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R. Scott Rector
3/23/15
Curriculum Vitae
Randy Scott Rector, Ph.D.
Office Address:
Internal Medicine-Division of Gastroenterology
CE405 Clinical Support Education Building
University of Missouri-Columbia
&
Harry S Truman Memorial VA Hospital
B015 VA Research
Columbia, MO 65201
Phone (573) 814-6000 ext 53779
Fax (573) 884-4595
E-mail: rectors@health.missouri.edu
EDUCATION/TRAINING
Date
Institution
Aug 1998
Arkansas State University, Jonesboro, AR
Mentors: Dr. Jake Darby and Dr. Jack Sugg
Aug 1999
Arkansas State University, Jonesboro, AR
Mentor: Dr. Mike Greenwood
May 2007
University of Missouri, Columbia, MO
Mentor: Dr. Tom R. Thomas
July 2010
University of Missouri, Columbia, MO
Mentor: Dr. Jamal A. Ibdah
Degree
BS
Discipline
Exercise Science
MS
Exercise Science
PhD
Exercise Physiology
Post-Doc
Hepatology
PROFESSIONAL EXPERIENCE AND ACADEMIC APPOINTMENTS
1998
Internship in Cardiac Rehab at St. Bernards Medical Center, Jonesboro, AR
1998-1999
Graduate Teaching Assistant, Arkansas State University
1999-2001
Adjunct Faculty, Arkansas State University
2001-2007
Graduate Research Assistant, University of Missouri-Columbia
2007-2010
Post-Doctoral Research Fellow, Internal Medicine, Division of Gastroenterology
and Hepatology, University of Missouri-Columbia
2004-2011
Harry S Truman Memorial Veterans Medical Center, Research Service, Biological Research
Technician-WOC
July 2010Assistant Professor, Medicine-Division of Gastroenterology and Hepatology, and Nutrition
and Exercise Physiology, University of Missouri
July 2011Research Health Scientist, Harry S Truman Memorial Veterans Medical Center, Research
Service
RESEARCH
Peer Reviewed Publications
1. TR Thomas, J Pellechia, RS Rector, GY Sun, MS Sturek, and MH Laughlin. Exercise training does not
reduce hyperlipidemia in pigs fed a high-fat diet. Metabolism 12:1587-1595, 2002.
2.
KK Henderson, EA Mokelke, JR Turk, RS Rector, MH Laughlin, and M Sturek. Maintaining vascular
access port patency and asepsis in Yucatan miniature swine. Contemp. Topics Lab. Anim. Sci. 42(6):1620, 2003.
3.
Y Liu, RS Rector, TR Thomas, JA Taylor, DA Holiman, KK Henderson, WV Welshons, and MS Sturek.
Lipoproteins during the estrous cycle in swine. Metabolism 53(2):140-141, 2003.
4.
R. Scott Rector
2
RS Rector, TR Thomas, Y Liu, KK Henderson, DA Holiman, and M Sturek. Effect of exercise on
postprandial lipemia following a higher calorie meal in Yucatan miniature swine. Metabolism 53(8): 10211026, 2004.
5.
PS Hinton, RS Rector, JE Peppers, RD Imhoff, and LS Hillman. Serum markers of inflammation and
endothelial function are elevated by hormonal contraceptive use, but not by exercise-associated menstrual
disorders in physically active young women. J of Sports Science and Medicine 5: 235-242, 2006.
6.
JP Thyfault, RS Rector, and RC Noland. Metabolic inflexibility in skeletal muscle: a prelude to the
CardioMetabolic Syndrome? J of the CardioMetabolic Syndrome 1:184-189, 2006.
7.
RS Rector, JR Turk, GY Sun, BL Guilford, BW Toedebusch, MW McClanahan, and TR Thomas. Shortterm lifestyle modification alters circulating biomarkers of endothelial health in sedentary, overweight
adults. Appl. Physiol. Nutr. Metab. 31(5): 512–517, 2006. PMID: 17111005
8.
PS Hinton, RS Rector, and TR Thomas. Weight-bearing, aerobic exercise increases markers of bone
formation during short-term weight loss in overweight and obese men and women. Metabolism. 55:16161618, 2006.
9.
TR Thomas, Y Liu, MA Linden, and RS Rector. Interaction of Exercise Training and n-3 Fatty Acid
Supplementation on Postprandial Lipemia. Appl. Physiol. Nutr. Metab. 32:473-480, 2007.
10. RS Rector, SO Warner, Y Liu, PS Hinton, GY Sun, RH Cox, CS Stump, MH Laughlin, KC Dellsperger,
and TR Thomas. Exercise and diet induced weight loss improves measures of oxidative stress and insulin
sensitivity in adults with characteristics of the metabolic syndrome. Am J Physiol Endocrinol Metab.
293(2):E500-6, 2007.
11. RS Rector, R Rogers, M Ruebel, and PS Hinton. Participation in road cycling vs running is associated
with lower bone mineral density in men. Metabolism. 57:226–232, 2008.
12. RS Rector, JP Thyfault, Y Wei, and JA Ibdah. Non-Alcoholic Fatty Liver Disease and the Metabolic
Syndrome: An Update. World J. Gastro. 14(2):185-92, 2008.
13. Y Wei, RS Rector, JP Thyfault, JA Ibdah. Nonalcoholic fatty liver disease and mitochondrial dysfunction.
World J. Gastro. 14(2):193-9, 2008.
14. RS Rector, JP Thyfault, RT Morris, MJ Laye, SJ Borengasser, FW Booth, and JA Ibdah. Daily exercise
increases hepatic fatty acid oxidation and prevents steatosis in Otsuka Long-Evans Tokushima Fatty
(OLETF) rats. Am J Physiol Gastro 294(3):G619-26, 2008. PMID: 18174272
15. FW Booth, MJ Laye, SJ Lees, RS Rector, and JP Thyfault. Reduced physical activity and risk of chronic
disease: the biology behind the consequences. Eur J of Applied Phys 102(4):381-90, 2008.
16. RT Morris, MJ Laye, MH Laughlin, SJ Lees, RS Rector, JP Thyfault, FW Booth. Exercise-induced
prevention of obesity and hyperinsulinemia in the OLETF rat is associated with reduced skeletal muscle
lipid peroxidation. J Appl Physiol 104(3):708-15, 2008.
17. RS Rector, JP Thyfault, MJ Laye, RT Morris, SJ Borengasser, GM Uptergrove, FW Booth, and JA Ibdah.
Cessation of daily exercise dramatically alters precursors of hepatic steatosis in Otsuka Long-Evans
Tokushima Fatty (OLETF) rats. J Physiol. 586(17):4241-9, 2008.
18. RS Rector, RM Payne, and JA Ibdah. Mitochondrial Trifunctional Protein Defects: Clinical Implications
and Therapeutic Approaches. Advanced Drug Delivery Reviews. 60(13-14):1488-96, 2008.
R. Scott Rector
19. RS Rector, R Rogers, M Ruebel, MO Widzer, and PS Hinton. Lean body mass and weight-bearing
activity in the prediction of bone mineral density in physically active males. J Strength Cond Res.
23(2):427-35, 2009.
3
20. MJ Laye, RS Rector, SJ Borengasser, SP Naples, GM Uptergrove, JA Ibdah, FW Booth, and JT Thyfault.
Cessation of daily wheel running differentially alters fat oxidation capacity in liver, muscle, and adipose
tissue. J Appl Physiol 106(1): 161-8, 2009.
21. RS Rector and JA Ibdah. Negative consequences of physical inactivity on non-alcoholic fatty liver
disease development. Phys News. No 74, Spring 2009. -Invited
22. JP Thyfault, RS Rector, GM Uptergrove, SJ Borengasser, EM Morris, Y Wei, MJ Laye, SE Ridenhour, LG
Koch, SL Britton, and JA Ibdah. Rats selectively bred for low endurance capacity develop nonalcoholic
fatty liver disease. J Physiol. 587(8):1805-16, 2009. PMID: 19237421
23. MJ Laye, RS Rector, SO Warner, SP Naples, AL Perretta, GM Uptergrove, MH Laughlin, JP Thyfault, FW
Booth, and JA. Ibdah. Changes in visceral adipose tissue mitochondrial content with type 2 diabetes and
daily voluntary wheel running in OLETF rats. J Physiol. 587(14):3729-39, 2009. PMID: 19491243
24. JP Thyfault and RS Rector. Linking aerobic fitness, nonalcoholic fatty liver disease and the metabolic
syndrome. Expert Rev. Endocrinol. Metab. 4(4): 299-301, 2009.
25. RS Rector, J Loethen, M Ruebel, TR Thomas, and PS Hinton. Serum markers of bone turnover are
increased by moderate weight loss with or without weight-bearing exercise in overweight premenopausal
women. Appl. Physiol. Nutr. Metab. 34:933-941, 2009.
26. RS Rector, MA Linden, SO Warner, Y Liu, TS Altena, BK Smith, JQ Zhang, GG Ziogas, and TR Thomas.
Predicting postprandial lipemia in healthy adults and in at risk individuals with components of the
cardiometabolic syndrome. J of Clinical Hypertens 11(11):663-71, 2009.
27. PS Hinton, JD LeCheminant, BK Smith, RS Rector, and JE Donnelly. Weight loss-induced alterations in
serum markers of bone turnover persist during weight maintenance in obese men and women. J Amer
College Nutr. 28(5):565-73, 2009. PMID: 20439552
28. RS Rector and JA Ibdah. Fatty acid oxidation disorders: maternal health and neonatal outcomes. Semin
Fetal Neonatal Med. 5(3):122-8, 2010.
29. PS Hinton, BK Smith, B Bailey, RS Rector, and JE Donnelly. Total body bone mineral content and
density during weight loss and maintenance on a low- or recommended-dairy weight maintenance diet in
obese men and women. European J Clin Nutr. 64(4):392-9, 2010.
30. RS Rector, JP Thyfault, GM Uptergrove, EM Morris, SP Naples, SJ Borengasser, CR Mikus, MJ Laye,
MH Laughlin, FW Booth, and JA Ibdah. Mitochondrial dysfunction precedes insulin resistance and hepatic
steatosis and contributes to the natural history of nonalcoholic fatty liver disease in an obese rodent
model. J of Hepatology. 52(5):727-36, 2010. PMID: 20347174
31. SP Naples, SJ Borengasser, RS Rector, GM Uptergrove, EM Morris, CR Mikus, LG Koch, SL Britton, JA
Ibdah, and JP Thyfault. Skeletal Muscle Mitochondrial and Metabolic Responses to a High Fat Diet in Rats
Bred for High and Low Aerobic Capacity. Appl. Physiol. Nutr. Metab. 35(2):151-62, 2010.
32. TR Thomas, SO Warner, KC Dellsperger, PS Hinton, AT Whaley-Connell, RS Rector, Y. Liu, MA Linden,
A Chockalingam, JP Thyfault, DR Huyette, Z Wang, and RH Cox. Exercise and the Metabolic Syndrome
with Weight Regain. J Appl Physiol. 109(1):3-10, 2010. PMID: 20167668
R. Scott Rector
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33. AK Bunker, AA Arce-Esquivel, RS Rector, FW Booth, JA Ibdah, and MH Laughlin. Physical activity
maintains aortic endothelium-dependent relaxation in the obese type 2 diabetic OLETF rat. Am J Physiol
Heart Circ Physiol. 298(6):H1889-901, 2010. PMID: 20304812
34. RS Rector, GM Uptergrove, SJ Borengasser, CR Mikus, EM Morris, SP Naples, MJ Laye, MH Laughlin,
FW Booth, JA Ibdah, and JP Thyfault. Changes in skeletal muscle mitochondria in response to the
development of type 2 diabetes or prevention by daily wheel running in hyperphagic OLETF rats. Am J
Physiol Endocrinol Metab. 298(6):E1179-87, 2010. PMID: 20233940
35. JP Thyfault and RS Rector. Exercise: not just a medicine for muscle? J Physiol. 588(15):2687-8, 2010.
PMID: 20675815.
36. CR Mikus, RS Rector, AA Arce, JL Libla, FW Booth, JA Ibdah, MH Laughlin, and JP Thyfault. Daily
physical activity enhances reactivity to insulin in skeletal muscle arterioles of hyperphagic Otsuka LongEvans Tokushima Fatty rats. J Appl Physiol. 109(4):1203-10, 2010. PMID 20634354.
37. RS Rector, GM Uptergrove, EM Morris, SJ Borengasser, MH Laughlin, FW Booth, JP Thyfault, and JA
Ibdah. Daily exercise vs. caloric restriction for prevention of nonalcoholic fatty liver disease in the OLETF
rat model. Am J Physiol Gastrointest Liver Physiol. 300(5):G874-83, 2011. PMID 21350190
38. EM Morris, RS Rector, JP Thyfault, and JA Ibdah. Mitochondria and Redox Signaling in Steatohepatitis.
Antioxidant Redox Signaling. 15(2):485-504, 2011. PMID:21128703
39. RS Rector and JP Thyfault. Does physical inactivity cause nonalcoholic fatty liver disease? J Appl
Physiol. 111(6):1828-35, 2011. PMID 21565984
40. SJ Borengasser, RS Rector, GM Uptergrove, EM Morris, JW Perfield, FW Booth, KL Fritsche, JA Ibdah
and JP Thyfault. Exercise and omega-3 polyunsaturated fatty acid supplementation for the treatment of
hepatic steatosis in hyperphagic OLETF rats. J of Nutr and Metab. 2012;2012:268680 PMID 21918718
41. PS Hinton, RS Rector, MA Linden, SO Warner, KC Dellsperger, A Chockalingam, AT Whaley-Connell, Y
Liu, and TR Thomas. Weight-loss-associated changes in bone mineral density and bone turnover persist
after partial weight regain with or without aerobic exercise in obese women. European J Clin Nutr 66(5):6606-612, 2012. PMID 22190134
42. PS Hinton, JP Thyfault, TR Thomas, BK Smith, JE Donnelly, RS Rector. Weight loss-induced increases
in osteocalcin: bone formation or glucose regulation? Endocrinol Metabol Syndrome 2011, S:1
doi.org/10.4172/2161-1017.S1-002
43. JA Fletcher, JW Perfield II, JP Thyfault, and RS Rector. The second meal effect and its influence on
glycemia. J of Nutrition Disorder & Ther. 2012, 2:108. doi:10.4172/jndt.1000108
44. EM Morris, JA Fletcher, JP Thyfault, RS Rector. The Role of Angiotensin II in Nonalcoholic
Steatohepatitis. Molecular and Cellular Endocrinology. 2012 May 11. PMID: 22579612.
45. JA Fletcher, GM Meers, MH Laughlin, JA Ibdah, JP Thyfault, and RS Rector. Modulating Fibroblast
Growth Factor-21 in Hyperphagic OLETF Rats with Daily Exercise and Caloric Restriction. Appl Physiol
Nutr Metabol. 37(6):1054-62, 2012. PMID: 22891896
46. CR Mikus, BT Roseguini, GM Meers, EM Morris, RS Rector, JL Libla, DJ Oberlin, SJ Borengasser, AM
Taylor, JA Ibdah, MH Laughlin, and JP Thyfault. Voluntary wheel running selectively augments insulinstimulated vasodilation in arterioles from white skeletal muscle of insulin resistant rats. Microcirculation.
19(8):729-38, 2012. PMID: 22804760
R. Scott Rector
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47. J Martin, J Padilla, N Jenkins, J Crissey, S Bender, RS Rector, JP Thyfault, and MH Laughlin. Functional
adaptations in the skeletal muscle microvasculature to endurance and interval sprint training in the type 2
diabetic OLETF rat. J Appl Physiol . 113(8): 1223-32, 2012. PMID: 22923508
48. NT Jenkins, J Padilla, AA Arce-Esquivel, DS Bayless, JS Martin, HJ Leidy, FW Booth, RS Rector, and
MH Laughlin. Effects of Endurance Exercise Training, Metformin, and their Combination on Adipose
Tissue Leptin and IL-10 Secretion in OLETF Rats. J Appl Physiol.113(12):1873-83, 2012. PMID
23019312
49. EA Dannecker, Y Liu, RS Rector, TR Thomas, RB Fillingim, and ME Robinson. Sex Differences in
Exercise-Induced Pain and Muscle Damage. J Pain. 13(12):1242-49, 2012. PMID: 23182229
50. LC Ortinau, RT Pickering, KJ Nickelson, KL Stromsdorfer, CY Naik, RA Haynes, DE Bauman, RS Rector,
KL Fritsche, JW Perfield II. Sterculic oil, a natural SCD1 inhibitor, improves glucose homeostasis in obese
ob/ob mice. ISRN Endocrinology. 2012:947323, 2012. PMID: 23209931
51. EA Dannecker, Y Liu, RS Rector, TR Thomas, SP Sayers, C Leeuwenburgh, BK Ray. The effects of
fasting on indicators of muscle damage. Experimental Gerontology. 48(10):1101-6, 2013. PMID:
23266375
52. JW Perfield II, LC Ortinau, RT Pickering, ML Ruebel, GM Meers, and RS Rector. Altered Hepatic Lipid
Metabolism Contributes to Nonalcoholic Fatty Liver Disease in Leptin-Deficient Ob/Ob Mice. J Obesity,
2013; 2013:296537. PMID: 23401753
53. RS Rector, EM Morris, S Ridenhour, GM Meers, FF Hsu, J Turk, and JA Ibdah. Selective hepatic insulin
resistance in mice heterozygous for a mitochondrial trifunctional protein defect. Hepatology. 57(6): 22132213, 2013. PMID: 23359250
54. MD Roberts, DS Bayless, TE Childs, NT Jenkins, J Padilla, JS Martin, LP Oberle, JM Company, VJ Dalbo,
FW Booth, RS Rector, MH Laughlin. Elevated skeletal muscle irisin precursor FNDC% mRNA in obese
OLETF rats. Metabolism 62(8):1052-6, 2013 PMID: 23498898
55. Padilla J, Jenkins NT, Lee S, Zhang H, Cui J, Zuidema MY, Zhang C, Hill MA, Perfield JW 2nd, Ibdah JA,
Booth FW, Davis JW, Laughlin MH, Rector RS. Vascular transcriptional alterations produced by juvenile
obesity in Ossabaw swine. Physiol Genomics. 45(11):434-46, 2013. PMID: 23592636
56. MA Linden, GM Meers, ML Ruebel, NT Jenkins, FW Booth, ML Laughlin, JA Ibdah, JP Thyfault, and RS
Rector. Hepatic Steatosis Development with Four Weeks of Physical Inactivity in Previously Active,
Hyperphagic OLETF Rats. Am J Physiol Regul Integr Comp Physiol. 304(9):R763-71, 2013 PMID:
23467323
57. DJ Oberlin, CR Mikus, ML Kearney, PS Hinton, C Manrique, HJ Leidy, JA Kanaley, RS Rector, JP
Thyfault. One Bout of Exercise Alters Free-Living Postprandial Glycemia in Type 2 Diabetes. Med Sci
Sports Exerc 46(2):232-8, 2014. PMID: 23872939
58. JM Crissey, J Padilla, NT Jenkins, JS Martin, RS Rector, JP Thyfault, and MH Laughlin. Metformin does
not enhance insulin-stimulated vasodilation in the skeletal muscle microvasculature of the insulin resistant,
type 2 diabetic OLETF rat. Microcirculation, 20(8):764-75, 2013 PMID: 23879830
59. NT Jenkins, J Padilla, RS Rector, and MH Laughlin. Influence of regular physical activity and caloric
restriction on β-adrenergic and natriuretic peptide receptor expression in retroperitoneal adipose tissue of
OLETF rats. Experimental Physiology, 98(11):1576-84, 2013 PMID: 23833052
R. Scott Rector
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60. NT Jenkins, J Padilla, JS Martin, JM Crissey, JP Thyfault, RS Rector, and MH Laughlin. Differential
vasomotor effects of insulin on gastrocnemius and soleus feed arteries in the OLETF rat model: Role of
endothelin-1. Experimental Physiology, 99(1):262-71, 2014. PMID: 23995100
61. Fletcher JA, Meers GM, Linden MA, Kearney ML, Morris EM, Thyfault JP, Rector RS. Impact of various
exercise modalities on hepatic mitochondrial function. Med Sci Sports Exerc. 46(6):1089-97, 2014 PMID:
24263979
62. MA Linden, JA Fletcher, EM Morris, GM Meers, ML Kearney, JM Crissey, MH Laughlin, FW Booth, JR
Sowers, JA Ibdah, JP Thyfault, and RS Rector. Combining Metformin and Aerobic Exercise Training in
the Treatment of Type 2 Diabetes and NAFLD in OLETF Rats. Am J Physiol Endocrinol Metab,
306(3):E300-10, 2014. PMID: 24326426
63. J Padilla, NT Jenkins, PK Thorne, K Duncan, NJ Fleming, NJ Harrison, DS Bayless, RD Sheldon, RS
Rector, and MH Laughlin. Differential regulation of adipose tissue and vascular inflammatory gene
expression by chronic systemic inhibition of NOS in lean and obese rats. Physiol Reports. 2(2):e00225,
2014.
64. J Padilla, NT Jenkins, PK Thorne, J Martin, RS Rector, J Davis, and MH Laughlin. Transcriptome-Wide
RNA Sequencing Analysis of Rat Skeletal Muscle Feed Arteries. Part II: Impact of Exercise Training in
Obesity. J Appl Physiol. 116(8):1033-47, 2014. PMID: 24408995
65. Jenkins NT, Padilla J, Thorne PK, Martin JS, Rector RS, Davis JW, Laughlin MH. Transcriptome-Wide
RNA Sequencing Analysis of Rat Skeletal Muscle Feed Arteries. Part I: Impact of Obesity. J Appl Physiol.
116(8):1017-32, 2014. PMID: 24436298
66. Crissey JM, Jenkins NT, Duncan KA, Thorne PK, Bayless DS, Vieira-Potter VJ, Rector RS, Thyfault JP,
Laughlin MH, Padilla J. Adipose tissue and vascular phenotypic modulation by voluntary physical activity
and dietary restriction in obese insulin resistant OLETF rats. Am J Physiol Integr Comp Physiol.
306(8):R596-606, 2014 PMID: 24523340
67. RD Sheldon, MH Laughlin, and RS Rector. Reduced hepatic eNOS phosphorylation is associated with
NAFLD and type 2 diabetes progression and is prevented by daily exercise in hyperphagic OLETF rats. J
Appl Physiol. 1;116(9):1156-64, 2014. PMID 24577062
68. Toedebusch RG, MD Roberts, KD Wells, JM Company, KM Kanosky, J Padilla, NT Jenkins, JW Perfield
II, JA Ibdah, FW Booth, RS Rector. Unique transcriptomic signature of omental adipose tissue in
Ossabaw swine: A model of childhood obesity. Physiol Genomics. 46(10):362-75, 2014 PMID: 24642759
69. MA Linden, JA Fletcher, EM Morris, GM Meers, MH Laughlin, FW Booth, JR Sowers, JA Ibdah, JP
Thyfault, RS Rector. Treating NAFLD in OLETF rats with vigorous-intensity interval exercise training.
Med Sci Sports Exerc. In Press June 30, 2014, PMID: 24983336
70. EM Morris, M Jackman, G Johnson, TW Liu, J Lopez, M Kearney, JA Fletcher, GM Meers, L Koch, S
Britton, RS Rector, JA Ibdah, PS MacLean, and John P. Thyfault. Intrinsic Aerobic Capacity Impacts
Susceptibility to Acute High-fat Diet-induced Hepatic Steatosis. Am J Physiol Endocrinol Metab.
307(4):E355-64, 2014 PMID 24961240
71. J Padilla, N Jenkins, P Thorne, J Martin, RS Rector, JW Davis, and MH Laughlin. Identification of genes
whose expression is altered by obesity throughout the arterial tree. Physiol Genomics. 15;46(22):821-32,
2014. PMID: 25271210
72. Y-H Hung, MA Linden, A Gordon, RS Rector, KK Buhman. Endurance Exercise Training Programs
Intestinal Lipid Metabolism in a Rat Model of Obesity and Type 2 Diabetes. Physiol Rep In Press 2015
Jan 19 PMID: 25602012
R. Scott Rector
7
73. Heden TD, Winn NC, Mari A, Booth FW, Rector RS, Thyfault JP, Kanaley JA. Post-dinner resistance
exercise improves postprandial risk factors more effectively than pre-dinner resistance exercise in patients
with type 2 diabetes. J Appl Physiol 2014 Dec 24. In Press. PMID:25539939
74. RD Sheldon, J Padilla, NT Jenkins, MH Laughlin, RS Rector. Chronic NOS inhibition accelerates NAFLD
progression in an obese rat model. Am J Physiol Gastrointest Liver Physiol 2015 Jan 8
doi:10.1152/ajpgi.00247.2014
75. AR Aroor, J Habibi, DA Ford, R Nistala, G Lastra, C Manrique, MM Dunham, KD Ford, JP Thyfault, EJ
Parks, JR Sowers, RS Rector. Dipeptidyl peptidase-4 inhibition ameliorates western diet-induced hepatic
steatosis and insulin resistance through hepatic lipid remodeling and modulation of hepatic mitochondrial
function. Diabetes, In Press. 2015 Jan 20. PMID: 25605806
Papers in Review
1.
MS Chiney, LC Ortinau, RS Rector, JW Perfield II, and LA Johnson. Sterculic Oil Reversal of Obesity
Mediated Alterations in Phase I and Phase II Drug Metabolism Enzyme Activity. Drug Metabolism Letters
In 2nd Review
2.
Hinton, PS, K Shankar, LS Eaton, RS Rector. Obesity-related changes in bone structural and material
properties in hyperphagic OLETF rats and protection by voluntary wheel running. Metabolism In 3rd
Review.
INVITED SEMINARS/LECTURES
1. Nutritional Sciences Departmental Seminar, April 28, 2005. RS Rector The effects of short-term weight
loss and weight maintenance on systemic inflammatory markers.
2.
University of Arizona- Diabetes and Endocrinology Group, November 16, 2006. RS Rector. The
antioxidative effects of exercise training- and diet-induced weight loss.
3.
Nutritional Sciences Departmental Seminar and Dissertation Defense, January 26, 2007. RS Rector.
Exercise and diet induced weight loss improves measures of oxidative stress and insulin sensitivity.
4.
Internal Medicine-Cardiology Grand Rounds-University of Missouri, Sept 20, 2007. RS Rector.
Antioxidative role of exercise and weight loss.
5.
Nutrition and Exercise Physiology Departmental Seminar, University of Missouri, April 24, 2008. RS
Rector. Potential mechanisms mediating exercise-associated attenuation of fatty liver disease.
6.
American College of Sports Medicine, National Meeting, Seattle WA, May, 2009. RS Rector. Potential
mechanisms mediating exercise-associated attenuation of fatty liver disease.
7.
American College of Sports Medicine, Central States Chapter, November 6, 2009. RS Rector. Negative
consequences of physical inactivity on liver health and disease development.
8.
American Association for the Study of Liver Diseases (AASLD), November 1, 2010. RS Rector. Exercise
and outcomes of fatty liver disease.
9.
Biomedical Sciences Departmental Seminar, University of Missouri, February 24, 2011. RS Rector.
Nonalcoholic Fatty Liver Disease: Changing the Course with Lifestyle Intervention
10. Interdepartmental Nutrition Program, Purdue University, November 2011. RS Rector. Nonalcoholic Fatty
Liver Disease: A Balancing Act
R. Scott Rector
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11. College of Osteopathic Medicine and Dept of Biological Sciences, William Carey University, February 13,
2012. RS Rector. A Translational Approach to Battle the Nonalcoholic Fatty Liver Disease Epidemic
12. Medical Pharmacology and Physiology, University of Missouri, March 13, 2012. RS Rector. Integrative
Approach to Combat Nonalcoholic Fatty Liver Disease
13. American College of Sports Medicine, National Meeting, May 31, 2012. RS Rector. Inactivity and NonAlcoholic Fatty Liver Disease
14. American College of Sports Medicine, Central States Chapter, October 19, 2012. RS Rector. Treating
Nonalcoholic Fatty Liver Disease: Does Exercise Modality Matter
15. Dorsett L. Spurgeon M.D. Distinguished Medical Research Award Seminar, University of Missouri,
November 15, 2012. RS Rector. Treating NAFLD in Children and Adults: Tools for Translation
16. MU-iCATS Translational Science Seminar Series, University of Missouri, December 11, 2012. RS
Rector. Treating NAFLD with Lifestyle Therapies
17. American College of Sports Medicine, National Meeting, May 30, 2014. RS Rector. Ossabaw Swine:
Modeling Childhood Obesity and Fatty Liver Disease
18. VA Mitochondrial Medicine Symposium, Invited Meeting June 2014. RS Rector. Mitochondrial
dysfunction in NAFLD, hepatic insulin resistance, and type 2 diabetes
19. American College of Sports Medicine, National Meeting, May 29, 2015. RS Rector. Intrahepatic Lipids:
Systemic Implications and Management with Lifestyle Modification
SYMPOSIUM CHAIR/CO-CHAIR
American College of Sports Medicine, National Meeting, May 2009. Seattle, WA
Session Title: Prevention of Fatty Liver Disease through Lifestyle Modification: From Cellular Mechanisms to
Clinical Applications. JP Thyfault and RS Rector, co-chairs.
Obesity Society, National Meeting, October 2011. Orlando, FL
Session: Fatty acid metabolism and muscle. RS Rector and Jill Kanaley, co-chairs
American Diabetes Association, National Meeting, June 2013, Chicago, IL
Session: Exercise in Humans–Efficacy and Possible Mechanisms. RS Rector, moderator
American College of Sports Medicine, National Meeting, May 2014. Orlando, FL
Session: Exercise and Blood Flow Restriction. RS Rector, moderator
Obesity Society, National Meeting, October 2015, Los Angeles, CA
Session: Mitochondrial Energetics and Obesity. RS Rector, Chair
PROFESSIONAL MEMBERSHIPS
1998-Present: American College of Sports Medicine (ACSM)
2003-Present: American Physiological Society (APS)
2010, 2013-Present: American Diabetes Association (ADA)
2010-Present: American Association for the Study of Liver Diseases (AASLD)
2011-Present: The Obesity Society (TOS)
AD HOC REVIEWER
American Journal of Physiology-Endocrinology and Metabolism
American Journal of Physiology-Gastrointestinal and Liver Physiology
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
R. Scott Rector
Journal of Applied Physiology
Journal of the Cardiometabolic Syndrome
Antioxidants and Redox Signaling
Advances in Physiology Education
Metabolism
Liver International
Journal of Hepatology
Hepatology
Journal of Nutrition and Metabolism
Preventing Chronic Disease
European Journal of Applied Physiology
PLoS ONE
Medicine Science in Sports and Exercise
Obesity
Nutrients
FEBS Journal
EDITORIAL BOARDS
Journal of CardioRenal Medicine
Frontiers in Physiology
August 2011-present
May 2012-present
EXTERNAL GRANT REVIEWER
Longer Life Foundation—Washington University, July 2012
University of Missouri Research Board, Nov 2012
NIH-NIDDK –Subcommittee C Study Section, June 2013
French National Research Agency, June 2014
NIH-Integrative Nutrition and Metabolic Processes (INMP) Study Section, October 2014
HONORS AND AWARDS
1998: Who’s Who in American Colleges and Universities
1999: Outstanding Graduate Student- Department of HPER. Arkansas State University
2002: Outstanding Graduate Student Award- Exercise Physiology. University of Missouri
2005, 2006: Graduate Student Poster Award- Central States Chapter, ACSM
2005, 2006: The Chancellor's List
2008: Digestive Disease Week--Poster of Distinction Award
2011: American Association of Study of Liver Diseases—Presidential Plenary Session Seminar
2012: MU School of Medicine: Dorsett L. Spurgeon M.D. Distinguished Medical Research Award
FELLOWSHIPS/SCHOLARSHIPS
2005-2006: James L. McGregor Scholarship in Health and Exercise Sciences, University of Missouri
2006-07: HEALTH ACTIVITY CENTER-M. HAROLD LAUGHLIN SCHOLARSHIP AWARD WINNER
GRANTS/SUPPORT
Current Research Support
1 IK2 BX001299-01
Career Development Award-2
(RS Rector, PI, 75%)
7/1/2011-6/30/2016
Veterans Health Administration
$850,000 in total costs over 5 years
Hepatic mitochondria and insulin resistance in fatty liver and type 2 diabetes
The goal of this project is to test the hypothesis that hepatic insulin resistance associated with NAFLD
develops secondary to mitochondrial dysfunction and is a significant contributing factor in the development of
type 2 diabetes, and to determine the effectiveness of daily exercise vs. caloric restriction (with and without
metformin) in the treatment of NAFLD and type 2 diabetes.
9
R. Scott Rector
10
Solae/DuPont
(RS Rector, Co-PI, 5%; JP Thyfault, Co-PI)
1/01/15-12/31/2015
$113,000 in total costs over 1 year
Soy protein in the prevention of hepatic steatosis and skeletal muscle lipid peroxidation
The goal of this project is to test the hypothesis that soy protein isolate can be used in the prevention of
hepatic and skeletal muscle lipid accumulation through enhancement in mitochondrial metabolism.
Mizzou Alumni Association-Richard Wallace Faculty Incentive Grant
$3,000 over 1 year
(RS Rector, PI)
1/1/2015-12/31/2015
Role of hepatic endothelial nitric oxide synthase in nonalcoholic fatty liver disease progression
The goal of this project is to examine the role of hepatic endothelial nitric oxide synthase in normal hepatocyte
mitochondrial function and prevention of hepatocellular inflammation.
University of Missouri-Research Board Grant
$45,000 over 1 year
(RS Rector, Co-PI: CA Emter, Co-PI)
4/1/2015-3/31/2016
Translational swine model for the study of HFpEF
The goal of this project is to develop, characterize, and examine mechanisms impacting the progression of
heart failure with preserved ejection fraction (HFpEF) in a female Ossabaw swine model of obesity and the
metabolic syndrome.
University of Missouri-Research Council
$10,000 over 1 year
(RS Rector, PI)
4/1/2015-3/31/2016
Aerobic exercise training as a mitigator of nonalcoholic fatty liver disease related fibrosis
The goal of this project is to determine whether exercise can effectively treat more advanced stages of liver
disease, particularly hepatic fibrosis though the upregulation in fibrosis resolution pathways.
Research Support-In Submission or to be re-submitted
Submitted December 2014: Solae/DuPont Young Professor Grant $100,000 over 2 years. (RS Rector, PI,
10%). Soy protein isolate and hepatic endothelial nitric oxide synthase activation in the prevention of
nonalcoholic steatohepatitis.
Submitted January 2015: American Heart Association- $65,000 per year for 3 years. (W Fay, PI; RS Rector
Co-I, 2%). Pharmacological inhibition of plasminogen activator inhibitor-1 (PAI-1) on atherogenesis and
obesity-induced metabolic disease in Ossabaw swine.
Resubmitted March 2015: NIH R01. (RS Rector, PI, 40%). Fructose, Microbiota and Gut Integrity in a Swine
Model for Juvenile NASH. ($2,446,112 in total costs over 5 years).
Submitted March 2015: NIH R01. (MH Laughlin, PI; RS Rector, Co-I, 5%) Training-Muscle Blood Flow and
Capillary Dynamics
Submitted March 2015: VA Merit Grant (RS Rector, PI, 62.5%) Hepatic eNOS and Mitochondrial Function in
NASH. ($977,000 in total costs over 4 years).
Resubmit March 2016: NIH R01. (CA Emter-PI, RS Rector, Co-I, 10%) Diet, Exercise, and Lipid Mediated
Mitochondrial Dysfunction in Heart Failure
Resubmit June 2015: NIH R01. (JA Ibdah-PI, RS Rector Co-I, 20%) Lifestyle Modifications in the treatment of
NASH
Completed Research Support
VA-Shared Equipment Evaluation Program (ShEEP Project)
(RS Rector and JP Thyfault, Co-PIs)
Awarded June 2014
$55,000 in total costs
Grant awarded for the purchase of Core Research Equipment. Oroboros Respiratory System
R. Scott Rector
11
VA-Shared Equipment Evaluation Program (ShEEP Project)
(RS Rector and JP Thyfault, Co-PIs)
Awarded June 2013
$154,000 in total costs
Grant awarded for the purchase of Core Research Equipment. Echo MRI System, (4-in-1/1100 magnetic
resonance analyzer).
JR Albert Foundation
(RS Rector, PI)
4/1/2012-8/30/2013
$110,000 in total costs over 1.5 year
The goal of this project is to characterize the inflammatory phenotype of regionally distinct adipose tissue
depots (subcutaneous and intra-abdominal) in obese children and correlate these findings based on the
presence and severity of nonalcoholic fatty liver from liver biopsies.
Allen Foundation, Inc
(RS Rector, PI)
7/1/2011-12/30/2012
$82,500 in total costs over 1 year
Characterization of a Biomedical Model for Childhood Obesity
The goal of this project is to development an appropriate animal model of childhood obesity to study the
development and progression of obesity and obesity associated metabolic disorders, including fatty liver
disease, insulin resistance, and adipose tissue inflammation.
1F32 DK083182-01
(RS Rector, PI)
9/01/2008 - 6/30/2010
NIH:NIDDK
Ruth L. Kirschstein National Research Service Award (NRSA)- Post-Doctoral Training Grant
Exercise, mitochondrial function, and fatty acid oxidation in fatty liver disease
The goal of this project is to examine the impact of exercise on mitochondrial function, insulin resistance, and
non-alcoholic fatty liver disease in knockout mice heterozygous for mitochondrial trifunctional protein, a primary
disruption in mitochondrial fatty acid β-oxidation.
Role: PI
NIH T32 AR48523
(R. Terjung, PI; RS Rector, Trainee) 8/1/2003 – 1/31/2007
NIH-Institutional Training Grant
Exercise and Health: Integration from Molecule to Patient.
Pre-Doctoral Training Grant
Role: Trainee
Unfunded Research Submissions
United Mitochondrial Disease Foundation Grant-2010, $100,000, Unfunded (RS Rector, PI)
American Diabetes Association- Innovation Award- 2010, $150,000, Unfunded (RS Rector, PI)
American Diabetes Association 2013- Exercise, postprandial glucose, and oxidative stress in type 2 diabetes
(JP Thyfault-PI, RS Rector Co-I, 5%)
NIH R01 Microcirculatory Adaptation: Role in Healthy Adipose Tissue Phenotype in Obesity 2013 (MH
Laughlin-PI, RS Rector, Co-I, 5%)
AMER HEART ASSN 2014: Role of Fitness and Adipose Tissue Phenotype on Ovariectomy-Associated
Metabolic Dysfunction (VJ Vieira-Potter-PI, RS Rector, Co-I, 5%)
Diamedica, 2014-Effects of DM199 on prevention of western diet induced NAFLD in obese Ossabaw Swine,
Total Costs $299,450, Unfunded (RS Rector, 10% and J Padilla, Co-PIs)
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R. Scott Rector
ADVISING/SERVICE/TEACHING
University of Missouri
ADVISING
PhD dissertation committees
Tim Heden- Exercise Physiology
(Mentor-Dr. Jill Kanaley)
Start Finish
01/12-07/14
Laura Ortinau-Nutritional Sciences
(Mentor-Pam Hinton)
07/14-
MS Thesis committees
DJ Oberlin– Exercise Physiology
(Mentor-Dr. John Thyfault)
Andrew Dawson-Exercise Physiology
(Mentor-Dr. Pam Hinton)
Tim Sinak-Exercise Physiology
(Mentor-Dr. Pam Hinton)
Nathan Winn-Exercise Physiology
(Mentor-Dr. Jill Kanaley)
Nan Lin-Nutritional Sciences
(Mentor- Dr. Pam Hinton)
Current graduate student advisees
Justin A. Fletcher – Exercise Physiology Doctoral Student
(Co-Mentor with Dr. John Thyfault)
Melissa Linden- Exercise Physiology Doctoral Student
(Mentor)
Ryan Sheldon-Exercise Physiology Doctoral Student
(Mentor)
Kevin Eck- Exercise Physiology Doctoral Student
Research Fellows
Abhishek Choudhary-- Gastroenterology
(Co-Mentor with Dr. Jamal Ibdah)
Kristi Lopez-Gastroenterology
(Mentor)
Sameer Siddique-Gastroenterology
(Mentor)
01/11-12/11
08/10-7/11
09/11-12/12
05/11-08/14
11/13-
08/10-12/14
Graduated 12/14
01/1208/1208/15-
08/10-12/12
09/12-Present
09/12-12/12
Summer Research Interns
Nicholas Shea-Truman State University
(Mentor)
Summer 2013
Colin Schuster-MU-SOM Medical Student -First year
Summer 2015
Undergraduate Mentees
Craig Meers
Mahir Khan
Timothy Tan
Kelly Stromsdorfer
Raisa Buenaventura
Laura Taylor
Ryan Toedebusch
Radheya Naik
Tasnim Haq
13
R. Scott Rector
University of Guelph
Member: Special Graduate Faculty; Department of Human Health and Nutritional Sciences
Will Peppler, PhD Candidate
October 2014
SERVICE
University of Missouri Committees
Judge- MU SOM-Health Sciences Research Day
11/2011; 11/2012; 11/2013; 11/2014
Co-Organizer for Nutrition and Exercise Research Week, NEP
Spring 2011
Faculty search committee member-GI
2010, 2011, 2012, 2014
Dept of Medicine Research Council-Committee member
07/11-Present
Organizer for Nutrition and Exercise Physiology Seminar Series
Fall 2011, Spring 2012
Exercise Physiology Graduate Curriculum Committee
Fall 2012MU CTSA Stakeholder Council-Junior Faculty Representative
Fall 2012MU-School of Medicine Research Council Committee Member
July 2013MU-Division of GI, Hepatology Fellow Selection Committee
2013, 2014, 2015
MU- GI, Gastroenterology Fellowship Program Selection Committee
2013, 2014
Nutrition & Exercise Physiology, Faculty Search Committee-Teaching Track Fall 2013
Nutrition & Exercise Physiology, Faculty Search Committee-Tenure Track
Fall 2013
MU Scientific Peer Review Committee Member
Feb 2014Harry S Truman Memorial VA Hospital
Voting Member of the Subcommittee for Animal Safety (VA-IACUC)
07/10-Present
Vice Chairman: 07/12-07/14
Chairman: 07/14-Present
TEACHING
University of Missouri
2001-2003
Graduate Research Assistant: Department of Nutritional Sciences
Teaching assistant:
Exercise Physiology courses
Exercise Physiology Lab sections
Independently taught Exercise Physiology Lab sections
Fall 2011
NS 8850-Advanced Exercise Physiology: Department of Nutrition and Exercise Physiology
Co-Instructors: J Kanaley and RS Rector
Spring 2012
NS4001/7001: Etiology of Obesity: Department of Nutrition and Exercise Physiology
Co-Instructors: RS Rector and JW Perfield
Fall 2012
NS 8850-Advanced Exercise Physiology: Department of Nutrition and Exercise Physiology
Co-Instructors: J Kanaley and RS Rector
Fall 2010Present
Ongoing contributions to the GI Fellowship Program, including numerous educational lectures
Fall 2013
MU School of Medicine-Patient Based Learning, Block 2; Co-Facilitator with Alan Parrish, solo
last 5 weeks
Spring 2014
MU School of Medicine-Patient Based Learning, Block 7; Lecture on NAFLD
Fall 2014
MU School of Medicine-Patient Based Learning, Block 2; Facilitator
Fall 2014
NS 8850-Advanced Exercise Physiology: Department of Nutrition and Exercise Physiology
Co-Instructors: J Kanaley and RS Rector
Spring 2015
R. Scott Rector
MU School of Medicine-Patient Based Learning, Block 7; Lecture on NAFLD
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Guest Lectures at MU
11/09/04- NS8850 Advanced Exercise Physiology- Exercise and Gene Expression
11/04/05- NS8850 Advanced Exercise Physiology- Overview of Gene Expression
10/11/04- NS1340 Nutrition and Fitness- Protein and Fat Utilization during Exercise
10/12/05- NS1340 Nutrition and Fitness- Substrate Utilization during Exercise
10/25/07- NS8850 Advanced Exercise Physiology-Gene Expression-Tools and Techniques
10/27/09- NS8850 Advanced Exercise Physiology-Use of Molecular Biology in Exercise Physiology
03/11/10- NS2001 Landscape of Obesity-Non-Exercise Activities and Their Impact on Obesity
03/15/11- NS2222 Landscape of Obesity-Non-Exercise Physical Activity: Role in Obesity Prevention
03/13/12- NS2222 Landscape of Obesity-Non-Exercise Physical Activity: Vital for Obesity Prevention
03/13/13- NS2222 Landscape of Obesity-Non-Exercise Physical Activity: Vital for Obesity Prevention
03/18/14- NS2222 Landscape of Obesity-NEAT: What is it good for?
Arkansas State University
1998-1999 Graduate Teaching Assistant: Department of Health, Physical Education and Sports Sciences
Exercise Physiology
Kinesiology
Strength and Conditioning
Research Methods and Statistics
1999-2001 Adjunct Faculty: Department of Health, Physical Education and Sports Sciences
Taught following courses:
Nutrition and Fitness (4 sections per semester)
Kinesiology (1 section)
American College of Sports Medicine
May 2007- ACSM Health/Fitness Instructor Workshop—Basic Exercise Physiology Lecture
May 2008- ACSM Health/Fitness Instructor Workshop—Basic Exercise Physiology Lecture
PUBLISHED ABSTRACTS
1.
T.R. Thomas, J.A. Pellechia, G.Y. Sun, RS Rector, and M.H. Laughlin. Effects of exercise training on the lipoprotein
profile of swine on an atherogenic diet. Med Sci Sports Exerc 34(5) 2002.
2.
RS Rector, T.R. Thomas, Y. Liu, K.K. Henderson, D. Holiman, and M. Sturek. Postprandial lipemia after acute
exercise in Yucatan miniature swine. Med Sci Sports Exerc 35(5):A457, 2003.
3.
RS Rector, E.A. Mokelke, N.M. Zafar, T.R. Thomas, M. Sturek. Exercise training prevents elevation of C-reactive
protein in diabetic dyslipidemic Yucatan miniature swine. FASEB J. 18 (5):A1297, 2004.
4.
K. K. Henderson, RS Rector, Y. Liu, T.R. Thomas, J.R. Turk, M.H. Laughlin and M. Sturek. Trans fat increases
total/HDL-cholesterol ratio in a porcine model of cardiovascular disease. FASEB J. 18(4):A563, 2004.
5.
TS Altena, JL Michaelson, SD Ball, BL Giles, RS Rector, and TR Thomas. Lipoprotein subfraction changes after
short term continuous or intermittent exercise training. Med Sci Sports Exerc 36(5):S142, 2004.
RS Rector, B.K. Smith, G.Y. Sun, Y. Liu, and T.R. Thomas. C-reactive Protein and Secretory Phospholipase A2 are
Unaffected by Exercise or Omega-3 Fatty Acid Supplementation. Med Sci Sports Exerc 36(5):S326, 2004. Oral
Presentation.
6.
7.
RS Rector, M.W. McClanahan, B.L. Giles, B.W. Toedebusch, and T.R. Thomas. Effects of short-term weight loss
and regain on measures of insulin resistance and the insulin-like growth factor axis. FASEB J 19(4):A131, 2005.
8.
RS Rector, E.J. Stites, B.L. Giles, B.W. Toedebusch, M.W. McClanahan, and T.R. Thomas. The effects of shortterm weight loss and partial weight regain on systemic inflammatory markers. Med Sci Sports Exerc 37(5):A752,
2005.
R. Scott Rector
9.
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B. L. Giles, RS Rector, B. W. Toedebusch, M. W. McClanahan, R.H. Cox, P. S. Hinton, and T. R. Thomas. The
effects of exercise training on maintenance of abdominal adiposity and lipoproteins during weight regain. Med Sci
Sports Exerc 37(5):A1366, 2005.
10. RS Rector, V.A. Viele, P.S. Hinton, and T.R. Thomas. Aerobic Training Increases Markers of Bone Formation
During Short-Term Weight Loss. Med Sci Sports Exerc 2006.
11. Y. Liu, M.A. Linden, T.R. Jarvis, RS Rector, and T.R. Thomas. Omega-3 fatty acid supplementation and exercise
training attenuate postprandial lipemia in sedentary individuals. Med Sci Sports Exerc 2006.
12. RS Rector, Shana O. Warner, Ying Liu, Pamela S. Hinton, Tom R. Thomas. Exercise and diet induced weight loss
improves markers of insulin sensitivity and oxidative stress. Med Sci Sports Exerc 2007.
13. M.A. Linden, RS Rector, T.S. Altena, B.K. Smith, J.Q. Zhang, G.G. Ziogas, Y. Liu, and T.R. Thomas. Estimating
postprandial lipemia using a single point triglyceride concentration. Med Sci Sports Exerc 2007.
14. SO. Warner, RS Rector, Y Liu, P S. Hinton, DR. Huyette, TR. Thomas. Changes in Abdominal Adipose Tissue
Compartments with Changes in Body Weight. Med Sci Sports Exerc 2007.
15. S P. Naples, S O. Warner, J P. Thyfault, RS Rector, Y Liu, P S. Hinton, TR. Thomas. Diet- and Exercise-Induced
Weight Loss Lowers Intermuscular Fat and Low-Density Muscle Attenuation in Overweight Individuals. Med Sci
Sports Exerc 2007.
16. J Company, Y Liu, RS Rector, S Warner, T R Thomas. Scoring System for the Severity of the Metabolic Syndrome.
Med Sci Sports Exerc 2007.
17. Laye MJ, Borengasser SJ, RS Rector, Thyfault JT, Booth FW. Adipose tissue compensates to maintain whole body
insulin sensitivity 173 hours following the cessation of voluntary running in rats. FASEB J 2007.
18. RS Rector, JP Thyfault, RT Morris, MJ Laye, SJ Borengasser, FW Booth, and JA Ibdah. Daily exercise increases
hepatic fatty acid oxidation and prevents steatosis in Otsuka Long-Evans Tokushima Fatty (OLETF) rats.
Hepatology 46(4) Suppl: 758A, 2007. Abstract 1170.
19. JP Thyfault, RS Rector, Uptergrove, GM, Morris, EM, Wei, Y, Laye, MJ, Clark, SE, Koch, LG, Britton, SL, and JA
Ibdah. Rats selectively bred for low endurance capacity display evidence for the development of NAFLD at an early
age. Hepatology 46(4) Suppl: 308A, 2007. Abstract 161.
20. CA Peterson, S Ring, J Loethen, RS Rector, T Thomas, PS Hinton. Vitamin D status is unaltered by mild weight
reduction in obese premenopausal women. FASEB J 2008.
21. R Rogers, RS Rector, M Ruebel, M Widzer, PS Hinton. Lean body mass predicts bone mineral density in male
resistance-trained athletes. Med Sci Sports Exerc 2008.
22. Borengasser SJ, Naples SP, Rector RS, Mikus CA, Uptergrove GM, Morris EM, Koch LG, Britton SL, Ibdah JA and
Thyfault JP. Skeletal muscle mitochondrial oxidative capacity and metabolic responses to a high fat diet or aging in
rats bred for high and low aerobic capacity. Diabetes, 57 (supplement 1). 1539P, 2008.
23. RS Rector, JP Thyfault, MJ Laye, RT Morris, SJ Borengasser, GM Uptergrove, FW Booth, and JA Ibdah. Physical
activity and short-term inactivity modulate hepatic fatty acid oxidation and lipogenesis proteins in Otsuka Long-Evans
Tokushima Fatty (OLETF) rats. Hepatology 2008. Poster of Distinction Award Winner.
24. NM Szary, GM Uptergrove, SP Naples, S Ridenhour, R Gitan, RS Rector, JP Thyfault, SD Shukla, JA Ibdah. Mice
heterozygous for a defect in mitochondrial trifunctional protein are susceptible for development of hepatic steatosis
when fed a diet rich in fat with and without ethanol. Abstract 1166, Hepatology 48(4) Suppl, October 2008.
25. JP Thyfault, RS Rector, SP Naples, GM Uptergrove, SJ Borengasser, EM Morris, Y Wei, S Ridenhour, KL Fritsche,
LG Koch, SL Britton, JA Ibdah. Hepatic steatosis and metabolic responses to high fat feeding in female rats bred for
high and low aerobic capacity. Abstract 1181, Hepatology 48(4) Suppl, October 2008.
R. Scott Rector
16
26. RS Rector, JP Thyfault, GM Uptergrove, SP Naples, SJ Borengasser, CR Mikus, MJ Laye, MH Laughlin, FW Booth,
and JA Ibdah. Effects of daily physical activity on the natural history of NAFLD and insulin resistance in Otsuka
Long-Evans Tokushima Fatty (OLETF) rats. Abstract 1203, Hepatology 48(4) Suppl, October 2008.
27. CR Mikus, RS Rector, PK Thorne, EM Morris, FW Booth, JA Ibdah, MH Laughlin, JP Thyfault. Exercise maintains
microvascular reactivity to insulin in skeletal muscle arterioles of hyperphagic rats prone to obesity. FASEB J 2009.
28. Choudhary A, Szary NM, Bechtold ML, Puli SR, Rector RS, Thyfault JP, Ibdah JA, Bechtold ML. Insulin sensitizers
for the management of non-alcoholic fatty liver disease: A meta-analysis of randomized controlled trials.
Gastroenterology 2009;136(5-S1):A-845 (T1008).
29. RS Rector, JP Thyfault, GM Uptergrove, EM Morris, SP Naples, SJ Borengasser, CR Mikus, MJ Laye, MH Laughlin,
FW Booth, and JA Ibdah. Loss of mitochondrial content and function contribute to the natural history of nonalcoholic
fatty liver disease in a hyperphagic obese rodent model. Gastroenterology 2009;136:A-767 (T1620).
30. RS Rector. Potential Mechanisms Mediating Exercise-Associated Attenuation of Fatty Liver Disease. MSSE 41(5):
48 (377), 2009. Oral Presentation.
31. TR Thomas, SO Warner, Y Liu, MA Linden, PS Hinton, KC Dellsperger, A Chockalingham, AT Whaley-Connell, RS
Rector, JP Thyfault, DR Huyette. Exercise and the Metabolic Syndrome with Weight Regain. MSSE 41(5): S588,
2009.
32. RS Rector, GM Uptergrove, RS Gitan, and JA Ibdah. Daily exercise attenuates the development of hepatic
steatosis in mice heterozygous for a mitochondrial trifunctional protein defect. Abstract, Hepatology Suppl, October
2009.
33. NM Szary, GM Uptergrove, RS Rector, S Ridenhour, JP Thyfault, SL Britton, LG Koch, ML Bechtold, SD Shukla,
and JA Ibdah. High Intrinsic Aerobic Capacity Does Not Protect Against Hepatic Steatosis From Chronic Ethanol
Intake. Abstract , Hepatology Suppl, October 2009.
34. EA Dannecker, Y Liu, RS Rector, TR Thomas, C Leeuwenburgh, and BK Ray. Effect of intermittent fasting for five
consecutive days on exercise-induced muscle damage in humans. MSSE 2010.
35. SJ Borengasser, RS Rector, GM Uptergrove, EM Morris, JL Libla, FW Booth, KL Fritsche, JA Ibdah, and JP
Thyfault. Exercise and omega-3 fatty acids as treatments for nonalcoholic fatty liver disease. Diabetes, 2010
36. RS Rector, GM Uptergrove, EM Morris, SJ Borengasser, MH Laughlin, FW Booth, JP Thyfault, and JA Ibdah.
Attenuation of weight gain through daily exercise versus caloric restriction and prevention of nonalcoholic fatty liver
disease in hyperphagic OLETF rats. Hepatology, Suppl, 2010
37. CR Mikus, BT Roseguini, GM Uptergrove, EM Morris, RS Rector, JA. Ibdah, JP Thyfault, and MH Laughlin. Chronic
wheel running selectively augments insulin-stimulated vasodilation in arterioles from the white gastrocnemius.
FASEB J 2011.
38. RS Rector, GM Meers, S Ridenhour, JA Ibdah. Hepatic insulin resistance in mice heterozygous for a mitochondrial
trifunctional protein defect. Oral Plenary Presentation. Hepatology, Suppl, 2011.
39. EM Morris, GM Uptergrove, G Powell, RS Rector, JA Ibdah, and JP Thyfault. Daily exercise results in increased
hepatic fatty acid oxidation and mitochondrial content in rat primary hepatocytes. Hepatology, Suppl, 2011.
40. DJ Oberlin, CR Mikus, ML Kearney, JA Fletcher, PS Hinton, JA Kanaley, RS Rector, HJ Leidy, JP Thyfault. A single
exercise bout does not improve glycemic control in volunteers with type 2 diabetes. Med Science Sports Exerc,
Supplement 2012.
41. JA Fletcher, GM Meers, JA Ibdah, JP Thyfault, and RS Rector. Daily exercise and caloric restriction impact fibroblast
growth factor-21 in hyperphagic OLETF rats. MSSE Supplement 2012.
42. RS Rector, GM Meers, JA Fletcher, MA Linden, MH Laughlin, FW Booth, JP Thyfault, and JA Ibdah. Moderate vs.
vigorous intensity exercise training in the treatment of type 2 diabetes and nonalcoholic fatty liver in the hyperphagic,
obese OLETF rat. Hepatology, Suppl, 2012.
R. Scott Rector
17
43. NT Jenkins, J Padilla, JS Martin, JM Crissey, JP Thyfault, RS Rector, and M Laughlin. Differential vasodilator
effects of insulin between gastrocnemius and soleus muscle feed arteries: Role of endothelin-1. The Physiologist:
55(6), 2012.
44. EM Morris, GME Meers, TW Liu, ML Kearney, AL Blandon, JA Fletcher, RS Rector, JP Thyfault. High intrinsic
aerobic capacity is associated with greater liver fatty acid oxidation adaptability. The Physiologist: 55(6), 2012.
45. JP Thyfault, EM Morris, RS Rector. Intrinsic Fitness and Exercise Prevent Hepatic Lipotoxicity. The Physiologist:
55(6), 2012.
46. RG Toedebusch, KD Wells, FW Booth, RS Rector. Molecular signatures of adipose tissue in an Ossabaw swine
model of childhood obesity using transcriptome analysis. The Physiologist: 55(6), 2012.
47. JA Fletcher, GM Meers, MA Linden, ML Kearney, EM Morris, JP Thyfault, RS Rector. Impact of voluntary wheel
running and treadmill exercise training on hepatic mitochondrial metabolism and function. The Physiologist: 55(6),
2012.
48. SB Bender, JW Davis, RS Rector, MH Laughlin, JR Sowers. Characterization of the coronary vascular
transcriptome in a rat model of metabolic syndrome. FASEB J 2013.
49. CA Emter, RS Rector, CP Baines, KD Ford, DA Ford. Chronic Interval Exercise Modifies the Myocardial Lipid
Profile in a Miniature Swine Model of Heart Failure with Preserved Ejection Fraction. FASEB J 2013. Oral
Presentation
50. S Lee, FW Booth, RS Rector, MA Hill. Obesity leads to altered vasomotor function in juvenile Ossabaw pigs.
FASEB J 2013.
51. MA Linden, GM Meers, JA Fletcher, S Siddique, MH Laughlin, FW Booth, JA Ibdah, JP Thyfault, and RS Rector.
Metformin, Aerobic Exercise, and the Combination in the Treatment of Type 2 Diabetes and NAFLD in OLETF rats.
FASEB J 2013. Oral Presentation
52. Ryan D. Sheldon, Grace M. Meers, M. Harold Laughlin, R. Scott Rector. Reduced Hepatic eNOS Phosphorylation
in Sedentary Hyperphagic OLETF Rats is Prevented by Voluntary Wheel Running. Med Sci Sport Exerc Suppl 2013.
53. J Padilla, NT Jenkins, S Lee, H Zhang, J Cui, MY Zuidema, C Zhang (deceased), MA Hill, JW Perfield II, JA Ibdah,
FW Booth, JW Davis, MH Laughlin, RS Rector. Juvenile obesity in Ossabaw swine produces artery-specific
transcriptional changes. Med Sci Sport Exerc Suppl 2013
54. MA Linden, GM Meers, KM Kanosky, JA Fletcher, MH Laughlin, JP Thyfault, and RS Rector. Protection against
NAFLD development following prior physical activity versus caloric restriction in OLETF rats. Med Sci Sport Exerc
Suppl 2013
55. NT Jenkins, J Padilla, RS Rector, and MH Laughlin. Physical activity increases β-adrenergic and natriuretic peptide
receptor mRNAs in adipose tissue of OLETF rats. Med Sci Sport Exerc Suppl 2013
56. JA Fletcher, GM Meers, MA Linden, ML Kearney, EM Morris, JP Thyfault, and RS Rector. Impact of voluntary wheel
running in combination with overnight fasting on hepatic mitochondrial metabolism and function. Med Sci Sport
Exerc Suppl 2013
57. EM Morris, GME Meers, JA Fletcher, ML Kearney, TW Liu, AM Hinds, RS Rector, JA Ibdah, LG Koch, SL Britton,
JP Thyfault. High Intrinsic Aerobic Capacity Prevents Development of Hepatic Steatosis Following an Acute HighFat Diet. Diabetes 62:Suppl 1, 2013.
58. EM Morris, MR Jackman, GC Johnson, GME Meers, J Houser, LG Koch, SL Britton, RS Rector, JA Ibdah, PS
MacLean, JP Thyfault. High intrinsic aerobic capacity protects against 3-day high fat diet induced hepatic steatosis
through increased fat utilization and energy expenditure. Hepatology, Suppl, 2013.
59. RD Sheldon, J Padilla, N Jenkins, MH Laughlin, RS Rector. Nitric oxide synthase inhibition exacerbates liver injury
in an obese rat model of NAFLD. FASEB J Suppl 2014
60. NT Jenkins, J Padilla, PK Thorne, JS Martin, RS Rector, JW Davis, MH Laughlin. Transcriptome-Wide RNA
Sequencing Analysis of Rat Skeletal Muscle Feed Arteries: Impact of Obesity. FASEB J Suppl 2014
R. Scott Rector
18
61. MA Linden*, KT Lopez, JA Fletcher, GM Meers, S Siddique, EM Morris, JM Crissey, ML Kearney, MH Laughlin, JR
Sowers, JP Thyfault, JA Ibdah, and RS Rector. Improved efficacy of metformin therapy when combined with caloric
restriction in the treatment of type 2 diabetes and NAFLD in OLETF rats. FASEB J Suppl 2014
62. RJ Scroggins, J Padilla, R Welly, D Jackson, TN Smith, VJ Vieira-Potter, RS Rector. Obesity-prone female
ossabaw pigs are protected against western diet-induced adipose tissue inflammation and immune cell infiltration.
FASEB J Suppl 2014
63. HT Yang, RS Rector, PK Thorne, X Chen, MH Laughlin. Increases in rat adipose blood flows following bolus
intraperitoneal injection of glucose. FASEB J Suppl 2014
64. MA Linden, RD Sheldon, JA Fletcher, GM Meers, MH Laughlin, JP Thyfault, and RS Rector. Exercise of different
intensities alter hepatic mRNA expression of M1/M2 polarization markers in OLETF rats. Med Sci Sport Exerc Suppl
2014
65. JA Fletcher, GN Ruegsegger, KM Kanosky, FW Booth, JP Thyfault, and RS Rector. Hepatic mitochondrial content
and function in rats selectively bred for high vs. low voluntary running. Med Sci Sport Exerc Suppl 2014
66. JM Crissey, NT Jenkins, KA Duncan, PK Thorne, DS Bayless, VJ Vieira-Potter, RS Rector, JP Thyfault, MH
Laughlin, J Padilla. Adipose Tissue and Vascular Phenotypic Modulation by Voluntary Physical Activity and Dietary
Restriction in Obese Insulin Resistant OLETF Rats. Med Sci Sport Exerc Suppl 2014
67. EM Morris, GME Meers, RS Rector, JA Ibdah, LG Koch, SL Britton, JP Thyfault. High Intrinsic Aerobic Capacity
Prevents Development of Insulin Resistance Following Acute High-Fat Diet Challenge. Diabetes Suppl 2014
68. RS Rector, RD Sheldon, KM Kanosky, MA Linden, KD Wells, L Miles, JW Perfield II, SA Xanthakos, and TH Inge.
Transcriptomic differences in intra-abdominal adipose tissue in extremely obese adolescents with different stages of
nonalcoholic fatty liver disease. Obesity Suppl 2014
69. RS Rector, MA Linden, GM Meers, KM Kanosky, M Ruebel, JW Perfield II, JA Ibdah, and FW Booth. Modeling
childhood obesity and nonalcoholic fatty liver disease in juvenile Ossabaw miniature swine fed a western diet.
Obesity Suppl 2014
70. EM Morris, S Borengasser, GME Meers, LG Koch, SL Britton, RS Rector, K Shankar, and JP Thyfault. Distinct
Transcriptomic Signatures Associated with Protection Against High Fat Diet-Induced Hepatic Steatosis in Rats with
High Intrinsic Aerobic Capacity. Obesity Suppl 2014
71. RD Sheldon, MA Linden, GM Meers, EM Morris, MH Laughlin and RS Rector. eNOS Deficiency Increases
Susceptibility to Western Diet Induced Hepatic Mitochondrial Dysfunction. FASEB Journal, Suppl 2015, John Forte
GIL Section Distinguished Abstract Plenary Session
72. BS Ferguson, TD Olver, RD Sheldon, MA Linden, CA Emter, RS Rector, MH Laughlin. COX Inhibitor Indomethacin
Attenuates Phenylephrine Mediated Vasoconstriction in Rat Aorta. FASEB Journal, Suppl 2015.
73. TD Olver, BS Ferguson, RD Sheldon, MA Linden, CA Emter, RS Rector and MH Laughlin. Type 2 Diabetes Alters
Nitric Oxide Signaling in the Rat Aorta. FASEB Journal, Suppl 2015.
74. JL Rowles, JA Fletcher, TM Zidon, RJ Scroggins, Y-Min Park, JW Perfield, JP Thyfault, RS Rector, J Padilla, VJ
Vieira-Potter. Novel effects of FGF21 and exercise on brown adipose tissue inflammation. FASEB Journal, Suppl
2015.
75. MA Linden, RD Sheldon, GM Meers, EM Morris, JP Thyfault, MH Laughlin, RS Rector. A western diet high in fat,
sucrose, and cholesterol promotes advanced liver disease in sedentary, OLETF rats. Selected Oral Presentation.
MSSE Supplement 2015.
76. Y-Min Park, RS Rector, T Zidon, J Padilla, R Welly, RJ Scroggins, K Suzanne, SL Britton, LG Koch, GM Meers, FW
Booth, JP Thyfault, JA Kanaley, VJ. Vieira-Potter. Rats bred for high aerobic fitness are protected from ovariectomyinduced insulin resistance during euglycemic clamp. MSSE Supplement 2015.
R. Scott Rector
19
PRESENTATIONS AT LOCAL/REGIONAL/NATIONAL MEETINGS
2002
National Meeting, American College of Sports Medicine, June 2002. St. Louis, MO.
TR Thomas, JA Pellechia, GY Sun, RS Rector, and MH Laughlin. Effects of exercise training on the lipoprotein profile
of swine on an atherogenic diet.
2003
National Meeting, American College of Sports Medicine, June 2003. San Francisco, CA.
RS Rector, T.R. Thomas, Y. Liu, K.K. Henderson, D. Holiman, and M. Sturek. Postprandial lipemia after acute
exercise in Yucatan miniature swine.
st
Food for the 21 Century, September 2003. University of Missouri, Columbia, MO.
RS Rector, B.K. Smith, and T.R. Thomas. C-reactive protein is unaffected by exercise or n-3 fatty acid
supplementation in recreationally trained males.
Y. Liu, RS Rector, T.R. Thomas, J.A. Taylor, D.A. Holiman, K.K. Henderson, and M. Sturek. Lipoproteins during the
estrous cycle in swine.
RS Rector, T.R. Thomas, Y. Liu, K.K. Henderson, D. Holiman, and M. Sturek. Postprandial lipemia after acute
exercise in Yucatan miniature swine.
Central States Chapter, ACSM, October 2003. Kansas City, MO.
RS Rector, B.K. Smith, and T.R. Thomas. C-reactive protein is unaffected by exercise or n-3 fatty acid
supplementation in recreationally trained males.
RS Rector, T.R. Thomas, Y. Liu, K.K. Henderson, D. Holiman, and M. Sturek. Postprandial lipemia after acute
exercise in Yucatan miniature swine.
2004
Experimental Biology, April 2004. Washington DC.
RS Rector, EA Mokelke, NM Zafar, TR Thomas, M Sturek. Exercise training prevents elevation of C-reactive protein
in diabetic dyslipidemic Yucatan miniature swine.
KK Henderson, RS Rector, Y Liu, TR Thomas, JR Turk, MH Laughlin and M Sturek. Trans fat increases total/HDLcholesterol ratio in a porcine model of cardiovascular disease.
National Meeting, American College of Sports Medicine, June 2004, Indianapolis, IN
TS Altena, JL Michaelson, SD Ball, BL Giles, RS Rector, and TR Thomas. Lipoprotein subfraction changes after short
term continuous or intermittent exercise training.
RS Rector, B.K. Smith, G.Y. Sun, Y. Liu, and T.R. Thomas. C-reactive Protein and Secretory Phospholipase A2 are
Unaffected by Exercise or Omega-3 Fatty Acid Supplementation. Oral Presentation.
st
Food for the 21 Century, September 2004. University of Missouri, Columbia, MO.
RS Rector, E.J. Stites, B.L. Giles, B.W. Toedebusch, M.W. McClanahan, and T.R. Thomas. The effects of short-term
weight loss and subsequent regain on adipokines and other inflammatory markers.
B. L. Giles, RS Rector, B. W. Toedebusch, M. W. McClanahan, R.H. Cox, P. S. Hinton, and T. R. Thomas. The
effects of exercise training on maintenance of abdominal adiposity and lipoproteins during weight regain.
M.W. McClanahan, B.W. Toedebusch, B.L. Giles, RS Rector, P.S. Hinton, and T.R. Thomas. Effects of controlled
weight loss and regain, with exercise, on insulin resistance and thigh composition.
Y. Liu, T. R. Thomas, RS Rector, K. K. Henderson, M. H. Laughlin, and M. Sturek. Comparison of lipoproteins during
trans fatty acids diet and other high fat diets in swine.
Central States Chapter, ACSM, October 2004. Kansas City, MO.
RS Rector, E.J. Stites, B.L. Giles, B.W. Toedebusch, M.W. McClanahan, and T.R. Thomas. The effects of short-term
weight loss and subsequent regain on adipokines and other inflammatory markers.
R. Scott Rector
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M.W. McClanahan, B.W. Toedebusch, B.L. Giles, RS Rector, P.S. Hinton, and T.R. Thomas. Effects of controlled
weight loss and regain, with exercise, on insulin resistance and thigh composition.
B. L. Giles, RS Rector, B. W. Toedebusch, M. W. McClanahan, R.H. Cox, P. S. Hinton, and T. R. Thomas. The
effects of exercise training on maintenance of abdominal adiposity and lipoproteins during weight regain.
Y. Liu, T. R. Thomas, RS Rector, K. K. Henderson, M. H. Laughlin, and M. Sturek. Comparison of lipoproteins during
trans fatty acids diet and other high fat diets in swine.
2005
Experimental Biology, April 2005. San Diego, CA.
RS Rector, MW McClanahan, BL Giles, BW Toedebusch, and TR Thomas. Effects of short-term weight loss and
regain on measures of insulin resistance and the insulin-like growth factor axis.
National Meeting, American College of Sports Medicine, June 2005. Nashville, TN.
RS Rector, EJ Stites, BL Giles, BW Toedebusch, MW McClanahan, and TR Thomas. The effects of short-term weight
loss and partial weight regain on systemic inflammatory markers.
BL Giles, RS Rector, BW Toedebusch, MW McClanahan, RH Cox, PS Hinton, and TR Thomas. The effects of
exercise training on maintenance of abdominal adiposity and lipoproteins during weight regain.
Missouri Life Sciences Week, April 2005. University of Missouri, Columbia, MO.
KE Eklund, GD VanVickle, TR Thomas, RS Rector, Y Liu, M Sturek, and MH Laughlin. Effects of hypercholesterolemia
and exercise training on endothelium-dependent relaxation of left anterior descending coronary arteries from Ossabaw
swine.
st
Food for the 21 Century, September 2005. University of Missouri, Columbia, MO.
RS Rector, BL Guilford, JR Turk, and TR Thomas. Weight loss by aerobic training and energy restriction improves
measures of endothelial health in sedentary, overweight adults.
Y Liu, MA Linden, TR Jarvis, RS Rector, and TR Thomas. Omega-3 fatty acid supplementation and exercise training
attenuate postprandial lipemia in sedentary individuals.
MA Linden, Y Liu, RS Rector, T Altena, BK Smith, JQ Zhang, GG Ziogas and TR Thomas. The use of triglyceride
levels to estimate PPL measures through the use of multiple regression models.
RS Rector, VA Viele, PS Hinton, and TR Thomas. Aerobic Training Increases Markers of Bone Formation during
Short-Term Weight Loss.
TR Jarvis, MA Linden, Y Liu, RS Rector, and TR Thomas. Four weeks of omega-s fatty acid supplementation alone or
in combination with aerobic training does not improve measures of insulin resistance.
JE Peppers, RS Rector, LS Hillman, and PS Hinton. Serum TNF-α is increased in women with hypothalamic
menstrual disorders and in hormonal contraceptive users.
Central States Chapter, ACSM, October 2005. Kansas City, MO.
RS Rector, VA Viele, PS Hinton, and TR Thomas. Aerobic Training Increases Markers of Bone Formation During
Short-Term Weight Loss. Outstanding Poster-award winner.
PS Hinton, RS Rector, JE Peppers, LS Hillman. Serum TNF-α is increased in women with hypothalamic menstrual
disorders and in hormonal contraceptive users.
Y Liu, MA Linden, TR Jarvis, RS Rector, and TR Thomas. Omega-3 fatty acid supplementation and exercise training
attenuate postprandial lipemia in sedentary individuals.
2006
National Meeting, American College of Sports Medicine, Jun 2006. Denver, CO.
RS Rector, VA Viele, PS Hinton, and TR Thomas. Aerobic Training Increases Markers of Bone Formation During
Short-Term Weight Loss.
R. Scott Rector
21
Y. Liu, M.A. Linden, T.R. Jarvis, RS Rector, and T.R. Thomas. Omega-3 fatty acid supplementation and exercise
training attenuate postprandial lipemia in sedentary individuals.
National Institutes of Health. Pain Consortium, April, 2006. Bethesda, MD.
EA Dannecker, TR Thomas, RS Rector, and Y Liu. Measures and mechanisms of muscle pain in humans. National
Institutes of Health. Pain Consortium Symposium: Advances in Pain Research 2006.
st
Food for the 21 Century, October 3, 2006. University of Missouri, Columbia, MO.
RS Rector, R. Rogers, M. Ruebel, P.S. Hinton. Effects of weight-bearing and non-weight-bearing exercise on bone
mineral density and turnover in men.
RS Rector, Y. Liu, M.A. Linden, J. Garlow, and T.R. Thomas. Effects of omega-3 fatty acids and exercise on
inflammation and oxidative stress in sedentary individuals.
MA Linden, RS Rector, TS Altena, BK Smith, JQ Zhang, GG Ziogas, Y Liu, and TR Thomas. Estimating postprandial
lipemia using a single point triglyceride concentration.
ML Reubel, KS Herndon, RS Rector, JV Loethen, TR Thomas, and PS Hinton. Dietary fatty acid intake and
inflammatory markers in men and women.
Central States Chapter, ACSM, October 2006. Kansas City, MO.
RS Rector, R. Rogers, M. Ruebel, P.S. Hinton. Effects of weight-bearing and non-weight-bearing exercise on bone
mineral density and turnover in men. Outstanding Poster-award winner.
RS Rector, Y. Liu, M.A. Linden, J. Garlow, and T.R. Thomas. Effects of omega-3 fatty acids and exercise on
inflammation and oxidative stress in sedentary individuals.
M.A. Linden, RS Rector, T.S. Altena, B.K. Smith, J.Q. Zhang, G.G. Ziogas, Y. Liu, and T.R. Thomas. Estimating
postprandial lipemia using a single point triglyceride concentration.
2007
National Meeting, American College of Sports Medicine, Jun 2007. New Orleans, LA.
RS Rector, S. O. Warner, Y. Liu, P.S. Hinton, T.R. Thomas. Exercise and diet induced weight loss improves markers
of insulin sensitivity and oxidative stress. Oral Presentation.
M.A. Linden, RS Rector, T.S. Altena, B.K. Smith, J.Q. Zhang, G.G. Ziogas, Y. Liu, and T.R. Thomas. Estimating
postprandial lipemia using a single point triglyceride concentration.
S.O. Warner, RS Rector, Y. Liu, P.S. Hinton, D.R. Huyette, T.R. Thomas. Changes in Abdominal Adipose Tissue
Compartments with Changes in Body Weight. Oral Presentation.
S.P. Naples, S.O. Warner, J.P. Thyfault, RS Rector, Y. Liu, P.S. Hinton, T.R. Thomas. Diet- and Exercise-Induced
Weight Loss Lowers Intermuscular Fat and Low-Density Muscle Attenuation in Overweight Individuals.
J. Company, Y. Liu, RS Rector, S.O. Warner, T. R. Thomas. Scoring System for the Severity of the Metabolic
Syndrome.
National Meeting, Experimental Biology, April 2007. Washington DC.
Laye MJ, Borengasser SJ, RS Rector, Thyfault JT, Booth FW. Adipose tissue compensates to maintain whole body
insulin sensitivity 173 hours following the cessation of voluntary running in rats.
International Association for the Study of Pain Research Symposium: Fundamentals of Musculoskeletal Pain,
2007. Aalborg, Denmark
Dannecker, E. A., Robinson, M.E., Fillingim, R. B., Price, D. D., Sluka, K. A., Sayers, S. P., Thomas, T. R., RS
Rector, Liu, Y. Sex differences in delayed-onset muscle pain.
Central States Chapter, ACSM, October 2007. Springfield, MO.
S. Warner, RS Rector, MA Linden, Y Liu, TR Thomas. Alterations in abdominal adipose tissue distribution with
exercise during weight regain.
LM Bollinger, JP Thyfault, RS Rector, S Warner, PS Hinton, Y Liu, & TR Thomas. Effects of Exercise on PAI-1
during weight loss and Weight Regain.
R. Scott Rector
22
SJ Borengasser, SP Naples, EM Morris, RS Rector, GM Uptergrove, JP Thyfault. A high fat diet increases metabolic
risk in rats selectively bred for low aerobic capacity.
JV Loethen, RS Rector, ML Ruebel, TR Thomas, and PS Hinton. Effects of weight-bearing and non-weight bearing
exercise on serum markers of bone turnover during short-term weight loss in overweight adult women. Oral
Presentation.
R Rogers, RS Rector, M Ruebel, PS Hinton. Mechanism of increased bone mineral density in resistance-trained male
athletes compared with runners and cyclists.
American Association for the Study of Liver Diseases, November 2007. National Meeting, Boston, MA.
RS Rector, JP Thyfault, RT Morris, MJ Laye, SJ Borengasser, FW Booth, and JA Ibdah. Daily exercise increases
hepatic fatty acid oxidation and prevents steatosis in Otsuka Long-Evans Tokushima Fatty (OLETF) rats. Hepatology
46(4) Suppl: 758A, 2007. Abstract 1170.
JP Thyfault, RS Rector, Uptergrove, GM, Morris, EM, Wei, Y, Laye, MJ, Clark, SE, Koch, LG, Britton, SL, and JA
Ibdah. Rats selectively bred for low endurance capacity display evidence for the development of NAFLD at an early
age. Hepatology 46(4) Suppl: 308A, 2007. Abstract 161. Oral Presentation.
2008
Diabetes Mellitus, Insulin Action and Resistance. Keystone Symposia, January 2008. Breckenridge, CO.
RS Rector, JP Thyfault, MJ Laye, SJ Borengasser, RT Morris, FW Booth, and JA Ibdah
Short-term cessation of daily physical activity causes a loss of mitochondrial oxidative capacity and an increase in key
lipogenic intermediates in the livers of Otsuka Long-Evans Tokushima Fatty (OLETF) rats.
JP Thyfault, S Naples, SJ Borengasser, RS Rector, GM Uptergrove, EM Morris, L Koch, S Britton, and JA Ibdah. The
impact of a high fat diet on skeletal muscle mitochondrial oxidative capacity and insulin sensitivity of rats selectively
bred for high and low endurance exercise capacity.
Nutrition and Exercise Emphasis Week, University of Missouri, March 2008
Laye MJ, Borengasser SJ, RS Rector, Uptergrove G, Naples S, Thyfault JT, Booth FW. Cessation of Daily Physical
Activity Leads to Tissue Specific Changes in Palmitate Oxidation in Male Rats.
CR Mikus, SJ Borengasser, RS Rector, SP Naples, GM Uptergrove, ML Ruebel, MJ Laye, FW Booth, JA Ibdah, and JP
Thyfault. Daily physical activity prevents aging and obesity induced skeletal muscle insulin resistance in the OLETF rat.
SP Naples, RS Rector, GM Uptergrove, SJ Borengasser, CR Mikus, KA Geter, FW Booth, JP Thyfault, and JA Ibdah.
Daily Physical Activity Enhances Mitochondrial Fatty Acid Oxidative Capacity in Skeletal Muscle and Liver of OLETF
Rats.
RS Rector, JP Thyfault, MJ Laye, SJ Borengasser, RT Morris, FW Booth, and JA Ibdah. Short-term cessation of daily
physical activity causes a loss of mitochondrial oxidative capacity and an increase in key lipogenic intermediates in the
livers of Otsuka Long-Evans Tokushima Fatty (OLETF) rats.
M Ruebel, SP Naples, SJ Borengasser, MJ Laye, RS Rector, Grace M Uptergrove, E M Morris, LG Koch, SL Britton, JA
Ibdah, and JP Thyfault. Rats selectively bred for high or low aerobic running capacity display phenotypical differences
in fat pad weight and cell volume.
JP Thyfault, RS Rector, GM Uptergrove, EM Morris, Y Wei, MJ Laye, SE Clark, LG Koch, SL Britton, and JA Ibdah.
Rats selectively bred for low endurance capacity display evidence for the development of NAFLD at an early age.
LM Bollinger, JP Thyfault, RS Rector, SO Warner, PS Hinton, Y Liu, and TR Thomas. Effects of exercise on
plasminogen activator inhibitor-1 during weight loss and weight regain.
SJ Borengasser, SP Naples, RS Rector, CA Mikus, GM Uptergrove, EM Morris, LG Koch, SL Britton, JA Ibdah, and JP
Thyfault. Skeletal muscle mitochondrial oxidative capacity and metabolic responses to a high fat diet or gaining in rats
bred for high and low aerobic capacity.
JV Loethen, RS Rector, ML Ruebel, TR Thomas, and PS Hinton. Effects of weight-bearing and non-weight bearing
exercise on markers of bone turnover during short-term weight loss in overweight premenopausal women.
R. Scott Rector
23
CA Peterson, S Ring, J Loethen, RS Rector, T Thomas, PS Hinton. Vitamin D status is unaltered by mild weight
reduction in obese premenopausal women.
R Rogers, RS Rector, M Ruebel, PS Hinton. Mechanism of increased bone mineral density in resistance-trained male
athletes compared with runners and cyclists.
S. Warner, RS Rector, MA Linden, Y Liu, TR Thomas. Alterations in abdominal adipose tissue distribution with
exercise during weight regain.
Experimental Biology, National Meeting, April 2008. San Diego, CA.
CA Peterson, S Ring, J Loethen, RS Rector, TR Thomas, PS Hinton. Vitamin D status is unaltered by mild weight
reduction in obese premenopausal women. FASEB J 2008.
American College of Sports Medicine, National Meeting, Jun 2008. Indianapolis, IN
R Rogers, RS Rector, M Ruebel, M Widzer, PS Hinton. Lean body mass predicts bone mineral density in male
resistance-trained athletes.
Digestive Disease Week, May 2008. National Meeting, San Diego, CA.
RS Rector, JP Thyfault, MJ Laye, RT Morris, SJ Borengasser, GM Uptergrove, FW Booth, and JA Ibdah. Physical
activity and short-term inactivity modulate hepatic fatty acid oxidation and lipogenesis proteins in Otsuka Long-Evans
Tokushima Fatty (OLETF) rats. Poster of Distinction Award Winner.
American Diabetes Association, June 2008, San Francisco, CA.
Borengasser SJ, Naples SP, Rector RS, Mikus CA, Uptergrove GM, Morris EM, Koch LG, Britton SL, Ibdah JA and
Thyfault JP. Skeletal muscle mitochondrial oxidative capacity and metabolic responses to a high fat diet or aging in rats
bred for high and low aerobic capacity. Diabetes, 57 (supplement 1). 1539P, 2008.
World Congress on Pain, August 2008, Scotland
Dannecker EA, Liu Y, RS Rector, Thomas TR, Fillingim RB, Robinson ME.
Sex Differences in the Symptoms and Signs of Exercise-Induced Muscle Damage
Central States Chapter, ACSM, October 2008. Kansas City, MO.
Borengasser, SJ, Rector, RS, Naples, SP, Uptergrove, GM, Morris, EM, Wei,Y, Ridenhour, SE, Fritsche, KL, Koch,
LG, Britton, SL, JA Ibdah, and JP Thyfault. Hepatic steatosis and metabolic responses to high fat feeding in female
rats breed for high and low aerobic capacity.
LM Bollinger, SO Warner, MA Linden, MA Ruebel, Y Liu, RS Rector, J Fresen, JA Potteiger, SP Sayers, JP Thyfault,
& TR Thomas. A proposed scoring system for quantification of metabolic syndrome severity.
American Association for the Study of Liver Diseases, November 2008. National Meeting, San Francisco, CA.
NM Szary, GM Uptergrove, SP Naples, S Ridenhour, R Gitaan, RS Rector, JP Thyfault, SD Shukla, JA Ibdah. Mice
heterozygous for a defect in mitochondrial trifunctional protein are susceptible for development of hepatic steatosis
when fed a diet rich in fat with and without ethanol. Abstract 1166, Hepatology 48(4) Suppl, October 2008.
JP Thyfault, RS Rector, SP Naples, GM Uptergrove, SJ Borengasser, EM Morris, Y Wei, S Ridenhour, KL Fritsche,
LG Koch, SL Britton, JA Ibdah. Hepatic steatosis and metabolic responses to high fat feeding in female rats bred for
high and low aerobic capacity. Abstract 1181, Hepatology 48(4) Suppl, October 2008.
RS Rector, JP Thyfault, GM Uptergrove, SP Naples, SJ Borengasser, CR Mikus, MJ Laye, MH Laughlin, FW
Booth, and JA Ibdah. Effects of daily physical activity on the natural history of NAFLD and insulin resistance in
Otsuka Long-Evans Tokushima Fatty (OLETF) rats. Abstract 1203, Hepatology 48(4) Suppl, October 2008.
2009
Cardiovascular Day, University of Missouri, February 2009.
CR Mikus, RS Rector, PK Thorne, EM Morris, FW Booth, JA Ibdah, MH Laughlin, JP Thyfault. Exercise maintains
microvascular reactivity to insulin in skeletal muscle arterioles of hyperphagic rats prone to obesity.
Experimental Biology, National Meeting, April 2009. New Orleans, LA.
CR Mikus, RS Rector, PK Thorne, EM Morris, FW Booth, JA Ibdah, MH Laughlin, JP Thyfault. Exercise maintains
microvascular reactivity to insulin in skeletal muscle arterioles of hyperphagic rats prone to obesity.
R. Scott Rector
24
American College of Sports Medicine, National Meeting, May 2009. Seattle, WA.
Session Title: Prevention of Fatty Liver Disease through Lifestyle Modification: From Cellular Mechanisms to Clinical
Applications. John P. Thyfault and RS Rector, co-chairs.
Oral Presentation Title: Potential Mechanisms Mediating Exercise-Associated Attenuation of Fatty Liver Disease. RS
Rector
TR Thomas, SO Warner, Y Liu, MA Linden, PS Hinton, KC Dellsperger, A Chockalingham, AT Whaley-Connell, RS
Rector, JP Thyfault, DR Huyette. Exercise and the Metabolic Syndrome with Weight Regain.
Digestive Disease Week, May 2009. National Meeting, Chicago, IL.
RS Rector, JP Thyfault, GM Uptergrove, EM Morris, SP Naples, SJ Borengasser, CR Mikus, MJ Laye, MH Laughlin,
FW Booth, JA Ibdah. Loss of mitochondrial content and function contribute to the natural history of nonalcoholic fatty
liver disease in a hyperphagic obese rodent model.
A Choudhary, NM Szary, ML Bechtold, SR Puli, RS Rector, JP Thyfault, JA Ibdah. Insulin sensitizers for the
management of non-alcoholic fatty liver disease: a meta-analysis of randomized controlled trials
Nutrition and Exercise Emphasis Week, University of Missouri, March 31, 2009
RS Rector, JP Thyfault, GM Uptergrove, EM Morris, SP Naples, SJ Borengasser, CR Mikus, MJ Laye, MH Laughlin,
FW Booth, JA Ibdah. Loss of mitochondrial content and function contribute to the natural history of nonalcoholic fatty
liver disease in a hyperphagic obese rodent model.
GM Uptergrove, RS Rector, MJ Laye, SO Warner, SP Naples, AL Perretta, MH Laughlin, JP Thyfault, FW Booth, and
JA Ibdah. Changes in visceral adipose tissue mitochondrial content with type 2 diabetes and daily voluntary wheel
running in Otsuka Long-Evans Tokushima Fatty rats.
Y Liu, SO Warner, MA Linden, RS Rector, PS Hinton, AT Whaley-Connell, A Chockalingam, KC Dellsperger, and TR
Thomas. Effects of aerobic exercise training during weight regain on physical health
NM Szary, GM Uptergrove, RS Rector, S Ridenhour, JP Thyfault, SL Britton, LG Koch, ML Bechtold, SD Shukla, JA
Ibdah. High Intrinsic Aerobic Capacity Does Not Protect Against Hepatic Steatosis from Chronic Ethanol Intake
American Association for the Study of Liver Diseases, November 2009. National Meeting, Boston, MA.
RS Rector, GM Uptergrove, RS Gitan, and JA Ibdah. Daily exercise attenuates the development of hepatic steatosis
in mice heterozygous for a mitochondrial trifunctional protein defect.
NM Szary, GM Uptergrove, RS Rector, S Ridenhour, JP Thyfault, SL Britton, LG Koch, ML Bechtold, SD Shukla, and
JA Ibdah. High Intrinsic Aerobic Capacity Does Not Protect Against Hepatic Steatosis From Chronic Ethanol Intake.
Central States Chapter, ACSM, November 2009. Columbia, MO.
RS Rector. Negative consequences of physical inactivity on liver health and disease development. Invited Talk.
SJ Borengasser, RS Rector, GM Uptergrove, EM Morris, JL Libla, FW Booth, KL Fritsche, JA Ibdah, and JP Thyfault.
Exercise and omega-3 fatty acids as treatments for nonalcoholic fatty liver disease.
A Choudhary, NM Szary, ML Bechtold, SR Puli, RS Rector, JP Thyfault, JA Ibdah. Insulin sensitizers for the
management of non-alcoholic fatty liver disease: a meta-analysis of randomized controlled trials.
GM Uptergrove, RS Rector, SJ Borengasser, CR Mikus, EM Morris, SP Naples, MJ Laye, MH Laughlin, FW Booth, JA
Ibdah, and JP Thyfault. Skeletal muscle mitochondrial content and fatty acid oxidation in hyperphagic OLETF rats.
2010
Life Sciences Summit, Kansas City, MO March 8-9, 2010
RS Rector, GM Uptergrove, FW Booth, JP Thyfault, and JA Ibdah. Interdisciplinary Approach to Examine the Effects
of Lifestyle Modifications on Nonalcoholic Fatty Liver Disease.
EM Morris, RS Rector, SL Britton, JA Ibdah, and JP Thyfault. Translational Approach to Examine the Importance of
Aerobic Fitness on Nonalcoholic Fatty Liver Disease.
R. Scott Rector
25
Nutrition and Exercise Research Week, University of Missouri, April 7, 2010
SJ Borengasser, RS Rector, GM Uptergrove, EM Morris, JL Libla, FW Booth, KL Fritsche, JA Ibdah, and JP Thyfault.
Exercise and omega-3 fatty acids as treatments for nonalcoholic fatty liver disease.
GM Uptergrove, RS Rector, SJ Borengasser, CR Mikus, EM Morris, SP Naples, MJ Laye, MH Laughlin, FW Booth, JA
Ibdah, and JP Thyfault. Skeletal muscle mitochondrial content and fatty acid oxidation in hyperphagic OLETF rats.
RS Rector, GM Uptergrove, RS Gitan, and JA Ibdah. Daily exercise attenuates the development of hepatic steatosis
in mice heterozygous for a mitochondrial trifunctional protein defect.
RS Rector, GM Uptergrove, FW Booth, JP Thyfault, and JA Ibdah. Interdisciplinary Approach to Examine the Effects
of Lifestyle Modifications on Nonalcoholic Fatty Liver Disease.
EM Morris, RS Rector, SL Britton, JA Ibdah, and JP Thyfault. Translational Approach to Examine the Importance of
Aerobic Fitness on Nonalcoholic Fatty Liver Disease.
EA Dannecker, Y Liu, RS Rector, TR Thomas, C Leeuwenburgh, and BK Ray. Effect of intermittent fasting for five
consecutive days on exercise-induced muscle damage in humans.
Veteran Administration Research Day- HSTMVH- Columbia, MO, April 29, 2010
SJ Borengasser, RS Rector, GM Uptergrove, EM Morris, JL Libla, FW Booth, KL Fritsche, JA Ibdah, and JP Thyfault.
Exercise and omega-3 fatty acids as treatments for nonalcoholic fatty liver disease.
RS Rector, GM Uptergrove, FW Booth, JP Thyfault, and JA Ibdah. Interdisciplinary Approach to Examine the Effects
of Lifestyle Modifications on Nonalcoholic Fatty Liver Disease.
EM Morris, RS Rector, SL Britton, JA Ibdah, and JP Thyfault. Translational Approach to Examine the Importance of
Aerobic Fitness on Nonalcoholic Fatty Liver Disease.
RS Rector, GM Uptergrove, RS Gitan, and JA Ibdah. Daily exercise attenuates the development of hepatic steatosis
in mice heterozygous for a mitochondrial trifunctional protein defect.
American College of Sports Medicine, National Meeting, June 2010. Baltimore, MD.
EA Dannecker, Y Liu, RS Rector, TR Thomas, C Leeuwenburgh, and BK Ray. Effect of intermittent fasting for five
consecutive days on exercise-induced muscle damage in humans.
American Diabetes Association, June 2010, Orlando, CA.
SJ Borengasser, RS Rector, GM Uptergrove, EM Morris, JL Libla, FW Booth, KL Fritsche, JA Ibdah, and JP Thyfault.
Exercise and omega-3 fatty acids as treatments for nonalcoholic fatty liver disease. Diabetes, 2010
American Association for the Study of Liver Diseases, October 2010, National Meeting, Boston, MA.
2010 SIG Symposia-- Genetics and Environment in the Progression of NAFLD. RS Rector. Exercise and outcomes of
fatty liver disease- Invited Talk.
RS Rector, GM Uptergrove, EM Morris, SJ Borengasser, MH Laughlin, FW Booth, JP Thyfault, and JA Ibdah.
Attenuation of weight gain through daily exercise versus caloric restriction and prevention of nonalcoholic fatty liver
disease in hyperphagic OLETF rats. Hepatology, 2010
2011
Type 2 Diabetes, Insulin Resistance and Metabolic Dysfunction. Keystone Symposia, January 2011. Keystone,
CO.
RS Rector, GM Uptergrove, EM Morris, SJ Borengasser, MH Laughlin, FW Booth, JP Thyfault, and JA Ibdah.
Attenuation of weight gain through daily exercise versus caloric restriction and prevention of nonalcoholic fatty liver
disease in hyperphagic OLETF rats.
GM Uptergrove, RS Rector, and JA Ibdah. Daily exercise rescues the hepatic phenotype of mice heterozygous for a
fatty acid oxidation defect.
R. Scott Rector
26
EM Morris, GM Uptergrove, G Powell, RS Rector, DM Muoio, JA Ibdah, and JP Thyfault. High intrinsic aerobic fitness,
daily exercise, and overexpression of PGC-1α result in similar phenotype for fatty acid oxidation in primary
hepatocytes.
CR Mikus, BT Roseguini, GM Uptergrove, EM Morris, RS Rector, JA Ibdah, MH Laughlin, JP Thyfault. Microvascular
reactivity to insulin in obese rats is selectively improved in arterioles of skeletal muscles recruited during voluntary
wheel running.
Cardiovascular Day, University of Missouri, February 2011.
CR Mikus, BT Roseguini, GM Uptergrove, EM Morris, RS Rector, JA. Ibdah, JP Thyfault, and MH Laughlin. Chronic
wheel running selectively augments insulin-stimulated vasodilation in arterioles from the white gastrocnemius.
Nutrition and Exercise Research Week, University of Missouri, March 22, 2011
MN Khan, ML Ruebel, GM Uptergrove, RT Pickering, L Ortinau, JW Perfield II, and RS Rector. Altered Hepatic Lipid
Metabolism Contributes to Nonalcoholic Fatty Liver Disease in Leptin-Deficient Ob/Ob Mice.
CR Mikus, BT Roseguini, GM Uptergrove, EM Morris, RS Rector, JA. Ibdah, JP Thyfault, and MH Laughlin. Chronic
wheel running selectively augments insulin-stimulated vasodilation in arterioles from the white gastrocnemius.
EM Morris, GM Uptergrove, G Powell, RS Rector, DM Muoio, JA Ibdah, and JP Thyfault. High intrinsic aerobic fitness,
daily exercise, and overexpression of PGC-1α result in similar phenotype for fatty acid oxidation in primary
hepatocytes.
BT Pape, GM Uptergrove, ML Ruebel, MH Laughlin, FW Booth, JP Thyfault, JA Ibdah and RS Rector. Effects of Four
Weeks of Exercise Cessation on Hepatic Steatosis Development and Hepatic Lipid Metabolism in Hyperphagic OLETF
Rats.
GM Uptergrove, RS Rector, and JA Ibdah. Daily exercise rescues the hepatic phenotype of mice heterozygous for a
fatty acid oxidation defect.
Experimental Biology, Washington DC, April 9-13, 2011
CR Mikus, BT Roseguini, GM Uptergrove, EM Morris, RS Rector, JA. Ibdah, JP Thyfault, and MH Laughlin. Chronic
wheel running selectively augments insulin-stimulated vasodilation in arterioles from the white gastrocnemius. FASEB
J 2011.
Veteran Administration Research Day- HSTMVH- Columbia, MO, May 4, 2011
GM Uptergrove, RS Rector, and JA Ibdah. Daily exercise rescues the hepatic phenotype of mice heterozygous for a
fatty acid oxidation defect.
MN Khan, ML Ruebel, GM Uptergrove, RT Pickering, L Ortinau, JW Perfield II, and RS Rector. Altered Hepatic Lipid
Metabolism Contributes to Nonalcoholic Fatty Liver Disease in Leptin-Deficient Ob/Ob Mice.
GM Uptergrove, RS Rector, and JA Ibdah. Daily exercise rescues the hepatic phenotype of mice heterozygous for a
fatty acid oxidation defect.
The Obesity Society Meeting, Orlando, FL, Oct 1, 2011
RS Rector, MN Khan, ML Ruebel, GM Uptergrove, RT Pickering, L Ortinau, and JW Perfield II. Altered Hepatic Lipid
Metabolism Contributes to Nonalcoholic Fatty Liver Disease in Leptin-Deficient Ob/Ob Mice.
Central States Chapter, ACSM, Kansas City, MO, October 2011.
JA Fletcher, GM Meers, JA Ibdah, JP Thyfault, and RS Rector. Daily exercise and caloric restriction impact fibroblast
growth factor-21 in hyperphagic OLETF rats.
Health Sciences Research Day, Columbia, MO, November 3, 2011
JA Fletcher, GM Meers, JA Ibdah, JP Thyfault, and RS Rector. Daily exercise and caloric restriction impact fibroblast
growth factor-21 in hyperphagic OLETF rats.
American Association for the Study of Liver Diseases, November 4-8, 2011, National Meeting, San Francisco, CA.
EM Morris, GM Uptergrove, G Powell, RS Rector, JA Ibdah, and JP Thyfault. Daily exercise results in increased
hepatic fatty acid oxidation and mitochondrial content in rat primary hepatocytes.
R. Scott Rector
27
RS Rector, S Ridenhour, GM Uptergrove, and JA Ibdah. Hepatic insulin resistance in mice heterozygous for a
mitochondrial trifunctional protein defect. Presidential Plenary Session Oral Presentation.
2012
Nutrition and Exercise Research Week, University of Missouri, March 15, 2012
JA Fletcher, GM Meers, JA Ibdah, JP Thyfault, and RS Rector. Daily exercise and caloric restriction impact fibroblast
growth factor-21 in hyperphagic OLETF rats.
MA Linden, GM Meers, NT Jenkins, JA Ibdah, JP Thyfault, and RS Rector. Consequences of a return to physical
inactivity on adiposity, glycemic control, systemic inflammation, and hepatic steatosis in hyperphagic OLETF rats.
Veteran Administration Research Day- HSTMVH- Columbia, MO, April 26, 2012
MA Linden, GM Meers, NT Jenkins, JA Ibdah, JP Thyfault, and RS Rector. Consequences of a return to physical
inactivity on adiposity, glycemic control, systemic inflammation, and hepatic steatosis in hyperphagic OLETF rats.
JA Fletcher, GM Meers, JA Ibdah, JP Thyfault, and RS Rector. Daily exercise and caloric restriction impact fibroblast
growth factor-21 in hyperphagic OLETF rats.
American College of Sports Medicine, National Meeting, May 2012. San Francisco, CA.
DJ Oberlin, CR Mikus, ML Kearney, JA Fletcher, PS Hinton, JA Kanaley, RS Rector, HJ Leidy, JP Thyfault. A single
exercise bout does not improve glycemic control in volunteers with type 2 diabetes. MSSE Supplement 44(5):2012.
JA Fletcher, GM Meers, JA Ibdah, JP Thyfault, and RS Rector. Daily exercise and caloric restriction impact fibroblast
growth factor-21 in hyperphagic OLETF rats. MSSE Supplement 44(5): 2012.
Integrative Physiology of Exercise Meeting, October 10-13, 2012, Westminster, CO
NT Jenkins, J Padilla, JS Martin, JM Crissey, JP Thyfault, RS Rector, and M Laughlin. Differential vasodilator effects
of insulin between gastrocnemius and soleus muscle feed arteries: Role of endothelin-1
EM Morris, GME Meers, TW Liu, ML Kearney, AL Blandon, JA Fletcher, RS Rector, JP Thyfault. High intrinsic aerobic
capacity is associated with greater liver fatty acid oxidation adaptability
JP Thyfault, EM Morris, RS Rector. Intrinsic Fitness and Exercise Prevent Hepatic Lipotoxicity
RG Toedebusch, KD Wells, FW Booth, RS Rector. Molecular signatures of adipose tissue in an Ossabaw swine
model of childhood obesity using transcriptome analysis.
JA Fletcher, GM Meers, MA Linden, ML Kearney, EM Morris, JP Thyfault, RS Rector. Impact of voluntary wheel
running and treadmill exercise training on hepatic mitochondrial metabolism and function
Central States Chapter, ACSM, Columbia, MO, October 2012.
JM Crissey, J Padilla, NT Jenkins, JS Martin, RS Rector, JP Thyfault, and MH Laughlin. Effects of exercise and
metformin on insulin-induced vasodilation in skeletal muscle Arterioles of OLETF Rats
JA Fletcher, GME Meers, MA Linden, ML Kearney, EM Morris, JP Thyfault, RS Rector. Impact of voluntary wheel
running and treadmill exercise training on hepatic mitochondrial metabolism and function
NT Jenkins, J Padilla, JS Martin, JM Crissey, JP Thyfault, RS Rector, and M Laughlin. Differential vasodilator effects
of insulin between gastrocnemius and soleus muscle feed arteries: Role of endothelin-1
MA Linden, GM Meers, KM Kanosky, JA Fletcher, and RS Rector. A return to ad libitum feeding following caloric
restriction on hepatic steatosis in OLETF rats.
RD Sheldon, GM Meers, MH Laughlin, RS Rector. Reduced hepatic eNOS phosphorylation in sedentary hyperphagic
OLETF rats is prevented by voluntary wheel running.
Health Sciences Research Day, Columbia, MO, November 15, 2012
JA Fletcher, GME Meers, MA Linden, ML Kearney, EM Morris, JP Thyfault, RS Rector. Impact of voluntary wheel
running and treadmill exercise training on hepatic mitochondrial metabolism and function
R. Scott Rector
28
MA Linden, GM Meers, KM Kanosky, JA Fletcher, and RS Rector. A return to ad libitum feeding following caloric
restriction on hepatic steatosis in OLETF rats.
RD Sheldon, GM Meers, MH Laughlin, RS Rector. Reduced hepatic eNOS phosphorylation in sedentary hyperphagic
OLETF rats is prevented by voluntary wheel running.
KL Stromsdorfer, LC Ortinau, M Ruebel, GME Meers, KJ Nickelson, MA Linden, T-W Liu, JA Ibdah, FW Booth, and RS
Rector. Modeling childhood obesity in juvenile Ossabaw swine
American Association for the Study of Liver Diseases, November 9-13, 2012, National Meeting, Boston, MA.
RS Rector, GM Meers, JA Fletcher, MA Linden, MH Laughlin, FW Booth, JP Thyfault, JA Ibdah. Moderate vs.
vigorous intensity exercise training in the treatment of type 2 diabetes and nonalcoholic fatty liver in the hyperphagic,
obese OLETF rat.
2013
Life Sciences Week, Columbia, MO April 2013
RD Sheldon, GM Meers, MH Laughlin, and RS Rector. Reduced hepatic enos phosphorylation in sedentary
hyperphagic oletf rats is prevented by Voluntary wheel running
T Tan, GM Meers, JA Fletcher, MA Linden, MH Laughlin, FW Booth, JP Thyfault, JA Ibdah, and RS Rector.
Comparing moderate vs. vigorous intensity exercise training in the treatment of nonalcoholic fatty liver in the
hyperphagic, obese OLETF rat
KL Stromsdorfer, LC Ortinau, ML Ruebel, GM Meers, KJ Nickelson, MA Linden, T-W Liu, JA Ibdah, FW Booth, JW
Perfield II, and RS Rector. Modeling Childhood Obesity in juvenile Ossabaw Swine.
Experimental Biology, Boston, MA, April 18-23, 2013
SB Bender, JW Davis, RS Rector, MH Laughlin, JR Sowers. Characterization of the coronary vascular transcriptome
in a rat model of metabolic syndrome. FASEB J 2013.
CA Emter, RS Rector, CP Baines, KD Ford, DA Ford. Chronic Interval Exercise Modifies the Myocardial Lipid Profile
in a Miniature Swine Model of Heart Failure with Preserved Ejection Fraction. FASEB J 2013. Oral Presentation
S Lee, FW Booth, RS Rector, MA Hill. Obesity leads to altered vasomotor function in juvenile Ossabaw pigs. FASEB
J 2013.
MA Linden, GM Meers, JA Fletcher, S Siddique, MH Laughlin, FW Booth, JA Ibdah, JP Thyfault, and RS Rector.
Metformin, Aerobic Exercise, and the Combination in the Treatment of Type 2 Diabetes and NAFLD in OLETF rats.
FASEB J 2013. Oral Presentation
Veteran Administration Research Day- HSTMVH- Columbia, MO, May 13, 2013
JA Fletcher, GM Meers, MA Linden, ML Kearney, EM Morris, JP Thyfault, and RS Rector. Impact of voluntary wheel
running in combination with overnight fasting on hepatic mitochondrial metabolism and function.
MA Linden, GM Meers, JA Fletcher, Sameer Siddique, MH Laughlin, FW Booth, JA Ibdah, JP Thyfault, and RS
Rector. Metformin, Aerobic Exercise, and the Combination in the Treatment of Type 2 Diabetes and NAFLD in OLETF
rats.
RD Sheldon, GM Meers, MH Laughlin, RS Rector. Effects of NAFLD, type 2 diabetes, and exercise on basal hepatic
eNOS and Akt activation in hyperphagic OLETF rats.
T Tan, GM Meers, JA Fletcher, MA Linden, MH Laughlin, FW Booth, JP Thyfault, JA Ibdah, and RS Rector.
Comparing moderate vs. vigorous intensity exercise training in the treatment of nonalcoholic fatty liver in the
hyperphagic, obese OLETF rat.
KL Stromsdorfer, LC Ortinau, ML Ruebel, GM Meers, KJ Nickelson, MA Linden, T-W Liu, JA Ibdah, FW Booth, JW
Perfield II, and RS Rector. Modeling childhood obesity in juvenile Ossabaw swine.
American College of Sports Medicine Meeting, Indianapolis, IN, May 29-June 1, 2013.
Ryan D. Sheldon, Grace M. Meers, M. Harold Laughlin, R. Scott Rector. Reduced Hepatic eNOS Phosphorylation in
Sedentary Hyperphagic OLETF Rats is Prevented by Voluntary Wheel Running. Med Sci Sport Exerc Suppl 2013
R. Scott Rector
29
J Padilla, NT Jenkins, S Lee, H Zhang, J Cui, MY Zuidema, C Zhang (deceased), MA Hill, JW Perfield II, JA Ibdah, FW
Booth, JW Davis, MH Laughlin, RS Rector. Juvenile obesity in Ossabaw swine produces artery-specific transcriptional
changes. Med Sci Sport Exerc Suppl 2013
MA Linden, GM Meers, KM Kanosky, JA Fletcher, MH Laughlin, JP Thyfault, and RS Rector. Protection against
NAFLD development following prior physical activity versus caloric restriction in OLETF rats. Med Sci Sport Exerc
Suppl 2013
NT Jenkins, J Padilla, RS Rector, and MH Laughlin. Physical activity increases β-adrenergic and natriuretic peptide
receptor mRNAs in adipose tissue of OLETF rats. Med Sci Sport Exerc Suppl 2013
JA Fletcher, GM Meers, MA Linden, ML Kearney, EM Morris, JP Thyfault, and RS Rector. Impact of voluntary wheel
running in combination with overnight fasting on hepatic mitochondrial metabolism and function. Med Sci Sport Exerc
Suppl 2013
American Diabetes Association, Chicago, IL, June 22-25, 2013
EM Morris, GME Meers, JA Fletcher, ML Kearney, TW Liu, AM Hinds, RS Rector, JA Ibdah, LG Koch, SL Britton, JP
Thyfault. High Intrinsic Aerobic Capacity Prevents Development of Hepatic Steatosis Following an Acute High-Fat
Diet. Diabetes 62:Suppl 1, 2013.
Central States Chapter, ACSM, Warrensburg, MO, October 2013.
RD Sheldon, J Padilla, MH Laughlin, RS Rector. Nitric oxide synthase inhibition does not alter heptatic mitochondrial
function in nonalcoholic fatty liver disease
MA Linden, KT Lopez, JA Fletcher, GM Meers, S Siddique, EM Morris, MH Laughlin, JR Sowers, JP Thyfault, JA
Ibdah, and RS Rector. Combination therapy of metformin and caloric restriction in the treatment of type 2 diabetes
and NAFLD in OLETF rats.
Health Sciences Research Day, Columbia, MO, November 15, 2013
MA Linden, KT Lopez, JA Fletcher, GM Meers, S Siddique, EM Morris, MH Laughlin, JR Sowers, JP Thyfault, JA
Ibdah, and RS Rector. Combination therapy of metformin and caloric restriction in the treatment of type 2 diabetes
and NAFLD in OLETF rats.
JA Fletcher, GM Meers, MA Linden, ML Kearney, EM Morris, JP Thyfault, and RS Rector. Impact of voluntary wheel
running in combination with overnight fasting on hepatic mitochondrial metabolism and function.
American Association for the Study of Liver Diseases, November 9-13, 2013, National Meeting, Washington DC.
EM Morris, MR Jackman, GC Johnson, GME Meers, J Houser, LG Koch, SL Britton, RS Rector, JA Ibdah, PS
MacLean, JP Thyfault. High intrinsic aerobic capacity protects against 3-day high fat diet induced hepatic steatosis
through increased fat utilization and energy expenditure.
2014
Life Sciences Week, Columbia, MO April 2014
L Taylor, AN Blaize, KE Karlin, GM Meers, KM Kanosky, SS Donkin, SC Newcomer, RS Rector. Maternal exercise
during pregnancy attenuates high fat diet induced nonalcoholic fatty liver disease in mature male offspring.
RD Sheldon, J Padilla, N Jenkins, MH Laughlin, RS Rector. Nitric oxide synthase inhibition exacerbates liver injury in
an obese rat model of NAFLD.
Experimental Biology, San Diego, CA, April, 2014
RD Sheldon, J Padilla, N Jenkins, MH Laughlin, RS Rector. Nitric oxide synthase inhibition exacerbates liver injury in
an obese rat model of NAFLD.
NT Jenkins, J Padilla, PK Thorne, JS Martin, RS Rector, JW Davis, MH Laughlin. Transcriptome-Wide RNA
Sequencing Analysis of Rat Skeletal Muscle Feed Arteries: Impact of Obesity.
MA Linden*, KT Lopez, JA Fletcher, GM Meers, S Siddique, EM Morris, JM Crissey, ML Kearney, MH Laughlin, JR
Sowers, JP Thyfault, JA Ibdah, and RS Rector. Improved efficacy of metformin therapy when combined with caloric
restriction in the treatment of type 2 diabetes and NAFLD in OLETF rats.
R. Scott Rector
30
RJ Scroggins, J Padilla, R Welly, D Jackson, TN Smith, VJ Vieira-Potter, RS Rector. Obesity-prone female ossabaw
pigs are protected against western diet-induced adipose tissue inflammation and immune cell infiltration.
HT Yang, RS Rector, PK Thorne, X Chen, MH Laughlin. Increases in rat adipose blood flows following bolus
intraperitoneal injection of glucose.
Veteran Administration Research Day- HSTMVH- Columbia, MO, May 6, 2014
MA Linden, RD Sheldon, JA Fletcher, GM Meers, MH Laughlin, JP Thyfault, and RS Rector. Exercise of different
intensities alter hepatic mRNA expression of M1/M2 polarization markers in OLETF rats.
JA Fletcher, GN Ruegsegger, KM Kanosky, FW Booth, JP Thyfault, and RS Rector. Hepatic mitochondrial content
and function in rats selectively bred for high vs. low voluntary running.
American College of Sports Medicine Meeting, Orlando, FL June 1, 2014
MA Linden, RD Sheldon, JA Fletcher, GM Meers, MH Laughlin, JP Thyfault, and RS Rector. Exercise of different
intensities alter hepatic mRNA expression of M1/M2 polarization markers in OLETF rats.
JA Fletcher, GN Ruegsegger, KM Kanosky, FW Booth, JP Thyfault, and RS Rector. Hepatic mitochondrial content
and function in rats selectively bred for high vs. low voluntary running.
JM Crissey, NT Jenkins, KA Duncan, PK Thorne, DS Bayless, VJ Vieira-Potter, RS Rector, JP Thyfault, MH Laughlin,
J Padilla. Adipose Tissue and Vascular Phenotypic Modulation by Voluntary Physical Activity and Dietary Restriction
in Obese Insulin Resistant OLETF Rats.
Invited Oral Presentation Title: Ossabaw Swine: Modeling Childhood Obesity and Fatty Liver Disease. RS Rector.
American Diabetes Association, San Francisco, CA, June 2014
EM Morris, GME Meers, RS Rector, JA Ibdah, LG Koch, SL Britton, JP Thyfault. High Intrinsic Aerobic Capacity
Prevents Development of Insulin Resistance Following Acute High-Fat Diet Challenge. Oral Presentation
The Obesity Society Meeting, Boston, MA, November 2014
EM Morris, S Borengasser, GME Meers, LG Koch, SL Britton, RS Rector, K Shankar, and JP Thyfault. Distinct
Transcriptomic Signatures Associated with Protection Against High Fat Diet-Induced Hepatic Steatosis in Rats with
High Intrinsic Aerobic Capacity.
RS Rector, RD Sheldon, KM Kanosky, MA Linden, KD Wells, L Miles, JW Perfield II, SA Xanthakos, and TH Inge.
Transcriptomic differences in intra-abdominal adipose tissue in extremely obese adolescents with different stages of
nonalcoholic fatty liver disease.
RS Rector, MA Linden, GM Meers, KM Kanosky , M Ruebel, JW Perfield II, JA Ibdah, and FW Booth. Modeling
childhood obesity and nonalcoholic fatty liver disease in juvenile Ossabaw miniature swine fed a western diet.
2015
Experimental Biology, Boston, MA, March 2015
RD Sheldon, MA Linden, GM Meers, EM Morris, MH Laughlin and RS Rector. eNOS Deficiency Increases
Susceptibility to Western Diet Induced Hepatic Mitochondrial Dysfunction. FASEB Journal, Suppl 2015, John Forte
GIL Section Distinguished Abstract Plenary Session
BS Ferguson, TD Olver, RD Sheldon, MA Linden, CA Emter, RS Rector, MH Laughlin. COX Inhibitor Indomethacin
Attenuates Phenylephrine Mediated Vasoconstriction in Rat Aorta. FASEB Journal, Suppl 2015.
TD Olver, BS Ferguson, RD Sheldon, MA Linden, CA Emter, RS Rector and MH Laughlin. Type 2 Diabetes Alters
Nitric Oxide Signaling in the Rat Aorta. FASEB Journal, Suppl 2015.
JL Rowles, JA Fletcher, TM Zidon, RJ Scroggins, Y-Min Park, JW Perfield, JP Thyfault, RS Rector, J Padilla, VJ
Vieira-Potter. Novel effects of FGF21 and exercise on brown adipose tissue inflammation. FASEB Journal, Suppl
2015.
R. Scott Rector
31
American College of Sports Medicine Meeting, San Diego, CA, May 2015
Invited Oral Presentation Title: Intrahepatic Lipids: Systemic Implications and Management with Lifestyle Modification.
RS Rector.
MA Linden, RD Sheldon, GM Meers, EM Morris, JP Thyfault, MH Laughlin, RS Rector. A western diet high in fat,
sucrose, and cholesterol promotes advanced liver disease in sedentary, OLETF rats. Selected Oral Presentation.
MSSE Supplement 2015.
Y-Min Park, RS Rector, T Zidon, J Padilla, R Welly, RJ Scroggins, K Suzanne, SL Britton, LG Koch, GM Meers, FW
Booth, JP Thyfault, JA Kanaley, VJ. Vieira-Potter. Rats bred for high aerobic fitness are protected from ovariectomyinduced insulin resistance during euglycemic clamp. MSSE Supplement 2015.