Zubsolv Rx data week 51
COMPANY ANALYSIS 29 December 2014
Summary
Orexo
(orx.st)
Zubsolv Rx data week 51
•
Buprenorphine/naloxone TRx volumes were up ahead
of the Christmas holiday, according to latest Wolters
Kluwer data. TRx increased t0 188,418, representing a
y/y growth of 8.4%. However, we do expect
significantly lower volumes in the coming weeks, as we
move in to the holiday season.
List:
Market Cap:
Industry:
CEO:
Chairman:
Mid cap
4,651 MSEK
Healthcare
Nikolaj Sörensen
Martin Nicklasson
OMXS 30
•
The rolling four weeks Zubsolv tablets market share
increased to 5.74% (up 0.06% from the week before).
Total number of Zubsolv tablets sold reached the new
record level of 324,621 for the week.
Orexo
200
180
160
140
120
•
Zubsolv recorded 10,028 scripts, and a market share
of 5.32%. The rolling four weeks market share for
Zubsolv rose 0.05 percentage point to 5.24%.
100
80
30-Dec
30-Mar
28-Jun
26-Sep
Redeye Rating (0 – 10 points)
Management
Growth prospect
Ownership
7.0 points
7.5 points
Profitability
Financial strength
0.0 points
7.5 points
3.0 points
Key Financials
Revenue. MSEK
Growth
EBITDA
EBITDA margin
EBIT
EBIT margin
Pre-tax earnings
Net earnings
Net margin
2012
326
2013
430
2014E
582
2015E
843
2016E
1 491
63%
32%
36%
45%
77%
-60
-87
-29
97
493
-18%
-20%
-5%
11%
33%
-79
-140
-36
57
463
-24%
-33%
-6%
7%
31%
-88
-86
-153
-155
-65
-67
27
17
446
410
-26%
-36%
-11%
2%
28%
2012
Dividend/Share
EPS adj.
P/E adj.
EV/S
EV/EBITDA
2012
2013
0.00
-2.86
-17.3
4.2
-23.2
2013
2014E
0.00
-4.33
-37.9
12.9
-63.6
2014E
2015E
0.00
-1.79
-75.5
8.3
-168.8
2015E
2016E
2.00
0.46
295.9
5.7
49.7
2016E
3.58
11.05
12.3
3.0
9.1
Share information
Share price (SEK)
Number of shares (m)
Market Cap (MSEK)
Net debt (MSEK)
135.5
34.3
4,651
201
Free float (%)
Daily turnover (’000)
55 %
122
Analysts:
Klas Palin
klas.palin@redeye.se
Ulrik Trattner
ulrik.trattner@redeye.se
Important information: All information regarding limitation of liability and potential conflicts of interest can be found at the end of the report.
Redeye. Mäster Samuelsgatan 42. 10tr. Box 7141. 103 87 Stockholm. Tel +46 8-545 013 30. E-post: info@redeye.se
Orexo
Redeye Rating: Background and definitions
The aim of a Redeye Rating is to help investors identify high-quality companies with attractive valuation.
Company Qualities
The aim of Company Qualities is to provide a well-structured and clear profile of a company’s qualities (or
operating risk) – its chances of surviving and its potential for achieving long-term stable profit growth.
We categorize a company’s qualities on a ten-point scale based on five valuation keys; 1 – Management. 2 –
Ownership. 3 – Growth Outlook. 4 – Profitability and 5 – Financial Strength.
Each valuation key is assessed based a number of quantitative and qualitative key factors that are weighted
differently according to how important they are deemed to be. Each key factor is allocated a number of points
based on its rating. The assessment of each valuation key is based on the total number of points for these
individual factors. The rating scale ranges from 0 to +10 points.
The overall rating for each valuation key is indicated by the size of the bar shown in the chart. The relative size of
the bars therefore reflects the rating distribution between the different valuation keys.
Management
Our Management rating represents an assessment of the ability of the board of directors and management to
manage the company in the best interests of the shareholders. A good board and management can make a
mediocre business concept profitable. while a poor board and management can even lead a strong company into
crisis. The factors used to assess a company’s management are: 1 – Execution. 2 – Capital allocation. 3 –
Communication. 4 – Experience. 5 – Leadership and 6 – Integrity.
Ownership
Our Ownership rating represents an assessment of the ownership exercised for longer-term value creation. Owner
commitment and expertise are key to a company’s stability and the board’s ability to take action. Companies with
a dispersed ownership structure without a clear controlling shareholder have historically performed worse than
the market index over time. The factors used to assess Ownership are: 1 – Ownership structure. 2 – Owner
commitment. 3 – Institutional ownership. 4 – Abuse of power. 5 – Reputation. and 6 – Financial sustainability.
Growth Outlook
Our Growth Outlook rating represents an assessment of a company’s potential to achieve long-term stable profit
growth. Over the long-term. the share price roughly mirrors the company’s earnings trend. A company that does
not grow may be a good short-term investment. but is usually unwise in the long term. The factors used to
assess Growth Outlook are: 1 – Strategies and business model. 2 – Sale potential. 3 – Market growth. 4 – Market
position. and 5 – Competitiveness.
Profitability
Our Profitability rating represents an assessment of how effective a company has historically utilised its capital to
generate profit. Companies cannot survive if they are not profitable. The assessment of how profitable a company
has been is based on a number of key ratios and criteria over a period of up to the past five years: 1 – Return on
total assets (ROA). 2 – Return on equity (ROE). 3 – Net profit margin. 4 – Free cash flow. and 5 – Operating
profit margin or EBIT.
Financial Strength
Our Financial Strength rating represents an assessment of a company’s ability to pay in the short and long term.
The core of a company’s financial strength is its balance sheet and cash flow. Even the greatest potential is of no
benefit unless the balance sheet can cope with funding growth. The assessment of a company’s financial strength
is based on a number of key ratios and criteria: 1 – Times-interest-coverage ratio. 2 – Debt-to-equity ratio. 3 –
Quick ratio. 4 – Current ratio. 5 – Sales turnover. 6 – Capital needs. 7 – Cyclicality. and 8 – Forthcoming binary
events.
Company analysis
2
Orexo
Weekly Rx data Zubsolv
Four-week rolling average, Zubsolv market share and tablet sales 2014
Source: Wolters Kluwer
Zubsolv market share
Rolling four weeks average - Zubsolv
•
During week 51 Zubsolv showed a w/w increase of
218 scripts, reaching a total of 10,028. This
represents a market share of 5.32%.
•
The rolling four weeks Zubsolv tablets market
share rose to 5.74%. The number of sold tablets
reaching almost 300,000 during the week.
•
Zubsolv tablets market share were 5.89%, down
0.03% from the week before
•
Rolling four weeks Zubsolv TRx reached 5.24%, an
increase of 0.05%.
•
Bunavail launch continues to underperform last
years launch of Zubsolv
Rolling four weeks average TRx market share and tablet sales
Suboxone
75,57%
12-19-14
75,67%
12-12-14
75,80%
12-05-14
75,92%
11-28-14
76,19%
11-21-14
76,45%
11-14-14
76,78%
11-07-14
77,02%
10-31-14
77,12%
10-24-14
77,20%
10-17-14
77,27%
10-10-14
77,38%
10-03-14
77,50%
09-26-14
77,62%
09-19-14
77,70%
09-12-14
77,74%
09-05-14
77,93%
08-29-14
77,97%
08-22-14
78,05%
08-15-14
78,13%
08-08-14
78,09%
08-01-14
78,31%
07-25-14
78,52%
07-18-14
78,79%
07-11-14
79,02%
07-04-14
Source: Wolters Kluwer
Generics
18,93%
18,93%
18,91%
18,89%
18,99%
19,10%
19,15%
19,26%
19,19%
19,14%
19,11%
19,05%
18,98%
18,90%
18,83%
18,80%
18,63%
18,62%
18,61%
18,56%
18,65%
18,58%
18,56%
18,52%
18,49%
Zubsolv
5,24%
5,19%
5,13%
5,08%
4,75%
4,42%
4,07%
3,71%
3,69%
3,66%
3,62%
3,57%
3,53%
3,48%
3,46%
3,46%
3,45%
3,40%
3,34%
3,31%
3,25%
3,11%
2,92%
2,69%
2,49%
Bunavail
0,26%
0,21%
0,16%
0,11%
0,06%
0,03%
0,01%
0,00%
0,00%
0,00%
0,00%
0,00%
0,00%
0,00%
0,00%
0,00%
0,00%
0,00%
0,00%
0,00%
0,00%
0,00%
0,00%
0,00%
0,00%
Company analysis
3
Suboxone
73,12%
73,20%
73,28%
73,37%
73,57%
73,85%
74,21%
74,48%
74,64%
74,69%
74,73%
74,85%
74,98%
75,07%
75,20%
75,21%
75,36%
75,40%
75,40%
75,44%
75,43%
75,72%
76,01%
76,42%
76,75%
Generics
20,93%
20,94%
20,99%
21,00%
21,12%
21,21%
21,24%
21,33%
21,24%
21,22%
21,20%
21,11%
21,01%
20,96%
20,87%
20,90%
20,75%
20,75%
20,81%
20,83%
20,96%
20,92%
20,94%
20,85%
20,81%
Zubsolv Bunavail
5,74%
0,21%
5,68%
0,18%
5,60%
0,14%
5,53%
0,10%
5,26%
0,06%
4,91%
0,03%
4,54%
0,01%
4,18%
0,00%
4,11%
0,00%
4,08%
0,00%
4,07%
0,00%
4,05%
0,00%
4,01%
0,00%
3,96%
0,00%
3,93%
0,00%
3,89%
0,00%
3,89%
0,00%
3,85%
0,00%
3,79%
0,00%
3,73%
0,00%
3,62%
0,00%
3,36%
0,00%
3,05%
0,00%
2,73%
0,00%
2,45%
0,00%
Orexo
Tablet sales H2 2014 buprenorphine/naloxone products
12-19-14
12-12-14
12-05-14
11-28-14
11-21-14
11-14-14
11-07-14
10-31-14
10-24-14
10-17-14
10-10-14
10-03-14
09-26-14
09-19-14
09-12-14
09-05-14
08-29-14
08-22-14
08-15-14
08-08-14
08-01-14
07-25-14
07-18-14
07-11-14
07-04-14
Suboxone
4014318
3842417
4102404
3333525
3829847
3733165
3928420
3652991
3762294
3794982
3872482
3844991
3769049
3749894
3841375
3621365
3854946
3727597
3734568
3762243
3787240
3721519
3759624
3783316
3834739
Generics
1159086
1088962
1165506
963661
1104041
1063234
1112807
1067368
1087390
1065289
1100473
1094257
1081949
1046036
1066023
1004171
1090615
1014280
1043144
1004865
1069110
1023877
1052053
1036623
1058026
Zubsolv
324621
311174
316007
248194
296045
285442
287780
212518
217219
208577
208853
207214
210847
201961
202040
186494
205257
192350
188710
192393
193814
178568
178093
171110
142218
Bunavail
14928
12899
9243
7515
6797
4303
651
60
178
506
180
30
Total
5512953
5255452
5593160
4552895
5236730
5086144
5329658
4932937
5067081
5069354
5181988
5146492
5061845
4997891
5109438
4812030
5150818
4934227
4966422
4959501
5050164
4923964
4989770
4991049
5034983
Source: Wolters Kluwer
Scripts H2 2014 buprenorphine/naloxone products
12-19-14
12-12-14
12-05-14
11-28-14
11-21-14
11-14-14
11-07-14
10-31-14
10-24-14
10-17-14
10-10-14
10-03-14
09-26-14
09-19-14
09-12-14
09-05-14
08-29-14
08-22-14
08-15-14
08-08-14
08-01-14
07-25-14
07-18-14
07-11-14
07-04-14
Suboxone
142097
137372
144691
123039
138921
136026
141268
136116
138252
139094
139929
140697
139095
138098
140254
133371
141457
137307
137765
137639
139077
137454
138787
139245
136415
Generics
35664
34477
36101
30795
34715
33741
34886
34328
34875
34295
34903
34765
34548
33766
34363
32214
34383
32936
33465
31681
33706
32712
33271
32782
32210
Source: Wolters Kluwer
Company analysis
4
Zubsolv
10028
9806
9933
8194
9384
9220
9298
6559
6827
6698
6593
6601
6619
6289
6245
5904
6377
6102
6082
5961
5927
5656
5877
5642
4752
Bunavail
629
545
389
303
268
173
26
2
5
10
6
1
Total
188418
182200
191114
162331
183288
179160
185478
177005
179959
180097
181431
182064
180262
178153
180862
171489
182217
176345
177312
175281
178710
175822
177935
177669
173377
Orexo
Summary Redeye Rating
The rating consists of five valuation keys. each constituting an overall
assessment of several factors that are rated on a scale of 0 to 2 points. The
maximum score for a valuation key is 10 points.
Management 7.5p
The management and board have solid, relevant experience of the sector.
Communication with the market is good and clear. The launch of Zubsolv
is lagging slightly behind the original plan.
Ownership 7.0p
Orexo’s major shareholders are represented and active on the board,
which is a big plus. However, we would prefer to see ownership among all
of the board, which would bolster the rating.
Growth prospect 7.5p
Growth over the next few years is governed by the success of the recently
launched Zubsolv on the US market. The drug has great commercial
potential and sales are expected to grow strongly over the next few years.
Risk maintains relatively high as the product is not yet established.
Profitability 0.0p
The company’s flagship product Zubsolv is in establishment phase and it
will take until next year before Orexo achieves profitability.
Financial strength 3.0p
The financial position has improved due to issues and current financing
is deemed adequate until positive cash flow can be achieved.
Company analysis
5
Orexo
Income statement
Net sales
Total operating costs
EBITDA
2012
326
-386
-60
2013
430
-517
-87
2014E
582
-611
-29
2015E
843
-746
97
2016E
1 491
-998
493
Depreciation
Amortization
Impairment charges
EBIT
-7
-13
0
-79
-7
-46
0
-140
-6
-2
0
-36
-3
-37
0
57
-3
-27
0
463
Share in profits
Net financial items
Exchange rate dif.
Pre-tax profit
0
-8
0
-88
0
-14
0
-153
0
-28
0
-65
0
-29
0
27
0
-17
0
446
Tax
Net earnings
2
-86
-2
-155
-2
-67
-10
17
-36
410
2012
2013
2014E
2015E
2016E
228
37
28
0
293
106
55
383
0
544
296
116
495
0
908
348
126
489
0
963
670
194
552
0
1 415
35
19
0
26
106
3
0
189
0
33
0
0
26
62
106
0
228
0
31
0
0
26
62
185
0
304
0
33
0
0
28
62
133
0
256
0
36
0
0
30
62
106
0
235
0
482
772
1 212
1 220
1 650
Balance
Assets
Current assets
Cash in banks
Receivables
Inventories
Other current assets
Current assets
Fixed assets
Tangible assets
Associated comp.
Investments
Goodwill
Cap. exp. for dev.
O intangible rights
O non-current assets
Total fixed assets
Deferred tax assets
Total (assets)
Liabilities
Current liabilities
Short-term debt
Accounts payable
O current liabilities
Current liabilities
Long-term debt
O long-term liabilities
Convertibles
Total Liabilities
Deferred tax liab
Provisions
Shareholders' equity
Minority interest (BS)
Minority & equity
11
158
0
169
10
4
103
287
0
4
191
0
191
237
360
0
597
4
0
0
601
10
0
162
0
162
3
262
0
265
494
0
0
759
8
0
445
0
445
3
253
0
256
494
0
0
750
8
0
462
0
462
3
343
0
346
494
0
0
840
7
0
803
0
803
Total liab & SE
482
772
1 212
1 220
1 650
Free cash flow
Net sales
Total operating
costs
Depreciations total
EBIT
Taxes on EBIT
NOPLAT
Depreciation
Gross cash flow
Change in WC
Gross CAPEX
2012
326
-386
2013
430
-517
2014E
582
-611
2015E
843
-746
2016E
1 491
-998
-20
-79
2
-78
20
-58
90
0
-53
-140
-1
-141
53
-88
-201
-111
-7
-36
-1
-37
7
-30
-271
-84
-40
57
-13
44
40
84
-13
8
-30
463
-37
426
30
456
-40
-9
32
-400
-385
79
406
Capital structure
Equity ratio
Debt/equity ratio
Net debt
Capital employed
Capital turnover
rate
2012
40%
65%
-103
69
0.7
2013
21%
149%
135
297
0.6
2014E
37%
112%
201
645
0.5
2015E
38%
108%
149
611
0.7
2016E
49%
62%
-173
631
0.9
Growth
Sales growth
EPS growth (adj)
2012
63%
-78%
2013
32%
64%
2014E
36%
-59%
2015E
45%
-126%
2016E
77%
2 313%
Free cash flow
DCF valuation
WACC (%)
13.4 %
Cash flow. MSEK
Assumptions 20152021 (%)
Average sales growth
EBIT margin
7.1 %
39.9 %
Fair value e. per share. SEK
Share price. SEK
162.3
135.5
Profitability
ROE
ROCE
ROIC
EBITDA margin
EBIT margin
Net margin
2012
-34%
-21%
-42%
-18%
-24%
-26%
2013
-88%
-39%
-204%
-20%
-33%
-36%
2014E
-22%
-10%
-13%
-5%
-6%
-11%
2015E
4%
3%
7%
11%
7%
2%
2016E
65%
39%
70%
33%
31%
28%
Data per share
EPS
EPS adj
Dividend
Net debt
Total shares
2012
-2.86
-2.86
0.00
-3.45
30.00
2013
-4.70
-4.33
0.00
4.11
32.97
2014E
-1.94
-1.79
0.00
5.84
34.33
2015E
0.50
0.46
2.00
4.33
34.33
2016E
11.95
11.05
3.58
-5.03
34.33
2012
1 384.6
-17.3
-17.3
4.6
4.2
-23.2
-17.4
7.8
2013
5 542.5
-34.9
-37.9
12.6
12.9
-63.6
-39.7
33.5
2014E
4 851.6
-69.8
-75.5
8.0
8.3
-168.8
-133.9
10.5
2015E
4 799.6
273.6
295.9
5.5
5.7
49.7
84.9
10.1
2016E
4 478.5
11.3
12.3
3.1
3.0
9.1
9.7
5.8
Valuation
EV
P/E
P/E diluted
P/Sales
EV/Sales
EV/EBITDA
EV/EBIT
P/BV
Share performance
1 month
3 month
12 month
Since start of the year
-0.7
5.0
-15.6
-17.4
Shareholder structure %
Novo Nordisk Fonden
HealthCap
ATP
SHB fonder
Anders Walldow
Avanza Pension Försäkring
Andra AP-fonden
Hans Sköld
Thomas Lundqvist
Länsförsäkringar fondförvaltning
%
%
%
%
Growth/year
Net sales
Operating profit adj
EPS. just
Equity
12/14e
33.6 %
-32.5 %
-20.8 %
52.6 %
Capital
28.1 %
11.7 %
5.4 %
4.9 %
3.4 %
2.9 %
2.2 %
1.8 %
1.4 %
1.4 %
Votes
28.1 %
11.7 %
5.4 %
4.9 %
3.4 %
2.9 %
2.2 %
1.8 %
1.4 %
1.4 %
Share information
Reuters code
List
Share price
Total shares. million
Market Cap. MSEK
orx.st
Mid cap
135.5
34.3
4651.0
Management & board
CEO
CFO
IR
Chairman
Nikolaj Sörensen
Henrik Juuel
Henrik Juuel
Martin Nicklasson
Financial information
FY 2014 Results
Q1 report
Q2 report
Q3 report
January
April
July
October
Analysts
Klas Palin
klas.palin@redeye.se
Ulrik Trattner
ulrik.trattner@redeye.se
Company analysis
6
29.
23.
10.
22.
2015
2015
2015
2015
Redeye AB
Mäster Samuelsgatan 42. 10tr
111 57 Stockholm
Orexo
Revenue & Growth (%)
EBIT (adjusted) & Margin (%)
1600
600
500
400
300
200
100
0
-100
-200
-300
-400
-500
90,0%
80,0%
70,0%
60,0%
50,0%
40,0%
30,0%
20,0%
10,0%
0,0%
-10,0%
1400
1200
1000
800
600
400
200
0
2011
2012
2013
2014E
Net sales
2015E
2016E
0,0%
-50,0%
-100,0%
2011
2012
2013
2014E
2015E
2016E
-150,0%
-200,0%
-250,0%
Net sales growth
EBIT adj
Earnings per share
EBIT margin
Equity & debt-equity ratio (%)
15
15
0,6
10
10
0,5
5
5
0
0
2011
50,0%
2012
2013
2014E
2015E
2016E
-5
-5
-10
-10
160,0%
140,0%
120,0%
0,4
100,0%
0,3
80,0%
60,0%
0,2
40,0%
0,1
20,0%
0
-15
-15
EPS, unadjusted
EPS, adjusted
0,0%
2011
2012
2013
Equity ratio
Conflict of interests
Klas Palin owns shares in the company: No
Ulrik Trattner owns shares in the company: No
Redeye performs/have performed services for the Company and
receives/have received compensation from the Company in connection
with this.
Company analysis
7
2014E
2015E
2016E
Debt-equity ratio
Orexo
DISCLAIMER
Important information
Redeye AB ("Redeye" or "the Company") is a specialist financial advisory ooutique that focuses on small and mid-cap growth companies in the Nordic
region. We focus on the technology and life science sectors. We provide services within Corporate Broking. Corporate Finance. equity research and
investor relations. Our strengths are our award-winning research department. experienced advisers. a unique investor network. and the powerful
distribution channel redeye.se. Redeye was founded in 1999 and since 2007 has been subject to the supervision of the Swedish Financial Supervisory
Authority.
Redeye is licensed to; receive and transmit orders in financial instruments. provide investment advice to clients regarding financial instruments. prepare
and disseminate financial analyses/recommendations for trading in financial instruments. execute orders in financial instruments on behalf of clients.
place financial instruments without position taking. provide for the safekeeping of financial instruments. accept funds with accounting responsibility.
provide corporate advice and services within mergers and acquisition. provide services in conjunction with the provision of guarantees regarding financial
instruments and to operate as a Certified Advisory business (ancillary authorization).
Limitation of liability
This document was prepared for information purposes for general distribution and is not intended to be advisory. The information contained in this
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information in the analysis is based on subjective assessments about the future. which constitutes a factor of uncertainty. Redeye cannot guarantee that
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•
For companies that are the subject of Redeye’s research analysis. the applicable rules include those established by the Swedish Financial
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•
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Redeye does not issue any investment recommendations for fundamental analysis. However. Redeye has developed a proprietary analysis and rating
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question. its opportunities. risks. etc. The purpose is to provide an objective and professional set of data for owners and investors to use in their decisionmaking.
Redeye Rating (2014-12-30)
Rating
7.5p - 10.0p
3.5p - 7.0p
0.0p - 3.0p
Company N
Management
Ownership
22
50
1
73
30
38
5
73
Growth
Prospect
11
61
1
73
Profitability
7
30
36
73
Financial
Strength
16
31
26
73
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Copyright Redeye AB.
Company analysis
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