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Research Seminar
Exosomes and Microvesicles
Time and Place
th
Monday 5 of May 2014, at 9—12.
Auditoriet
Forskningens Hus
Søndre Skovvej 15, 9000 Aalborg
Research seminar with special guest lecturer
Prof. Richard Simpson
(Melbourne, Australien)
Programme
9.00
Introduction by Allan Stensballe (AAU) and
Malene Jørgensen (AUH)
9.15
Plenary lecture by Richard Simpson
”Exosomes: proteomic insights and diagnostic
potential”
10.15
Coffee break with refreshments
10.30
Allan Stensballe (AAU)
”Mass spectrometry driven profiling of
extracellular microvesicles in health & disease”
10.45
Malene Jørgensen (AUH)
Richard Simpson
Richard Simpson is a professor at the Department of Biochemistry at La Trobe University (Melbourne, Australia).
Richard Simpson is considered to be the key pioneer in the
development of isolation procedures and proteomics based
characterization of exosomes. His main focus is the functional investigation of exosomes derived from colon cancer and
their influence in cellular communication.
He is the inaugural and current president of the Australasian
Proteomics Society and a past treasurer of the Human Proteome Organization. Richard Simpson was elected Honorary
Member of the American Society of Biochemistry and Molecular Biology in 1996, awarded the AMRAD Pharmacia
Medal from the Australian Society for Biochemistry & Molecular Biology, and was an elected councilor of the Protein
Society (1993-1996).
Most recent publications:

”EV Array - problems and possibilities”
11.00
Søren Risom Kristensen (AUH)

”Exosomes and their involvement in the
coagulation processes”
11.15
Aase Handberg/ Morten Hjuler (AUH)
”Characterization of microparticles by flow
cytometry”
11.30
Anne Louise Revenfeld (AAU/AUH)
”Extracellular vesicles from mono- and cocultures of human dendritic cells and CD4+
T-cells ”
12.00

Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma. Proteomics
2013.
Oncogenic H-ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Mol Cell Proteomics
2013.
Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal
transduction components. Proteomics 2013.
Pablo Pennisi (AAU)
”Stem cell derived exosomes and their possiblities
in regenerative medicine”
11.45

Detection of cadherin-17 in human colon cancer LIM1215 cell secretome and tumour
xenograft-derived interstitial fluid and plasma. Biochim Biophys Acta 2013.
Final remarks by Allan Stensballe (AAU)
Contact information
Allan Stensballe
Associate Professor
Laboratory for Medical Mass
Spectrometry
Malene Jørgensen
Senior Scientist
Department of Clinical
Immunology
Aalborg University
Aalborg University Hospital
as@hst.aau.dk
maljoe@rn.dk