marsaa,
Thyge Lynghøj Nielsen og projektsygeplejerske Rikke
Overgaard)
 Gentofte Hospital; Lungemedicinsk afdeling, (Lungemediciner Saher Burhan Shaker, projektsygeplejersker
Ruth Fuursted og Yvonne Mackeprang)
 Rigshospitalet, København,TraumeCentret, HovedOrto
Centret, (Klinisk professor Ingrid Egerod)
Baggrund, formål og relevans
Idiopatisk lungefibrose (IPF) er en progressiv lungesygdom, der har en dårlig prognose med en overlevelse på
2-4 år. Der eksisterer lidt kvalitativ forskning, der beskriver, hvorledes det er at leve med IPF, og hvilken betydning pårørende har.
Metoder
Undersøgelsen er en kvalitativ, eksplorativ undersøgelse med 25 semistrukturerede dybdeinterview.
Der benyttes Framework analysemodel, og der anvendes NVivo softwareprogram til organisering af data.
Deskriptiv statistik vil blive anvendt til at præsentere demografiske data.
(Foreløbige) resultater
Tyve ud af 25 var ægtepar, og resten var udvalgte pårørende.
Vi fremanalyserede seks temaer: 1) Information 2) dyssynkroni 3) konstant overvågenhed 4) følelsesmæssig
ambivalens 5) gradvis rolleskift og 6) mestringsstrategier.
Vi analyserede på tre niveauer: a) patienten – b) pårørende og c) interaktionen mellem a) og b).
Konklusioner
Fundene kan bidrage til at målrette pleje funderet på IPF-patienternes og de pårørendes behov.
Anbefalinger i forhold til hvilke forbedringer, der kan imødekomme patienters- og pårørendes udækkede behov.
30
20. Stratification of patients with type 2 diabetes in a specialised outpatient clinic – a crosssectional study. Lene Munch. cand.scient.san., Ph.D.-student at Copenhagen University
a,b
a
a
b
a,c
a
Lene Munch , Anne B. Arreskov , Michael Sperling , Dorthe Overgaard , Filip K. Knop , Tina Vilsbøll , Mia
chael E. Røder
Partner University/ Collaboration Partner
a
 Center for Diabetes Research, Gentofte Hospital, University of
Copenhagen, Hellerup, Denmark,

b
Institute of Nursing, University College Metropol, Copenhagen,
Denmark,
 NNF Center for Basic Metabolic Research and Department of
Biomedical Sciences, Faculty of Health and Medical Sciences,
University of Copenhagen, Copenhagen, Denmark
c
Background, aim and relevance
To target optimised medical care, the Danish guidelines for diabetes recommend stratification of patients with
type 2 diabetes into three levels according to risk and complexity of treatment: level 1 (uncomplicated), level 2
(intermediate risk), level 3 (high risk). The aim was to describe the type 2 diabetes population, measure the
compliance of the endocrinologists’ to perform risk stratification, and investigate the level of concordance between stratification performed by the endocrinologists and objective assessments.
Methods
A cross-sectional study with data from electronic sources. The risk stratification model contained seven criteria: HbA1c, blood pressure, microvascular and macrovascular complications. Objective assessments were
compared with the endocrinologists’ assessments.
(Preliminary) Results
Of 245 newly referred patients, 209 (85%) were stratified by endocrinologists to level 1 (16%), level 2 (55%)
and level 3 (29%). By objective assessments, 4% were stratified to level 1, 51% to level 2 and 45% to level 3.
Of 419 long-term follow-up patients, 380 (91%) were stratified by endocrinologists to level 1 (5%), level 2
(57%) and level 3 (38%). By objective assessments, 3% were stratified to level 1, 58% to level 2 and 39% to
level 3. The concordance rate between endocrinologists’ and objective assessments was 63% among newly
referred (kappa 0.39; fair agreement) and 67% for long-term follow-up (kappa 0.45; moderate agreement).
There were no significant differences in marginal distribution within long-term follow-up patients. Among newly
referred, the endocrinologists stratified less patients at level 3 compared to objective assessments (p<0.0001).
Conclusions
Type 2 diabetes patients, newly referred to or allocated for long-term follow-up in the out-patient clinic, were
mainly intermediate and high-risk, complicated patients, in accordance with national guidelines. Compliance of
stratification performance by the endocrinologists was high, but level of concordance between endocrinologists’ and objective assessments was not strong.
31
21. I don´t want to grow old - Old age simulation in Nursing Education. Hanne Selberg, RN,
MEd, Senior Lecturer, Marie-Louise Sharp Johansen, RN, MSc, Lecturer, Lotte Evron, RN, PhD,
Lecturer, Department of Nursing
Background, aim and relevance
A previous simulation-based education project showed that by acting as the patient in simulation activities,
attention was brought to the student`s own body and resulted in a sensatory expression, tacit knowledge and
enhanced theory-practice integration.
Methods
Through participant observation, we explored students' understanding of the aging process and how they
learn wearing an old age simulation suit. The students engaged in everyday life activities such as eating,
climbing stairs, getting in and out of bed. The suit enables students to experience the inconveniences of musculoskeletal, visual and auditory changes.
Five two-hours' workshops were conducted with 60 students in total. The workshops consisted of an initial
briefing, scenario performance, debriefing and final evaluation.
(Preliminary) Results
Themes from analysis:
 Concerns of growing old
 Bodily experiences of movement reduction and in the different senses
 Simulation as an eye-opener to new understandings of old age
 Cognitive and bodily experiences of the time perspective
 Bodily-kinesthetic learning
Conclusions
Our results indicate that old age simulation enhanced learning as a result of combined physical and cognitive
activities receiving information from all the senses and emotional involvement. The study suggests bodily activity in simulation enhance learning.
32
22. Hvorfor fravælger KOL patienter lungerehabilitering? Helle Mathar, sygeplejerske, cand.
mag.fil, Pernille Fastholm, sygeplejerske, cand. scient.san og Niels Sandholm Larsen, sygeplejerske, cand.mag, ph.d.
Samarbejdsuniversitet
 Hvidovre Lungemedicinsk afdeling v. Gerd Martinez og
Peter Lange
Baggrund, formål og relevans
KOL er et globalt sundhedsproblem, og det forudses, at KOL i 2020 bliver den tredjehyppigste dødsårsag.
Sygdommen er blandt de hyppigste dødsårsager i Danmark og 10 % af de samlede sygehus - og sygesikringsudgifter går til behandling af KOL-patienter. KOL-rehabilitering reducerer åndenød og træthed blandt
KOL-patienter, øger livskvalitet og evne til at mestre sygdommen og medfører færre hospitalsdage. Alligevel
afviser mellem 30 og 50 % af KOL-patienter helt at tage imod tilbud om KOL rehabilitering. Forskningsspørgsmålet er: Hvorfor fravælger KOL-patienter lungerehabilitering?
Metoder
Interview med 20 patienter, der har fravalgt rehabiliteringstilbud. (færdiggøres juni 2015). Transskription af
interview foretages af en studerende og valideres af interviewer. Dataanalyse metoden er induktiv indholdsanalyse/content analysis inspireret af Elo & Kyngäs og Graneheim.
(Foreløbige) resultater
De foreløbige resultater bekræfter delvist anden forskning på området. Lungerehabilitering fravælges pga.:
andre prioriteringer, manglende information om tilbuddet, manglende forståelse af rehabiliteringskonceptet, og
oplevelse af manglende behov for rehabilitering. Nyt er det at patienterne i undersøgelsen beskriver KOL som
underordnet andre konkurrerende lidelser og derfor ikke er interesseret i KOL rehabilitering.
Konklusioner
Der foreligger ikke konklusioner på nuværende tidspunkt.
33
Institut for Fysioterapi og Ergoterapi
23. Metoder til Optimering og Vurdering af patienter med bipolar sindslidelses funktions evne: MOVE. Lone Decker, Ergoterapeut, Master i Voksenuddannelse, Lektor
Samarbejdsuniversitet/praksispartner
 Kompetencecenter for Affektive lidelser, Psykiatrisk Center
København. Region Hovedstadens Psykiatri
 Parker Instituttet, Købehavns Universitetshospital
Bispebjerg & Frederiksberg
Baggrund, formål og relevans
Prævalensen af bipolar sindslidelse i Danmark er ca. 1 % svarende til ca. 40.000 patienter. På trods af såvel
medicinsk som psykologisk behandling oplever op til 50 % af patienter med bipolar sindslidelse, selv når de er
velbehandlede, ofte vedvarende og invaliderende funktionsevnenedsættelse i form af kognitive vanskeligheder samt vanskeligheder i forhold til at udføre aktiviteter. Disse gener vanskeliggør patienternes uddannelse,
fastholdelse på arbejdsmarkedet og sociale relationer. Det er ikke undersøgt, hvorledes de kognitive vanskeligheder påvirker den del af funktionsevnen på aktivitets- og deltagelsesniveau, som omhandler evnen til at
udføre Activities of Daily Living (ADL). Derfor er formålet med aktuelle studie at beskrive ADL-evnen hos patienter med bipolar sindslidelse samt sammenhængen mellem kognitive vanskeligheder og ADL-evne.
Metoder
Der inkluderes 40 patienter med bipolar sindslidelse i remission, som har subjektive klager over kognitive vanskeligheder. Kognitive funktioner undersøges med et bredt neuropsykologisk testbatteri, der måler styringsfunktioner, koncentration, psykomotorisk tempo og hukommelse: The Screen for Cognitive Impairment in
Psychiatry (SCIP), Trail Making Test A og B, Danish Adult Reading Test (DART). Deltagernes ADL evne udredes med Assesment of Motor and Process Skills (AMPS).
(Foreløbige) resultater
Hypotesen er, at patienter med bipolar sindslidelse har en lavere ADL-evne end raske jævnaldrende, samt at
mål for kognitive funktioner vil være moderat associeret til ADL-evne.
Konklusioner
Der foreligger ikke konklusioner på nuværende tidspunkt.
34
24. Dysphagia - Single-group pre-post-test study - Effect of rater training on scoring performance and scale-specific expertise amongst occupational therapists participating in a multicentre study. Tina Hansen, Lecturer, MSc.OT, Ph.d., Occupational therapy Programme
Partner University/ Collaboration Partner
 Region Herning Hospital
 Region Holstebro Hospital
 Region Silkeborg Hospital
 Dept. Of Rehabilitation - OUH, Odense University Hospital
 City of Århus, Care homes and rehabilitation
 Rehabilitation section, City of Hillerød
 Rehabilitation section, City of Copenhagen
Background, aim and relevance
Dysphagia is being identified as a growing symptom among clients with different diagnosis. Valid assessments are required. To enhance the quality of the data collected in a multi-centered validation study of the
Danish version of the McGill Ingestive Skills Assessment (MISA), a rater training program was developed.
Methods
A 2-days rater training program, qualified 81 occupational therapists (OTs) in observing and scoring dysphagic
clients’ mealtime performance, according to the criteria for 36 items in the MISA. Training effects were evaluated pre- to post-training using percentage exact agreement (PA) of scored MISA items of a case-vignette and
a Likert scale self-report of scale-specific expertise.
(Preliminary) Results
PA increased significantly from pre- to post-training (Z = -4.404, p <0 .001), although items for which the casevignette reflected deficient mealtime performance appeared most difficult to score. The OTs scale-specific
expertise improved significantly.
Conclusions
Rater training improved OTs scoring performance in using the Danish MISA as well as their perceived scalespecific expertise. Further studies addressing different training approaches and durations are warranted.
35
25. Force steadiness målt ved elektromyografi og dynamometri hos personer med subacromial impingement syndrom sammenlignet med skulderraske - et systematisk litteraturstudie.
Camilla Keller og Rasmus Tolstrup Larsen, Fysioterapeuter
Baggrund, formål og relevans
Størstedelen af alle skuldersmerter skyldes subacromial
impingement syndrom (SIS). Tidligere studier har vist, at
smerte kan føre til ændringer af α- og γ-neuron aktiviteten, proprioceptionen og i det neuromuskulære aktiveringsmønster, der alle influerer på motorisk kontrol. Det
anbefales, at rehabiliteringen af personer med SIS på
trods af lav til moderat evidens bør indeholde motorisk
kontrol. På baggrund af dette bør det vurderes, hvorvidt
force steadiness som et mål for den motoriske kontrol er
afficeret hos personer med SIS sammenlignet med skulderraske.
Metoder
Der blev foretaget en systematisk søgning i databaserne PubMed, Embase, CINAHL og PEDro, samt en efterfølgende systematisk artikelvurdering vha. Sundhedsstyrelsens cheklister.
(Foreløbige) resultater
Fire artikler blev inkluderet. Ingen af artiklerne angav en signifikant forskel ved force steadiness målt ved dynamometri og elektromyografi. De inkluderede artiklers metodiske kvalitet blev vurderet lav.
Konklusioner
Kvaliteten af den nuværende evidens er lav, og sammenligningsgrundlaget lille. Det kan dermed ikke konkluderes, hvorvidt der kan registreres en forskel under force steadiness hos personer med SIS sammenlignet
skulderraske.
36
26. A validation study of a protocol that determines the capacity to oxidize fat during exercise in obese adults. Charlotte Præst, Graduate from Bachelor’s Degree in Physiotherapy, employed at Glostrup Hospital.
Partner University/ Collaboration Partner
 Center of Healthy Aging, Dept., Biomedical Sciences,
University of Copenhagen
Background, aim and relevance
Achten et al. introduced a cycle ergometer test that determines the maximal fat oxidation capacity (MFO) and
validated this in lean, well-trained men by indirect calorimetry. A test to obese, untrained individuals has not
been validated. Therefore, the aim of this study was to validate a protocol that determines MFO and the relative intensity at which it occurs (Fatmax) in obese individuals.
Methods
Six subjects (3W & 3M; BMI: 36±4) performed two tests; a graded exercise test(GE-test) starting at 30 watt for
6 min and increasing with 20(W)/25(M) watt/3 min. The test stopped when the respiratory exchange ratio
(RER) reached 1.0. On a separate day three 10-min bouts(CE-test) at 35, 50 and 65% of VO2max(maximal
oxygen uptake) were performed. A Fatmax-curve was constructed from the GE-test and fat oxidation
rates(g/min) were compared at the CE-test intensities using an Interclass Correlation Coefficient (ICC) and a
Bland-Altman plot with 95% Limits of Agreement(LoA).
(Preliminary) Results
Fatmax was reached at 44±2% of VO2max (range: 38-50). The agreement between protocols was limited. The
relative agreement was low (ICC: XXX) and the absolute agreement, illustrated with a Bland-Altman plot with
95 % LoA, indicated a large variation (LoA: XXXg/min).
Conclusions
Based on the 6 subjects included in this study, the protocol using 3-min stages to determine MFO and Fatmax
in obese individuals showed limited validity. More subjects are needed to make a definitive conclusion of the
validity.
37
27. Nexfin device is a reliable measurement of systolic blood pressure increase during heavy
resistance exercise. Kasper Ipsen, BSc i fysioterapi, Bispebjerg Idrætsmedicinsk Forskningsenhed
Partner University/ Collaboration Partner
 Center of Healthy Aging, Dept., Biomedical Sciences, University of
Copenhagen
Background, aim and relevance
Resistance training has become an integrated part of rehabilitation programs because it effectively improves
several conditions that are related to co-morbidities in heart patients. However, resistance training has also
been associated with acute rise in blood pressure levels. The safety concern has been discussed especially
among heart patient. The purpose of this study was to investigate the use of a non-invasive blood pressure
device Nexfin, measuring systolic blood pressure adaptations during heavy resistance exercise. Our hypothesis is that Nexfin device is a reliable non-invasive method investigating acute blood pressure adaptation performing resistance exercise.
Methods
The present study is a test-retest study, where inter-day reliability of the Nexfin device was investigated. Ten
healthy male subjects performed 3x8 repetitions in a leg press machine on two different days, and blood pressure was measured simultaneously. The linear correlation between the two test days was evaluated by the
Pearson correlation coefficient.
(Preliminary) Results
The Pearson correlation coefficient was high – i.e. r =0.88. No systematic bias were found between the two
test days (P < 0.05, paired t-test). Typical error in percentage was 3.5%.
Conclusions
In conclusion, the finding of this study suggests that Nexfin is a reliable measurement of systolic blood pressure during heavy resistance exercise.
38
Institut for Teknologi
28. Patienter med atrieflimmer kan nu tilbydes behandling med det nye lægemiddel
Rivaroxaban- Ny analysemetode til bestemmelse af Rivaroxaban lægemiddelkoncentrationen
i plasma. Amalie Jesting, Bioanalytiker
Samarbejdsuniversitet
Klinisk Biokemisk Afdeling på Rigshospitalet
Baggrund, formål og relevans
Nye direkte orale antikoagulerende lægemidler (Rivaroxaban) kan erstatte behandlingen med traditionelle
vitamin K antagonister. I modsætning til vitamin K antagonister er der ikke behov for fast monitorering ved
behandling med Rivaroxaban. Der er dog alligevel et behov for at kunne måle lægemiddelkoncentrationen i
plasma. To analysemetoder har vist potentiale til koncentrationsbestemmelse af lægemidlet. Metoderne er
henholdsvis kromogent assay til måling af direkte faktor Xa hæmmere (BiophenDiXaI)og massespektrometri
kombineret med væskekromatografi (LC-MS/MS).
Metoder
Vi har optimeret en analysemetode på LC-MS/MS til bestemmelse af Rivaroxabankoncentrationen i Na-citrat
plasma. Analyse-metoden blev kalibreret op til 1000µg/L, hvorefter analysemetodens korrekthed og præcision
blev bestemt. Til sidst blev der gennemført en metodesammenligning mellem LC-MS/MS metoden og Biophen
DiXaI analysemetoden ved at sammenholde resultater fra 84 prøver fra patienter i behandling med Rivaroxaban.
(Foreløbige) resultater
For LC-MS/MS metoden var den interserielle korrekthed imellem 91,6% og 118,1% (acceptgrænser er 80120%); den interserielle præcision (CV%) var imellem 4,7% og 7,1%. Metodesammenligningenen ved lineær
2
regression imellem LC-MS/MS og Biophen DiXaI gav en R værdi på 0,9831 for koncentrationer under 500
µg/L. Bland Altman plot viste god overensstemmelse for koncentrationer under 500 µg/L med en gennemsnitsdifference på +6,41 µg/L. For koncentrationer over 500 µg/L viste metodesammenligningen dårlig overensstemmelse.
Konklusioner
Det er muligt at måle Rivaroxaban koncentrationen i plasma ved brug af LC-MS/MS. Sammenhængen mellem
de to anvendte analysemetoder er dog dårlig for koncentrationer i det toksiske område (<500 μg/L).
39
29. Retracing Circulating Tumor Cells for Biomarker Characterization after Enumeration. Julie
Smith, Post.doc, Lecturer, Doctor of Veterinary Medicine (DVM), Ph.D.
Partner University/ Collaboration Partner
 CytoTrack ApS, Lyngby, Denmark
 CTC Center of Excellence, Department of Clinical Biochemistry, Nordsjællands Hospital, University of Copenhagen, Denmark
Background, aim and relevance
Retracing, isolation and characterization of individual circulating tumor cells (CTCs) may contribute to personalized metastatic cancer therapy. This is relevant when obtaining a metastasis biopsy is complicated or impossible.
Methods
A novel disc format was used to map and retrace individual CTCs from patients with breast cancer and nucleated cells from blood from healthy blood donors using the CytoTrack platform. For proof of the retracing concept, HER-2 characterization of CTC by immunofluorescence was tested.
(Preliminary) Results
CTCs were detected and enumerated in 3 of 4 blood samples and the locations of each individual CTCs were
mapped on the discs. Nucleated cells were retraced on 7 discs with 96.6%±8.5% recovery on 5 fields of views
on each disc. Shifting of cells for retracing was measured to 4-29 µm. In a blood sample from a patient with
HER2 positive tumor, CTC enumeration and mapping was followed by HER2 characterization and retracing to
demonstrate downstream immunofluorescence analysis of CTC in a breast cancer patient.
Conclusions
Mapping and retracing of CTCs enables downstream analysis on individual CTCs for existing and future cancer genotypic and phenotypic biomarkers.
40
30. Predicting preeclampsia and spontaneous preterm delivery by cell free fetal hemoglobin,
cell free fetal DNA and maternal obstetric history. Leif Kofoed Nielsen, Master of Science, Ph.D,
Bachelor's Degree Programme in Biomedical Laboratory Science
Partner University/ Collaboration Partner
 Department of Obstetrics, Juliane Marie Centret,
4001, Rigshospitalet, Copenhagen University
Hospital (Tanja Roien Jakobsen, Ann Tabor)
 Department of Obstetrics, Hvidovre Hospital,
Copenhagen University Hospital (Tanja Roien
Jakobsen)
 Clinical Research Centre, Copenhagen
University Hospital, Hvidovre, Denmark (Steen
Ladelund)
 Department of Clinical Immunology, Bloodbank,
2034, Rigshospitalet, Copenhagen University
Hospital (Klaus Rieneck, Frederik Banch
Clausen)
 Department of Clinical Biochemistry,
Rigshospitalet, Copenhagen University Hospital
(Jens Bundgaard)
Background, aim and relevance
The objective was to evaluate whether two different plasma markers, cell free fetal DNA (cffDNA) and cell free
fetal hemoglobin (HbF) are predictive of preeclampsia and spontaneous preterm delivery in asymptomatic
pregnant women when tested at two routinely implemented antenatal visits, the double test at gestational age
(GA) 8+0 to 13+6 weeks and the antenatal RHD screening at 25 weeks.
Methods
This was a retrospective case-control study including 700 singleton pregnant women with chromosomally
normal fetuses. Only women who had the antenatal RHD screening performed in GA 23-28 weeks were included in the final study period. The blood samples were analyzed for HbF, Hb and pregnancy associated
plasma protein A (PAPP-A) in weeks 8+0 to 13+6 and will be analyzed for HbF, total hemoglobin (Hb) and
cffDNA in weeks 23-28.
(Preliminary) Results
A total of 29 women developed preeclampsia and 50 women delivered spontaneously preterm. In the first
trimester, we did not find a difference in biochemical markers between cases and controls for neither
preeclampsia nor spontaneous preterm delivery. Concerning the second trimester samples analysis is still
ongoing.
Conclusions
The present methods for detection of HbF and total Hb is not able to discriminate between women who develop PE, and those who do not in the first trimester.
41
31. What is it to be sturdy/robust – and can it be trained? Niss Skov Nielsen, Ph.D., Ann Bojsen,
M.A., Pablo V. Holm-Nielsen, Ph.D., Lars Zwisler, M.C., Kurt Pedersen, Professor, Ph.D., Bachelor's Degree Programme in Emergency and Risk Management
Partner University/ Collaboration Partner
 University of Lund, Sweden
Background, aim and relevance
There is a higher incidence of morbidity and of psychological symptoms – ie. PTSD and depression - in military and in emergency/rescue professional business compared to the Danish adult population (1). It is a demand from military and from emergency/rescue professional business that their personnel must be "sturdy/robust". Studies of a synonymous term: "Hardiness" have shown, that a high score on this scale can be
related to a lower incidence of psychiatric symptoms among deployed in stressful environments (2). A similar
scale: SOC (Sense of Coherence) has also proved suitable to assess people's resilience to stressors (3).
Purpose: This paper intends to give a first insight into the concept of being "sturdy/robust"; to develop and
test a Danish model of how to measure sturdiness/robustness; to test the scale's ability to identify people in
emergency situations who have high risk of developing psychological illness.
Methods
The concept of being sturdy will be discussed with stakeholders in the aim to develop important factors of
what it means to be “sturdy/robust”. This will be used as input for a Danish screening tool. The Scale will be
tested among employees from disaster related professions. Scores will be compared with development of
symptoms and different types of illnesses, in order to identify scores that can be used as limits for deselecting
persons that are likely to develop diseases and symptoms
(Preliminary) Results
Expected results:
 A robustness/sturdy questionnaire
 A scale that can be used to prevent that vulnerable persons are being ordered to tasks that exceed their
capacity
 A possible age/gender specific scale
Conclusions
Can the questionnaire show long-term effects from stressful workloads and from violent experiences?
Can the questionnaire be used to point out/prevent vulnerable employees from stressful exposure?
Is it possible to learn how to become sturdy/robust?
42
32. Cancerdiagnostik: JAK2 mutationsanalyse ved qPCR metoden. Jan Knudsen cand.scient.
(lektor/vejleder), Amalie Due, Dorte Larsen, Kristina Tornqvist og Nicoline Denning, laborantstuderende ved Professionshøjskolen Metropol.
Samarbejdsuniversitet
 Roskilde Sygehus
Baggrund, formål og relevans
Real-Time kvantitativ PCR (qPCR-metoden) benyttes i dette projekt til mutationsanalyse af patientprøver (oprenset genomisk DNA) fra Roskilde Sygehus.
Patienterne lider af blodkræftsygdommen Polycythemia Vera – en sygdom, som forårsages af en punktmutation i JAK2 genet, og som fører til en overproduktion af blodceller fra knoglemarven.
Sygdommen kan behandles med stoffet interferon α (immunterapi), men ikke kureres.
Formålet med projektet er at undersøge ændringer i mutationsfrekvenser som følge af behandling med interferon α.
Konkret gøres dette ved at måle frekvensen af sygdoms-allellen (JAK2 V617F) i forhold til vildtype allellen i
patientmaterialet. Endvidere måles forskellen i smeltepunktstemperatur mellem vildtype DNA og mutant DNA.
Metoder
I projektet anvendes Real-Time kvantitativ PCR med efterfølgende smeltepunktsanalyse af DNA. Den benyttede PCR metode valideres mht. detektionsgrænse og effektivitet, samt de benyttede primeres sensitivitet.
Resultater
I 2. delforsøg er patientmaterialet undersøgt med såvel vildtype primere som mutant primere. Der sås tydelige
forskelle i allelfrekvenser mellem de forskellige patientprøver.En forskel i smeltepunktstemperatur mellem
vildtype- og mutant DNA kunne ikke konstateres ved det benyttede udstyr. Detektionsgrænsen for PCRmetoden blev bestemt til 1pg/µL, med en effektivitet af amplifikationen på 95%. Vildtype primernes sensitivitet
blev beregnet til 1:265, og mutant primernes sensitivitet til 1:46.000.
Konklusioner
Det er lykkedes at påvise forskelle i den relative frekvens af mutant DNA i de analyserede prøver. Dette giver
mulighed for at monitorere et evt. fald i mutationsfrekvensen i patientmateriale som resultat af en behandling
med interferon α.
43
33. Bracken (Pteridium aquilinum) is the only common fern with ptaquiloside in Denmark.
Lars Holm Rasmussen, PhD, lecturer, Academy Profession Degree Programme in Chemical and
Biotechnical Science, Henrik Ærenlund Pedersen, PhD, associate professor, Natural History Museum of Denmark, University of Copenhagen.
Partner University/Collaboration Partner
 Natural History Museum of Denmark
 University of Copenhagen
Background, aim and relevance
Ptaquiloside (PTA) is carcinogen present in several ferns all-round the World. PTA courses bladder cancer
among bovines, blindness among sheep and acute bleedings among calves. The interaction between PTA
and animals are most studied in the context of Bracken ferns (Pteridium sp.) as these ferns are very common
and contains high concentrations of PTA. The International Agency on Research on Cancer (IARC) has classified Bracken in Group 2B (possibly carcinogenic to humans). However, Bracken and PTA is placed at the
urgency list of agents and exposures to be considered in the future.
PTA can be absorbed by Humans through food (fern/contaminated milk/meat), air (spores) or drinking water
(fern leachates). This route has been demonstrated for Bracken ferns and a few other Asian ferns (e.g. Pteris
sp., Dryopteris sp. and Onychium sp.). Until now, only Pteridium aquilinum has been investigated for content
of PTA in Denmark. The aim of the project was to make a risk-assessment of common Danish ferns in order
to elucidate PTA presence in the environment.
Methods
Denmark has 29 fern species. 8 are very rare/protected species, hence not covered in the screening. Samples were collected August-September 2014, dried at ambient temperature in a plant-press (acid-free paper).
Reference samples kept at UCPH. The use of plant collections (herbariums) for PTA/PtB screening was tested by including 5 specimens aged 10-50yrs.
Samples were milled and PTA extracted by deionized water. The content of PTA was measured as PTAequivalents at a HPLC-DAD system after conversion of PTA to PtB. PtB was measured directly in the extracts.
Results
Full-spectra were obtained from 190 to 400nm of all extracts. Spectral patterns were compared to external
standards of pure PtB. PTA – and PtB – was only identified in Bracken fern from Denmark. The result is surprising as some of the families investigated have been reported containing PTA. PTA and PtB was found in all
herbarium specimens.
Conclusions
Bracken is the only common fern qualifying for further risk-assessment with respect to PTA contamination of
the environment. Old plant collections can be used for qualitative studies of PTA/PtB.
44
34. Using Dynamic Contrast enhanced CT (DCE-CT) to assess the response to treatment of
chemotherapy of colorectal cancer liver metastases. Carsten Lauridsen Ph.D., Bachelor's Degree Programme in Radiography
Partner University/ Collaboration Partner
Department of Diagnostic Radiology, Rigshospitalet,
Copenhagen University Hospital
Background, aim and relevance
Chemotherapy is the treatment of choice in patients with metastatic spread from colorectal cancer. Antiangiogenetic drugs as Bevacizumab have an angiogenesis-inhibiting effect. These drugs act by disrupting the vascular network of pathological tissues and may not change tumor size as a consequence of its action. Therefore, response evaluation based on lesion size changes may need to be integrated with quantitative evaluation of tissue vascularization. Since DCE-CT provides qualitative and quantitative information on perfusion
values in normal and metastatic liver tissue, DCE-CT has potential to monitor therapy-induced perfusion
changes in various types of lesions. This study assessed the usefulness of DCE-CT to evaluate the effects of
chemotherapy combined with antiangiogenetic treatment on liver metastases in patients with advanced colorectal cancer.
Methods
Image analysis was performed at a dedicated workstation encompassing measurement of the arterial and
portal tissue perfusion (AF, PF) and Perfusion Index (PI = AF/(AF+PF)%) of the metastases. The perfusion
values were calculated using dual input, maximum slope model. The presentation reveals preliminary data
from four patients, being the first of a planned larger study including 40 patients. The patients underwent three
examinations, which were performed at pre-treatment baseline, 14 days after the start of the treatment, and
together with the normal routine CT examination (app. 6 weeks after treatment onset).
(Preliminary) Results
So far we have analysed DCE-CT data of four patients.. One patient showed a mean decrease of 30% (perfusion index (PI)) between the first and second examination. This patient was a partial responder. The other
three patients showed similar PI values for the first and second examination. One of these patients was a
partial responder and two had stable disease according to the RECIST criteria.
Conclusions
No conclusions can be drawn as the study is work in progress. We expect that the study will clarify the added
value for DCE-CT in treatment monitoring of metastatic colorectal cancer.
45
Institut for Ernæring og Jordemoderkundskab
35. Barndommens betydning for den tidlige tilknytning - graviditet og moderskab. Vibeke de
Lichtenberg, Lektor, cand.pæd.soc., Jordemoderuddannelsen
Samarbejdsuniversitet/praksispartner
 Forskningsenheden Kvinders og Børns Sundhed, Juliane Marie Centret,
Rigshospitalet
Baggrund, formål og relevans
Forskning inden for tilknytningsteorien finder, at det i vid udstrækning er vores tidlige relationelle erfaringer,
som former, hvordan vi forholder os til os selv og til andre. Begrebet tilknytning danner grundlag for at forstå
de helt særlige psykologiske processer, der finder sted mellem barn og forældre. Menneskets tidlige relationer
former individets oplevelse af sig selv og er dermed afgørende for, hvorvidt den enkelte udvikler sig til et trygt
og selvstændigt menneske, der tør komme andre mennesker nær, eller modsat oplever en fundamental
utryghed i tilværelsen. Tilknytningsteorien betragtes i dag som den vigtigste psykologiske teori til dybdegående undersøgelse af relationen mellem spædbarn og forældre, af relationens betydning for barnets senere
udvikling og af voksnes mentale strategier for regulering af tilknytningsrelaterede følelser. Teorien tilsiger således en sammenhæng mellem tilknytningsmønstret hos den primære omsorgsperson og barnets mentale
repræsentationer af tilknytning. Det er denne sammenhæng, som projektet tager afsæt i.
Metoder
Projektet forløber over to faser; først et kvalitativt studie af gravide kvinders tilknytningsmønster og relationen
til eget barn og herefter – baseret på disse resultater – udvikling af praksisredskab til brug i jordemoderfaglig
praksis.
Fase 1:
 Interviewundersøgelse af 30 gravide ud fra omfattende modificeret spørgeguide baseret på AAI og WMCI.
 Interviewundersøgelse af 30 mor/barn par 6-10 måneder efter fødslen (jf. George & Solo-mon 2008) ud fra
PDI og modificeret WMCI, her med fokus på den interviewdel, der omhandler fødslen.
Informanter rekrutteres i regi af TUBA.
Fase 2:
Udvikling af en kondenseret/modificeret spørgeguide på baggrund af resultaterne fra fase 1. Der ses på sammenhænge mellem AAI, WMCI og PDI, samtidig med at interviewene analyseres med henblik på at identificere de interviewspørgsmål, der giver mest information og den største mætningsgrad. (jf. Slade et al 2012; Killén 2010).
(Foreløbige) resultater og konklusioner
Foreligger endnu ikke
46
36. Udviklingen fra underviser til forsker. Studerendes rolle i processen. Line Palle Andersen,
lektor og mag.art, Professionsbacheloruddannelsen i Ernæring og Sundhed
Baggrund, formål og relevans
Undersøgelsen belyser de første erfaringer med at inkludere studerende i forskningsprojekter på SUND-TEK.
I slutningen af 2013 var der gennemført 8 projekter på hhv. Ernæring og sundhedsuddannelsen, Radiografuddannelsen, Sygeplejerskeuddannelsen og Ergoterapeutuddannelsen. Undersøgelsen viste blandt andet varierende opfattelser af, hvad der er forskning, og hvad forskning indebærer.
Undersøgelsen blev indledt som et studie i talentudvikling, hvor målet var at undersøge, efter hvilke kriterier
studerende var udvalgt, og hvad man gjorde for at udvikle dem fagligt.
Metoder
Diskursanalyse af 8 kvalitative interviews af undervisere/ph.d.'ere fra Sund-Tek, der har lavet forskning eller
forskningslignende projekter
Resultater
Hurtigt viste det sig, at de fleste studerende som blev inddraget i forsknings- og udviklingsprojekter selv havde
taget initiativ til at henvende sig til projektets medarbejdere med forespørgsel om at få mulighed for at medvirke. Forskerne oplevede ikke at de studerende som henvendte sig udmærkede sig fagligt.
De involverede forskere udtrykte imidlertid alle tilfredshed med de tilknyttede studerende. De udtrykte ligeledes, at de studerende havde medvirket til at udfordre forskerne/underviserne som herigennem kom til at føle
sig mere afklarede i forhold til eget projekt, hvilket havde dette ført til en forbedring af projektet
I løbet af undersøgelsen konstaterede jeg en forskel mellem projektansvarlige med og uden formel forskerkompetence. Undervisere med forskerkompetence holdt fokus på meta- refleksioner samt validiteten i projektet, undervisere uden egentlig forskerkompetence fokuserede i højere grad på de studerendes læring i projektet.
(Foreløbige) resultater
Min hypotese er, at udviklingen fra underviser til forsker er en transformation, som studerende kan være med
til at facilitere. At blive forsker er ikke kun en erkendelse af, hvad det indebærer af krav til undersøgelses validitet, publiceringsresultater og anerkendelse i forskningsmiljøer, men også en udviklingsproces med en udvikling og et ændret fokus i arbejdet med videnudvikling.
Studerendes medvirken i forskningsprojekter stimulerer en forskningsfaglig bevidsthed hos den projektansvarlige
Konklusioner
1. At bevæge sig fra underviser til forsker er en transformation, hvor man efterhånden erfarer, hvad
forskning kræver og gradvist kan varetage mere selvstændig forskning
2. Studerende kan hjælpe i denne proces, hvor det er svært at orientere sig, da deres deltagelse skærper fokus på projektet
3. Forskeridentiteten kan efterhånden erstattes af en underviser-identitet jo længere, en forsker arbejder
i et undervisningsmiljø.
47
37. D-vitaminstatus hos danske elitesvømmere. Rikke Larsen, cand.scient. Human Ernæring,
Lektor, Professionsbacheloruddannelsen i Ernæring og Sundhed
Samarbejdsuniversitet/praksispartner
 Herlev Hospital (Nina Geiker)
 Institut for Human Ernæring, Københavns Universitet
(nu Institut for Idræt og Ernæring),
 Reservelæge Niklas Rye Jørgensen
 Videnskabelig assistent Mette Hansen
 Bioanalytiker Pia Madsen.
Baggrund, formål og relevans
Undersøgelser har vist, at den danske befolkning generelt har for lav D-vitaminstatus. Dyreforsøg såvel som
humanundersøgelser indikerer, at lav D-vitaminstatus reducerer muskelfunktionen. Elitesvømmere, der dyrker
idræt indendørs, kan tænkes at have lavere soleksponering og derved risiko for dårlig D-vitaminstatus med
indvirkning på deres præstationsevne.
Metoder
29 danske elitesvømmere (16-24 år) deltog (12 piger og 17 drenge). Der blev foretaget enkelt statusmålinger
af svømmernes s-25(OH)D, s-PTH og albuminkorrigeret kalcium i marts-april.
D-vitamin- og kalciumindtag blev estimeret vha. et fødevarefrekvensspørgeskema.
Antropometriske data blev indhentet og muskelstyrke blev målt vha. et hånddynamometer.
(Foreløbige) resultater
Der blev fundet sufficient D-vitaminstatus hos svømmerne (s-25(OHD): 54,7 nmol/l (median)). Kønsopdelt
havde drengene insufficient status (s-25(OH)D: 41,8 nmol/l)), mens pigerne var sufficiente (S-25(OH)D: 59,7
nmol/l). Opdelt i s-25(OH)D over og under 50 nmol/l blev der hos drengene fundet en signifikant forskel i
håndgrebsstyrke.
Konklusioner
D-vitaminstatus hos elitesvømmere blev fundet sufficient og ikke lavere end fundet hos den danske befolkning
generelt. Der var signifikant forskel mellem drengene og pigernes D-vitaminstatus. Resultaterne indikerer, at
insufficient D-vitaminstatus kan være medvirkende årsag til reduceret muskelfunktion.
48
38. Is Adolescent Body Weight Associated With Parental Beliefs About Overweight, Attitudes
Towards Food, and the Home Environment? Alexandr Parlesak, Ph.D., Dr. Habil., Bachelor's
Degree in Global Nutrition and Health
Partner University/ Collaboration Partner
 McGill University, Clinical and Health Informatics Research Group,
Montréal, Canada (Dörthe Krömker and Zhe Tian)
 University of Applied Sciences Fresenius, Idstein, Germany (Andreas
Stolberg)
 Zurich University of Applied Sciences, Wädenswil, Switzerland (Claudia
Müller)
Background, aim and relevance
A better understanding of the interaction between the parents’ attitudes and their children’s weight status is
mandatory to better prevent childhood obesity development.
Methods
This study investigated parents’ attitudes towards food (price, identity, cooking, ecology, mood, dieting, convenience, functionality), social cognitions concerning overweight (risk perception, self-efficacy and response
efficacy for exercising and healthy eating) and characteristics of the home environment (restriction of snacks,
regular family meals, parents involved in sports) and their association with their children’s zBMI, in adolescents aged 12-19 years.
(Preliminary) Results
In a non-clinical sample of 842 parent-adolescent dyads we found that the zBMI is most strongly and positively associated with parental dieting attitudes and negatively with parents’ self-efficacy to motivate their children
to exercise. The zBMI is negatively and weakly associated with dislike of cooking, identification with the way of
eating and the perceived benefit of healthy eating (response efficacy).
Conclusions
Our results indicate that parents’ lack of successful weight management strategies is more clearly associated
with their children’s weight status than with a lack of problem awareness. Current dieting attempts especially
need to be replaced with more successful strategies.
49
Institut for Sundhedsfaglig og Teknologisk Efter- og Videreuddannelse
39. Hvordan kan sundhedsplejersken understøtte handlekompetence, når piger i udskoling
møder udfordringer i forhold til mental sundhed i det postmoderne samfund? Julie Rothaus
Voss Rathsach, Sundhedsplejerske, Sygeplejerske
Samarbejdsuniversitet/praksispartner
Ingen angivet
Baggrund, formål og relevans
Mental sundhed er både en forudsætning for udvikling og læring, og en beskyttende faktor for risikoadfærd og
udvikling af sygdom. I 2005 anslog WHO at op imod 20% af alle skolebørn led af mentale sundhedsproblemer. Disse tal understøttes af Statens Institut for Folkesundheds ”Skolebørnsundersøgelse” fra 2014, som
viste at de unges mentale sundhed er forværret de sidste 4 år. Vidensråd for Forebyggelse konkluderede
desuden at dette tal har været sigende de sidste 20 år. Specielt er 11-15-årige piger hårdt ramt. Formålet med
projektet er at undersøge hvorledes skolesundhedsplejen kan understøtte unges handlekompetence i forhold
til deres mentale sundhed
Metoder
Projektet tager udgangspunkt i et semistruktureret fokusgruppeinterview med 8 piger i alderen 14-15 år. Med
denne metode ønskes et nuanceret billede af pigernes oplevelser og erfaringer i forhold til deres mentale
sundhed, samt et indblik i deres oplevelser af mødet med sundhedsplejersken.
(Foreløbige) resultater
Interviewundersøgelsen viste at pigerne følte sig presset og stresset over konstant at skulle træffe valg og
fravalg. De følte et forventningspres fra såvel forældre, skole og fra dem selv. Fælleskabet med kammeraterne betyder meget, samtidigt med at det er medvirkende til, at de føler sig presset. Pigerne udtrykte behov for
at kunne dele disse oplevelser med en, som de havde en relation til og som anerkendte dem for dem, de er.
Her kunne sundhedsplejersken have en rolle, hvis hun var mere synlig og tilgængelig.
Konklusioner
Sundhedsplejersken kan understøtte unges handlekompetence i forhold til deres egen mentale sundhed ved
at have en helhedsorienteret tilgang til de unge og tage udgangspunkt i den livsverden, de unge befinder sig i.
En livsverden, der stiller krav om valg og fravalg. Her er en anerkendende sundhedspædagogisk tilgang vigtig med orientering mod ægte deltagelse. Sundhedsplejersken skal reflektere over sin rolle på skolen og sin
relationen til de unge samt medtænke tværfagligt samarbejde med det øvrige personale.
50
Forskningsservice fra Biblioteket Metropol
40. Forskningsservice fra Biblioteket Metropol. Anna Møbjerg, informationsspecialist, Bente Larsen, informationsspecialist, Lene Kaad, informationsspecialist, Trine Azbi, afdelingsleder i biblioteket (kontaktperson).
Baggrund, formål og relevans
I forbindelse med Metropols strategi 2020 – Undervisere der forsker, oplever biblioteket en stigende interesse og behov for særlige
biblioteksservices rettet mod forskningsunderstøttelse.
Biblioteket tilbyder derfor ansatte at få hjælp i deres arbejde med
forskning- og udviklingsprojekter.
På dette års forskningsdag vil biblioteket præsentere bibliotekets
forskningsservice.
Metoder
En posterpræsentation der viser eksempler på bibliotekets service og de værktøjer der benyttes.
På posteren informeres om
 Brug af bibliotekets e-ressourcer i 2014 (opgørelse af artikeldownload, artikelbestillinger og brug af databaser)

Bibliotekssupport til ansattes FoU-aktiviteter (eksempler på projekter biblioteket har bidraget til)

Studenterrapporter 2014 (opgørelse fra Studenterportalen og UC Viden)

Metropol ansattes publicering og citering (opgørelse fra Web of Science (WoS) og Scopus)

Ansattes videnproduktion 2014 (opgørelse fra UC Viden fordelt på typer, på autoritetslister mv.)
Der laves desuden flyers/bogmærker om Open Access (OA) og ORCID (forsker-ID)
(Foreløbige) resultater
Løbende udvikling og tilpasning af bibliotekets services, som regelmæssigt overensstemmes med de ansattes
behov. Foreløbig med positiv feedback fra brugere, der har kendskab til og benytter bibliotekets service.
Konklusioner
Biblioteket udbygger i øjeblikket forskningsservice for ansatte og er i gang med at implementere særlige services der understøtter hjælp til publicering, fondsansøgninger, citationsanalyser mm.
51
Posterpræsentationer – Hold 2
Institut for Sygepleje
41. Involvering og egenomsorg blandt ældre kronisk syge borgere i hjemmesygeplejen. Kathrine H. Pii, cand.mag., ph.d., Gerd Halskov, cand.cur., ph.d., Institut for sygepleje.
Samarbejdsuniversitet/praksispartner
 Københavns Kommunes Sundheds og Omsorgsforvaltning, Amager hjemMesygeplejeenhed.
Baggrund, formål og relevans
Det stigende antal ældre kronisk syge borgere, der modtager hjemmesygepleje, har medført et politisk fokus
på borgerinvolvering og potentialet for at øge borgeres aktive deltagelse i egen pleje og behandling i det primære sundhedsvæsen. Det er imidlertid uudforsket, hvor meget pleje- og behandlingsansvar hjemmesygeplejen kan uddelegere til borgerne, uden det indebærer utryghed og risici for borgerne.
Projektet undersøger, hvordan ældre kronisk syge borgere aktuelt involveres i deres pleje og behandling i
hjemmesygeplejen og belyser de udfordringer og muligheder, der er forbundet med at involvere disse borgere
i deres pleje og behandling på en faglig forsvarlig måde.
Metoder
Undersøgelsen bygger på interview med ældre, kronisk syge borgere der modtager hjemmesygepleje samt
etnografisk feltarbejde blandt hjemmesygeplejersker og de ældre kronisk syge borgere.
(Foreløbige) resultater
Borgeres forståelse af involvering handler om at føle sig respekteret og indgå i et ligeværdigt og dialogbaseret samarbejde med hjemmesygeplejersken snarere end at påtage sig pleje og behandlingsopgaver.
Borgeres viden om sundhedsfremmende pleje, behandling og aktiviteter og motivation for at deltage aktivt har
afgørende betydning for, om de er i stand til at varetage egen pleje og behandling på en faglig forsvarlig måde. Hos flere borgere er deres viden om egen sygdom og relateret pleje og behandling ikke tilstrækkelig for at
kunne yde egenomsorg på en faglig forsvarlig måde. Borgeres motivation for egenomsorg er desuden foranderlig og påvirkes af udviklingen af deres sygdom.
Konklusioner
Den sundhedspolitiske dagsorden for borgerinvolvering er mere vidtrækkende end borgeres forståelse af,
hvad involvering indebærer, og hjemmesygeplejersker får dermed til opgave at mediere denne forskel.
Borgeres viden og motivation udgør et vigtigt indsatsområde for hjemmesygeplejersken. Ved at sikre at borgere har tilstrækkelig viden om deres sygdom og relateret pleje og behandling, kan hjemmesygeplejersken
fremme borgeres egenomsorg. Dog kræver borgeres foranderlige motivation for egenomsorg kontinuerlig
monitorering og faglig støtte i egenomsorgen for at sikre tryghed, kvalitet og sikkerhed.
52
42. A constipation is casting a shadow over everyday life – a systematic review on elderly
people’s experience of living with constipation. Nina Tvistholm, sygeplejerske, Master of Humanities and Health Studies MHH, Lene Munch, sygeplejerske, cand.scient.san.
Partner University/ Collaboration Partner
 Gentofte Hospital
Background, aim and relevance
Aim: To explore and summarize how constipation affects the daily living of the elderly from their own perspective. Furthermore, to assess how interventions aimed at treating constipation in the elderly affect patientreported outcome such as quality of life.
Constipation is a common and overlooked problem with an impact on everyday life, especially among the
elderly. Older people seem to make individual preconceptions on constipation which can influence the strategies used to prevent and treat constipation.
Methods
A systematic review, integrating findings from both qualitative and quantitative studies. Systematic searches
were carried out in PubMed, CINAHL, PsycINFO and Embase on the 31th of July. A search strategy was constructed with key concepts identified using PICO to identify quantitative studies and PIC(o) to identify qualitative studies. Search terms included constipation, elderly, aged, elderly people, aged people, quality of life,
patient experience, patient perspective, meaning, emotion, psychological. Reference lists were searched
manually.
Results
A total of nine studies were included in the review, five quantitative and four qualitative. Three main themes
occurred from the results of the included studies: bodily experiences, everyday life shadowed by constipation
and mental impairment.
Conclusions
Constipation among the elderly was connected to subjective and comprehensive experiences. It had a negative impact on physical and mental well-being as well as the social life of the elderly. The review also showed
that the elderly had individual and personal strategies, based on their own beliefs.
53
43. Adult Attachment and PTSD or depression symptoms during Rehabilitation of Women
newly Diagnosed with Gynaecological Cancer. Kamila Adellund Holt, Lecturer, cand.scient.san.,
Ph.D.
Partner University/ Collaboration Partner
 Institute of Clinical Research, Research Unit of Gynaecology and
Obstetrics, University of Southern Denmark and Department of Obstetrics
and Gynaecology, Odense University Hospital (Pernille Tine Jensen, Post
doc,MD, Ph.D., Ole Mogensen Professor, Dr.Med.)
 Institute of Public Health, National Research Centre of Cancer Rehabilitation, University of Southern Denmark (Dorte Gilsaa Hansen, Associate
Professor, MD, PhD.)
 Institute of Psychology, Danish Research Unit of Psychological Trauma,
University of Southern Denmark (Ask Elklit, Professor, cand.psych.)
Background, aim and relevance
Research has shown that adult attachment influences on humane experiences with chronic disease, health
behaviour, symptom perception and health-care utilisation. Adult attachment is an individual characteristic and
in the context of cancer rehabilitation investigation of this phenomenon may contribute to understanding the
expectations of the patient to individually adjusted cancer rehabilitation.
The primary aim was to explore adult attachment among women newly diagnosed with gynaecological cancer.
Secondary, we investigated depression, post-traumatic stress disorder (PTSD) and quality of life (EORTC
QLQ-C30 generic and disease specific patient questionnaires) within a 5-months follow-up during rehabilitation.
Methods
We include 151 women, aged 20–75 years, treated surgically for endometrial, cervical or ovarian cancer. The
study had a longitudinal observational study design with patient-reported outcome and goal-oriented rehabilitation. The rehabilitation consisted of two nurse consultations and two telephone conversations. Attachment,
mental symptoms and quality of life were measured at baseline and after 5 months.
Results
We found significant positive changes within the attachment anxiety dimension among women with ovarian
cancer, a significant reduction of PTSD among endometrial cancer patients and insignificant changes in depression among all cancer types. The attachment anxiety dimension significantly increased the odds for PTSD
and depression.
Conclusions
A purposeful focus on women's attachment dimensions may improve individually adjusted support care and
rehabilitation. The rehabilitation activities should focus on women's symptoms of depression and PTSD.
54
Institut for Fysioterapi og Ergoterapi
44. Præsentation af ergoterapeut-studerendes projekter fra Sommerskolen 2015.
Samarbejdsuniversitet/praksispartner
 University College Sjælland
Baggrund, formål og relevans
Studerende med særlig talent og interesse tilbydes et intensivt ekstra curriculært sommerskoleforløb.
De studerende er sammen i grupper, hvor de udarbejder en problembaggrund, søger relevant litteratur til at
belyse deres problemfelt, diskuterer litteraturen i journal-clubs, uddrager essensen og udarbejder derefter en
poster med tilhørende hand-outs over deres resultater. Posterfremstilling udgør således en del af forløbet.
Metoder
På sommerskole-kurset er fokus at udvikle studerendes talenter indenfor litteraturstudier. Ergoterapeutstuderende fra to institutioner forholder sig til en selvvalgt population gennem anvendelse af begreber fra aktivitetsvidenskab. Indholdsmæssigt arbejdes med ergoterapiprofessionens videnskabsgrundlag og på aktivitet i en
bred forståelse. Fx på aktiviteters betydning for udvikling og fastholdelse af identitet (occupational identity),
samt på nødvendigheden i at have mulighed for at udøve aktiviteter og konsekvenserne, hvis man frarøves
mulighed for aktivitet (occupational deprivation).
(Foreløbige) resultater
Via litteraturen afdækkes relevante forhold, hvilket præsenteres på postere. De fire bedste postere præmieres
med mulighed for at komme på Forskningsdagen. De fire udvalgte postere belyser følgende problematikker:




Hvordan oplever hjemløse deltagelse i deres daglige aktiviteter?
Hvordan oplever fængselsindsatte deres muligheder for deltagelse i dagligdagsaktiviteter?
Er der sammenhæng mellem kvinders oplevelse af aktivitetsbalance og stress?
Hvordan formes gadeprostitueredes identitet gennem deres daglige aktiviteter?
55
45. Tilfredshed med daglige aktiviteter hos asylansøgere i Danmark. Anne-Le Morville, ergoterapeut, ph.d., lektor, Ergoterapeutuddannelsen
Samarbejdsuniversitet/praksispartner
 Department of Health Sciences, Lund Universitet, Sverige
 Parker Instituttet, reumatologisk afdeling, Bispebjerg og Frederiksberg Hospitaler, Danmark
Baggrund, formål og relevans
Begrænsede muligheder for aktivitet i danske asylcentre gør det relevant at undersøge asylansøgeres tilfredshed med aktiviteter og aktivitetsniveau. Lavt aktivitets og -tilfredshedsniveau, kan medføre tab af ADLevne og dårligt helbred. Tortur og selvvurderet helbred kan associeres med ADL-evne, men det er uvist om
det gælder aktivitetsniveau og tilfredshed.
Målet var:
At beskrive asylansøgeres aktivitetsniveau og -tilfredshed i danske asylcentre, samt om aktivitetsniveau og tilfredshed ændredes over tid.
At afdække om faktorer som tortur, selvvurderet helbred og ADL-evne var relateret til aktivitetsniveau og tilfredshed.
Metoder
43 asylansøgere ved baseline og 17 ved followup blev inkluderet. Spørgeskemaet Satisfaction with Daily Occupations (SDO), samt andre redskaber blev anvendt.
Resultater
Studiet viste lav tilfredshed med aktiviteterne. Der var ikke statistisk signifikante ændringer fra baseline til follow-up, hvad angår aktivitetsniveau og tilfredshed. Der var ikke signifikant forskel mellem torturerede/ikke
torturerede ved baseline eller follow-up. Der var signifikant sammenhæng mellem psykiske symptomer og
aktivitetsniveau og tilfredshed ved follow-up.
Konklusioner
Asylansøgere oplevede lav tilfredshed med daglige aktiviteter, efter ankomst og efter 10 måneder i asylcentret, dette var ikke relateret til tortur. Der er tegn på sammenhæng mellem et højt aktivitetsniveau over tid og
lavere forekomst af psykiske lidelser. Der foreslås mere forskning og udvikling af aktivitetsrettet rehabilitering
og forebyggelse for denne gruppe.
56
46. Rapid knee extensions to increase quadriceps muscle activity after total knee arthroplasty: A randomized cross-over study. Louisa Wilquin, adjunkt, cand.scient., Fysioterapeutuddannelsen
Partner University/ Collaboration Partner
 Physical Medicine & Rehabilitation Research - Copenhagen (PMR-C)
Background, aim and relevance
Loss of knee-extension strength is pronounced after total knee arthroplasty (TKA), primarily due to inability of
the central nervous system to activate the quadriceps muscle caused by inhibition. Rapid knee extensions
may be a simple way to reduce quadriceps muscle inhibition after surgery.
The aim was to examine how fast patients could perform rapid knee extensions early after TKA and the degree to which these induced greater quadriceps muscle (EMG) activity compared to slow knee extensions.
We hypothesized rapid knee extensions to increase quadriceps activation more than slow knee extensions,
without inducing a higher level of pain.
Methods
Patients, 4-8 weeks after TKA randomly performed 5 rapid (with an intended maximal acceleration) and 5 slow
knee extensions with the operated leg at a load of 10 RM. Surface EMG was measured in the medial (VM)
and lateral (VL) vastii of the quadriceps muscle. The primary outcome was mean of the 5 peak EMG amplitudes of the rapid and slow knee extensions respectively, normalized to the corresponding MVC, and expressed as %EMGmax.
(Preliminary) Results
Slow knee extensions were performed at a median angular velocity of 19.7°/sec (16.0-22.6) and rapid at
51.4°/sec (36.2-58.5). Muscle activity was significantly higher during rapid knee extensions (120.2 %EMGmax
(98.3-149.1)) compared to slow (106.0 %EMGmax (88.8-140.8)) for VL (p<0.01). No difference was observed
for VM between rapid (120.8 %EMGmax (90.4-134.0) and slow (121.8 %EMGmax (93.0-133.0)) knee extensions, respectively (P=0.17).
Conclusions
Patients more than doubled their contraction velocity during rapid knee extensions compared to slow. This
was associated with an increase in VL muscle activity of 8.5%EMGmax, the same effect was not observed for
VM.
57
47. Effects of two different intensities of a single bout of acute exercise performed postlearning on consolidation and retention of motor memory. Marie Kraft, Fysioterapeut,
cand.scient. i Humanfysiologi
Partner University/ Collaboration Partner
The experiments in this master thesis are part of Richard
Thomas ongoing Ph.D. project headed by Jesper LundbyeJensen and in collaboration with Department of Nutrition, Exercise and Sports and Copenhagen Centre for Team Sport
and Health, Copenhagen University.
Background, aim and relevance
Acute exercise has been shown to have positive effects on the brain, in terms of both cognitive functions and
motor skills. The aim of the present randomised controlled trial was to investigate the effects of two different
intensities of acute exercise performed post-learning on visuomotor skill learning.
Methods
The study consisted of quantitative measurements of performance in a visuomotor accuracy task (VT) during
acquisition and at retention tests twenty-four and seven days after acquisition. During acquisition of VP, the
subjects accomplished five blocks of twenty trials while receiving feedback and during retention tests one
block à twenty trials without feedback. Post-acquisition the subjects were randomised into three groups
matching according to age, weight, height, BMI, maximal effect, VO2max and baseline motor performance; Two
groups exercising for 3 x 3 minutes either at moderate or high intensity and a control group resting for twenty
minutes. Blood lactate concentration, heart rate and rate of perceived exertion (Borg) was measured during
and following exercise.
(Preliminary) Results
Thirty-six healthy men at the age of twenty to twenty-eight years were included. Analysis of variance showed
significant improvement in performance for all groups during acquisition of VT, and no between-group difference. Analysis of variance of performances at end of acquisition and retention tests showed significantly improvement for the high intensity group compared to the control group. A tendency to interaction between
GROUP and TIME was found. Significant correlation was found between rate of perceived exertion and
change in motor performance.
Conclusions
Compared to a resting condition, a single bout of high intensity acute exercise after acquisition can facilitate
consolidation and retention of a newly-learned visuomotor accuracy task. Moderate intensity exercise was not
accompanied by this effect.
58
48. Association between maximal hamstring muscle strength and hamstring muscle preactivity during a movement associated with non-contact ACL injury. Mette Kreutzfeldt Zebis,
M.Sc., Ph.D.
Partner University/ Collaboration Partner
 Copenhagen University Hospital, Amager-Hvidovre
Background, aim and relevance
Reduced hamstring pre-activity during sidecutting may predispose for non-contact ACL injury. During the last
decade resistance training of the lower limb muscles has become an integral part of ACL injury prevention in
e.g. soccer and handball. However, it is not known whether a strong hamstring (ACL-agonist) musculature is
associated with a high level of hamstring muscle pre-activity during high risk movements such as sidecutting.
Thus, the aim of the present study was to investigate the correlation between maximal hamstring muscle
strength and the level of muscle pre-activity during sidecutting.
Methods
Eighty-five female handball and soccer players (17 ± 1 year) were screened for neuromuscular pre-activity in
medial (ST) and lateral (BF) hamstring muscle during a sidecutting maneuver. Maximal isometric hamstring
muscle strength [N/kg BW] (MVC) was measured by a handheld dynamometer. Neuromuscular activity calculated as average EMG amplitude obtained during sidecutting in the 10 ms interval prior to initial contact (IC)
was normalized to peak EMG amplitude obtained during MVC (% of max EMG). The correlation between %
EMG pre-activity (mean of ST and BF) and MVC was evaluated by Spearman rank correlation analysis.
(Preliminary) Results
The correlation coefficient (rs) between hamstring pre-landing EMG activity and MVC was 0.109 (P=0.319).
Conclusions
No direct association was observed between preparatory hamstring muscle activity and MVC. This indicates
that high muscle strength may not per se translate into high levels of muscle pre-activity during movements
like the sidecutting maneuver.
59
49. Comparison of cardiopulmonary exercise testing (CPET) and oxygen consumption in
arm-cranking and ergometer cycling: a systematic review and meta-analysis. Rasmus Tolstrup Larsen, Physiotherapist
Partner University/ Collaboration Partner
 CopenRehab, Department of Public Health, University of
Copenhagen
 Ph.D. fellow Jan Christensen
 Ph.D. fellow Lars Hermann Tang
Background, aim and relevance
The VO2max works as a predictor for all-around health and determines the risk for mortality, survival rate in
patients undergoing major surgery, postoperative complications, lifestyle disorders, and quality of life. The
golden standard is on a leg cycle ergometer. Some patients will have discomfort and difficulties exercising at
maximal effort by the legs. Therefore in some cases, CPET performed by the upper body (CPET UB) is preferable. CPET by arm crank ergometer (AC) is a dynamic and safe method to test the oxygen consumption by
the upper body. A lack of knowledge exists on the upper body test, despite testing and comparison between
CPETUB and CPETLB has been made for years. The purpose of this systematic review and meta-analysis is to
provide insight and to quantify the ratio between CPETUB and CPETLB and hereby to create values for use in
future clinical testing.
Methods
A systematic search of MEDLINE, EMBASE, CINAHL, and Pedro databases was undertaken in March 2015.
Studies were required to report data on CPET UB and CPETLB. The outcome had to be VO2max. The Quality Assessment Tool for Observational Cohort and Cross-Sectional studies (QAT) assessed the methodological
quality of the studies included. Exclusion and assessment by the QAT has been and will be done by two independent writers.
(Preliminary) Results
2683 potential studies were identified by the search. After screening and title/abstract read 173 were included
for full text read. 48 studies are included for methodological QA and further data extraction.
Conclusions
With the systematic review and meta-analysis, we aim to give reference values to use CPET UB as a reliable
tool to estimate the VO2max.
60
Institut for Teknologi
50. Fuldgenomsekventering af methicillinresistente Staphylococcus aureus (MRSA) med fokus på mobile genetiske elementer. Lone Dons, cand.polyt., ph.d., Bioanalytikeruddannelsen
Samarbejdsuniversitet
 Klinisk Biokemisk Afdeling på Rigshospitalet
Baggrund, formål og relevans
Infektioner med MRSA-bakterier spænder fra overfladiske sår og bylder til hjerteklapbetændelse og blodforgiftning. Da MRSA-bakterier er resistente mod mange antibiotika, kan infektionerne være alvorlige og nogle
gange umulige at behandle. Bakterierne er kendetegnet ved hurtigt at kunne ændre sig, og det fører til dannelse af nye stammer med en højere grad af sygdomsfremkaldende evne (mere virulente) og som er mere
resistente mod antibiotika. Det er vist i studier, at mobile genetiske elementer, SaPI (S. aureus pathogenicity
islands) indeholdende virulensgener og antibiotikaresistensgener spredes blandt bakterierne. Denne genoverførsel medfører, at MRSA hurtigt kan tilpasse sig nye antibiotika og nye værter, samt at bakterierne kan få en
forøget virulens. I projektet vil vi benytte fuldgenomsekventering af MRSA-stammer. Ved analyse af sekvensdata vil vi kunne identificere og analysere de mobile genelementer i MRSA-genomer specielt m.h.t. resistens
og sygdomsfremkaldende faktorer. Herved vil vi få bedre forståelse for de mekanismer, som er involverede i
MRSA-bakteriernes evne til at sprede sig og forårsage infektioner.
Metoder
Bakterier genomer bliver sekventeret ved Next Generation Sequecing (NGS) metoden. DNA-sekvens data
bliver analyseret ved bioinformatiske metoder.
(Foreløbige) resultater
Det foreligger ikke resultater eller konklusioner på nuværende tidspunkt
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51. Resistensbestemmelse af gærsvampe – En metodesammenligning af Sensititre YeastOne
og Epsilometer test. Danilo Kalezic & Sandie Nhatien Vu, Bioanalytikere og dimittender fra Bioanalytikeruddannelsen, vejleder Minna Fyhn Lykke Llado, lektor, Bioanalytikeruddannelsen
Samarbejdsuniversitet
 Klinisk Mikrobiologisk afdeling, Rigshospitalet, Klinisk underviser Mette Jørgensen.
Baggrund, formål og relevans
Antallet af candidainfektioner er stigende i Danmark. Ligeledes er der en stigende resistensudvikling overfor
flere anvendte antimykotika. Der er derfor et behov for en mere præcis og hurtig resistensbestemmelse.
Metoder
Resistensbestemmelse vurderes ud fra antimykotikas evne til at hæmme gærsvampes vækst vha. Minimum
Inhibitory Concentration (MIC). Ved E-test bestemmes MIC på baggrund af en prædefineret koncentrationsgradient af 1 specifikt antimykotikum, mens Sensititre YeastOne bestemmer MIC for op til 9 antimykotika pr.
analysekørsel. Vi har her sammenlignet metoderne mht. præcision ifølge fastsatte krav fra European Committee on Antimicrobial Susceptibility Testing (EUCAST). E-test benyttes som den gyldne standard.
(Foreløbige) resultater
Der var god overensstemmelse mellem E-test og Sensititre. YeastOne for flere af de testede antimykotika
med en samlet overensstemmelse på 93 %. Sensititre. YeastOne kunne i nogle situationer bestemme MIC
hurtigere og havde færre variationer ved aflæsningsreglerne end E-test.
Konklusioner
De to metoder viste god overensstemmelse. Aflæsningen fandtes nemmere ved Sensititre YeastOne end ved
brug af E-test og derfor et godt alternativ i klinisk brug.
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52. Detection/characterization of Tn5801-like mobile genetic elements in tetracycline resistant staphylococci from pets and humans in Denmark. Lisbeth Elvira de Vries, Lecturer,
Ph.D., Academy Profession Degree Programme in Chemical and Biotechnical Science, Henrik
Hasman and Yvonne Agersø, Senior Senior Reseachers, DTU-FOOD
Partner University/Collaboration Partner
 National Food Institute, Technical University of Co
penhagen (Henrik Hasman and Yvonne Agersø)
Background, aim and relevance
The emergence of antibiotic resistance (AR) among pathogenic bacteria is a general problem and regarded as
a threat to public health in many countries. AR in pathogens is often associated with mobile genetic elements
(MGEs) that can transfer AR-genes within and between bacteria from humans and/or animals. AR-bacteria
from an animal host can transmit to a human host, where it can transfer AR-genes by MGEs to human bacteria, or vice versa. This study investigates the presences of Tn5801-like-MGEs carrying the tetracyclineresistance-gene, tet(M) in clinical Staphylococcus pseudintermedius from pets which confer a likely reservoir
of these elements detected in human Staphylococcus aureus.
Methods
27 tetracycline-resistant diagnostic S. pseudintermedius-isolates (1998-2005) from Danish pets were PCRscreened for tet(M). Selected isolates (13) were PCR-screened for MGE-specific genes and sequenced for
tet(M) (sanger-method). Long PCR-mappings and whole-genome-sequencing (Illumina) were performed for
selected S. pseudintermedius-isolates (7 and 3, respectively) and human S. aureus-isolates (1957-2000)
known to carry Tn5801-like-MGEs (7 and 1, respectively). Whole-genome-sequences (4) were annotated and
characterized using NCBI- PGAAP and CLC-Genome-Workbench. Characterized Tn5801-like-MGEs were
compared to sequences submitted to NCBI-GenBank.
Results
All 27 S. pseudintermedius-isolates were positive for tet(M). Out of 13 selected isolates 7 contained Tn5801like-MGEs and 6 Tn916-like-MGEs. Two different Tn5801-like-MGE-types (one novel) were detected among
the tested S. pseudintermedius-isolates (SP-MGE-type 1 and 2) and one distinct Tn5801-like-MGE-type was
detected among the human S. aureus-isolates. SP-MGE-type 1 and 2 showed very high similarity
(25807/25814=99.97% and 20617/20621=99.99% base-pair-identity) compared to GenBank-sequences from
human pathogens (Enterococcus faecalis strain-62/ Streptococcus agalactiae COH1 and S. aureus Mu50).
Conclusions
Tn5801-like-MGEs appear to be common in tetracycline-resistant S. pseudintermedius in Denmark. Almost
identical Tn5801-like-MGEs can be found in different gram positive species of pet and human origin suggesting that horizontal transfer of these elements has occurred between S. pseudintermedius from pets and human pathogens.
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53. Optimering af produktion af koldpresset juice ift. vitamin, mineral- og bakterieindhold.
Merete Norsker Bergsøe, adjunkt, ph.d., Lamia Mohamad Saad, adjunkt, cand. pharm., Pernille
Sebnem Salvarli, laborant, tekniker og Lars Holm Rasmussen, adjunkt, ph.d. Laborant- og Procesteknologuddannelserne
Samarbejdsuniversitet/praksispartner
 Frankly Juice ApS.
 Praksisnær Innovation v. Styrelsen for Videregående
Uddannelser, Uddannelses- og Forskningsministeriet.
Baggrund, formål og relevans
Frankly Juice ApS er en økologisk juiceproducent, der ønsker at styrke økologi og højne andelen af naturlige
råvarer i danskernes kost. Frankly Juice baserer produktionen på friske økologiske råvarer, der koldpresses
skånsomt mhp. at bevare råvarernes høje indhold af næringstoffer. Råvarevalg og produktionsform har begge
effekt på næringsindhold såvel som holdbarheden af juice, idet forskellige almindeligt brugte produktionsmetoder i juice-industrien har forskellig effektivitet ift. at ekstrahere råvarernes indhold af bioaktive stoffer som
antioxidanter og stoffer med antibakteriel effekt.
Formålet med projektet er at generere ny viden om produktion af koldpresset juice. Resultaterne vil blive anvendt til at optimere produktionen af Frankly Juice's produkter, således at næringsstofindhold højnes samtidigt
med at produkterne holder bedre.
Metoder
Projektet gennemføres af Metropols og Frankly Juices personale med det produktionsudstyr og de økologiske
råvarer, som Frankly Juice ApS anvender i den daglige produktion (april–december 2015). Projektet vil undersøge 3-5 juicer fra Frankly Juice ApS' sortiment. Til metodesammenligning anvendes produktionsformerne
koldpresning og centrifugering. Juiceprøver analyseres for mineralindhold (AAS) og vitaminindhold (HPLCUVVIS/DAD) samt bakterieindhold (total-kim). Projektet bygger på et eksisterende uformelt samarbejde mellem parterne, hvor laborantstuderende ifm. undervisningen har karakteriseret forskellige produkter fra Frankly
Juice (siden oktober 2014).
(Foreløbige) resultater
Projektet er et eksempel på, hvorledes et uformelt samarbejde i regi af undervisningen kan udvikle sig til et
decideret udviklingsprojekt, hvor der indhentes ekstern finansiering til betaling af undervisere for deres indsats
som udviklingskonsulenter/forskere. Foreløbige resultater viser, at Frankly Juice’s koldpressede produkter
næringsstofmæssigt er på linje med tilsvarende produkter. Indholdet af vitamin C er højere end almindelig
juice, mens mineralindholdet er sammenligneligt. Der er generelt set ikke problemer med mikrobiel aktivitet.
Der gennemføres i perioden august til november et sammenlignende studie af produktionsformer.
Konklusioner
Det er muligt at udvikle uformelle samarbejdsformer fra undervisningen til eksternt finansierede FoUaktiviteter. Konkrete resultater fra de planlagte eksperimenter vil blive inkluderet i posteren.
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54. Comparison of STIR and T2 FAT SAT in bone bruise imaging for occult scaphoid fracture.
Louise Meincke, graduate from the Bachelor's Degree Programme in Radiography.
Partner University/ Collaboration Partner
 Copenhagen University Hospital Herlev, Gentofte,
Radiology Section (Dimitar Ivanov Radev, MD)
 Metropolitan University College, Bachelor's Degree
Programme in Radiography (Carsten Ammitzbøl
Lauridsen, Ph.D.)
Background, aim and relevance
Fat suppression is an essential technique in MRI musculoskeletal imaging, particularly used to improve the
detection of bone bruise. However, MRI offers a variety of fat suppression sequences and in order to examine
bone bruise, several sequences are appropriate. It is of great importance for the diagnostic accuracy, that
radiographers and radiologists are aware of the advantages and disadvantages related to the various sequences.
The purpose of this prospective study was, by specific physical settings, to compare the fast short tau inversion recovery (STIR) and fast spin echo sequence (FATSAT) in the sectional direction along the os. Scaphoid
axis. The study evaluates which sequence is the best qualified for the visualization of posttraumatic bone
bruise in MRI musculoskeletal imaging.
Methods
Three readers (one radiographer and two experienced MRI radiologists) performed the evaluation based on
an assessment of the concepts of size (area) and image quality (contrast (C) and contrast to noise ratio
(CNR). Fifty-one patients from a 11 month period were included in the study. A p-value < 0.05 was considered
statistically significant. Data were analyzed by unpaired Student's t-test and Pearson correlation
analysis. The MRI scans were executed on a 1.5 T extremity scanner including a FATSAT and STIR sequence with (TR/TE 3100/100ms) and (TR/TE 2000/35ms) respectively.
(Preliminary) Results
There was no significant difference comparing bone bruise area (p > 0.05) or CNR on STIR and T2 FAT SAT
respectively. Mean/SD for the three readers were 62.7/44.0, 65.9/46.1 and 67.3/46.9 respectively. However C
showed significant difference in favor of T2 FAT SAT for all three readers (P<0.0001). Mean/SD values for
image contrast for the three readers were 0.6/0.2, 0.6/0.02 and 0.4/0.02 respectively.
Conclusions
An interchangeably usage of the two sequences was found acceptable for the diagnostic if the protocol is
properly composed. However, the T2 fat SAT sequence provides a higher image contrast.
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55. Dynamic Contrast Enhanced Computed Tomography: Effects of Non Rigid Motion Correction on image quality and reproducibility. Kevin Robert Brow og Simon Munch-Jensen, graduates from the Bachelor's Degree Programme in Radiography.
Partner University/ Collaboration Partner
 Department of Diagnostic Radiology,
Rigshospitalet, Copenhagen University Hospital
Background, aim and relevance
Image registration and motion correction constitute a general class of challenges that impact on many areas
of imaging and radiology. One specific area in which they may have a potential impact is in Dynamic Contrast
Enhanced Computed (DCE-CT). Unlike the head, neck, and pelvis, which are less prone to respiratory motion,
the liver is one of the most challenging organs for perfusion imaging, owing to considerable nonuniform and
large motion during respiration. For that reason the purpose of this study was to assess the extent in which
non-rigid motion correction (NRMC) effects both the accuracy of liver placement and the reproducibility of
perfusion value measurements of colorectal cancer liver metastases.
Methods
Liver placement measurements were performed on images from 16 DCECT examinations (with and without
NRMC). Paired t-tests were used to assess the difference between the two sets of images. Images (with and
without NRMC) from 5 DCECT examinations were utilized to assess the effect of NRMC on the reproducibility
of perfusion value measurements. Both small ROI and volume measuring methods were employed to measure perfusion values. Pearson correlation tests were used to assess reproducibility of the perfusion value
measurements collected by 3 observers.
(Preliminary) Results
There was a significant difference in the precision of liver placement in the image sets with applied NRMC,
compared to the image sets without NRMC, in 4 out of the 16 sets (p < 0.05). NRMC showed a positive effect
on the reproducibility of perfusion values when measured with small ROI`s. Results from the volume measuring method were indecisive and could not prove that NRMC had an effect on reproducibility.
Conclusions
This study showed that NRMC has a measurable effect on the precision of liver placement when applied to
DCE-CT images Furthermore, reproducibility of perfusion measurements completed with the small ROI method, was better with NRMC than without.
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Institut for Ernæring og Jordemoderkundskab
56. National klinisk retningslinje for behandling af dystoci hos førstegangsfødende (NKRDystoci) – udforskning af baggrund, antagelser og effekt af en evidensbaseret klinisk retningslinje. Lena Mariann Eriksen, Jordemoder, cand.scient.san., lektor, ph.d.-studerende, Jordemoderuddannelsen
Samarbejdsuniversitet/praksispartner
 Forskningsenheden Kvinders og Børns Sundhed, Juliane Marie Centret, Rigshospitalet
Baggrund, formål og relevans
I Danmark behandles op mod halvdelen af raske førstegangsfødende med vestimulation (Syntocinon-drop),
på grund af manglende fremgang i fødslen (dystoci). Vestimulation associeres med øget risiko for instrumentel forløsning, akut kejsersnit, føtal iltmangel, lav Apgar og lav pH hos den nyfødte. Der er dystoci i fødslen,
hvis livmodermunden ikke åbner sig med den forventede hastighed. I klinisk praksis er forventningen om, hvor
hurtigt livmodermunden bør åbne sig, baseret på data fra et ældre amerikansk studie af 200 fødsler. Validiteten og generaliserbarheden af studiet er omdiskuteret, og nyere forskning har vist, at livmodermundens åbningshastighed formentlig er anderledes end hidtil antaget, især i første del af fødslens aktive fase, hvor livmodermunden er mellem 4 og 6 cm åben.
Sundhedsstyrelsen udgav i november 2014 en national klinisk retningslinje for behandling af dystoci hos førstegangsfødende (NKR-Dystoci). NKR-Dystoci implementerede denne nyere forskning ved at opfordre til, at
der i større grad afventes fremgang i fødslen uden brug af vestimulerende indgreb, samt at dystoci-diagnosen
bør overvejes nøje, hvis livmodermunden er mellem 4 og 6 cm åben. Sundhedsstyrelsen angiver, at NKRDystoci forhåbentlig kan reducere antallet af vestimulerende drop, kejsersnit, instrumentelle forløsninger og
nyfødte med iltmangel. Forskningsprojektets formål er at undersøge effekten af NKR-Dystoci på indgrebsfrekvenserne blandt førstegangsfødende og at opnå aktuel viden om diagnosticering og behandling af dystoci i
klinisk praksis i Danmark med sigte på at optimere omsorgen for førstegangsfødende kvinder.
Metoder
Projektet omfatter tre delstudier:
Delstudie 1 er et kvalitativt studie, der anlægger et STS-perspektiv (Science and Technology Studies) på,
hvordan dystoci konstrueres i klinisk praksis. Studiet udføres som et etnografisk feltstudie på en mindre dansk
fødeafdeling.
Delstudie 2 undersøger effekten af NKR-Dystoci på indgrebsfrekvenserne på nationalt og lokalt niveau ved
hjælp af metoden ”Interrupted Time Series Analysis” (ITS).
Delstudie 3 undersøger hvordan NKR-Dystoci påvirker variationen i indgrebsfrekvenserne mellem fødestederne.
(Foreløbige) resultater
Forventes i løbet af 2016.
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57. Hospital meals experiences and appetite – findings from a Danish study using qualitative
visual methods. Louise H. Nielsen, Bithe Poulsen og Danielle Søndergaard, Bachelors in Nutrition
and Health & Lise Justesen, Senior Lecturer, PhD, MSc Food Science
Partner University/ Collaboration Partner
 Holbæk Sygehus
 Koncern Service Køkken, Region Zealand,
Denmark
Background, aim and relevance
Insight into patients’ hospital meal experiences is a platform for nutritional care strategies. Nutritional care
strategies are important as 30-40% of patients are at risk of being undernourished. This study aimed to investigate patients’ meal experiences related to appetite during hospitalization.
Methods
9 hospitalized patients (≥3 days) from orthopaedic/surgical wards and 2 patients’ (≥3 days) from the gynaecological/surgical ward in a small Danish Hospital were interviewed during spring 2015 using a visual and semistructured interview method (Research-Driven-Photo-Elicitation). 5 transcribed interviews from orthopaedic/surgical department were coded and analyzed thematically inspired by Kvale and Brinkmanns analysis
strategy. 7 transcribed interviews from orthopaedic/surgical wards and 2 from gynaecological/surgical ward
were divided into themes using content analysis inspired by The Five Aspects Meal Model (FAMM).
(Preliminary) Results
Patients use food and meals as proxy for maintaining identity and autonomy in an alienating situation. Patients
found social aspect around meal situations, meal surroundings and food aesthetic expressions to be important
elements for improving appetite. Furthermore, patients’ appetite is positively affected by health care staff’s
ability to negotiate and co-construct patients’ meal experiences based upon patients’ own situated needs.
Conclusions
These findings emphasize the need for considering hospital meal experiences and patients appetite to be
socially and situationally constructed. According to the findings, health care professional’s ability to negotiate
and co-create patients meal experiences and appetite is important. There is a need to improve health care
professionals competences related to co-creation based upon patients’ individual and situated needs.
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58. ”Rigtige Måltider”. Udkast til en integral-perspektivistisk evidensmodel. Ulrik Houlind
Rasmussen, lektor, ph.d., Professionsbacheloruddannelsen i Ernæring og Sundhed
Baggrund, formål og relevans
Der stilles stadig flere krav til evidens i det sundhedsprofessionelle arbejde. Evidensbegrebet er imidlertid alt
andet end evident. Forvirringen er stor og orienteringen vanskeliggjort af mange, tilsyneladende modstridende
evidensforståelser, der truer med at gøre sundhedsfaglige diskussioner og uenigheder ufrugtbare, hvis ikke
ligefrem meningsløse. Der synes derfor at være et stigende behov for en grundlæggende videnskabsteoretisk
afklaring af, hvilke elementære former for evidens, der findes i det sundhedsprofessionelle arbejde, deres
respektive styrker og svagheder samt muligheder for at blive tænkt sammen.
Hypotesen er, at Professionsfaglig forskning (i ernæring og sundhed) kan profitere af at tænke integralt, da
det øger graden af meningsfuld uenighed
Metoder
Med afsæt i Ken Wilbers og David R. Buchanans overvejelser, vil oplægget tegne et teoretisk landkort over
sundhedsvidenskabelige evidensformer.
(Foreløbige) resultater
På Ernærings- og Sundhedsuddannelserne arbejdes der i stigende grad med tværfagligt informeret ’integralperspektivistisk evidensmodel’, hvilket oplægsholderen bl.a. har omsat til ’kvadranten over rigtige måltider’.
Denne model er desuden under implementering i projektet ’kulinariske serveringskort’, der har Ruderdal
Kommune og Holbæk Sygehus som praksispartnere.
Konklusioner
De sundhedsvidenskabelige evidensformer må – særligt i en professionsfaglig sammenhæng – sorteres,
skærpes og integreres, så mulighederne for tværfaglig dialog og ’meningsfuld uenighed’ fremmes. Herved
øges kvaliteten af det tværfaglige samarbejde til gavn for borgeren.
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59. The Consumption of Enery Drinks Amongst 14-17 Year Old Danish Adolescents: An Examination of the Top Two Brands Consumed by this Target Group. Maria Juul Nielsen,
stud.cand.scient.san.publ, Graduate from Bachelor's Degree in Global Nutrition and Health
Partner University/ Collaboration Partner
 DTU Food
Background, aim and relevance
Examining the prevalence of energy drink (ED) consumption amongst 14-17-year-old Danish adolescents and
determine the top two brands consumed. Furthermore, investigating whether acute consumption of ED pose a
risk of exceeding maximum recommended intake (MRI) for caffeine and recommended daily intake (RDI) for
vitamins B6 and B12 for 14-17-year-olds when dietary intake is considered.
Methods
Findings are based on data from the descriptive cross-sectional study; ‘Consumption of energy drinks among
10-35-y-old Danes’ conducted by DTU Food. Through a web-based Food Frequency Questionnaire (FFQ),
respondents were required to register all alcoholic/non-alcoholic beverages and chocolates consumed within
the recent month. Descriptive statistics were used to describe overall prevalence of consumption. Nutrient
profiling of the top two ED were applied to three different defined consumer groups using cut-point-measures
of 250 ml, 500 ml and 1000 ml.
(Preliminary) Results
Prevalence of ED consumption amongst 14-17-year-old Danish adolescent was 34% (n=259) within the recent month, with Red Bull™ (27%, n=141) being the number one priority brand followed by Monster™ (11%,
n=56). Based on defined consumer groups findings suggest that acute consumption of ED pose a risk of exceeding both MRI for caffeine and RDI for vitamins B6 and B12.
Conclusions
Despite findings, it is concluded that the content of vitamins B6 and B12 in ED is not a concern, nor are related adverse health effects. However, further research is needed. Based on findings, and due to the well-known
adverse health effects of caffeine, focus should remain on this substance for future public health policy
initiatives. Front-of-package labeling was proposed as a primary prevention strategy to potentially limit sales
and thereby reduce consumption of ED amongst 14-17-year-olds. However, no studies have yet examined to
what extent FOP labels have an effect on the consumer decision-making process in adolescents. Mandatory
regulations imposed by the government should be considered.
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Institut for Sundhedsfaglig og Teknologisk Efter- og Videreuddannelse
60. Hvordan oplever førstegangsforældre at deltage i forældreuddannelse? Og hvilken betydning har sundhedsplejersken i forhold til at øge forældrenes handlekompetence? Julie
Ingvardsen, Sundhedsplejerske, Sygeplejerske.
Baggrund, formål og relevans
Forældreuddannelses formål er at styrke tilknytningen og det positive samspil mellem børn og forældre og lære forældrene at fremme deres barns sunde udvikling samt at mindske ulighed i sundhed på
længere sigt. I Danmark inspireres man af de svenske erfaringer med familieuddannelse og deres
gode socioøkonomiske resultater. Et større antal
kommuner herhjemme har indført forældreuddannelse som en del af sundhedsplejens tilbud. Disse
tilbud er i begrænset omfang blevet evalueret, og
der findes sparsomt dansk forskning på området
omkring forebyggelseseffekten, og hvorvidt forløbene er medvirkende til at øge forældres handlekompetence.
Metoder
Formålet med dette projekt er ud fra en interviewundersøgelse dels at beskrive forældrenes oplevelse af at
deltage i forældreuddannelse, og dels undersøge hvilke sundhedspædagogiske kompetencer sundhedsplejersken skal besidde for at indgå i forældreuddannelse. Undersøgelsen tager udgangspunkt i 3 kvalitative
interviews med forældrepar, der alle har deltaget i forældreuddannelsen "Familieiværksætterne".
(Foreløbige) resultater
Interviewundersøgelsen viste, at førstegangsforældre generelt har et stort udbytte af at deltage i forældreuddannelse. Mødre har et stort behov for en tryghedsskabende ramme, hvor de kan få bekræftelse, råd og hjælp
i rollen som mor, både fra sundhedsplejersken som ekspert, men også fra andre mødre i lignende situation.
Ydermere har mødrene gavn af at kombinere forældreuddannelse med deltagelse i en mødregruppe. Fædrene efterspurgte kønsopdelt undervisning med fokus på de bekymringer og holdninger, de har i forhold til at
være blevet far. Forældreuddannelse fordrer nogle behov for fornyet pædagogiske og didaktiske kompetencer
hos sundhedsplejersken, da hun skal facilitere flere forskelligartede læringsprocesser.
Konklusioner
Interviewundersøgelsen viste, at forældreuddannelse har en positiv effekt på forældreevnen hos både mor og
far. Såfremt forældreuddannelse skal implementeres som standartilbud i den kommunale sundhedspleje kræver det efteruddannelse af sundhedsplejersker samt løbende evaluering - og yderligere konceptudvikling af,
de forskellige forældreuddannelsesformer.
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Forskningsservice fra Biblioteket Metropol
61. Forskningsservice fra Biblioteket Metropol. Anna Møbjerg, informationsspecialist, Bente Larsen, informationsspecialist, Lene Kaad, informationsspecialist, Trine Azbi, afdelingsleder i biblioteket (kontaktperson).
Baggrund, formål og relevans
I forbindelse med Metropols strategi 2020 – Undervisere der forsker, oplever biblioteket en stigende interesse
og behov for særlige biblioteksservices rettet mod
forskningsunderstøttelse.
Biblioteket tilbyder derfor ansatte at få hjælp i deres
arbejdet med forskning- og udviklingsprojekter.
På dette års forskningsdag vil biblioteket præsentere
bibliotekets forskningsservice.
Metoder
En posterpræsentation der viser eksempler på bibliotekets service og de værktøjer der benyttes.
På posteren informeres om
 Brug af bibliotekets e-ressourcer i 2014 (opgørelse af artikeldownload, artikelbestillinger og brug af
databaser)
 Bibliotekssupport til ansattes FoU-aktiviteter (eksempler på projekter biblioteket har bidraget til)
 Studenterrapporter 2014 (opgørelse fra Studenterportalen og UC Viden)
 Metropol ansattes publicering og citering (opgørelse fra Web of Science (WoS) og Scopus)
 Ansattes videnproduktion 2014 (opgørelse fra UC Viden fordelt på typer, på autoritetslister mv.)
Der laves desuden flyers/bogmærker om Open Access (OA) og ORCID (forsker-ID)
(Foreløbige) resultater
Løbende udvikling og tilpasning af bibliotekets services, som regelmæssigt overensstemmes med de ansattes
behov. Foreløbig med positiv feedback fra brugere, der har kendskab til og benytter bibliotekets service.
Konklusioner
Biblioteket udbygger i øjeblikket forskningsservice for ansatte og er i gang med at implementere særlige services der understøtter hjælp til publicering, fondsansøgninger, citationsanalyser mm.
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